abter 150mg injection - Alpha-Beta Arteether (150mg/2ml) medicine

Artiz 150mg Injection: Complete Guide to Uses, Side Effects, and Safety

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🏭 Zytras Life Sciences 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for severe malaria.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of the face, lips, or throat
  • Severe rash or blistering of the skin
  • Palpitations, fainting, or chest pain
  • Yellowing of eyes or skin, or dark urine
  • Confusion, seizures, or loss of consciousness
  • Severe abdominal pain or persistent vomiting
  • Decreased urine output or swelling of the body

If experiencing severe symptoms, call emergency services immediately.

What is abter 150mg injection used for?

This medicine is an injectable antimalarial containing Alpha-Beta Arteether 150 mg per 2 ml. It is used for severe falciparum malaria and is given by a healthcare professional as an intramuscular injection, usually once daily for 3 days, followed by oral antimalarial treatment.

  • Generic Name: Alpha-Beta Arteether (150mg/2ml)
  • Manufacturer: Zytras Life Sciences
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 abter 150mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा अल्फा-बीटा आर्टीथर 150 मिलीग्राम/2 मिलीलीटर इंजेक्शन के रूप में उपलब्ध है। इसका उपयोग गंभीर मलेरिया (विशेषकर फाल्सीपेरम मलेरिया) के इलाज के लिए किया जाता है, जब मरीज मुंह से दवा नहीं ले सकता या बेहोश है। यह इंजेक्शन डॉक्टर या नर्स द्वारा मांसपेशी में लगाया जाता है। यह मलेरिया परजीवी को तेजी से मारता है और बुखार व अन्य लक्षणों को कम करता है। इंजेक्शन के बाद डॉक्टर आमतौर पर मुंह से लेने वाली मलेरिया की दवा भी देते हैं ताकि बीमारी पूरी तरह ठीक हो जाए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन लगाने की जगह पर दर्द, लालिमा या सूजन, हल्का बुखार, सिरदर्द, चक्कर आना, जी मिचलाना और पेट में असहजता शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन कभी-कभी तेज एलर्जी, सांस लेने में कठिनाई, दिल की धड़कन में बदलाव, पीलिया या ब्लड शुगर कम हो सकता है। अगर ऐसा कुछ हो तो तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा सिर्फ डॉक्टर या प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही लगाई जानी चाहिए। इसे घर पर खुद न लगाएं। अगर आपको आर्टीमिसिनिन दवाओं से एलर्जी है तो डॉक्टर को पहले बताएं। अपनी सभी दवाओं की जानकारी डॉक्टर को दें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। इंजेक्शन के बाद डॉक्टर जो मुंह से लेने वाली दवा दें, उसे पूरा करें। शराब न पिएं। अगर धड़कन तेज हो, आंखें पीली हों, पेशाब कम आए या सांस लेने में तकलीफ हो तो तुरंत डॉक्टर से मिलें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 abter 150mg injection Uses & Benefits

[{"condition":"Severe falciparum malaria","description":"This medicine is used as a first-line injectable treatment for severe or complicated malaria caused by Plasmodium falciparum, especially when oral therapy is not possible.","evidence":"Well-established"},{"condition":"Complicated malaria with cerebral involvement","description":"It is used in patients with cerebral malaria or other severe manifestations such as impaired consciousness, convulsions, or respiratory distress.","evidence":"Well-established"},{"condition":"Malaria in patients unable to take oral medicines","description":"It is given when vomiting, unconsciousness, or severe weakness prevents the use of oral antimalarial tablets.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Uncomplicated malaria in selected settings","description":"In some settings, injectable artemisinin derivatives may be used when oral therapy is not tolerated, but this is not a standard recommendation.","evidence":"Limited"}]

Primary treatment for: Severe falciparum malaria

Also treats: Cerebral malaria, Complicated malaria with multi-organ involvement

📋 Drug Information

Generic Name(s)Alpha-Beta Arteether (150mg/2ml)
Brand Nameabter 150mg injection
ManufacturerZytras Life Sciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI MALARIALS
Action ClassAntimalarial- Artemisinin and derivatives
Route of AdministrationParenteral (intramuscular injection)
StorageStore in a cool, dry place, protected from light. Do not freeze. Keep out of reach of children. Follow the storage instructions on the pack.
Shelf LifeNot established from the available information. Refer to the expiry date on the pack.
WHO GuidelineThe World Health Organization recommends injectable artemisinin derivatives, including alpha-beta arteether, as first-line treatment for severe falciparum malaria, followed by a full course of oral artemisinin-based combination therapy.
ICMR GuidelineThe Indian Council of Medical Research guidelines also recommend injectable artemisinin derivatives for the management of severe malaria in India, with follow-up oral therapy.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
This medicine must be given only by a trained healthcare professional as a deep intramuscular injection.
2
Always ask the patient about allergies to artemisinin drugs before administering this medicine.
3
Monitor the patient for at least 30 minutes after injection for any allergic reaction.
4
Check blood sugar levels in weak or unconscious patients, as this medicine can rarely cause low blood sugar.
5
Follow up with a full course of oral artemisinin-based combination therapy after the injection course.
6
Advise the patient to avoid alcohol during treatment to reduce liver and heart risks.
7
In patients with heart disease, consider ECG monitoring before and during treatment.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High fever with chills and sweating
This medicine is used for severe malaria, which often presents with high fever.
Likely Use
✅
Unconsciousness or confusion
This medicine is used for cerebral malaria and severe malaria with impaired consciousness.
Likely Use
❌
Mild headache
This medicine is not a primary treatment for mild headache.
Not Primary
❌
Common cold
This medicine is not used for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is given as an intramuscular injection, so it bypasses the digestive system. It is absorbed from the muscle into the bloodstream, but the exact absorption rate is not well established from the available information.
DistributionAfter absorption, this medicine is distributed to body tissues, including the blood, liver, and other organs. The exact volume of distribution is not established from the available information.
Protein BindingNot established from the available information.
MetabolismThis medicine is metabolized in the liver, mainly by cytochrome P450 enzymes, into less active metabolites. The exact enzymes involved are not fully established from the available information.
Half-LifeNot established from the available information.
ExcretionThe metabolites of this medicine are excreted mainly in the bile and urine. The exact proportions are not established from the available information.
BioavailabilityNot established from the available information.
Onset of ActionThe antimalarial effect begins within a few hours after intramuscular injection, with rapid reduction in parasite load.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe effect lasts for about 24 hours after a single dose, which is why the injection is usually given once daily for a few days.

How It Works

Alpha-Beta Arteether is an artemisinin derivative that kills malaria parasites through a unique mechanism. Inside the parasite, the artemisinin molecule is activated by iron-containing heme molecules that are released when the parasite digests hemoglobin. This activation produces highly reactive free radicals and carbon-centered radicals that damage parasite proteins, membranes, and essential enzymes. The parasite's ability to survive and multiply is rapidly destroyed, leading to clearance of the parasite from the blood. This medicine is effective against the blood stages of Plasmodium falciparum, including the stages that cause severe disease.

Mechanism Steps

1
Activation by heme iron: Inside the malaria parasite, the artemisinin molecule reacts with iron-containing heme released during hemoglobin digestion, which activates the drug.
2
Generation of free radicals: The activated drug forms highly reactive free radicals and carbon-centered radicals that are toxic to the parasite.
3
Damage to parasite proteins and membranes: These radicals damage essential parasite proteins, enzymes, and cell membranes, disrupting the parasite's metabolism and survival.
4
Parasite death and clearance: The damaged parasites are rapidly destroyed and cleared from the bloodstream, reducing the parasite burden and relieving symptoms.

💡 How to Take abter 150mg injection

Strength: Injection: Alpha-Beta Arteether 150 mg per 2 ml

1This medicine is given by a healthcare professional as a deep intramuscular injection.
2You do not need to do anything to prepare for the injection except inform the doctor about your allergies and other medicines.
3The injection is usually given in the buttock or thigh muscle.
4After the injection, you may be asked to stay for a short while for observation.
5Follow your doctor's instructions for follow-up oral treatment and rest.
6Do not rub or massage the injection site vigorously.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 150 mg given by deep intramuscular injection once daily for 3 days. The exact dose and duration must be individualized by a qualified clinician based on the severity of malaria, body weight, kidney and liver function, and response to treatment. This medicine is not for self-administration. After the injection course, oral antimalarial therapy is usually prescribed to complete treatment.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. The dose should be individualized by a clinician based on kidney and liver function, heart condition, and other medicines being taken.
Renal ImpairmentNo specific dose adjustment guidelines are established from the available information. Use with caution in patients with kidney disease, and the doctor will decide the appropriate dose.
Hepatic ImpairmentNo specific dose adjustment guidelines are established from the available information. Use with caution in patients with liver disease, and the doctor will decide the appropriate dose.
Maximum Daily DoseThe maximum daily dose is not established from the available information. The dose must be determined by a qualified clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing needed
This medicine is given as an injection, so food timing does not affect it.
Grapefruit
Avoid
Grapefruit can affect liver enzymes and may alter drug levels.
Alcohol
Avoid
Alcohol may increase the risk of liver problems and dizziness.

⏰ What to Do If You Miss a Dose

📌 You miss a scheduled injection appointment
→ Contact your doctor or clinic as soon as possible to reschedule.
💡 Do not try to self-administer or double the dose.
📌 You forget to take your follow-up oral antimalarial tablets
→ Take the missed dose as soon as you remember, unless it is almost time for the next dose.
💡 Do not double dose. Consult your doctor if unsure.

⚠️ Side Effects of abter 150mg injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply a cold compress if needed. Inform your nurse or doctor if pain is severe.
Fever (Common (5-10%))
Fever may be due to malaria itself. Take paracetamol if prescribed and drink plenty of fluids.
Headache (Common (5-10%))
Rest and stay hydrated. Consult your doctor if headache is severe or persistent.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you feel normal. Lie down if dizzy.
Nausea (Uncommon (1-5%))
Eat small, light meals. Inform your doctor if vomiting occurs.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical help if you notice rash, swelling of face or throat, difficulty breathing, or a sudden drop in blood pressure.
Heart rhythm abnormalities (Rare (<0.1%))
Report palpitations, fainting, or chest discomfort immediately. An ECG may be needed.
Liver enzyme elevation (Rare (<0.1%))
Inform your doctor if you notice yellowing of eyes or skin, dark urine, or severe fatigue. Liver function tests may be advised.
Low blood sugar (hypoglycemia) (Rare (<0.1%))
If you feel sweaty, shaky, confused, or very weak, tell your nurse or doctor immediately. Blood sugar may need to be checked.

⚠️ Rare Side Effects

Severe skin reactions
Seek immediate medical attention if you develop a severe rash with blisters or peeling skin.
Seizures
This requires emergency medical care. Inform the doctor about all medicines you have received.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Mefloquine Major
Lumefantrine Major
Rifampicin Moderate
Ketoconazole Moderate
Warfarin Moderate
Paracetamol Minor

🚨 Major Interactions

  • Other antimalarials (e.g., mefloquine, lumefantrine)
  • Drugs that prolong QT interval (e.g., certain antibiotics, antipsychotics)

⚡ Moderate Interactions

  • Liver enzyme inducers (e.g., rifampicin, carbamazepine)
  • Liver enzyme inhibitors (e.g., ketoconazole, ritonavir)

🍷 Alcohol Interaction

Avoid alcohol while receiving this medicine. Alcohol can increase the risk of liver side effects, dizziness, and low blood sugar. It may also worsen your general condition during malaria treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to alpha-beta arteether or other artemisinin derivatives","First trimester of pregnancy (unless clearly needed)","Severe liver disease with impaired function","Use without medical supervision"]

⚠️ Warnings & Precautions

["This medicine must be given only by a healthcare professional.","Do not self-administer or use at home.","Inform your doctor about all other medicines you are taking.","Use with caution in patients with heart disease or electrolyte imbalance.","Monitor blood sugar in patients who are weak or not eating.","Follow up with oral antimalarial treatment as prescribed.","Avoid alcohol during treatment.","Report any unusual symptoms immediately."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Breastfeeding mothers should consult their doctor before receiving this medicine. If used, the doctor may advise monitoring the baby for any unusual symptoms.

💊 Overdose Management

Overdose of this medicine is unlikely because it is given by a healthcare professional. If an overdose is suspected, seek immediate medical attention. Treatment is supportive and may include monitoring of heart rhythm, blood pressure, blood sugar, and liver function. There is no specific antidote.

⏰ Missed Dose

Since this medicine is given by a healthcare professional, missed doses are unlikely. If you miss a scheduled injection, contact your doctor or clinic as soon as possible to reschedule. Do not try to self-administer a double dose.

Additional Safety Advice

General Safety

This medicine must be given only by a qualified healthcare professional in a setting where emergency care is available. Do not attempt to self-inject or take this medicine at home. Tell your doctor if you are allergic to artemisinin medicines or have had a previous reaction to any antimalarial drug. Inform your doctor about all other medicines you are taking, especially heart medicines, antibiotics, and blood thinners. This medicine is not recommended during the first trimester of pregnancy unless the doctor decides the benefit clearly outweighs the risk. If you are breastfeeding, discuss with your doctor before receiving this medicine. After the injection course, your doctor will usually prescribe oral antimalarial tablets to complete the treatment and prevent relapse. Do not skip follow-up visits, and report any new symptoms such as palpitations, yellowing of eyes, or dark urine immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more prone to side effects such as dizziness, low blood sugar, and heart rhythm changes. Close monitoring is advised. The dose should be individualized by the doctor based on kidney and liver function and other medical conditions.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, discuss with your doctor before receiving this medicine. It is generally avoided in the first trimester. If you become pregnant during treatment, inform your doctor immediately.

🏥 Post-Surgery Considerations

If you have recently had surgery, inform your surgeon and anesthesiologist about this medicine. It may interact with other medicines and affect heart rhythm. Your doctor will decide the safest approach.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine. There are no specific dental precautions, but your dentist may need to know about your overall health and medicines.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest during and after treatment.
🥗
Drink plenty of fluids to stay hydrated.
😴
Eat light, nutritious meals to help your body recover.
💧
Avoid alcohol and smoking during treatment.
🧘
Use mosquito nets and repellents to prevent re-infection.
🌞
Complete the full course of oral antimalarial tablets as prescribed.
🚭
Attend all follow-up appointments.

🏋️ Exercise Considerations

Avoid strenuous exercise until you have fully recovered from malaria. Rest is important. Once you feel better, gradually return to your normal activities. Consult your doctor before starting any heavy exercise.

🥗 Diet Recommendations

Eat light, easily digestible foods like khichdi, soup, and fruits.
Stay well hydrated with water, oral rehydration solutions, and fresh juices.
Include protein-rich foods like eggs, dal, and lean meat to aid recovery.
Avoid oily, spicy, and processed foods.
Avoid alcohol and caffeine.

💼 Impact on Daily Work & Life

You may feel weak and dizzy for a few days after treatment. Avoid driving or operating heavy machinery until you feel fully alert. Take rest from work as advised by your doctor. Most people can return to normal activities within a week after completing treatment.

🛑 When to Stop This Medicine

Do not stop this medicine on your own. The full course of injections and follow-up oral tablets must be completed as prescribed by your doctor. If you experience serious side effects, your doctor will decide whether to stop or change the treatment.

📅 Long-Term Use Effects

This medicine is usually given for a short course of 3 days, so long-term effects are not common. Rarely, it may cause liver enzyme changes or heart rhythm abnormalities. Follow-up with your doctor is important to ensure complete cure and to monitor for any delayed side effects. Long-term use without medical supervision is not recommended.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral artemisinin-based combination therapy

Used for uncomplicated malaria when the patient can take oral medicines.

Evidence: Well-established
Intravenous artesunate

Another injectable artemisinin derivative used for severe malaria.

Evidence: Well-established
Quinine injection

An older injectable antimalarial used when artemisinin derivatives are not available.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no specific vaccine interactions reported with this medicine. However, if you are due for any vaccination, inform your doctor. Live vaccines may be avoided during acute illness.

📦 Storage Guide

✅ DO

Store in a cool, dry place, protected from light.

❌ DON'T

Do not freeze the injection.

✅ DO

Keep in the original container.

❌ DON'T

Do not transfer to another container.

✅ DO

Keep out of reach of children.

❌ DON'T

Do not use after the expiry date.

✈️ Traveling with This Medicine

If you are prescribed this medicine while traveling, it must be administered by a healthcare professional. Carry a copy of your prescription and medical records. This injection is not for self-administration. If you are traveling to a malaria-endemic area, take preventive measures and seek medical help immediately if you develop fever. Store the injection as directed on the pack and do not expose it to extreme temperatures.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with severe falciparum malaria and vomiting
He was admitted to the hospital with high fever and could not take oral medicines. He received this injection once daily for 3 days. His fever settled and parasite count dropped rapidly. After discharge, he completed a course of oral antimalarial tablets and recovered fully.
💡 Lesson: Injectable antimalarials are life-saving in severe malaria when oral therapy is not possible, but follow-up oral treatment is essential.
👤 A 28-year-old pregnant woman in her second trimester with severe malaria
She was treated with this injection under close medical supervision after weighing the risks and benefits. She responded well, and both mother and baby remained stable. She was advised regular follow-up.
💡 Lesson: Use of this medicine in pregnancy requires careful assessment by a doctor, and close monitoring is important.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within a few hours after the injection. Fever and other symptoms usually improve within 24 to 48 hours, but complete recovery requires the full course and follow-up oral treatment.

Q: Can I take this medicine at home?

A: No, this medicine must be given only by a trained healthcare professional in a clinic or hospital setting. It is not for self-administration.

Q: What are the common side effects?

A: Common side effects include pain at the injection site, mild fever, headache, dizziness, and nausea. These usually settle on their own.

Q: Is this medicine safe in pregnancy?

A: It is generally avoided in the first trimester unless clearly needed. In later pregnancy, it may be used if the doctor decides the benefit outweighs the risk. Always consult your doctor.

Q: Can I drink alcohol while taking this medicine?

A: No, alcohol should be avoided during treatment as it can increase the risk of liver problems, dizziness, and low blood sugar.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How many days do I need this injection?
  • What if I miss a dose?
  • Can I drink alcohol while on this medicine?
  • Is this medicine safe in pregnancy?
  • Does this medicine affect my heart?
  • What should I eat during treatment?

🔄 Substitutes for abter 150mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This injection can be self-administered at home.
    Fact: No, this medicine must be given only by a trained healthcare professional in a clinic or hospital setting.
  • Myth: This injection alone cures malaria completely.
    Fact: This injection treats the acute severe phase, but follow-up oral antimalarial treatment is needed to prevent relapse.
  • Myth: This medicine is safe in pregnancy without any risk.
    Fact: It is generally avoided in the first trimester unless clearly needed. Always consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Alpha-Beta Arteether 150 mg/2 ml injection

Brand Alternatives

  • Artiz 150mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Alpha-Beta Arteether injection","class":"Artemisinin derivative","route":"Intramuscular","main_use":"Severe falciparum malaria","note":"Given once daily for 3 days."},{"medicine":"Artesunate injection","class":"Artemisinin derivative","route":"Intravenous or intramuscular","main_use":"Severe falciparum malaria","note":"Preferred first-line in many guidelines."},{"medicine":"Artemether injection","class":"Artemisinin derivative","route":"Intramuscular","main_use":"Severe falciparum malaria","note":"Given once daily for 3 days."}]

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