A2F 5 mg/10 mg Tablet - Uses, Price, Side Effects
What is a2f 5 mg/10 mg tablet used for?
A2F 5 mg/10 mg Tablet is a combination of Amlodipine (a calcium channel blocker) and Atorvastatin (a statin). It is used to treat high blood pressure and high cholesterol, reducing the risk of heart attack and stroke. Amlodipine relaxes blood vessels, while Atorvastatin lowers LDL cholesterol.
- Generic Name: Amlodipine + Atorvastatin
- Manufacturer: Zydus Cadila
- Medicine Form: Allopathy
- Pregnancy Category: A
🇮🇳 a2f 5 mg/10 mg tablet के बारे में संक्षिप्त जानकारी (Hindi Summary)
a2f 5 mg/10 mg tablet का उपयोग मुख्य रूप से cardiac और उससे जुड़ी समस्याओं के इलाज के लिए किया जाता है। इस दवा में मुख्य सामग्री के रूप में Amlodipine (5mg) + Atorvastatin (10mg) मौजूद है। इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए, खासकर गर्भावस्था (pregnancy) और लिवर (liver) की समस्याओं में।
मुख्य फायदे (Key Benefits): Detailed medical information is being added to our database.... Read more below.
📋 Drug Information
| Generic Name(s) | Amlodipine + Atorvastatin |
|---|---|
| Brand Name | Amat 5mg/10mg tablet |
| Manufacturer | Zydus Cadila |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Calcium channel blocker + HMG-CoA reductase inhibitor |
| Route of Administration | Oral |
| Storage | Store at 20-25°C (68-77°F), protect from light and moisture |
| Shelf Life | As per manufacturer |
🔬 Pharmacology (PK/PD)
Pharmacokinetics
Pharmacodynamics
📅 When to take a2f 5 mg/10 mg tablet?
💡 How and when to take a2f 5 mg/10 mg tablet?
Follow your doctor's prescription exactly.
- ✅ Take exactly as prescribed by your doctor.
- ✅ Do not exceed the recommended dose
- ✅ Complete the full course of medication
- ✅ Store at 20-25°C (68-77°F), protect from light and moisture
⚙️ How a2f 5 mg/10 mg tablet Works
Amlodipine inhibits calcium influx across cell membranes in vascular smooth muscle and cardiac muscle, causing vasodilation and reduced peripheral resistance. Atorvastatin inhibits HMG-CoA reductase, reducing cholesterol synthesis and increasing LDL receptor expression.
💊 a2f 5 mg/10 mg tablet Uses in Hindi (Ke Fayde), Benefits & Indications
Hypertension, coronary artery disease, hyperlipidemia, prevention of cardiovascular events
Off-label uses: Chronic stable angina, vasospastic angina, pediatric hypertension (amlodipine); primary prevention of cardiovascular disease (atorvastatin)
⚠️ What are the side effects of a2f 5 mg/10 mg tablet?
✅ Common Side Effects
- Edema (peripheral)
- Dizziness
- Fatigue
- Headache
- Nausea
- Diarrhea
- Myalgia
- Arthralgia
🚨 Serious Side Effects
- Rhabdomyolysis
- Myopathy
- Hepatotoxicity
- Angioedema
- Stevens-Johnson syndrome
- Hypotension
⚠️ Rare Side Effects
- Peripheral neuropathy
- Gynecomastia
- Tinnitus
- Alopecia
- Erythema multiforme
Consult your doctor if you experience any unusual symptoms.
🔄 Best Substitutes for a2f 5 mg/10 mg tablet
View AllAlternative medicines with exact same composition and strength (Amlodipine (5mg) + Atorvastatin (10mg)):
- a2 5mg/10mg tabletZydus Cadila₹32.12💰 59.6% CHEAPER
- a2 5 mg/10 mg tabletZydus Cadila₹37.52💰 52.8% CHEAPER
- amat 5mg/10mg tabletAbbott₹40.00💰 49.7% CHEAPER
- amlochol 5 mg/10 mg tabletAristo Pharmaceuticals Pvt Ltd₹46.43💰 41.6% CHEAPER
- zivast-am tabletFDC Ltd₹47.00💰 40.9% CHEAPER
- lipikind am 5 mg/10 mg tabletMankind Pharma Ltd₹47.55💰 40.2% CHEAPER
- amtor 5 mg/10 mg tabletAlembic Pharmaceuticals Ltd₹52.88💰 33.5% CHEAPER
- stator am 5mg/10mg tabletAbbott₹53.54💰 32.7% CHEAPER
- ovas st 5mg/10mg tabletProtech Telelinks₹59.00💰 25.8% CHEAPER
- bettor am tabletBrilliant Lifesciences Pvt Ltd₹60.94💰 23.4% CHEAPER
Medical Note: Always consult your doctor before switching medications. Generic alternatives with same salts are therapeutically equivalent.
🔬 Drug Interactions
| ⚠️ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Grapefruit juice | Moderate | Increased atorvastatin levels |
| Macrolide antibiotics | Moderate | Increased risk of myopathy |
| Antifungals (azole) | Moderate | Increased atorvastatin levels |
| Beta-blockers | Minor | Additive blood pressure lowering |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., itraconazole, ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampin, phenytoin)
- Grapefruit juice
- Cyclosporine
- Gemfibrozil
- Fibrates
- Niacin (lipid-lowering doses)
⚡ Moderate Interactions
- Digoxin
- Warfarin
- Oral contraceptives
- Antacids
- Colchicine
ℹ️ Minor Interactions
- Cimetidine
- Ranitidine
- Magnesium supplements
🍽️ Food Interactions
Grapefruit juice increases amlodipine and atorvastatin levels; avoid, High-fat meal decreases atorvastatin absorption
🍷 Alcohol Interaction
May enhance hypotensive effect; avoid excessive alcohol
🛡️ Safety & Warnings
🚫 Contraindications
Active liver disease, unexplained persistent elevations of serum transaminases, pregnancy, lactation, hypersensitivity to any component
📊 Monitoring Parameters
Blood pressure, heart rate, serum lipids, liver function tests, signs of myopathy
🤱 Lactation Safety
Not recommended; atorvastatin excreted in milk, amlodipine unknown
💊 Overdose Management
Supportive care; activated charcoal if recent; monitor blood pressure and heart rate; treat hypotension with vasopressors; atorvastatin overdose: supportive
⏰ Missed Dose
Take as soon as remembered unless near next dose; do not double dose
🛑 Myths vs. Facts about a2f 5 mg/10 mg tablet
- Myth: Generic substitutes of a2f 5 mg/10 mg tablet are less effective.
Fact: Approved generic medicines contain the exact same active ingredients (Amlodipine (5mg) + Atorvastatin (10mg)) and are just as safe and effective as the branded version. - Myth: Taking a double dose will cure my symptoms faster.
Fact: Taking more than the prescribed dose of a2f 5 mg/10 mg tablet can lead to severe toxicity or an overdose. Stick strictly to your doctor's dosage. - Myth: This medicine is 100% safe for everyone.
Fact: No medicine is universally safe. Safety depends on your medical history, ongoing medicines, and potential allergies. Always consult a doctor.
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