S Cof Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in sputum or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- High fever with chills
If experiencing severe symptoms, call emergency services immediately.
What is xpen x syrup used for?
This medicine is a combination cough syrup containing Ambroxol 15 mg and Menthol 1 mg per 5 mL. It is used to treat productive cough by thinning mucus and soothing the throat. It is not for dry cough. Take as prescribed by your doctor.
- Generic Name: Ambroxol (15mg) + Menthol (1mg)
- Manufacturer: Penta Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 xpen x syrup के बारे में (Hindi Summary)
उपयोग: यह दवा एम्ब्रोक्सोल 15 मिलीग्राम और मेंथॉल 1 मिलीग्राम प्रति 5 मिलीलीटर की एक संयोजन कफ सिरप है। इसका उपयोग बलगम वाली खांसी (गीली खांसी) के इलाज के लिए किया जाता है। यह गाढ़े बलगम को पतला करके बाहर निकालने में मदद करती है और गले की जलन को शांत करती है। यह सूखी खांसी के लिए नहीं है। इसका सेवन डॉक्टर के निर्देशानुसार ही करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हल्की मतली, छाती में जलन, पेट में असुविधा और कभी-कभी उल्टी शामिल हैं। कुछ लोगों को मुंह सूखना या गले में हल्की जलन महसूस हो सकती है। दुर्लभ मामलों में एलर्जी प्रतिक्रिया जैसे त्वचा पर चकत्ते, खुजली या चेहरे, होंठ या गले में सूजन हो सकती है। यदि कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा का सेवन डॉक्टर के बताए अनुसार ही करें। खुराक से अधिक न लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मात्रा मापने के लिए मापने वाला कप या चम्मच का उपयोग करें। बिना डॉक्टर की सलाह के अन्य कफ सिरप के साथ न लें। यदि आपको पेट के अल्सर, लीवर या किडनी की बीमारी है तो डॉक्टर को बताएं। दवा लेने के बाद चक्कर या नींद आने पर वाहन न चलाएं। ठंडी और सूखी जगह पर रखें। बच्चों की पहुंच से दूर रखें।
💊 xpen x syrup Uses & Benefits
[{"condition":"Productive cough (wet cough)","description":"Helps loosen thick mucus and makes it easier to cough out, providing relief in conditions like bronchitis and common cold.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Used as a mucolytic to reduce mucus viscosity and improve airway clearance.","evidence":"Moderate"},{"condition":"Chronic obstructive pulmonary disease (COPD) with mucus hypersecretion","description":"May help in thinning secretions and improving symptoms, but not a primary treatment.","evidence":"Limited"}]
Off-label uses: [{"condition":"Sore throat relief","description":"Menthol provides a soothing effect, but this is not a primary indication.","evidence":"Limited"}]
Primary treatment for: Productive cough
Also treats: Acute bronchitis, Chronic obstructive pulmonary disease (COPD) with mucus hypersecretion
📋 Drug Information
| Generic Name(s) | Ambroxol (15mg) + Menthol (1mg) |
| Brand Name | xpen x syrup |
| Manufacturer | Penta Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Ambroxol increases serous bronchial secretion, reduces mucus viscosity, and stimulates surfactant production, thereby facilitating mucus clearance. Menthol produces a cooling sensation by activating TRPM8 receptors, providing a soothing effect on the throat and possibly reducing cough reflex sensitivity.
Mechanism Steps
💡 How to Take xpen x syrup
Strength: Each 5 mL contains Ambroxol 15 mg and Menthol 1 mg.
Dosage Information
| Adult Dosage | The usual adult dose is 10 mL (2 teaspoons) three times a day. However, the dose may vary depending on the severity of the condition and the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients, but use with caution due to potential reduced hepatic and renal function. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with severe renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with severe hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 30 mL (6 teaspoons) in divided doses for adults. Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of xpen x syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Codeine | Major | |
| Dextromethorphan | Major | |
| Amoxicillin | Moderate | |
| Cefuroxime | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Antitussives (e.g., codeine, dextromethorphan)
⚡ Moderate Interactions
- Antibiotics (e.g., amoxicillin, cefuroxime)
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach upset and drowsiness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Ambroxol, Menthol, or any component of the formulation","Children under 2 years of age","Peptic ulcer disease (relative contraindication)"]
⚠️ Warnings & Precautions
["Do not use for dry, non-productive cough.","Use with caution in patients with peptic ulcer disease.","Use with caution in severe hepatic or renal impairment.","Avoid concurrent use with cough suppressants.","Do not exceed the recommended dose.","Keep out of reach of children.","If symptoms persist beyond 7 days, consult a doctor."]
🤱 Lactation Safety
Ambroxol is excreted in breast milk in small amounts. Menthol may also pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Shake the bottle well before each use. Use a proper measuring cup or spoon to ensure accurate dosing. Avoid taking this medicine with other cough and cold products without consulting a doctor, as they may contain overlapping ingredients. If you have a history of stomach ulcers, liver disease, or kidney disease, inform your doctor before use. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Store in a cool, dry place away from direct sunlight and out of reach of children. Do not use after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to side effects. Use with caution and monitor for stomach upset, dizziness, or allergic reactions. Dose adjustment may be needed based on renal and hepatic function.
🤰 Pregnancy Planning (TTC)
Consult your doctor before using this medicine if you are planning pregnancy or are pregnant. The safety profile in pregnancy is not well established.
🏥 Post-Surgery Considerations
Consult your doctor before using this medicine after surgery, especially if you are on other medications or have underlying conditions.
🦷 Dental Procedures
No specific precautions. Inform your dentist if you are taking this medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have a cough or fever. Light activity like walking may be okay if you feel up to it. Consult your doctor before resuming intense exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause mild drowsiness in some people. If you feel drowsy, avoid driving or operating heavy machinery. Otherwise, it usually does not significantly impact daily activities.
🛑 When to Stop This Medicine
Stop taking this medicine if your cough improves or as advised by your doctor. If you experience any serious side effects, stop immediately and seek medical help. Do not stop abruptly if you have been on long-term therapy without consulting your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is generally not recommended without medical supervision. Prolonged use may mask underlying conditions. If symptoms persist beyond 7 days, consult a doctor. No serious long-term effects have been reported with recommended doses.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and soothe airways.
Evidence: Well-establishedCan help clear nasal congestion and postnasal drip.
Evidence: ModerateSoothes throat and may reduce cough.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interaction with vaccines. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription copy. Store in a cool, dry place away from direct sunlight. If traveling across time zones, continue with your regular dosing schedule as advised by your doctor. Check customs regulations for carrying medicines. Keep it in your carry-on luggage if possible.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ambroxol starts working within 30-60 minutes, but noticeable relief may take a few doses. Menthol provides immediate soothing effect.
A: Yes, it can be taken with antibiotics like amoxicillin, and it may even enhance their concentration in lung tissue. However, consult your doctor.
A: It is not recommended for children under 2 years. For older children, consult a pediatrician for appropriate dosing.
A: No, this medicine is for productive cough. It may not be effective for dry cough.
🤔 Common Patient Concerns
🔄 Substitutes for xpen x syrup
View AllAlternative brands with exact same active ingredient:
-
xalphen syrupAlpic Remedies Ltd ₹30.00 34% CHEAPER
-
amlody syrupMalody Healthcare Ltd ₹34.00 25.2% CHEAPER
-
anacof syrupAnabiosis Medisciences Ltd ₹34.69 23.7% CHEAPER
-
s cof syrupYuventis Pharmaceuticals ₹54.38 19.6% COSTLIER
-
avrax a syrupAventura Healthcare Pvt Ltd ₹67.50 48.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used for any type of cough.
Fact: This medicine is only for productive (wet) cough. It is not effective for dry cough. - Myth: More medicine means faster relief.
Fact: Taking more than the recommended dose can increase side effects and does not provide faster relief. - Myth: It is safe to take with other cough syrups.
Fact: Combining with other cough syrups may lead to overlapping ingredients and increased risk of side effects.
🔄 Alternative Options
Generic Alternatives
- Ambroxol + Menthol syrup (generic)