Adplatin 50mg Injection (Oxaliplatin): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Fever, chills, or signs of infection
- Unusual bleeding or bruising
- Severe or persistent vomiting or diarrhea
- Chest tightness, rash, or difficulty breathing during or after infusion
- New or worsening numbness, weakness, or difficulty with daily tasks
- Reduced urine output or swelling
- Yellowing of skin or eyes
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is xtide 50mg injection used for?
This medicine is a platinum-based chemotherapy injection containing oxaliplatin 50 mg. It is given intravenously by oncology professionals to treat colorectal cancer and some other cancers. It works by damaging cancer cell DNA and must be used under close medical supervision.
- Generic Name: Oxaliplatin (50mg)
- Manufacturer: Biocon
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 xtide 50mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा ऑक्सालिप्लाटिन 50 मिलीग्राम इंजेक्शन के रूप में उपलब्ध है और इसे कीमोथेरेपी के लिए अस्पताल या कैंसर डे-केयर सेंटर में नस के माध्यम से दिया जाता है। इसका उपयोग मुख्य रूप से कोलोरेक्टल कैंसर, पेट के कैंसर और कुछ अन्य कैंसर के इलाज में किया जाता है। यह कैंसर कोशिकाओं के डीएनए को नुकसान पहुंचाकर उनकी वृद्धि को रोकती है। यह दवा केवल कैंसर विशेषज्ञ की देखरेख में ही दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, कब्ज, थकान, भूख में कमी, मुंह के छाले और खून की कोशिकाओं की कमी शामिल हैं। ठंडी चीजों के संपर्क में आने पर हाथ-पैरों में झुनझुनी, सुन्नपन या गले में तकलीफ हो सकती है। गंभीर दुष्प्रभावों में बुखार के साथ संक्रमण, लगातार बढ़ती नसों की समस्या, सांस लेने में तकलीफ और किडनी या लीवर की समस्या शामिल हो सकती है। कोई भी नई या बढ़ती समस्या होने पर तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल प्रशिक्षित कैंसर विशेषज्ञ द्वारा अस्पताल या डे-केयर सेंटर में ही दी जानी चाहिए। इसे घर पर स्वयं न लगाएं। इंजेक्शन के कुछ दिनों तक ठंडे पेय, बर्फ और ठंडे संपर्क से बचें। बुखार, कंपकंपी, असामान्य रक्तस्राव, लगातार उल्टी या दस्त, और हाथ-पैरों में सुन्नपन होने पर तुरंत डॉक्टर से संपर्क करें। नियमित रूप से खून, किडनी और लीवर की जांच करवाएं। इलाज के दौरान गर्भधारण से बचें और डॉक्टर की सलाह का पालन करें।
💊 xtide 50mg injection Uses & Benefits
[{"condition":"Stage III colon cancer after surgery","description":"This medicine is used as adjuvant chemotherapy, often combined with other agents, to reduce the risk of cancer returning after surgical removal of the tumour.","evidence":"Well-established"},{"condition":"Metastatic colorectal cancer","description":"This medicine is used in combination regimens for advanced or metastatic colorectal cancer to shrink tumours and control disease progression.","evidence":"Well-established"},{"condition":"Advanced gastric and gastroesophageal junction cancer","description":"This medicine may be used in some chemotherapy combinations for advanced stomach and food-pipe cancers under specialist supervision.","evidence":"Moderate"},{"condition":"Pancreatic cancer","description":"This medicine is included in some combination regimens for selected patients with advanced pancreatic cancer.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Ovarian cancer","description":"This medicine has been used in some specialist regimens for selected ovarian cancer patients, but it is not a standard first-choice treatment.","evidence":"Limited"},{"condition":"Lymphoma","description":"This medicine has been studied in certain lymphoma subtypes in specialist settings, but evidence is not strong enough for routine use.","evidence":"Limited"}]
Primary treatment for: Colorectal cancer
Also treats: Gastric cancer, Gastroesophageal junction cancer, Pancreatic cancer
📋 Drug Information
| Generic Name(s) | Oxaliplatin (50mg) |
| Brand Name | xtide 50mg injection |
| Manufacturer | Biocon |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Platinum compounds-Anticancer |
| Route of Administration | Parenteral (intravenous infusion) |
| Storage | Store this medicine in its original packaging in a refrigerator at 2 to 8 degrees Celsius, protected from light. Do not freeze. Follow the storage instructions provided by the manufacturer and the hospital pharmacy. |
| Shelf Life | The shelf life is as printed on the product label and is usually 24 to 36 months from the date of manufacture when stored under recommended conditions. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works after its active ingredient, oxaliplatin, enters cells and undergoes chemical conversion into reactive platinum species. These reactive species bind to DNA and form cross-links between DNA strands, especially between guanine bases. The cross-linked DNA cannot separate properly during replication and transcription, which blocks cancer cell division and triggers programmed cell death. Because cancer cells divide faster than most normal cells, they are more vulnerable to this DNA damage, although normal tissues with rapid turnover can also be affected.
Mechanism Steps
💡 How to Take xtide 50mg injection
Strength: Injection, 50 mg
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified oncologist based on the type and stage of cancer, the treatment regimen, body surface area, blood counts, kidney function, liver function, and previous side effects. It is usually given as an intravenous infusion over a period of hours in a hospital or day-care setting, often once every two to three weeks as part of a combination regimen. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatric oncologist. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially nerve-related effects and low blood counts. The dose and monitoring plan must be individualized by the treating oncologist based on overall health, kidney function, and other medicines being taken. |
| Renal Impairment | This medicine is excreted mainly through the kidneys, so patients with kidney impairment may need dose reduction or closer monitoring. The exact dose adjustment must be determined by the treating oncologist based on kidney function tests. |
| Hepatic Impairment | Patients with significant liver impairment may need closer monitoring and possible dose adjustment. The treating oncologist will decide the appropriate dose based on liver function tests and overall clinical status. |
| Maximum Daily Dose | The maximum dose is not fixed and depends on the treatment protocol, body surface area, and clinical status. It must be determined by the treating oncologist. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of xtide 50mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Aminoglycosides | Major | |
| Live vaccines | Major | |
| Clozapine | Moderate | |
| Phenytoin | Moderate | |
| Amphotericin B | Moderate | |
| Cisplatin | Moderate | |
| Loop diuretics | Moderate | |
| Herbal supplements | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Other nephrotoxic medicines such as aminoglycosides or amphotericin B
- Live vaccines
- Warfarin and other anticoagulants
⚡ Moderate Interactions
- Clozapine
- Phenytoin
- Nephrotoxic or ototoxic antibiotics
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine because it can worsen nausea, dehydration, and liver stress, and may increase the risk of stomach and nerve-related side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe hypersensitivity to oxaliplatin or other platinum compounds","Severe bone marrow suppression","Significant kidney impairment","Active severe infection","Pregnancy and breastfeeding","Severe peripheral neuropathy"]
⚠️ Warnings & Precautions
["This medicine must only be given by trained oncology professionals.","Avoid cold exposure and cold drinks for a few days after each dose if you experience cold-related symptoms.","Report fever, chills, unusual bleeding, or bruising immediately.","Regular blood tests are needed to monitor blood counts, kidney function, and liver function.","Use effective contraception during treatment and for a period advised by your doctor.","Inform your doctor about all other medicines, supplements, and herbal products you take.","Do not receive live vaccines during treatment without approval from your oncologist."]
🤱 Lactation Safety
Breastfeeding is not recommended during treatment with this medicine because it may pass into breast milk and harm the infant. Discuss safe feeding options with your doctor.
💊 Overdose Management
Overdose with this medicine can cause severe bone marrow suppression, nerve toxicity, and other serious effects. Treatment is supportive and must be given in a hospital setting with close monitoring of blood counts, kidney function, and neurological status. There is no specific antidote, so management focuses on treating symptoms and complications.
⏰ Missed Dose
This medicine is given by a healthcare professional in a hospital or day-care setting, so missed doses are managed by the treating oncology team. If an appointment is missed, contact the cancer centre as soon as possible to reschedule. Do not attempt to self-administer this medicine.
Additional Safety Advice
This medicine must only be given by a qualified oncology professional in a properly equipped facility. Do not attempt to self-administer this injection. Inform your doctor about all medicines, supplements, and herbal products you take before starting treatment. Avoid cold drinks, ice, and cold exposure for a few days after each dose if you experience cold-related tingling or throat discomfort. Use warm fluids and keep hands and feet covered in cold weather. Report fever, chills, unusual bleeding or bruising, persistent vomiting, diarrhea, numbness, or difficulty with daily tasks immediately. Regular blood tests are needed to check blood counts, kidney function, and liver function. Use effective contraception during treatment and for a period advised by your doctor. This medicine may harm a developing baby, so pregnancy should be avoided during treatment.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially nerve-related effects, low blood counts, and fatigue. Close monitoring and individualized dose adjustment are important.
🤰 Pregnancy Planning (TTC)
This medicine can harm a developing baby. Women of childbearing age should use effective contraception during treatment and for a period advised by their doctor. Men should also use contraception during and after treatment as advised. Discuss pregnancy planning with your oncologist before starting treatment.
🏥 Post-Surgery Considerations
This medicine is often used after surgery for colon cancer as adjuvant treatment. Your oncology team will decide the timing of treatment based on your recovery from surgery and overall health.
🦷 Dental Procedures
Inform your dentist that you are receiving this medicine before any dental procedure. Low blood counts and mouth sores may increase the risk of bleeding or infection, so your oncology team should be consulted before dental work.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Light activity such as walking may help with fatigue, but avoid activities that could cause injury if you have numbness, tingling, or balance problems. Discuss an appropriate exercise plan with your oncology team.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or day-care setting, so you will need time off for infusions and recovery. Fatigue, nausea, and nerve symptoms may affect your ability to work or drive. Discuss your work schedule and safety-sensitive tasks with your oncology team.
🛑 When to Stop This Medicine
Do not stop or change your treatment schedule on your own. Your oncologist will decide when to stop or modify treatment based on your response, side effects, and overall health. Contact your doctor immediately if you develop severe side effects.
📅 Long-Term Use Effects
Long-term effects of this medicine may include persistent peripheral neuropathy with numbness or tingling in the hands and feet, which can affect daily activities. Some patients may experience ongoing fatigue or changes in kidney function. Regular follow-up with your oncology team is important to monitor for late effects and to adjust treatment as needed.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the cancer type and stage, other chemotherapy combinations may be considered by your oncologist.
Evidence: Well-establishedSome patients may be suitable for targeted or immunotherapy medicines based on tumour testing.
Evidence: Moderate to well-established depending on the cancer type💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Live vaccines should be avoided during treatment with this medicine because the immune system may be suppressed. Inactivated vaccines may be given based on your doctor's advice. Discuss all vaccinations with your oncology team.
📦 Storage Guide
✅ DO
Store in a refrigerator at 2 to 8 degrees Celsius
❌ DON'T
Do not freeze
✅ DO
Keep in original packaging and protect from light
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Follow hospital pharmacy instructions
❌ DON'T
Do not store at room temperature for long periods unless instructed
✈️ Traveling with This Medicine
If you need to travel during treatment, carry this medicine only if your oncology team has approved it and provided proper storage instructions. In general, this medicine is stored in a refrigerator at 2 to 8 degrees Celsius and must not be frozen. Carry a copy of your prescription and treatment summary. For air travel, check airline and customs rules for carrying injectable medicines and keep them in original packaging with a doctor's letter. Plan travel around your treatment schedule and ensure you have access to a hospital in case of side effects.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine is given as an intravenous infusion by a trained healthcare professional in a hospital or day-care setting.
A: The infusion duration is decided by your oncology team and may take a few hours depending on the regimen.
A: Common side effects include nausea, fatigue, low blood counts, and cold-related tingling or numbness in the hands and throat.
A: Many patients are advised to avoid cold drinks and ice for a few days after each dose because cold can trigger tingling and throat discomfort.
A: Yes, regular blood tests are needed to check blood counts, kidney function, and liver function during treatment.
🤔 Common Patient Concerns
🔄 Substitutes for xtide 50mg injection
View AllAlternative brands with exact same active ingredient:
-
oxyrea 50 injectionNeon Laboratories Ltd ₹824.00 56% CHEAPER
-
oxichemo 50mg injectionLupin Ltd ₹937.50 49.9% CHEAPER
-
metaplatin 50mg injectionParenteral Drugs India Ltd ₹1,190.47 36.4% CHEAPER
-
oxoplan 50mg injectionSamarth Life Sciences Pvt Ltd ₹1,239.00 33.8% CHEAPER
-
oxaltor 50mg injectionTorrent Pharmaceuticals Ltd ₹1,369.04 26.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken as a tablet at home.
Fact: This medicine is an injection that must be given by a trained healthcare professional in a hospital or day-care setting. - Myth: Cold drinks are safe during treatment.
Fact: Cold drinks and cold exposure can trigger tingling and throat discomfort in many patients, so they are often avoided for a few days after each dose. - Myth: This medicine has no serious side effects.
Fact: This medicine can cause serious side effects such as low blood counts, nerve damage, and infusion reactions, so close monitoring is required.
🔄 Alternative Options
Generic Alternatives
- Oxaliplatin 50 mg injection
Brand Alternatives
- Adplatin 50mg injection