davaindia telmisartan+metoprolol succinate 40mg/50mg tablet er - Telmisartan (40mg) + Metoprolol Succinate (50mg) medicine

Arbitel-MT 50 Tablet ER: Complete Medicine Guide

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🏭 Davaindia Generic Pharmacy 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 23, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. Telmisartan is contraindicated in pregnancy due to risk of fetal harm. Metoprolol may be used with caution if benefits outweigh risks, but combination is generally avoided. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination evidence is supportive.
Reviewed by
SaathiMed Expert Panel | Sep 23, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe dizziness or fainting
  • Difficulty breathing or wheezing
  • Chest pain or irregular heartbeat
  • Swelling of face, lips, tongue, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Sudden weight gain or swelling in legs

If experiencing severe symptoms, call emergency services immediately.

What is davaindia telmisartan+metoprolol succinate 40mg/50mg tablet er used for?

This medicine is a combination of Telmisartan and Metoprolol Succinate used to treat high blood pressure. It works by relaxing blood vessels and slowing the heart rate. It is taken once daily orally, usually in the morning. Do not stop suddenly without medical advice.

  • Generic Name: Telmisartan + Metoprolol Succinate
  • Manufacturer: Davaindia Generic Pharmacy
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 davaindia telmisartan+metoprolol succinate 40mg/50mg tablet er के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें टेल्मिसार्टन और मेटोप्रोलोल सक्सिनेट दो सक्रिय तत्व हैं। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। यह उन रोगियों के लिए है जिनका रक्तचाप एक दवा से नियंत्रित नहीं होता। यह दिल के दौरे के बाद और एंजाइना में भी फायदेमंद हो सकती है। इसे डॉक्टर के निर्देशानुसार ही लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, और हृदय गति का धीमा होना शामिल हैं। कुछ रोगियों को ठंडे हाथ-पैर, मतली या दस्त हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर निम्न रक्तचाप, सांस लेने में कठिनाई, या गुर्दे की समस्या शामिल हो सकती है। यदि आपको बेहोशी, गंभीर चक्कर, या सूजन हो तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अचानक बंद न करें। नियमित रूप से रक्तचाप और हृदय गति की जांच करें। शराब से बचें क्योंकि इससे चक्कर आ सकते हैं। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं तो डॉक्टर को बताएं। मधुमेह रोगियों में यह दवा निम्न रक्त शर्करा के लक्षणों को छिपा सकती है। वाहन चलाते समय सावधानी बरतें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 davaindia telmisartan+metoprolol succinate 40mg/50mg tablet er Uses & Benefits

  • [{"condition":"Essential Hypertension","description":"This medicine is used to lower high blood pressure when monotherapy is insufficient.
  • It reduces cardiovascular risk.","evidence":"Well-established"},{"condition":"Stable Angina Pectoris","description":"Metoprolol component helps reduce angina frequency by decreasing myocardial oxygen demand.","evidence":"Well-established"},{"condition":"Post-Myocardial Infarction","description":"Beta-blocker component reduces risk of reinfarction and mortality after a heart attack.","evidence":"Well-established"},{"condition":"Heart Failure (select cases)","description":"Metoprolol succinate is used in stable heart failure to improve survival, but combination with telmisartan may be used cautiously.","evidence":"Well-established for metoprolol; combination evidence limited"}]

Off-label uses: [{"condition":"Migraine Prophylaxis","description":"Beta-blockers like metoprolol are sometimes used off-label to prevent migraines.","evidence":"Limited"},{"condition":"Performance Anxiety","description":"Beta-blockers may be used off-label for situational anxiety, but combination product is not typical.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina, Post-myocardial infarction, Heart failure (stable)

📋 Drug Information

Generic Name(s)Telmisartan + Metoprolol Succinate
Brand NameArbitel-MT 50 Tablet ER
ManufacturerDavaindia Generic Pharmacy
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassAngiotensin II Receptor Blocker (ARB) + Beta-Blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day, preferably in the morning.
2
Monitor your blood pressure and heart rate regularly and keep a log.
3
Do not stop this medicine abruptly without consulting your doctor.
4
Avoid alcohol as it can increase dizziness and low blood pressure.
5
Inform your doctor if you have asthma, diabetes, or kidney problems.
6
Report any unusual symptoms like severe dizziness, fainting, or difficulty breathing immediately.
7
Follow a low-salt diet and regular exercise to enhance the effect of this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood pressure
This medicine is commonly prescribed for this.
Likely Use
Chest pain (angina)
May be used to reduce angina frequency.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary
Headache
Not a primary headache treatment.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTelmisartan is rapidly absorbed after oral administration, with absolute bioavailability of about 42-58%. Metoprolol succinate is completely absorbed but undergoes extensive first-pass metabolism, resulting in about 50% systemic availability. Food does not significantly affect absorption of either component.
DistributionTelmisartan is highly protein-bound (>99.5%) and has a large volume of distribution. Metoprolol is moderately protein-bound (about 12%) and distributes widely, including to the heart, lungs, and liver.
Protein BindingTelmisartan: >99.5%; Metoprolol: ~12%.
MetabolismTelmisartan undergoes minimal metabolism, mostly conjugation to glucuronide. Metoprolol is extensively metabolized in the liver by CYP2D6, with some metabolism by CYP3A4.
Half-LifeTelmisartan: approximately 24 hours; Metoprolol: 3-7 hours.
ExcretionTelmisartan is excreted mainly in feces via bile, with less than 1% in urine. Metoprolol is excreted primarily in urine as metabolites.
BioavailabilityTelmisartan: ~42-58%; Metoprolol succinate: ~50%.
Onset of ActionBlood pressure lowering effect begins within 1-2 hours for telmisartan and within 1-2 hours for metoprolol, but full therapeutic effect may take 1-2 weeks.
Peak Plasma TimeTelmisartan: 0.5-1 hour; Metoprolol: 3-7 hours (succinate formulation).
Duration of ActionTelmisartan: 24 hours; Metoprolol succinate: 24 hours.

How It Works

This medicine combines two antihypertensive agents with complementary mechanisms. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release, thereby lowering blood pressure and reducing sodium retention. Metoprolol succinate is a cardioselective beta-1 blocker that reduces heart rate, myocardial contractility, and cardiac output, and also suppresses renin release. Together, they provide effective blood pressure control and reduce cardiac workload.

Mechanism Steps

1
Telmisartan blocks AT1 receptors: Telmisartan binds to angiotensin II type 1 receptors in vascular smooth muscle and adrenal cortex, preventing angiotensin II-mediated vasoconstriction and aldosterone release.
2
Metoprolol blocks beta-1 receptors: Metoprolol selectively blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and conduction, and also decreases renin release from the kidneys.
3
Combined effect lowers blood pressure: The combined reduction in peripheral resistance (from telmisartan) and cardiac output (from metoprolol) leads to effective blood pressure lowering and reduced cardiac workload.

💡 How to Take davaindia telmisartan+metoprolol succinate 40mg/50mg tablet er

Strength: Tablet containing Telmisartan 40 mg and Metoprolol Succinate 50 mg.

1Take this medicine at the same time each day, preferably in the morning.
2Swallow the tablet whole with a glass of water. Do not crush or chew.
3You can take it with or without food, but taking it with food may reduce stomach upset.
4Do not stop taking this medicine without consulting your doctor.
5If you miss a dose, follow the missed dose instructions.
6Monitor your blood pressure and heart rate regularly.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, preferably in the morning. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and monitor blood pressure and heart rate closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be needed based on creatinine clearance. Monitor renal function regularly.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be needed. Avoid in severe hepatic impairment.
Maximum Daily DoseOne tablet once daily. Do not exceed the prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
Grapefruit juice
Avoid
May increase metoprolol levels.
High-potassium foods
Moderate intake
Telmisartan can increase potassium levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of davaindia telmisartan+metoprolol succinate 40mg/50mg tablet er

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid driving if dizzy.
Fatigue (Common (5-10%))
Usually improves with time. Consult doctor if persistent.
Headache (Common (5-10%))
May resolve on its own. Use acetaminophen if needed, but consult doctor.
Bradycardia (slow heart rate) (Common (5-10%))
Monitor pulse. If below 50 bpm or symptomatic, contact doctor.
Cold extremities (Common (5-10%))
Keep warm. Report if severe or persistent.

🚨 Serious Side Effects

Severe hypotension (Rare (<0.1%))
Seek immediate medical attention if you faint or experience severe dizziness.
Bronchospasm (Rare (<0.1%))
Seek immediate medical attention if you have difficulty breathing, wheezing, or chest tightness.
Worsening heart failure (Rare (<0.1%))
Report sudden weight gain, swelling, or shortness of breath to your doctor immediately.
Acute kidney injury (Rare (<0.1%))
Contact doctor if you notice decreased urine output or swelling.
Angioedema (Very rare (<0.01%))
Seek emergency care if you experience swelling of face, lips, tongue, or throat.

⚠️ Rare Side Effects

Severe liver injury
Report yellowing of skin or eyes, dark urine, or severe abdominal pain.
Severe allergic reactions
Seek emergency care for rash, itching, or swelling.
Depression
Consult doctor if you feel persistently sad or hopeless.
Memory impairment
Discuss with doctor if you notice cognitive changes.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Spironolactone Major
Ibuprofen Major
Fluoxetine Major
Verapamil Major
Lithium Major
Prazosin Moderate
Clonidine Moderate
Insulin Moderate
Rifampin Moderate
Antacids Minor

🚨 Major Interactions

  • Potassium-sparing diuretics (e.g., spironolactone)
  • NSAIDs (e.g., ibuprofen)
  • Lithium
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
  • Verapamil or diltiazem

⚡ Moderate Interactions

  • Alpha-blockers (e.g., prazosin)
  • Clonidine
  • Insulin and oral hypoglycemics
  • Rifampin

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effects of this medicine, leading to dizziness, fainting, or falls. It can also increase the risk of liver problems. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Severe hepatic impairment","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["Do not stop this medicine abruptly, as it may worsen angina or cause heart attack.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Can mask symptoms of hypoglycemia in diabetics.","May worsen asthma or COPD; use with caution.","Can cause hyperkalemia; monitor potassium levels.","May cause fetal harm; avoid in pregnancy.","Use with caution in elderly patients; monitor renal function.","May cause skin reactions; report any rash.","Avoid alcohol while taking this medicine.","Inform your doctor if you have a history of heart failure, kidney disease, or liver disease."]

🤱 Lactation Safety

Telmisartan is not recommended during breastfeeding due to lack of data. Metoprolol is excreted in breast milk in small amounts and may cause bradycardia in the infant. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe hypotension, bradycardia, heart failure, and bronchospasm. Seek immediate medical attention. Treatment is supportive and symptomatic, including activated charcoal if recent ingestion, IV fluids, atropine for bradycardia, and vasopressors for hypotension. Hemodialysis is not effective for telmisartan; metoprolol is not dialyzable.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop suddenly. Monitor your blood pressure and heart rate regularly. Avoid alcohol as it can enhance the blood pressure-lowering effect and cause dizziness. Inform your doctor if you have asthma, diabetes, kidney or liver disease, or are pregnant or planning pregnancy. This medicine can mask symptoms of low blood sugar in diabetics. Use caution while driving or operating machinery until you know how it affects you. Keep all follow-up appointments and lab tests as advised.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering and heart rate-slowing effects. Start with a lower dose and monitor closely. Risk of falls due to dizziness is higher. Regular monitoring of kidney function and electrolytes is advised.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated in pregnancy. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect blood pressure and heart rate. Your doctor may advise temporary discontinuation before surgery.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution due to interaction with metoprolol.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce blood pressure.
🥗
Follow a low-sodium diet (less than 2 grams of sodium per day).
😴
Engage in regular aerobic exercise like walking, swimming, or cycling.
💧
Limit alcohol and avoid smoking.
🧘
Practice stress-reduction techniques like yoga or meditation.
🌞
Get adequate sleep (7-8 hours per night).

🏋️ Exercise Considerations

Avoid strenuous exercise initially as it may cause dizziness or low blood pressure. Start with light activities and gradually increase. Stay hydrated. If you experience chest pain, shortness of breath, or severe dizziness during exercise, stop and consult your doctor.

🥗 Diet Recommendations

Reduce salt intake.
Increase potassium-rich foods (if not contraindicated).
Include plenty of fruits and vegetables.
Choose whole grains over refined grains.
Limit saturated fats and cholesterol.
Avoid excessive caffeine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue, especially when you start treatment. Avoid driving or operating heavy machinery until you know how it affects you. Take breaks if you feel dizzy. Inform your employer if your job involves safety-sensitive tasks.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your blood pressure is well-controlled for a long time, your doctor may adjust or stop the medicine. Abrupt withdrawal can cause serious heart problems.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored. Regular check-ups for blood pressure, heart rate, kidney function, and electrolytes are necessary. It may reduce cardiovascular risk. Do not stop without medical advice.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and weight loss can help control blood pressure and may reduce medication needs.

Evidence: Well-established
Other antihypertensive combinations

Your doctor may switch to other combinations like ARB + CCB or ARB + diuretic if this medicine is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before any vaccination. Continue routine vaccinations as recommended.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage. If traveling across time zones, consult your doctor about adjusting the timing. Store at room temperature and avoid extreme heat. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with hypertension not controlled on telmisartan alone.
He was prescribed this medicine once daily. After 2 weeks, his blood pressure normalized. He experienced mild dizziness initially, which resolved. He was advised to monitor his pulse and avoid alcohol.
💡 Lesson: Combination therapy can effectively control blood pressure when monotherapy fails. Regular monitoring is key.
👤 A 62-year-old woman with a history of heart attack and angina.
She was started on this medicine for secondary prevention. Her angina episodes reduced significantly. She was cautioned not to stop the medicine suddenly. She maintained a healthy lifestyle and regular follow-ups.
💡 Lesson: This medicine provides dual benefits in post-MI patients. Adherence and lifestyle changes improve outcomes.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but full effect may take 1-2 weeks of regular use.

Q: Can I take it at night?

A: It is usually taken in the morning. However, your doctor may advise night dosing based on your blood pressure pattern. Follow your doctor's instructions.

Q: What if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose. Do not double dose.

Q: Is it safe during pregnancy?

A: No, this medicine is contraindicated in pregnancy as it can harm the fetus. Consult your doctor for alternative treatment.

Q: Can I stop taking it suddenly?

A: No, stopping suddenly can cause rebound hypertension or heart problems. Always consult your doctor before stopping.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for davaindia telmisartan+metoprolol succinate 40mg/50mg tablet er

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often requires lifelong treatment. Stopping suddenly can cause rebound hypertension or heart problems.
  • Myth: It causes kidney damage in everyone.
    Fact: Kidney problems are rare and usually occur in patients with pre-existing kidney disease or volume depletion. Regular monitoring is important.
  • Myth: It is safe to take during pregnancy.
    Fact: This medicine is contraindicated in pregnancy as it can harm the fetus.

🔄 Alternative Options

Generic Alternatives

  • Telmisartan 40 mg + Metoprolol Succinate 50 mg tablet

Brand Alternatives

  • Arbitel-MT 50 Tablet ER

📊 Comparison with Similar Medicines

[{"medicine":"Arbitel-MT 50 Tablet ER","composition":"Telmisartan 40 mg + Metoprolol Succinate 50 mg","release":"ER","frequency":"Once daily"},{"medicine":"Telmisartan + Metoprolol Tartrate","composition":"Telmisartan 40 mg + Metoprolol Tartrate 50 mg","release":"IR","frequency":"Twice daily"},{"medicine":"Telmisartan + Amlodipine","composition":"Telmisartan 40 mg + Amlodipine 5 mg","release":"IR","frequency":"Once daily"}]

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