abendol plus syrup - Uses, Price, Side Effects & Substitutes
What is abendol plus syrup used for?
ABD Plus Tablet (Ivermectin + Albendazole) is used to treat Filariasis. It contains Ivermectin (1.5mg/5ml) + Albendazole (200mg/5ml), which Ivermectin: binds to glutamate-gated chloride channels in nerve and muscle cells. Always consult your doctor before use. Take as prescribed.
- Generic Name: Ivermectin + Albendazole
- Manufacturer: Leeford Healthcare Ltd
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 abendol plus syrup के बारे में संक्षिप्त जानकारी (Hindi Summary)
abendol plus syrup का उपयोग मुख्य रूप से anti infectives और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Ivermectin (1.5mg/5ml) + Albendazole (200mg/5ml) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
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📋 Drug Information
| Generic Name(s) | Ivermectin + Albendazole |
|---|---|
| Brand Name | ABD Plus Tablet |
| Manufacturer | Leeford Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Anthelmintics |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25°C), protect from light and moisture |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
💡 How and when to take abendol plus syrup?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at room temperature (20-25°C), protect from light and moisture
⚙️ How abendol plus syrup Works
Ivermectin: binds to glutamate-gated chloride channels in nerve and muscle cells, causing hyperpolarization and paralysis; Albendazole: inhibits tubulin polymerization, disrupting microtubule formation and glucose uptake
💊 abendol plus syrup Uses in Hindi (Ke Fayde), Benefits & Indications
Filariasis, strongyloidiasis, ascariasis, hookworm, trichuriasis, enterobiasis
Off-label uses: Scabies, lice, cutaneous larva migrans
⚠️ What are the side effects of abendol plus syrup?
✅ Common Side Effects
- Nausea
- vomiting
- diarrhea
- abdominal pain
- headache
- dizziness
🚨 Serious Side Effects
- Hepatotoxicity
- Stevens-Johnson syndrome
- agranulocytosis
- seizures
⚠️ Rare Side Effects
- Alopecia
- acute renal failure
- pancreatitis
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Theophylline | Major | Increased theophylline toxicity |
| Ketoconazole | Major | Increased ivermectin/albendazole levels |
| Rifampin | Moderate | Decreased albendazole levels |
| Grapefruit juice | Minor | Altered metabolism |
🚨 Major Interactions
- Warfarin
- Theophylline
- CYP3A4 inhibitors (e.g., ketoconazole)
⚡ Moderate Interactions
- CYP3A4 inducers (e.g., rifampin)
- P-glycoprotein inhibitors
ℹ️ Minor Interactions
- Grapefruit juice
🍽️ Food Interactions
Fatty meal increases absorption of albendazole; avoid grapefruit juice
🍷 Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
🛡️ Safety & Warnings
🚫 Contraindications
Hypersensitivity, pregnancy, lactation, hepatic impairment
📊 Monitoring Parameters
Liver function tests, renal function, blood counts
🤱 Lactation Safety
Not recommended; excreted in breast milk
💊 Overdose Management
Symptomatic and supportive; gastric lavage if recent
⏰ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose
🛑 Myths vs. Facts about abendol plus syrup
- Myth: Generic substitutes of abendol plus syrup are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Ivermectin (1.5mg/5ml) + Albendazole (200mg/5ml)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of abendol plus syrup can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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