Abivom 4mg Injection - Uses, Price, Side Effects
What is abivom 4mg injection used for?
Abivom 4mg Injection contains Ondansetron, a serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, or surgery. It works by blocking serotonin, a natural substance that can cause vomiting.
- Generic Name: Ondansetron
- Manufacturer: Associated Biopharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ abivom 4mg injection Uses & Benefits
Prevention of nausea and vomiting associated with highly emetogenic cancer chemotherapy; prevention of postoperative nausea and vomiting; prevention of radiotherapy-induced nausea and vomiting.
Off-label uses: Treatment of hyperemesis gravidarum; management of pruritus in cholestasis; treatment of serotonin syndrome (limited evidence).
๐ Drug Information
| Generic Name(s) | Ondansetron |
| Brand Name | Anset 4mg Tablet MD |
| Manufacturer | Associated Biopharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Serotonin antagonists (5-HT3 antagonists) |
| Route of Administration | Oral (tablet, orally disintegrating tablet, oral solution); intravenous; intramuscular. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Selective antagonist of serotonin 5-HT3 receptors, blocking serotonin binding in the chemoreceptor trigger zone (CTZ) and gastrointestinal tract, thereby preventing nausea and vomiting.
Mechanism Steps
๐ก How to Take abivom 4mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of abivom 4mg injection
โ Common Side Effects
- Headache
- Constipation
- Fatigue
- Dizziness
- Diarrhea
๐จ Serious Side Effects
- QT prolongation
- Torsades de pointes
- Serotonin syndrome
- Hypersensitivity reactions (including anaphylaxis)
- Bronchospasm
โ ๏ธ Rare Side Effects
- Transient liver enzyme elevation
- Blurred vision
- Extrapyramidal reactions (dystonia, oculogyric crisis)
- Hypokalemia
- Hypomagnesemia
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Apomorphine | Major | Severe hypotension and loss of consciousness |
| Tramadol | Moderate | Increased risk of serotonin syndrome |
| SSRIs | Moderate | Increased risk of serotonin syndrome |
๐จ Major Interactions
- Apomorphine
- Tramadol
- Serotonergic drugs (e.g., SSRIs, SNRIs, MAOIs)
โก Moderate Interactions
- QTc-prolonging agents (e.g., class IA/III antiarrhythmics, certain antipsychotics)
- CYP2D6 substrates (e.g., codeine, metoprolol)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
โน๏ธ Minor Interactions
- Antacids
- Cimetidine
๐ฝ๏ธ Food Interactions
No significant food interactions; may be taken with or without food.
๐ท Alcohol Interaction
Alcohol may increase sedative effects; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to ondansetron or any component; concomitant use with apomorphine; congenital long QT syndrome.
๐ Monitoring Parameters
ECG (QT interval) in patients at risk; liver function tests if symptoms of hepatotoxicity; electrolyte levels (potassium, magnesium) before IV administration.
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; caution advised; consider risk-benefit.
๐ Overdose Management
Supportive care; monitor ECG for QT prolongation; no specific antidote; hemodialysis not effective.
โฐ Missed Dose
If a dose is missed, take it as soon as remembered unless it is almost time for the next dose; do not double dose.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for abivom 4mg injection
View AllAlternative brands with exact same active ingredient (Ondansetron (4mg)):
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Medical Note: Always consult your doctor before switching medications.