zantof lb 200mg tablet - Ofloxacin (200mg) + Lactobacillus (60Million spores) medicine

A Flox 200mg Tablet: Complete Medicine Guide

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🏭 Nexus India 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 22, 2026
🤰 Pregnancy Category Ofloxacin is not recommended during pregnancy unless the potential benefit justifies the potential risk to the fetus. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 22, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden pain, swelling, or inability to move a joint (possible tendon rupture).
  • Numbness, tingling, or burning in hands or feet (peripheral neuropathy).
  • Severe diarrhea, especially if bloody (possible C. difficile infection).
  • Seizures, confusion, or hallucinations.
  • Difficulty breathing, swelling of face, lips, or throat (severe allergic reaction).
  • Yellowing of skin or eyes, dark urine (liver problems).
  • Irregular heartbeat or fainting (QT prolongation).

If experiencing severe symptoms, call emergency services immediately.

What is zantof lb 200mg tablet used for?

This medicine is a combination of Ofloxacin, an antibiotic, and Lactobacillus, a probiotic. It is used to treat various bacterial infections and helps restore gut flora.

  • Generic Name: Ofloxacin (200mg) + Lactobacillus (60Million spores)
  • Manufacturer: Nexus India
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 zantof lb 200mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ओफ्लोक्सासिन और लैक्टोबैसिलस का संयोजन है। यह बैक्टीरियल संक्रमणों जैसे मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण और कुछ यौन संचारित संक्रमणों के इलाज के लिए उपयोग की जाती है। लैक्टोबैसिलस आंतों में अच्छे बैक्टीरिया को बनाए रखने में मदद करता है।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, दस्त, सिरदर्द, चक्कर आना और पेट में दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें टेंडन टूटना, तंत्रिका क्षति, दौरे और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। एंटासिड, आयरन या जिंक सप्लीमेंट के साथ इस दवा को न लें; कम से कम 2 घंटे का अंतराल रखें। शराब का सेवन न करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। धूप से बचें और सनस्क्रीन का उपयोग करें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 zantof lb 200mg tablet Uses & Benefits

[{"condition":"Urinary tract infections","description":"Used to treat uncomplicated and complicated urinary tract infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Effective against bacterial bronchitis and pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for infections such as cellulitis and abscesses caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Sexually transmitted infections","description":"Effective against gonorrhea and chlamydia when caused by susceptible strains.","evidence":"Well-established"},{"condition":"Prostatitis","description":"Used to treat bacterial prostatitis caused by susceptible bacteria.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes prescribed off-label for severe traveler's diarrhea caused by susceptible bacteria.","evidence":"Limited"},{"condition":"Epididymitis","description":"May be used off-label for epididymitis in certain cases.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Sexually transmitted infections

📋 Drug Information

Generic Name(s)Ofloxacin (200mg) + Lactobacillus (60Million spores)
Brand Namezantof lb 200mg tablet
ManufacturerNexus India
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a full glass of water, with or without food.
2
Complete the full course as prescribed, even if you feel better.
3
Avoid taking antacids, iron, or zinc supplements within 2 hours of this medicine.
4
Do not consume alcohol while taking this medicine.
5
If you experience tendon pain, swelling, or numbness, stop the medicine and contact your doctor immediately.
6
Stay well hydrated throughout the day.
7
Inform your doctor if you have kidney or liver problems before starting this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Burning sensation during urination
This medicine is commonly prescribed for urinary tract infections.
Likely Use
✅
Cough with fever
May be used for respiratory tract infections.
Likely Use
✅
Skin redness and swelling
Used for skin and soft tissue infections.
Likely Use
❌
Runny nose
This medicine is not effective for viral infections like the common cold.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionOfloxacin is rapidly and well absorbed from the gastrointestinal tract after oral administration. Bioavailability is approximately 85-95%. Food may slightly delay absorption but does not significantly reduce the extent of absorption.
DistributionOfloxacin is widely distributed throughout the body. It penetrates well into tissues, including lung, kidney, prostate, and skin. It also crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 20-30% bound to plasma proteins.
MetabolismOfloxacin is minimally metabolized in the liver. Only a small fraction is metabolized to inactive metabolites.
Half-LifeThe elimination half-life is approximately 4-5 hours in patients with normal renal function.
ExcretionOfloxacin is primarily excreted unchanged in the urine by glomerular filtration and tubular secretion. About 70-80% of an oral dose is recovered in urine as unchanged drug.
BioavailabilityApproximately 85-95%
Onset of ActionPeak plasma concentrations are reached within 1-2 hours after oral administration.
Peak Plasma Time1-2 hours
Duration of ActionThe antibacterial effect lasts for approximately 12 hours, allowing for twice-daily dosing.

How It Works

Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination. This leads to the inhibition of bacterial cell division and ultimately bacterial death. Lactobacillus, a probiotic, helps maintain the natural gut flora and may reduce the risk of antibiotic-associated diarrhea.

Mechanism Steps

1
Entry into bacterial cell: Ofloxacin penetrates the bacterial cell wall and enters the cytoplasm.
2
Inhibition of DNA gyrase: Ofloxacin binds to DNA gyrase, preventing the supercoiling of DNA necessary for replication.
3
Inhibition of topoisomerase IV: Ofloxacin also inhibits topoisomerase IV, which is involved in separating daughter DNA strands during cell division.
4
Bacterial cell death: The inhibition of these enzymes leads to the inability of bacteria to replicate and repair DNA, resulting in bacterial death.
5
Probiotic effect: Lactobacillus spores germinate in the gut and help restore beneficial bacteria, potentially reducing antibiotic-associated diarrhea.

💡 How to Take zantof lb 200mg tablet

Strength: Ofloxacin 200mg + Lactobacillus 60 million spores immediate-release tablet

1Take the tablet with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with or without food, but if stomach upset occurs, take with food.
4Take at evenly spaced intervals, usually every 12 hours.
5Do not take antacids, iron, or zinc within 2 hours of this medicine.
6Complete the full course as prescribed, even if you feel better.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet (Ofloxacin 200mg) twice daily, or as prescribed by your doctor. The dose and duration depend on the type and severity of the infection, your kidney function, and other factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Use with caution due to increased risk of tendon rupture and CNS effects.
Renal ImpairmentDose adjustment is required in patients with renal impairment. For creatinine clearance 20-50 mL/min, the usual dose may be given once daily. For creatinine clearance <20 mL/min, the dose may need further reduction. Consult your doctor.
Hepatic ImpairmentNo specific dose adjustment is required for hepatic impairment, but use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is 400mg of ofloxacin. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals if stomach upset occurs
Reduces nausea and abdominal discomfort.
Dairy products
Avoid taking together
Calcium can reduce absorption of ofloxacin.
Caffeine
Limit intake
May increase caffeine side effects.

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of zantof lb 200mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or bloody, contact your doctor immediately.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe, consult your doctor.

🚨 Serious Side Effects

Tendon rupture (Rare (<0.1%))
Seek immediate medical attention if you experience sudden pain, swelling, or inability to move a joint.
Peripheral neuropathy (Rare (<0.1%))
Report symptoms such as numbness, tingling, burning, or weakness in the hands or feet to your doctor immediately.
Central nervous system effects (Rare (<0.1%))
Seek medical help if you experience seizures, confusion, hallucinations, or severe headaches.
Severe allergic reactions (Rare (<0.1%))
Get emergency help if you have difficulty breathing, swelling of face, lips, tongue, or throat, or a severe rash.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Contact your doctor if you develop watery or bloody diarrhea, even weeks after finishing the antibiotic.

⚠️ Rare Side Effects

Photosensitivity
Avoid sun exposure and use sunscreen. If you notice a skin reaction, consult your doctor.
QT prolongation
Inform your doctor if you have a history of heart rhythm problems. Seek medical attention if you feel faint or have palpitations.
Hepatotoxicity
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Antacids Major
Warfarin Major
Theophylline Major
NSAIDs Major
Corticosteroids Major
Caffeine Moderate
Cyclosporine Moderate
Probenecid Moderate
Oral hypoglycemics Moderate
Iron supplements Minor

🚨 Major Interactions

  • Antacids, sucralfate, iron, zinc
  • Warfarin
  • Theophylline
  • NSAIDs
  • Corticosteroids

⚡ Moderate Interactions

  • Caffeine
  • Cyclosporine
  • Probenecid
  • Oral hypoglycemics

🍷 Alcohol Interaction

Alcohol may increase the risk of central nervous system side effects such as dizziness, drowsiness, and confusion. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to ofloxacin or other fluoroquinolones","Myasthenia gravis","Pregnancy and breastfeeding (unless clearly needed)","Children under 18 years (except specific indications)","History of tendon disorders with fluoroquinolones"]

⚠️ Warnings & Precautions

["Tendon rupture risk, especially in elderly and those on corticosteroids","Peripheral neuropathy may occur","Central nervous system effects including seizures","May exacerbate myasthenia gravis","Photosensitivity reactions","QT prolongation risk","Clostridium difficile-associated diarrhea","Avoid in patients with known QT prolongation","Use with caution in renal impairment","May affect blood glucose levels in diabetics"]

🤱 Lactation Safety

Ofloxacin is excreted in breast milk. It is not recommended during breastfeeding unless clearly needed. Consult your doctor.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, dizziness, and seizures. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Complete the full course to prevent the infection from returning and to reduce the risk of antibiotic resistance. Take the tablet with a full glass of water, with or without food. Avoid taking antacids, iron, or zinc supplements within 2 hours before or after this medicine, as they can reduce its absorption. Do not consume alcohol while taking this medicine, as it may increase the risk of central nervous system side effects. Inform your doctor if you have kidney or liver problems, diabetes, or a history of tendon disorders. Avoid excessive sun exposure and use sunscreen, as this medicine can make your skin more sensitive to sunlight. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, kidney problems, and CNS effects. Dose adjustment may be needed based on renal function. Use with caution.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is not recommended during pregnancy unless clearly needed.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before surgery. It may interact with other medications used during surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with antibiotics prescribed after dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help flush out bacteria.
🥗
Maintain good hygiene to prevent infections.
😴
Include probiotic-rich foods like yogurt in your diet to support gut health.
💧
Get adequate rest to help your body fight the infection.
🧘
Avoid excessive sun exposure and use sunscreen.
🌞
Practice safe sex to prevent sexually transmitted infections.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture. Gentle activities like walking are usually safe.

🥗 Diet Recommendations

Drink plenty of water.
Include probiotic-rich foods like yogurt.
Avoid dairy products within 2 hours of taking this medicine.
Limit caffeine intake.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities with caution.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of antibiotic resistance, tendon problems, and peripheral neuropathy. It should only be used for the prescribed duration. Regular monitoring of kidney and liver function may be required if used for prolonged periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotic supplements

Can help restore gut flora during and after antibiotic therapy.

Evidence: Well-established
Increased fluid intake

Helps flush out bacteria from the urinary tract.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the effectiveness of live bacterial vaccines like typhoid vaccine. Consult your doctor about vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a UTI. She took it twice daily with food and completed the 7-day course. Her symptoms improved within 3 days, and she experienced only mild nausea that went away after taking it with meals.
💡 Lesson: Taking the medicine with food can reduce stomach upset, and completing the full course prevents recurrence.
👤 A 60-year-old man with a respiratory tract infection
He was prescribed this medicine for bronchitis. He was also taking antacids for acidity. His doctor advised him to take the antacid at least 2 hours after the antibiotic. He recovered well without any complications.
💡 Lesson: Separating antacids from this medicine ensures proper absorption and effectiveness.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for zantof lb 200mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the flu.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: I can stop taking this medicine once I feel better.
    Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe to take with antacids.
    Fact: Antacids can reduce the absorption of this medicine. Take it at least 2 hours before or after antacids.

🔄 Alternative Options

Generic Alternatives

  • Ofloxacin 200mg + Lactobacillus 60 million spores tablet

📊 Comparison with Similar Medicines

[{"medicine":"Ofloxacin 200mg + Lactobacillus","class":"Fluoroquinolone + probiotic","uses":"Bacterial infections","notes":"Combination may reduce antibiotic-associated diarrhea."},{"medicine":"Ofloxacin 200mg alone","class":"Fluoroquinolone","uses":"Bacterial infections","notes":"No probiotic component."},{"medicine":"Ciprofloxacin 500mg","class":"Fluoroquinolone","uses":"Bacterial infections","notes":"Similar spectrum, different dosing."}]

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