abel 80 tablet - Azilsartan medoxomil (80mg) medicine

abel 80 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Lupin Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 23, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 23, 2026

What is abel 80 tablet used for?

Abel 40 Tablet (Azilsartan medoxomil) is used to treat CARDIAC. It contains Azilsartan medoxomil (80mg), which Selective angiotensin II receptor blocker (ARB) that blocks the vasoconstrictor . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Azilsartan medoxomil
  • Manufacturer: Lupin Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š abel 80 tablet Uses & Benefits

Hypertension (alone or in combination with other antihypertensives).

Off-label uses: Diabetic nephropathy, heart failure (limited data).

๐Ÿ“‹ Drug Information

Generic Name(s)Azilsartan medoxomil
Brand NameAbel 40 Tablet
ManufacturerLupin Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin receptor blockers(ARB)
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from moisture and light.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentration reached in 1.5-3 hours.
DistributionExtensively distributed; volume of distribution approximately 16 L.
Protein Binding>99% bound to plasma proteins, primarily albumin.
MetabolismMetabolized primarily via CYP2C9 to inactive metabolites; also undergoes glucuronidation.
Half-LifeApproximately 11 hours.
Excretion55% via feces, 42% via urine.
BioavailabilityApproximately 60%.
Onset of ActionWithin 2 weeks of therapy.
Peak Plasma Time1.5-3 hours.
Duration of Action24 hours.

How It Works

Selective angiotensin II receptor blocker (ARB) that blocks the vasoconstrictor and aldosterone-secreting effects of angiotensin II.

Mechanism Steps

1Azilsartan medoxomil is a prodrug that is hydrolyzed to azilsartan during absorption.
2Azilsartan selectively binds to the angiotensin II type 1 (AT1) receptor.
3Blockade of AT1 receptor prevents angiotensin II-mediated vasoconstriction.

๐Ÿ’ก How to Take abel 80 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of abel 80 tablet

โœ… Common Side Effects

  • Dizziness
  • Diarrhea
  • Fatigue
  • Upper respiratory tract infection

๐Ÿšจ Serious Side Effects

  • Hypotension
  • Hyperkalemia
  • Renal impairment
  • Angioedema

โš ๏ธ Rare Side Effects

  • Hepatotoxicity
  • Neutropenia
  • Anaphylactic reaction

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
NSAIDs Major Reduced antihypertensive effect; increased risk of renal impairment
Lithium Major Increased lithium levels and toxicity
Potassium-sparing diuretics Major Increased risk of hyperkalemia
ACE inhibitors Major Increased risk of hypotension, hyperkalemia, renal dysfunction
Antidiabetic agents Moderate Enhanced hypoglycemic effect
Digoxin Moderate Possible increase in digoxin levels
Warfarin Moderate No significant interaction reported; monitor INR
Antacids Minor Slight decrease in absorption; separate dosing
Cimetidine Minor No clinically significant interaction

๐Ÿšจ Major Interactions

  • NSAIDs
  • Lithium
  • Potassium-sparing diuretics
  • ACE inhibitors

โšก Moderate Interactions

  • Antidiabetic agents
  • Digoxin
  • Warfarin

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions; may be taken with or without food.

๐Ÿท Alcohol Interaction

May potentiate hypotensive effects; avoid excessive alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to azilsartan; concomitant use with aliskiren in patients with diabetes; severe hepatic impairment; pregnancy.

๐Ÿ“Š Monitoring Parameters

Blood pressure, renal function, serum potassium, liver enzymes.

๐Ÿคฑ Lactation Safety

Not recommended; excreted in animal milk, unknown in humans.

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; hypotension may be managed with IV fluids and vasopressors.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 23, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for abel 80 tablet

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Alternative brands with exact same active ingredient (Azilsartan medoxomil (80mg)):

Medical Note: Always consult your doctor before switching medications.

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