venpres-m 50 tablet er - Telmisartan (40mg) + Metoprolol Succinate (50mg) medicine

Embeta-TM 50 Tablet ER: Comprehensive Medicine Guide

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🏭 Leeford Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
🤰 Pregnancy Category Not recommended. This medicine is contraindicated in pregnancy due to potential harm to the fetus, especially in the second and third trimesters. Alternative treatments should be considered. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Very slow heart rate (below 50 beats per minute)
  • Difficulty breathing or wheezing
  • Swelling of face, lips, tongue, or throat
  • Chest pain or worsening angina
  • Yellowing of skin or eyes (jaundice)
  • Decreased urine output or swelling in legs

If experiencing severe symptoms, call emergency services immediately.

What is venpres-m 50 tablet er used for?

This medicine is a combination of Telmisartan 40 mg and Metoprolol Succinate 50 mg used to treat high blood pressure. It works by relaxing blood vessels and slowing the heart rate. It is taken once daily orally, usually in the morning. Do not stop it abruptly without consulting your doctor.

  • Generic Name: Telmisartan (40mg) + Metoprolol Succinate (50mg)
  • Manufacturer: Leeford Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 venpres-m 50 tablet er के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें टेल्मिसार्टन और मेटोप्रोलोल सक्सिनेट दो सक्रिय तत्व हैं जो मिलकर रक्तचाप को कम करते हैं। यह दवा रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके काम करती है। इसे आमतौर पर दिन में एक बार मुँह से लिया जाता है। इस दवा का सेवन डॉक्टर के निर्देशानुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द और हृदय गति का धीमा होना शामिल है। कुछ लोगों को ठंड लगना, मतली या पेट में परेशानी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, या बेहोशी हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें क्योंकि इससे एनजाइना या दिल का दौरा पड़ सकता है। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। यदि आपको अस्थमा, मधुमेह, जिगर या गुर्दे की बीमारी है तो डॉक्टर को बताएं। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 venpres-m 50 tablet er Uses & Benefits

  • [{"condition":"Essential Hypertension","description":"This medicine is used to lower blood pressure in patients whose hypertension is not controlled by monotherapy.
  • The combination provides complementary mechanisms for blood pressure reduction.","evidence":"Well-established"},{"condition":"Hypertension with High Cardiovascular Risk","description":"May be used in patients with hypertension and additional cardiovascular risk factors, such as diabetes or coronary artery disease, to reduce the risk of cardiovascular events.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Heart Failure with Reduced Ejection Fraction","description":"Metoprolol succinate is approved for heart failure, but the combination with telmisartan may be used off-label in some patients with heart failure and hypertension.","evidence":"Limited"},{"condition":"Angina Pectoris","description":"Metoprolol is used for angina, and telmisartan may provide additional blood pressure control. The combination may be used off-label for angina with hypertension.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Coronary artery disease, Heart failure with reduced ejection fraction, Angina pectoris, Diabetic nephropathy

📋 Drug Information

Generic Name(s)Telmisartan (40mg) + Metoprolol Succinate (50mg)
Brand Namevenpres-m 50 tablet er
ManufacturerLeeford Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning.
2
Monitor your blood pressure and heart rate regularly at home.
3
Do not stop this medicine abruptly without consulting your doctor.
4
Avoid alcohol while taking this medicine to prevent dizziness and low blood pressure.
5
Inform your doctor if you have asthma, diabetes, or kidney problems.
6
Report any unusual symptoms like severe dizziness, fainting, or swelling to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood pressure
This medicine is commonly prescribed for hypertension.
Likely Use
Chest pain (angina)
May be used in patients with angina and hypertension.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
This medicine is not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTelmisartan is rapidly absorbed after oral administration, with peak plasma concentrations reached within 0.5 to 1 hour. Metoprolol succinate is absorbed throughout the gastrointestinal tract, and the extended-release formulation provides sustained plasma levels. Food does not significantly affect the absorption of telmisartan, but metoprolol absorption may be slightly increased when taken with food.
DistributionTelmisartan is highly bound to plasma proteins and has a large volume of distribution. Metoprolol is moderately bound to plasma proteins and distributes widely into tissues, including the heart, lungs, and liver.
Protein BindingTelmisartan: >99.5% bound to plasma proteins; Metoprolol: approximately 12% bound to plasma proteins.
MetabolismTelmisartan is metabolized primarily by conjugation with glucuronic acid, with minimal cytochrome P450 involvement. Metoprolol is extensively metabolized in the liver, primarily by CYP2D6, to inactive metabolites.
Half-LifeTelmisartan: approximately 24 hours; Metoprolol: 3 to 7 hours.
ExcretionTelmisartan is excreted mainly in the feces via bile, with less than 1% excreted unchanged in urine. Metoprolol is excreted primarily in the urine as metabolites.
BioavailabilityTelmisartan: approximately 42% after oral administration; Metoprolol succinate: approximately 77% after oral administration.
Onset of ActionAntihypertensive effect begins within 1 to 2 hours after oral administration, with maximum effect achieved after several weeks of therapy.
Peak Plasma TimeTelmisartan: 0.5 to 1 hour; Metoprolol succinate: 3 to 7 hours (extended-release).
Duration of ActionBlood pressure-lowering effect lasts for 24 hours, allowing once-daily dosing.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release, which lowers blood pressure. Metoprolol succinate is a cardioselective beta-1 adrenergic receptor blocker that reduces heart rate, myocardial contractility, and cardiac output, and also suppresses renin release from the kidneys. Together, they reduce blood pressure through vasodilation and reduced cardiac workload.

Mechanism Steps

1
Telmisartan blocks AT1 receptors: Telmisartan binds to angiotensin II type 1 receptors in vascular smooth muscle and other tissues, preventing angiotensin II from exerting its vasoconstrictor and aldosterone-stimulating effects.
2
Reduced vasoconstriction and aldosterone: Blockade of AT1 receptors leads to vasodilation and decreased aldosterone secretion, which reduces sodium and water retention, further lowering blood pressure.
3
Metoprolol blocks beta-1 receptors: Metoprolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output.
4
Suppression of renin release: Beta-1 blockade in the kidneys reduces renin release, leading to decreased angiotensin II production and further blood pressure reduction.
5
Combined antihypertensive effect: The complementary actions of telmisartan and metoprolol result in a more pronounced and sustained reduction in blood pressure than either agent alone.

💡 How to Take venpres-m 50 tablet er

Strength: Telmisartan 40 mg and Metoprolol Succinate 50 mg extended-release tablet.

1Take this medicine at the same time each day, preferably in the morning.
2Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet.
3You may take it with or without food, but taking it with food may reduce stomach upset.
4Do not stop taking this medicine abruptly without consulting your doctor.
5If you miss a dose, follow the missed dose instructions.
6Store the medicine as directed and keep it out of reach of children.

Dosage Information

Adult DosageThe usual adult dose is one tablet of Telmisartan 40 mg and Metoprolol Succinate 50 mg taken orally once daily, with or without food. The dose may be adjusted by the clinician based on blood pressure response and tolerability. The maximum recommended dose is Telmisartan 80 mg and Metoprolol Succinate 100 mg once daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, particularly bradycardia and hypotension. Start with a lower dose and titrate slowly. Monitor renal function and heart rate regularly.
Renal ImpairmentNo dosage adjustment is required for mild to moderate renal impairment. In severe renal impairment (eGFR <30 mL/min), use with caution and monitor renal function and potassium levels. Metoprolol is excreted renally, so dose adjustment may be needed.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. In severe hepatic impairment, the combination is contraindicated. Telmisartan and metoprolol are both metabolized in the liver; dose reduction may be necessary.
Maximum Daily DoseTelmisartan 80 mg and Metoprolol Succinate 100 mg once daily.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Grapefruit juice
Avoid
May increase metoprolol levels and risk of side effects.
High-potassium foods
Moderate intake
Telmisartan may increase potassium levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of venpres-m 50 tablet er

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid driving if dizzy. Consult doctor if persistent.
Fatigue (Common (5-10%))
Ensure adequate rest. If fatigue interferes with daily activities, consult your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if severe or persistent.
Bradycardia (slow heart rate) (Common (5-10%))
Monitor pulse. If heart rate falls below 50 beats per minute or you feel faint, contact your doctor.
Cold extremities (Common (5-10%))
Keep hands and feet warm. Consult doctor if severe or associated with pain.

🚨 Serious Side Effects

Severe bradycardia or heart block (Rare (<0.1%))
Seek immediate medical attention if you experience fainting, severe dizziness, or a very slow pulse.
Angioedema (Rare (<0.1%))
Seek emergency care if you develop swelling of the face, lips, tongue, or throat, or difficulty breathing.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you experience wheezing, chest tightness, or difficulty breathing.
Worsening heart failure (Uncommon (0.1-1%))
Contact your doctor if you experience increased shortness of breath, swelling of ankles, or sudden weight gain.
Severe hypotension (Rare (<0.1%))
Lie down and seek medical help if you feel faint or have very low blood pressure.

⚠️ Rare Side Effects

Depression
Consult your doctor if you experience persistent sadness or loss of interest.
Memory impairment
Discuss with your doctor if you notice cognitive changes.
Psoriasis-like rash
Consult a dermatologist; may require discontinuation.
Hepatitis
Seek medical attention if you develop jaundice, dark urine, or abdominal pain.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Spironolactone Major
Ibuprofen Major
Verapamil Major
Fluoxetine Moderate
Digoxin Moderate
Lithium Moderate
Metformin Moderate
Antacids Minor
Rifampicin Minor
Clonidine Major

🚨 Major Interactions

  • Potassium-sparing diuretics (e.g., spironolactone)
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Verapamil or diltiazem
  • Clonidine
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • Digoxin
  • Lithium
  • Oral hypoglycemics

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effects of this medicine and increase the risk of dizziness, fainting, and slow heart rate. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Heart block greater than first degree","Cardiogenic shock","Decompensated heart failure","Severe hepatic impairment","Pregnancy","Hypersensitivity to telmisartan, metoprolol, or any component","Bilateral renal artery stenosis"]

⚠️ Warnings & Precautions

["Do not stop this medicine abruptly, as it may worsen angina or precipitate a heart attack.","Use with caution in patients with asthma or COPD; metoprolol may cause bronchospasm.","May mask symptoms of hypoglycemia in diabetic patients.","Avoid use in patients with severe liver disease.","Monitor potassium levels, especially when used with potassium-sparing diuretics.","May cause dizziness; avoid driving or operating machinery until effects are known.","Use with caution in patients with peripheral vascular disease.","Not recommended during pregnancy or breastfeeding."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding; alternative medications may be preferred.

💊 Overdose Management

Overdose may cause severe hypotension, bradycardia, heart failure, bronchospasm, and hypoglycemia. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Administer intravenous fluids, atropine for bradycardia, and vasopressors for hypotension. Metoprolol overdose may require glucagon or pacemaker insertion. Contact a poison control center immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop or change the dose without consulting your clinician, as abrupt withdrawal of metoprolol can worsen angina or precipitate a heart attack. Avoid alcohol while taking this medicine, as it may enhance the blood pressure-lowering effect and increase dizziness. Inform your doctor if you have asthma, chronic obstructive pulmonary disease, diabetes, liver disease, or kidney disease. Do not use potassium supplements or salt substitutes containing potassium without medical advice. This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. Pregnant women should not take this medicine, and women planning pregnancy should consult their doctor for alternative treatment.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering and heart rate-slowing effects of this medicine. Start with a lower dose and monitor closely for dizziness, falls, and bradycardia. Regular monitoring of renal function and electrolytes is recommended.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy. Women planning pregnancy should consult their doctor to switch to a safer alternative before conception. Effective contraception is advised while taking this medicine.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect heart rate and blood pressure during surgery. Do not stop the medicine without medical advice.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may cause dry mouth or interact with local anesthetics containing epinephrine. Monitor blood pressure and heart rate during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Engage in regular physical activity like walking or swimming.
😴
Reduce salt intake to less than 5 grams per day.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep and maintain a regular sleep schedule.

🏋️ Exercise Considerations

This medicine may cause dizziness or slow heart rate during exercise. Avoid strenuous activities until you know how the medicine affects you. Stay hydrated and avoid overheating. Consult your doctor before starting a new exercise program.

🥗 Diet Recommendations

Follow a heart-healthy diet rich in fruits, vegetables, and whole grains.
Limit sodium intake to help control blood pressure.
Include potassium-rich foods in moderation, but avoid excessive intake.
Reduce saturated and trans fats.
Limit caffeine and avoid energy drinks.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is usually safe to continue desk work, but take breaks if you feel dizzy.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects like severe bradycardia, angioedema, or worsening heart failure, seek immediate medical attention. Your doctor may adjust the dose or switch to an alternative medicine.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups should include blood pressure, heart rate, kidney function, and potassium levels. Prolonged use may increase the risk of new-onset diabetes or worsen glucose tolerance. Do not stop the medicine without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help lower blood pressure and complement medicine.

Evidence: Well-established
Other antihypertensive combinations

Alternative combinations like ARB + calcium channel blocker may be used if this medicine is not tolerated.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, patients with cardiovascular disease should follow routine vaccination schedules, including influenza and pneumococcal vaccines, as advised by their doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Carry enough supply for the entire trip plus extra in case of delays.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with hypertension not controlled on telmisartan alone
He was prescribed this medicine by his cardiologist. After 4 weeks, his blood pressure stabilized and he felt more energetic. He learned to monitor his pulse daily and avoid alcohol. He experienced mild dizziness initially, which resolved after a few days.
💡 Lesson: Combination therapy can be more effective for blood pressure control, but regular monitoring and lifestyle changes are essential.
👤 A 62-year-old woman with hypertension and diabetes
She started this medicine and noticed her blood pressure improved. However, she experienced fatigue and cold hands. Her doctor adjusted the dose and advised her to monitor her blood sugar more frequently because metoprolol can mask hypoglycemia symptoms.
💡 Lesson: Patients with diabetes need careful monitoring when taking beta-blockers, as symptoms of low blood sugar may be masked.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but maximum effect may take several weeks. Continue taking it regularly as prescribed.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause serious problems.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is this medicine safe during pregnancy?

A: No, this medicine is contraindicated during pregnancy. Consult your doctor for alternative treatment if you are pregnant or planning pregnancy.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my diabetes medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for venpres-m 50 tablet er

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause dangerous rebound hypertension or heart problems.
  • Myth: This medicine causes kidney damage.
    Fact: When used appropriately, this medicine can protect kidney function in some patients. Regular monitoring is important.
  • Myth: You can take this medicine with alcohol.
    Fact: Alcohol can enhance the blood pressure-lowering effect and increase dizziness and slow heart rate. It is best avoided.

🔄 Alternative Options

Generic Alternatives

  • Telmisartan 40 mg + Metoprolol Succinate 50 mg generic tablets

Brand Alternatives

  • Embeta-TM 50 Tablet ER
  • Telma-M 50 Tablet ER
  • Telmikind-M 50 Tablet ER

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Telmisartan 40 mg + Metoprolol Succinate 50 mg","frequency":"Once daily","notes":"Combination for hypertension."},{"medicine":"Telmisartan 40 mg alone","composition":"Telmisartan 40 mg","frequency":"Once daily","notes":"ARB monotherapy."},{"medicine":"Metoprolol Succinate 50 mg alone","composition":"Metoprolol Succinate 50 mg","frequency":"Once daily","notes":"Beta-blocker monotherapy."}]

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