asomex-at tablet - Amlodipine (2.5mg) + Atenolol (50mg) medicine

Asomex-AT Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Emcure Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension and angina.
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

When to Call Your Doctor IMMEDIATELY

  • Very slow heart rate (below 50 beats per minute) or fainting
  • Severe dizziness or lightheadedness
  • Chest pain that worsens or does not go away
  • Sudden weight gain or swelling in legs and feet
  • Difficulty breathing or wheezing
  • Swelling of face, lips, or throat
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is asomex-at tablet used for?

This medicine is a combination of Amlodipine and Atenolol used to treat high blood pressure and angina. It works by relaxing blood vessels and slowing the heart rate. Take it exactly as prescribed, and do not stop suddenly.

  • Generic Name: Amlodipine + Atenolol
  • Manufacturer: Emcure Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 asomex-at tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एम्लोडिपिन और एटेनोलोल का संयोजन है, जिसका उपयोग उच्च रक्तचाप (हाइपरटेंशन) और एंजाइना (सीने में दर्द) के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। इसे डॉक्टर के निर्देशानुसार नियमित रूप से लें और अचानक बंद न करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, पैरों या टखनों में सूजन, और हृदय की गति धीमी होना शामिल है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें बहुत धीमी हृदय गति, बेहोशी, या एलर्जी की प्रतिक्रिया शामिल हो सकती है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें क्योंकि इससे रक्तचाप बढ़ सकता है या सीने में दर्द हो सकता है। इस दवा के साथ शराब न पिएं। बैठने या लेटने से उठते समय धीरे-धीरे उठें। यदि आपको मधुमेह है तो अपने रक्त शर्करा की निगरानी करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 asomex-at tablet Uses & Benefits

[{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure when a single medicine is not enough or when combination therapy is considered appropriate.","evidence":"Well-established"},{"condition":"Angina pectoris","description":"It may be prescribed to reduce the frequency and severity of angina attacks by lowering heart rate and blood pressure, thereby decreasing the heart's oxygen demand.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Migraine prophylaxis","description":"Sometimes prescribed off-label to prevent migraines, though evidence is limited and it is not a first-line option.","evidence":"Limited"},{"condition":"Performance anxiety","description":"Beta-blockers like atenolol are occasionally used off-label to reduce symptoms of performance anxiety, but this combination is not standard for that purpose.","evidence":"Limited"}]

Primary treatment for: Hypertension

Also treats: Angina pectoris

📋 Drug Information

Generic Name(s)Amlodipine + Atenolol
Brand NameAmlokind-AT Tablet
ManufacturerEmcure Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassCARDIAC
Action ClassCalcium channel blocker + Beta blocker
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Monitor your blood pressure and heart rate regularly at home.
3
Do not stop this medicine abruptly; always consult your doctor before making changes.
4
Avoid alcohol as it can increase dizziness and low blood pressure.
5
If you have diabetes, check your blood sugar regularly as this medicine can mask low blood sugar symptoms.
6
Report any swelling of ankles, unusual tiredness, or slow pulse to your doctor.
7
Inform your doctor if you are planning pregnancy or are breastfeeding.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

High blood pressure
This medicine is commonly prescribed for this.
Likely Use
Chest pain (angina)
This medicine can help reduce angina attacks.
Likely Use
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmlodipine is well absorbed after oral administration, with peak levels reached in 6 to 12 hours. Atenolol is incompletely absorbed, with about 50% bioavailability.
DistributionAmlodipine is highly protein-bound and distributes widely. Atenolol has low protein binding and distributes mainly in extracellular fluid.
Protein BindingAmlodipine is approximately 93% bound to plasma proteins. Atenolol is about 3% bound.
MetabolismAmlodipine is extensively metabolized in the liver, primarily by CYP3A4. Atenolol is minimally metabolized and is excreted largely unchanged by the kidneys.
Half-LifeAmlodipine has a half-life of 30 to 50 hours. Atenolol has a half-life of 6 to 7 hours.
ExcretionAmlodipine metabolites are excreted mainly in urine. Atenolol is excreted primarily unchanged in urine.
BioavailabilityAmlodipine bioavailability is about 64% to 90%. Atenolol bioavailability is about 50%.
Onset of ActionAmlodipine onset is gradual, with antihypertensive effect within 24 hours. Atenolol onset is within 1 hour.
Peak Plasma TimeAmlodipine peak plasma time is 6 to 12 hours. Atenolol peak plasma time is 2 to 4 hours.
Duration of ActionAmlodipine effect lasts 24 hours. Atenolol effect lasts about 24 hours with once-daily dosing.

How It Works

This medicine combines two active ingredients with complementary actions. Amlodipine blocks calcium channels in the smooth muscle of blood vessels, causing them to relax and widen, which lowers blood pressure and improves blood flow. Atenolol selectively blocks beta-1 receptors in the heart, reducing heart rate, contractility, and cardiac output, which also lowers blood pressure and decreases the heart's oxygen demand. Together, they reduce blood pressure through different but synergistic mechanisms.

Mechanism Steps

1
Calcium channel blockade by amlodipine: Amlodipine binds to L-type calcium channels in vascular smooth muscle, preventing calcium entry and causing relaxation and vasodilation.
2
Beta-1 receptor blockade by atenolol: Atenolol blocks beta-1 adrenergic receptors in the heart, reducing heart rate, contractility, and cardiac output.
3
Combined blood pressure reduction: The vasodilation from amlodipine and the reduced cardiac output from atenolol work together to lower blood pressure effectively.
4
Reduced cardiac oxygen demand: By slowing the heart and lowering blood pressure, the heart requires less oxygen, which helps in angina.

💡 How to Take asomex-at tablet

Strength: Tablet containing Amlodipine 2.5 mg and Atenolol 50 mg.

1Take this medicine at the same time each day, preferably in the morning.
2Swallow the tablet whole with a glass of water.
3You can take it with or without food, but taking it with food may reduce stomach upset.
4Do not crush, chew, or break the tablet unless your doctor advises.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet of Amlodipine 2.5 mg and Atenolol 50 mg taken orally once daily, with or without food. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. Do not adjust the dose without medical advice.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially dizziness and slow heart rate. Start with a lower dose and monitor closely.
Renal ImpairmentAtenolol is excreted by the kidneys. In renal impairment, dose reduction may be necessary. Consult your doctor for dose adjustment.
Hepatic ImpairmentAmlodipine is metabolized by the liver. In hepatic impairment, start with a lower dose and monitor carefully.
Maximum Daily DoseThe maximum recommended daily dose is Amlodipine 10 mg and Atenolol 100 mg, but this must be determined by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Can be taken with or without food
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase amlodipine levels.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours late
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours late
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of asomex-at tablet

✅ Common Side Effects

Dizziness (Common (5-10%))
Rise slowly from sitting or lying positions. Avoid driving if dizzy.
Tiredness (Common (5-10%))
Rest if needed. If persistent, consult your doctor.
Swelling of ankles or feet (Common (5-10%))
Elevate your legs when sitting. Report to doctor if severe.
Headache (Common (5-10%))
Usually resolves. Consult doctor if severe or persistent.
Slow heartbeat (Common (5-10%))
Report to doctor if pulse is below 50 beats per minute or you feel faint.

🚨 Serious Side Effects

Severe bradycardia (very slow heart rate) (Rare (<0.1%))
Seek immediate medical attention if you feel faint, extremely tired, or have a pulse below 50.
Heart block (Rare (<0.1%))
Go to the emergency room if you experience chest pain, fainting, or severe dizziness.
Worsening heart failure (Rare (<0.1%))
Contact your doctor immediately if you have sudden weight gain, swelling, or difficulty breathing.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you have swelling of face, lips, throat, or difficulty breathing.

⚠️ Rare Side Effects

Bronchospasm
Seek medical help if you develop wheezing or difficulty breathing.
Raynaud's phenomenon
Report to doctor if fingers or toes turn white or blue in cold.
Depression
Consult your doctor if you feel persistently sad or hopeless.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Verapamil Major
Clonidine Major
Digoxin Major
NSAIDs Moderate
CYP3A4 inhibitors Moderate
Oral hypoglycemics Moderate
Antacids Minor
Grapefruit juice Minor

🚨 Major Interactions

  • Verapamil or diltiazem
  • Clonidine
  • Digoxin

⚡ Moderate Interactions

  • NSAIDs (e.g., ibuprofen)
  • CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
  • Oral hypoglycemics

🍷 Alcohol Interaction

Alcohol can increase the blood pressure-lowering effect of this medicine, leading to dizziness, fainting, or a dangerous drop in blood pressure. It is best to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Severe bradycardia","Second or third-degree heart block","Cardiogenic shock","Severe heart failure","History of asthma or severe COPD","Hypersensitivity to amlodipine or atenolol"]

⚠️ Warnings & Precautions

["Do not stop this medicine suddenly; taper gradually under medical supervision.","May mask symptoms of hypoglycemia in diabetics.","May worsen heart failure; monitor for weight gain and swelling.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Use with caution in elderly and in patients with kidney or liver disease."]

🤱 Lactation Safety

Amlodipine and atenolol are excreted in breast milk. Atenolol may accumulate in breastfed infants. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose can cause severe low blood pressure, slow heart rate, heart failure, and shock. Seek emergency medical help immediately. Treatment is supportive and may include intravenous fluids, atropine, glucagon, or pacemaker insertion.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as this can cause a dangerous rise in blood pressure or chest pain. Avoid drinking alcohol while taking this medicine because it can increase dizziness and lower your blood pressure too much. Stand up slowly from a sitting or lying position to prevent dizziness. If you have diabetes, be aware that this medicine may hide signs of low blood sugar such as a fast heartbeat. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep all your doctor appointments and get your blood pressure, heart rate, and kidney function checked regularly. Do not take any new medicine, including over-the-counter products, without asking your doctor or pharmacist first.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine, especially dizziness and slow heart rate. Start with a lower dose and monitor closely. Regular monitoring of kidney function is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It may not be suitable during pregnancy. Your doctor may switch you to a safer alternative.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthesia and affect heart rate and blood pressure during surgery. Do not stop unless advised.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine. It may cause dry mouth or affect blood pressure during dental procedures. Local anesthesia with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Reduce salt intake to less than 5 grams per day.
😴
Engage in regular moderate exercise like brisk walking for 30 minutes most days.
💧
Avoid smoking and limit alcohol consumption.
🧘
Practice stress-reducing techniques such as deep breathing or meditation.
🌞
Get adequate sleep (7-8 hours per night).

🏋️ Exercise Considerations

This medicine may cause dizziness or slow heart rate, especially when starting treatment or increasing dose. Avoid strenuous exercise until you know how the medicine affects you. Stay hydrated during exercise.

🥗 Diet Recommendations

Follow a DASH diet rich in fruits, vegetables, and low-fat dairy.
Limit sodium intake.
Avoid grapefruit and grapefruit juice.
Include potassium-rich foods like bananas and oranges if your kidneys are healthy.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or tiredness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities with dose adjustment.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.

📅 Long-Term Use Effects

Long-term use of this medicine is generally safe when monitored by a doctor. Regular check-ups of blood pressure, heart rate, kidney function, and electrolytes are recommended. Do not stop suddenly. Long-term uncontrolled hypertension can lead to heart attack, stroke, and kidney damage, so consistent treatment is important.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, weight loss, and stress reduction can help lower blood pressure and may reduce the need for medication.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, ARBs, diuretics, or other calcium channel blockers may be alternatives if this medicine is not suitable.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Continue routine vaccinations as recommended by your doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the timing. Carry enough supply for the entire trip.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with high blood pressure not controlled on a single medicine.
He was prescribed this medicine once daily. After 4 weeks, his blood pressure was well controlled. He experienced mild dizziness initially, which improved after a few days. He was advised not to stop the medicine suddenly.
💡 Lesson: Combination therapy can effectively control blood pressure when a single medicine is not enough. Regular monitoring and adherence are key.
👤 A 62-year-old woman with angina and hypertension.
She started this medicine and noticed fewer angina attacks. She was cautioned about slow heart rate and advised to report if her pulse dropped below 50. She also learned to avoid alcohol and to rise slowly from sitting.
💡 Lesson: This medicine can reduce angina frequency, but patients must be aware of potential side effects and take precautions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 24 hours, but full effect may take 1 to 2 weeks.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms and requires long-term treatment.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my other blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for asomex-at tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can be dangerous.
  • Myth: This medicine damages the kidneys.
    Fact: Uncontrolled high blood pressure damages kidneys. This medicine helps protect them by controlling blood pressure.
  • Myth: You can take this medicine only when you feel unwell.
    Fact: This medicine must be taken regularly, even if you feel fine, to control blood pressure and prevent complications.

🔄 Alternative Options

Generic Alternatives

  • Amlodipine 2.5 mg + Atenolol 50 mg tablet (generic)

Brand Alternatives

  • Asomex-AT Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Amlodipine 2.5 mg + Atenolol 50 mg","frequency":"Once daily","notes":"Combination for hypertension."},{"medicine":"Amlodipine 5 mg + Atenolol 50 mg","composition":"Amlodipine 5 mg + Atenolol 50 mg","frequency":"Once daily","notes":"Higher amlodipine strength."},{"medicine":"Amlodipine 2.5 mg + Metoprolol 50 mg","composition":"Amlodipine 2.5 mg + Metoprolol 50 mg","frequency":"Once daily","notes":"Metoprolol instead of atenolol."}]

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