vomitus 2mg/5ml syrup - Ondansetron (2mg/5ml) medicine

Ondem Syrup: Complete Guide to Uses, Side Effects, and Safety

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🏭 Aptus Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Irregular heartbeat or palpitations
  • Severe dizziness or fainting
  • Agitation, hallucinations, fever, or muscle stiffness
  • Severe rash or blistering of skin
  • Yellowing of eyes or skin

If experiencing severe symptoms, call emergency services immediately.

What is vomitus 2mg/5ml syrup used for?

This medicine is an oral syrup containing ondansetron, used to prevent and treat nausea and vomiting caused by chemotherapy, radiotherapy, or surgery. It works by blocking serotonin receptors in the gut and brain.

  • Generic Name: Ondansetron (2mg/5ml)
  • Manufacturer: Aptus Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 vomitus 2mg/5ml syrup के बारे में (Hindi Summary)

उपयोग: यह दवा ओंडानसेट्रॉन सिरप है, जिसका उपयोग कीमोथेरेपी, रेडियोथेरेपी या सर्जरी के कारण होने वाली मतली और उल्टी को रोकने और इलाज करने के लिए किया जाता है। यह मतली और उल्टी को नियंत्रित करने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, कब्ज, थकान, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, अनियमित दिल की धड़कन या सेरोटोनिन सिंड्रोम हो सकते हैं। किसी भी असामान्य लक्षण पर डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। निर्धारित खुराक से अधिक न लें। यदि आपको चक्कर या नींद आती है तो वाहन चलाने या मशीनरी चलाने से बचें। यदि आपको लीवर की समस्या, दिल की धड़कन की समस्या है या आप अन्य दवाएं ले रहे हैं तो अपने डॉक्टर को बताएं।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 vomitus 2mg/5ml syrup Uses & Benefits

[{"condition":"Chemotherapy-induced nausea and vomiting","description":"Prevents and treats nausea and vomiting caused by cancer chemotherapy.","evidence":"Well-established"},{"condition":"Radiotherapy-induced nausea and vomiting","description":"Helps control nausea and vomiting resulting from radiation therapy.","evidence":"Well-established"},{"condition":"Post-operative nausea and vomiting","description":"Used to prevent and treat nausea and vomiting after surgery.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Hyperemesis gravidarum","description":"Sometimes used off-label for severe nausea and vomiting during pregnancy, but only under strict medical supervision.","evidence":"Limited"},{"condition":"Nausea from gastroenteritis","description":"May be used off-label to relieve nausea associated with viral or bacterial gastroenteritis.","evidence":"Limited"}]

Primary treatment for: Nausea and vomiting

Also treats: Chemotherapy-induced nausea and vomiting, Radiotherapy-induced nausea and vomiting, Post-operative nausea and vomiting

📋 Drug Information

Generic Name(s)Ondansetron (2mg/5ml)
Brand Namevomitus 2mg/5ml syrup
ManufacturerAptus Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action ClassSerotonin antagonists (5-HT3 antagonists)
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine exactly as prescribed by your doctor.
2
Shake the bottle well before measuring the dose.
3
Use the provided measuring cup or syringe for accurate dosing.
4
Avoid driving or operating machinery if you feel drowsy.
5
Inform your doctor if you have liver or heart problems.
6
Do not use this medicine for longer than prescribed without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Nausea and vomiting after chemotherapy
This medicine is commonly prescribed for this.
Likely Use
Nausea after surgery
This medicine is used to prevent and treat post-operative nausea.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed after oral administration, with peak plasma concentrations typically reached within 1.5 to 2 hours.
DistributionThis medicine is widely distributed throughout the body, including the gastrointestinal tract and the central nervous system.
Protein BindingApproximately 70% to 76% of this medicine is bound to plasma proteins.
MetabolismThis medicine is extensively metabolized in the liver by multiple cytochrome P450 enzymes, including CYP3A4, CYP2D6, and CYP1A2.
Half-LifeThe elimination half-life of this medicine is approximately 3 to 6 hours in healthy adults.
ExcretionThis medicine and its metabolites are primarily excreted in the urine and to a lesser extent in the feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 60% due to first-pass metabolism.
Onset of ActionThis medicine typically begins to relieve nausea within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations of this medicine are reached approximately 1.5 to 2 hours after oral administration.
Duration of ActionThe antiemetic effect of this medicine lasts for approximately 4 to 8 hours after a single oral dose.

How It Works

This medicine works by selectively blocking serotonin 5-HT3 receptors located on vagal nerve terminals in the gastrointestinal tract and in the chemoreceptor trigger zone of the brain. By blocking these receptors, it prevents serotonin from activating the vomiting reflex, thereby reducing nausea and vomiting.

Mechanism Steps

1
Receptor binding: This medicine binds to serotonin 5-HT3 receptors on vagal afferent nerves in the gut and in the brain's chemoreceptor trigger zone.
2
Blockade of serotonin signals: By occupying these receptors, it prevents serotonin released during chemotherapy, radiotherapy, or surgery from activating the vomiting center.
3
Inhibition of vomiting reflex: The blockade reduces the transmission of emetic signals to the vomiting center in the medulla, thereby preventing nausea and vomiting.

💡 How to Take vomitus 2mg/5ml syrup

Strength: Ondansetron 2mg/5ml oral syrup

1Shake the bottle well before each use.
2Measure the dose accurately using the provided measuring cup or syringe.
3Take this medicine orally, with or without food.
4Follow your doctor's instructions regarding the timing and duration of treatment.
5Do not exceed the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine for prevention of chemotherapy-induced nausea and vomiting is 8 mg taken orally 30 minutes before chemotherapy, followed by 8 mg every 12 hours for up to 2 days. For post-operative nausea and vomiting, 16 mg is given orally 1 hour before surgery. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine. Dose adjustment may be necessary based on liver and kidney function. Consult a doctor for appropriate dosing.
Renal ImpairmentNo dose adjustment is typically required for mild to moderate renal impairment. For severe renal impairment, consult a doctor.
Hepatic ImpairmentFor patients with severe liver impairment, the maximum daily dose should not exceed 8 mg. Consult a doctor for appropriate dosing.
Maximum Daily DoseThe maximum recommended daily dose of this medicine is 24 mg for adults. For patients with severe liver impairment, the maximum daily dose is 8 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit juice
Avoid
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of vomitus 2mg/5ml syrup

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Constipation (Common (5-10%))
Increase fluid and fiber intake. Consult doctor if it persists.
Fatigue (Common (5-10%))
Rest and avoid driving if you feel tired. Consult doctor if it interferes with daily activities.
Dizziness (Common (5-10%))
Avoid sudden movements. Do not drive or operate machinery if dizzy.
Drowsiness (Common (5-10%))
Avoid alcohol and activities requiring alertness. Consult doctor if it persists.

🚨 Serious Side Effects

Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling, or difficulty breathing.
Irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention if you feel palpitations, chest pain, or shortness of breath.
Serotonin syndrome (Rare (<0.1%))
Seek immediate medical attention if you have agitation, hallucinations, fever, fast heart rate, or muscle stiffness.

⚠️ Rare Side Effects

QT prolongation
Consult doctor if you have a history of heart rhythm problems. Regular ECG monitoring may be needed.
Severe skin reactions
Seek immediate medical attention if you develop a severe rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Apomorphine Major
Amiodarone Major
Tramadol Moderate
Fluoxetine Moderate
Carbamazepine Minor
Rifampicin Minor

🚨 Major Interactions

  • Apomorphine
  • Amiodarone

⚡ Moderate Interactions

  • Tramadol
  • SSRIs (e.g., fluoxetine)

🍷 Alcohol Interaction

Alcohol may increase drowsiness and dizziness caused by this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to ondansetron or any component of this medicine","Concurrent use with apomorphine"]

⚠️ Warnings & Precautions

["Use with caution in patients with severe liver impairment.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with heart rhythm disorders or those taking other QT-prolonging drugs.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Do not use this medicine for longer than prescribed without medical advice."]

🤱 Lactation Safety

This medicine may pass into breast milk. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include severe drowsiness, dizziness, irregular heartbeat, and fainting. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid driving or operating heavy machinery if you feel dizzy or drowsy after taking this medicine. Inform your doctor if you have liver problems, heart rhythm disorders, or if you are taking other medications. Do not use this medicine for longer than prescribed without medical advice.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Dose adjustment may be necessary based on liver and kidney function.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before using this medicine. It should be used during pregnancy only if clearly needed.

🏥 Post-Surgery Considerations

This medicine is often used to prevent and treat nausea and vomiting after surgery. Follow your doctor's instructions for dosing.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated to prevent dehydration from vomiting.
🥗
Eat small, frequent meals to reduce nausea.
😴
Avoid strong odors that may trigger nausea.
💧
Get plenty of rest.
🧘
Practice relaxation techniques to reduce stress.

🏋️ Exercise Considerations

Avoid strenuous exercise if you feel dizzy or fatigued. Light activities like walking may be beneficial, but consult your doctor before starting any exercise routine.

🥗 Diet Recommendations

Eat bland, easy-to-digest foods like crackers and toast.
Avoid spicy, greasy, or heavy meals.
Sip clear fluids frequently.
Avoid alcohol and caffeine.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness or dizziness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience severe side effects, seek medical advice immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended without medical supervision. Prolonged use may increase the risk of side effects such as constipation, headache, and cardiac arrhythmias. Regular monitoring may be required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Ginger

May help reduce nausea, but evidence is limited.

Evidence: Limited
Acupuncture

Some studies suggest it may help with nausea, but more research is needed.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from direct sunlight. If traveling across time zones, adjust dosing times as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old woman undergoing chemotherapy
She was prescribed this medicine before her chemotherapy sessions. She found that taking it 30 minutes before treatment significantly reduced her nausea and allowed her to eat normally. She emphasized the importance of taking it exactly as directed.
💡 Lesson: Taking this medicine before chemotherapy can greatly reduce nausea and improve quality of life.
👤 A 60-year-old man after surgery
He experienced severe nausea after surgery. His doctor prescribed this medicine, and within an hour, his nausea subsided. He was advised to avoid driving for 24 hours due to drowsiness.
💡 Lesson: This medicine is effective for post-operative nausea, but caution is needed with activities requiring alertness.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts working within 30 to 60 minutes after oral administration.

Q: Can I take this medicine with other medications?

A: Inform your doctor about all medications you are taking, as this medicine can interact with some drugs.

Q: Is it safe to take during pregnancy?

A: Consult your doctor before using this medicine during pregnancy. It should be used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for vomitus 2mg/5ml syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure all types of nausea.
    Fact: This medicine is specifically effective for nausea and vomiting caused by chemotherapy, radiotherapy, and surgery. It may not be effective for other causes.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription drug and should only be used under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Ondansetron oral syrup

Brand Alternatives

  • Emeset
  • Vomikind
  • Ondem

📊 Comparison with Similar Medicines

[{"medicine":"Ondansetron","class":"5-HT3 antagonist","route":"Oral","common_use":"Chemotherapy-induced nausea"},{"medicine":"Granisetron","class":"5-HT3 antagonist","route":"Oral","common_use":"Chemotherapy-induced nausea"},{"medicine":"Metoclopramide","class":"Dopamine antagonist","route":"Oral","common_use":"Gastroparesis, nausea"}]

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