veldix p 25 mg/500 mg tablet - Dexketoprofen (25mg) + Paracetamol (500mg) medicine

Neyta 25 Mg/500 Mg Tablet: Complete Medicine Guide

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🏭 Emcure Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 26, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. NSAIDs are generally avoided in the third trimester due to risk of premature closure of ductus arteriosus and other complications. Paracetamol is considered relatively safe in all trimesters when used at recommended doses. Consult your doctor before use. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for short-term acute pain management.
Reviewed by
SaathiMed Expert Panel | Oct 26, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising

If experiencing severe symptoms, call emergency services immediately.

What is veldix p 25 mg/500 mg tablet used for?

This medicine is a combination of dexketoprofen and paracetamol used for short-term relief of acute moderate to severe pain. It works by reducing inflammation and pain signals. Take it with food, avoid alcohol, and do not exceed 3 tablets in 24 hours.

  • Generic Name: Dexketoprofen (25mg) + Paracetamol (500mg)
  • Manufacturer: Emcure Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 veldix p 25 mg/500 mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा डेक्सकीटोप्रोफेन और पैरासिटामोल का संयोजन है, जिसका उपयोग तीव्र दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह मांसपेशियों के दर्द, दांत दर्द, सर्जरी के बाद के दर्द और मासिक धर्म के दर्द में राहत देती है। इसे भोजन के साथ लें और शराब से बचें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, पेट दर्द, सिरदर्द, चक्कर आना और दस्त शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट से खून बहना, एलर्जी, गुर्दे या यकृत की समस्या शामिल हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। इसे भोजन के साथ लें ताकि पेट की जलन कम हो। शराब का सेवन न करें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे, यकृत या हृदय की समस्या है, तो डॉक्टर से परामर्श करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 veldix p 25 mg/500 mg tablet Uses & Benefits

[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation in conditions such as sprains, strains, and low back pain.","evidence":"Well-established"},{"condition":"Dental pain","description":"Provides effective relief from toothache and pain following dental procedures.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Used for short-term management of moderate to severe pain after surgery.","evidence":"Well-established"},{"condition":"Dysmenorrhea","description":"Reduces menstrual cramps and associated pain.","evidence":"Well-established"},{"condition":"Fever","description":"Paracetamol component helps reduce fever, though the primary use is for pain.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine","description":"Sometimes used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"},{"condition":"Renal colic","description":"May be used off-label for pain relief in kidney stones, but other options are preferred.","evidence":"Limited"}]

Primary treatment for: Acute pain

Also treats: Musculoskeletal pain, Dental pain, Post-operative pain, Dysmenorrhea

📋 Drug Information

Generic Name(s)Dexketoprofen (25mg) + Paracetamol (500mg)
Brand Nameveldix p 25 mg/500 mg tablet
ManufacturerEmcure Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Do not exceed 3 tablets in 24 hours.
3
Avoid alcohol while taking this medicine.
4
Do not take other NSAIDs or paracetamol-containing products simultaneously.
5
Consult your doctor if pain persists beyond 5 days.
6
Report any signs of gastrointestinal bleeding immediately.
7
Stay well hydrated throughout the day.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Acute musculoskeletal pain
This medicine is commonly prescribed for this.
Likely Use
✅
Dental pain
This medicine is effective for dental pain.
Likely Use
❌
Fever
This medicine is not a primary fever reducer, though paracetamol may help.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDexketoprofen is rapidly absorbed after oral administration, with peak plasma concentrations reached within 30 minutes. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract, with peak levels occurring within 30 to 60 minutes.
DistributionDexketoprofen is highly bound to plasma proteins (99%) and has a small volume of distribution. Paracetamol distributes widely into most body tissues, with a volume of distribution of about 0.95 L/kg.
Protein BindingDexketoprofen: approximately 99% bound to plasma proteins, mainly albumin. Paracetamol: approximately 10-25% bound to plasma proteins.
MetabolismDexketoprofen is metabolized in the liver primarily by conjugation with glucuronic acid and sulfate, and to a lesser extent by CYP2C9-mediated hydroxylation. Paracetamol is metabolized in the liver via glucuronidation and sulfation; a small fraction is oxidized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeDexketoprofen: approximately 1-2 hours. Paracetamol: approximately 2-3 hours.
ExcretionDexketoprofen is excreted mainly in the urine as conjugates. Paracetamol is excreted in the urine as glucuronide and sulfate conjugates, with less than 5% excreted unchanged.
BioavailabilityDexketoprofen: approximately 70-80% after oral administration. Paracetamol: approximately 80-90% after oral administration.
Onset of ActionPain relief typically begins within 30 minutes after oral intake.
Peak Plasma TimeDexketoprofen: 0.5 hours. Paracetamol: 0.5-1 hour.
Duration of ActionPain relief lasts approximately 4-6 hours.

How It Works

This medicine combines two analgesics with complementary mechanisms. Dexketoprofen is the active dextrorotatory enantiomer of ketoprofen. It reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), leading to decreased synthesis of prostaglandins, prostacyclin, and thromboxane from arachidonic acid. This results in analgesic, anti-inflammatory, and antipyretic effects. Paracetamol acts primarily in the central nervous system by inhibiting prostaglandin synthesis and possibly activating descending serotonergic pathways, producing analgesia and antipyresis. The combination provides faster and stronger pain relief than either agent alone.

Mechanism Steps

1
Inhibition of cyclooxygenase: Dexketoprofen reversibly inhibits COX-1 and COX-2 enzymes, blocking the conversion of arachidonic acid to prostaglandin H2.
2
Reduced prostaglandin synthesis: This leads to decreased production of pain- and inflammation-mediating prostaglandins in peripheral tissues.
3
Central analgesic action of paracetamol: Paracetamol acts on the central nervous system to inhibit prostaglandin synthesis and modulate pain perception.
4
Combined analgesic effect: The two mechanisms work together to provide rapid and effective relief from acute pain.

💡 How to Take veldix p 25 mg/500 mg tablet

Strength: Each tablet contains dexketoprofen 25 mg and paracetamol 500 mg.

1Take the tablet orally with a full glass of water.
2Take it with food or immediately after a meal to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the prescribed dose and frequency exactly.
5Do not take more than 3 tablets in 24 hours.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 8 hours as needed for pain, not to exceed three tablets in 24 hours. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose or duration. Take with food to reduce stomach upset.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially gastrointestinal and renal effects. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician based on renal and hepatic function.
Renal ImpairmentUse with caution in patients with mild to moderate renal impairment. Dose reduction may be necessary. Contraindicated in severe renal impairment (creatinine clearance <30 mL/min). Consult a clinician for individualized dosing.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. Dose reduction may be necessary. Contraindicated in severe hepatic impairment. Consult a clinician for individualized dosing.
Maximum Daily DoseMaximum 3 tablets in 24 hours (75 mg dexketoprofen and 1500 mg paracetamol). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than 4 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 4 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of veldix p 25 mg/500 mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Stomach pain (Common (5-10%))
Take with food or milk. Avoid alcohol. If severe, contact your doctor.
Headache (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Diarrhea (Common (5-10%))
Stay hydrated. If it persists for more than 2 days, consult your doctor.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe abdominal pain.
Allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency help if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Acute kidney injury (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor immediately.
Hepatotoxicity (Rare (<0.1%))
Watch for yellowing of skin or eyes, dark urine, or right upper abdominal pain. Seek medical attention.
Cardiovascular events (myocardial infarction, stroke) (Rare (<0.1%))
Seek immediate care for chest pain, shortness of breath, or sudden weakness on one side.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek emergency care for severe blistering rash, peeling skin, or sores in mouth.
Agranulocytosis
Report sudden fever, sore throat, or mouth ulcers to your doctor immediately.
Aseptic meningitis
Seek medical attention for severe headache, stiff neck, fever, and sensitivity to light.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Other NSAIDs Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
Diuretics Moderate
SSRIs Moderate
Alcohol Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • SSRIs
  • Alcohol

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver toxicity, especially with paracetamol. It can also enhance the central nervous system effects such as dizziness and drowsiness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to dexketoprofen, paracetamol, or any component","Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure, ischemic heart disease, peripheral arterial disease, or cerebrovascular disease","Severe hepatic impairment","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["Take with food to minimize gastrointestinal irritation.","Avoid alcohol consumption.","Do not exceed the recommended dose or duration.","Use with caution in elderly patients due to increased risk of adverse effects.","Monitor renal and hepatic function during prolonged use.","Discontinue if signs of gastrointestinal bleeding occur.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you have a history of cardiovascular disease, hypertension, or diabetes.","Do not use for more than 5 days without medical advice.","Keep out of reach of children."]

🤱 Lactation Safety

Dexketoprofen is not recommended during breastfeeding as it may pass into breast milk and cause adverse effects in the infant. Paracetamol is considered safe during breastfeeding. Consult your doctor for alternative pain relief.

💊 Overdose Management

Overdose can cause severe liver damage from paracetamol and gastrointestinal bleeding, renal failure, and central nervous system effects from dexketoprofen. Seek immediate medical attention. Treatment includes activated charcoal if within 1-2 hours, N-acetylcysteine for paracetamol toxicity, and supportive care. Monitor liver and renal function, and vital signs.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Take it with food or a glass of water to reduce the risk of stomach upset. Avoid alcohol while taking this medicine, as it can increase the risk of gastrointestinal bleeding and liver damage. Do not take other NSAIDs or paracetamol-containing products simultaneously to prevent overdose. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function closely. Avoid in patients with severe renal or hepatic impairment.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. NSAIDs may affect ovulation and are not recommended during the third trimester. Paracetamol is generally considered safe, but always consult your doctor.

🏥 Post-Surgery Considerations

This medicine may be used for post-operative pain, but it should be used with caution due to increased risk of bleeding and renal effects. Follow your surgeon's instructions. Do not use for prolonged periods without medical supervision.

🦷 Dental Procedures

This medicine can be used for dental pain, but inform your dentist if you are taking it before any dental procedure. It may increase bleeding risk during dental surgery. Your dentist may advise stopping it temporarily.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce stress on joints.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture and ergonomics.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep to aid recovery.
🌞
Stay hydrated throughout the day.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while experiencing acute pain. Gentle stretching and low-impact activities may be beneficial once pain subsides. Consult your doctor before resuming intense physical activity.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed and fried food intake.
Stay well hydrated.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may affect your ability to concentrate. Take it with food to minimize stomach upset and maintain productivity.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience any serious side effects such as gastrointestinal bleeding, allergic reactions, or severe abdominal pain. Do not stop abruptly if you have been taking it for a prolonged period without consulting your doctor. Usually, it is stopped when pain resolves.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended due to increased risk of gastrointestinal bleeding, kidney damage, liver toxicity, and cardiovascular events. If prolonged use is necessary, regular monitoring of renal and hepatic function, blood counts, and blood pressure is required. Review with your doctor periodically.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain management.

Evidence: Well-established
Hot/cold therapy

May help relieve localized pain and inflammation.

Evidence: Limited
Acupuncture

Some evidence for pain relief in certain conditions.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine. There is no need to postpone vaccination unless advised by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing intervals as advised by your doctor. Declare it at customs if required. Do not expose to extreme temperatures.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with acute low back pain
Started this medicine as prescribed for acute low back pain. Within 30 minutes, pain relief was noticeable. Took it with food to prevent stomach upset. After 3 days, pain significantly reduced and stopped the medicine as advised.
💡 Lesson: Taking this medicine with food improves tolerability, and short-term use as prescribed is effective for acute pain.
👤 A 30-year-old woman with dysmenorrhea
Used this medicine for menstrual cramps. It provided rapid relief, allowing her to continue daily activities. She was advised not to exceed 3 tablets per day and to avoid alcohol.
💡 Lesson: This medicine can effectively manage acute pain, but adherence to dosage limits is crucial for safety.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts relieving pain within 30 minutes after oral intake.

Q: How long can I take this medicine?

A: It is intended for short-term use only, usually for a few days. Do not use for more than 5 days without medical advice.

Q: Can I take this medicine with alcohol?

A: No, alcohol should be avoided as it increases the risk of gastrointestinal bleeding and liver damage.

Q: Is this medicine safe for kidney patients?

A: It should be used with caution in patients with kidney disease. It is contraindicated in severe renal impairment. Consult your doctor.

Q: Can I take this medicine during pregnancy?

A: It is not recommended during the third trimester. Consult your doctor before use if you are pregnant or planning to become pregnant.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for veldix p 25 mg/500 mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be taken long-term for chronic pain.
    Fact: This medicine is intended for short-term use only, usually for a few days. Long-term use increases the risk of serious side effects.
  • Myth: It is safe to take extra doses if pain is severe.
    Fact: Taking more than the recommended dose can cause severe liver damage and gastrointestinal bleeding. Never exceed the prescribed dose.
  • Myth: This medicine is safe to take with other painkillers.
    Fact: Combining with other NSAIDs or paracetamol-containing products can lead to overdose and serious side effects. Always consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Dexketoprofen 25 mg + Paracetamol 500 mg tablet

Brand Alternatives

  • Neyta 25 mg/500 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Dexketoprofen 25 mg + Paracetamol 500 mg","onset":"30 minutes","duration":"4-6 hours","notes":"Rapid onset, short-term use"},{"medicine":"Ibuprofen + Paracetamol","composition":"Ibuprofen 400 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Similar efficacy, different NSAID"},{"medicine":"Diclofenac + Paracetamol","composition":"Diclofenac 50 mg + Paracetamol 500 mg","onset":"30-60 minutes","duration":"4-6 hours","notes":"Similar efficacy, different NSAID"}]

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