vasmed injection - Vasopressin (20IU) medicine

Petresin 20IU Injection: Comprehensive Medicine Guide

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🏭 United Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for primary uses.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Severe chest pain or shortness of breath
  • Sudden severe headache or confusion
  • Seizures or loss of consciousness
  • Cold, pale, or painful extremities
  • Decreased urine output or swelling
  • Severe allergic reaction (swelling of face, lips, throat)

If experiencing severe symptoms, call emergency services immediately.

What is vasmed injection used for?

This medicine contains vasopressin 20 IU, a synthetic hormone used to treat vasodilatory shock and central diabetes insipidus. It works by constricting blood vessels and reducing urine output. It is given only by healthcare professionals in a hospital setting.

  • Generic Name: Vasopressin (20IU)
  • Manufacturer: United Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 vasmed injection के बारे में (Hindi Summary)

उपयोग: यह दवा वैसोप्रेसिन 20 IU इंजेक्शन है, जिसका उपयोग गंभीर रूप से निम्न रक्तचाप (वैसोडिलेटरी शॉक) और केंद्रीय मधुमेह इन्सिपिडस के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को संकुचित करके रक्तचाप बढ़ाती है और गुर्दे में पानी के पुनर्अवशोषण को बढ़ाकर पेशाब की मात्रा कम करती है। यह दवा केवल अस्पताल में डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जाती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, मतली, पेट में ऐंठन और त्वचा का पीला पड़ना शामिल हैं। गंभीर दुष्प्रभावों में उच्च रक्तचाप, धीमी हृदय गति, दिल का दौरा और पानी का असंतुलन हो सकता है। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर को सूचित करें।

सुरक्षा सलाह: यह दवा केवल अस्पताल में प्रशिक्षित स्वास्थ्यकर्मी द्वारा दी जानी चाहिए। उपचार के दौरान रक्तचाप, हृदय गति और इलेक्ट्रोलाइट्स की निगरानी आवश्यक है। इसे घर पर स्वयं न लगाएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 vasmed injection Uses & Benefits

[{"condition":"Vasodilatory shock (e.g., septic shock)","description":"Used to increase blood pressure in patients with vasodilatory shock who are not responding to fluid resuscitation and other vasopressors.","evidence":"Well-established"},{"condition":"Central diabetes insipidus","description":"Used to treat central diabetes insipidus by replacing the deficient antidiuretic hormone, reducing excessive urination and thirst.","evidence":"Well-established"},{"condition":"Cardiac arrest (adjunct)","description":"Sometimes used as an adjunct in cardiac arrest resuscitation, though evidence is mixed.","evidence":"Limited"},{"condition":"Gastrointestinal bleeding (variceal)","description":"Used to constrict splanchnic vessels and reduce portal pressure in variceal bleeding.","evidence":"Established"}]

Off-label uses: [{"condition":"Nocturnal enuresis","description":"Rarely used off-label for bedwetting in children, but not standard.","evidence":"Limited"},{"condition":"Postoperative abdominal distension","description":"Occasionally used to stimulate bowel motility, but evidence is weak.","evidence":"Limited"}]

Primary treatment for: Vasodilatory shock

Also treats: Central diabetes insipidus, Variceal bleeding

📋 Drug Information

Generic Name(s)Vasopressin (20IU)
Brand Namevasmed injection
ManufacturerUnited Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassVasopressin analogues
Route of AdministrationParenteral (intravenous or intramuscular)
StorageStore refrigerated at 2-8°C. Do not freeze. Protect from light.
Shelf LifeRefer to the manufacturer's label. Typically 24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer only in a monitored setting with continuous blood pressure and heart rate monitoring.
2
Ensure adequate fluid resuscitation before starting vasopressin for shock.
3
Monitor serum sodium levels regularly to avoid hyponatremia.
4
Use a central line for infusion to reduce risk of extravasation.
5
Titrate the dose carefully to the desired clinical response.
6
Be cautious when using with other vasopressors to avoid excessive hypertension.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Low blood pressure
This medicine is used to treat vasodilatory shock.
Likely Use
✅
Excessive urination
This medicine is used for central diabetes insipidus.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionVasopressin is administered parenterally and is rapidly absorbed into the bloodstream. Bioavailability is not applicable for intravenous route as it is directly introduced into circulation.
DistributionVasopressin distributes throughout the extracellular fluid. It does not cross the blood-brain barrier significantly.
Protein BindingLow, approximately 1-10% bound to plasma proteins.
MetabolismVasopressin is metabolized primarily in the liver and kidneys by proteolytic enzymes.
Half-LifeThe plasma half-life is short, approximately 10-20 minutes.
ExcretionMetabolites are excreted primarily in the urine.
BioavailabilityNot applicable for intravenous administration; for intramuscular, bioavailability is high but not well characterized.
Onset of ActionIntravenous: within 1-2 minutes. Intramuscular: within 15-30 minutes.
Peak Plasma TimeIntravenous: immediate. Intramuscular: within 30-60 minutes.
Duration of ActionAntidiuretic effect lasts 2-8 hours depending on dose and route. Vasopressor effect is short-lived, requiring continuous infusion.

How It Works

Vasopressin acts on V1 receptors on vascular smooth muscle to cause vasoconstriction, and on V2 receptors in the renal collecting ducts to increase water permeability and reabsorption. This leads to increased blood pressure and reduced urine output.

Mechanism Steps

1
V1 receptor activation: Vasopressin binds to V1 receptors on vascular smooth muscle, triggering intracellular calcium release and smooth muscle contraction.
2
Vasoconstriction: Contraction of vascular smooth muscle leads to narrowing of blood vessels and increased systemic vascular resistance.
3
V2 receptor activation: Vasopressin binds to V2 receptors in the renal collecting ducts, activating aquaporin-2 channels.
4
Water reabsorption: Insertion of aquaporin-2 channels into the apical membrane increases water permeability, allowing water reabsorption and concentrating urine.

💡 How to Take vasmed injection

Strength: Injection: 20 IU per vial

1This medicine is administered by a healthcare professional.
2It is given as an intravenous or intramuscular injection.
3The dose and rate are determined by the doctor based on your condition.
4Do not self-administer.

Dosage Information

Adult DosageDosage is individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. For vasodilatory shock, a common initial dose is 0.01-0.03 units/min intravenously, titrated to effect. For central diabetes insipidus, 5-10 units intramuscularly or subcutaneously two to three times daily. Dose must be individualized by a qualified clinician.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageUse with caution in elderly patients due to increased risk of cardiovascular events and electrolyte imbalances. Dose should be individualized by a qualified clinician.
Renal ImpairmentUse with caution in renal impairment. Monitor renal function and electrolytes. Dose adjustment may be necessary.
Hepatic ImpairmentUse with caution in hepatic impairment. Monitor liver function. Dose adjustment may be necessary.
Maximum Daily DoseNot established from the available information. Dose is titrated to clinical response under medical supervision.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Missed dose in hospital setting
→ Inform the nursing staff immediately.
💡 Do not attempt to self-administer.

⚠️ Side Effects of vasmed injection

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves; report if severe or persistent.
Nausea (Common (5-10%))
May be managed with antiemetics; inform your doctor if it interferes with eating.
Abdominal cramps (Common (5-10%))
Report to your doctor if severe or persistent.
Pale skin (Common (5-10%))
Usually transient; monitor for other symptoms.

🚨 Serious Side Effects

Severe hypertension (Uncommon (1-5%))
Requires immediate medical attention; blood pressure should be monitored closely.
Bradycardia (Uncommon (1-5%))
Monitor heart rate; report if slow or irregular heartbeat occurs.
Myocardial ischemia (Rare (<1%))
Seek immediate medical attention if chest pain or shortness of breath occurs.
Water intoxication with hyponatremia (Rare (<1%))
Monitor fluid balance and electrolytes; report confusion, seizures, or severe headache.

⚠️ Rare Side Effects

Anaphylaxis
Seek emergency medical help immediately if swelling of face, lips, throat, or difficulty breathing occurs.
Peripheral ischemia
Report cold, pale, or painful extremities to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Norepinephrine Major
Furosemide Major
Carbamazepine Moderate
NSAIDs Moderate
Alcohol Minor

🚨 Major Interactions

  • Other vasopressors (e.g., norepinephrine, epinephrine)
  • Diuretics (e.g., furosemide)

⚡ Moderate Interactions

  • Carbamazepine
  • NSAIDs

🍷 Alcohol Interaction

Alcohol may enhance vasodilation and counteract the vasopressor effect of this medicine. Avoid alcohol during treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to vasopressin","Chronic nephritis","Severe cardiovascular disease","Epilepsy"]

⚠️ Warnings & Precautions

["Use with caution in patients with asthma, heart failure, or migraine.","May cause water intoxication; monitor fluid intake and electrolytes.","Avoid extravasation; can cause tissue necrosis.","Use with caution in elderly and pediatric patients."]

🤱 Lactation Safety

Not established from the available information. Consult a healthcare provider before use during breastfeeding.

💊 Overdose Management

Overdose may cause severe hypertension, bradycardia, and water intoxication. Treatment is supportive and symptomatic. Monitor vital signs and electrolytes. In case of severe hypertension, consider vasodilators. For water intoxication, restrict fluids and monitor sodium levels.

⏰ Missed Dose

This medicine is administered by healthcare professionals in a controlled setting. Missed doses are unlikely to occur outside hospital. If a dose is missed in a hospital setting, follow institutional protocols.

Additional Safety Advice

General Safety

This medicine must be given only by a qualified healthcare professional in a monitored setting. Blood pressure, heart rate, and fluid balance should be closely monitored during administration. Do not use if the solution is discolored or contains particles. Inform your doctor about all medications you are taking, especially other vasopressors or diuretics.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of cardiovascular events and electrolyte imbalances. Use with caution and monitor closely.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy. Use only if clearly needed and under medical supervision.

🏥 Post-Surgery Considerations

May be used post-surgery for shock or diabetes insipidus. Monitor closely for fluid and electrolyte balance.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine. It may affect blood pressure and bleeding risk.

💚 Lifestyle Tips for Better Results

🏃
Follow a low-sodium diet if advised by your doctor.
🥗
Monitor your fluid intake as directed.
😴
Keep all follow-up appointments for monitoring.
💧
Report any new symptoms promptly.
🧘
Avoid alcohol during treatment.

🏋️ Exercise Considerations

Avoid strenuous exercise during treatment as it may exacerbate cardiovascular effects. Consult your doctor before resuming any exercise routine.

🥗 Diet Recommendations

Follow fluid restrictions if advised.
Maintain a balanced diet.
Limit sodium intake if you have high blood pressure.

💼 Impact on Daily Work & Life

This medicine is given in a hospital setting; it may require hospitalization. Driving and operating machinery should be avoided until cleared by your doctor.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. It is usually stopped when the underlying condition is controlled or as directed by the healthcare team.

📅 Long-Term Use Effects

Long-term use may lead to water retention, hyponatremia, and cardiovascular effects. Regular monitoring of electrolytes, blood pressure, and renal function is required. Use should be reviewed periodically by a clinician.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other vasopressors (e.g., norepinephrine)

May be used as alternatives or in combination for shock.

Evidence: Well-established
Desmopressin

Alternative for central diabetes insipidus.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions reported. Follow routine vaccination schedules as advised by your doctor.

📦 Storage Guide

✅ DO

Store refrigerated at 2-8°C

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not use if discolored or contains particles

✈️ Traveling with This Medicine

This medicine is administered in a hospital setting and is not for self-administration during travel. If you are prescribed vasopressin for home use (rare), carry it in its original packaging with a prescription copy. Store refrigerated (2-8°C) and use a cooler bag during travel. Check customs regulations for injectable medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 65-year-old man with septic shock in the ICU
He was not responding to fluids and norepinephrine. Vasopressin was added, and his blood pressure improved within minutes. He was monitored closely for electrolyte imbalances and recovered after several days.
💡 Lesson: Vasopressin can be life-saving in vasodilatory shock when used under close supervision.
👤 A 30-year-old woman with central diabetes insipidus
She had excessive urination and thirst after pituitary surgery. Vasopressin injection was given, and her urine output normalized. She was later switched to a nasal spray for long-term management.
💡 Lesson: Vasopressin effectively controls central diabetes insipidus and can be transitioned to other formulations.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Intravenous vasopressin works within 1-2 minutes; intramuscular within 15-30 minutes.

Q: Can I take this medicine at home?

A: No, this medicine must be given by a healthcare professional in a hospital setting.

Q: What are the serious side effects?

A: Serious side effects include severe hypertension, bradycardia, myocardial ischemia, and water intoxication.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How long will I need this medicine?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?

🔄 Substitutes for vasmed injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Vasopressin is a common painkiller.
    Fact: Vasopressin is not a painkiller; it is a vasopressor and antidiuretic hormone used in critical care.
  • Myth: Vasopressin can be self-administered.
    Fact: Vasopressin must be administered only by healthcare professionals in a monitored setting.

🔄 Alternative Options

Generic Alternatives

  • Vasopressin injection

Brand Alternatives

  • Petresin 20IU Injection

📊 Comparison with Similar Medicines

[{"medicine":"Vasopressin","class":"Vasopressor/antidiuretic","primary_use":"Vasodilatory shock, diabetes insipidus","route":"Parenteral"},{"medicine":"Terlipressin","class":"Vasopressin analogue","primary_use":"Variceal bleeding, hepatorenal syndrome","route":"Parenteral"},{"medicine":"Desmopressin","class":"Vasopressin analogue","primary_use":"Central diabetes insipidus, nocturnal enuresis","route":"Oral, intranasal, parenteral"}]

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