alkem nandrolone 50mg injection - Nandrolone Decanoate (50mg) medicine

Nandrolone Decanoate 50mg Injection: Complete Medical Guide

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🏭 Alkem Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Contraindicated in pregnancy. This medicine can cause harm to the fetus and is not recommended for use during pregnancy. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for approved indications; limited for off-label uses.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain or vomiting blood
  • Chest pain, shortness of breath, or swelling in one leg
  • Sudden weight gain or swelling of face, hands, or feet
  • Painful, prolonged erection (priapism)
  • Severe allergic reaction with rash, itching, or difficulty breathing
  • Decreased urine output or blood in urine

If experiencing severe symptoms, call emergency services immediately.

What is alkem nandrolone 50mg injection used for?

Nandrolone decanoate 50 mg injection is an anabolic steroid used to treat anaemia in chronic kidney disease and severe osteoporosis. It is given intramuscularly by a healthcare professional and must not be self-administered.

  • Generic Name: Nandrolone Decanoate
  • Manufacturer: Alkem Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 alkem nandrolone 50mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा नैंड्रोलोन डेकानोएट 50 मिलीग्राम इंजेक्शन है, जिसका उपयोग कुछ विशेष चिकित्सीय स्थितियों में किया जाता है। इसका मुख्य उपयोग किडनी की बीमारी से जुड़े एनीमिया, गंभीर ऑस्टियोपोरोसिस, और कुछ मांसपेशियों की कमजोरी की स्थितियों में होता है। यह दवा मांसपेशियों में इंजेक्शन द्वारा दी जाती है और इसे केवल डॉक्टर की देखरेख में ही लिया जाना चाहिए। यह दवा शरीर में प्रोटीन का निर्माण बढ़ाती है और लाल रक्त कोशिकाओं का उत्पादन बढ़ाती है। इसे बॉडीबिल्डिंग या खेल प्रदर्शन बढ़ाने के लिए नहीं लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, सूजन, मुँहासे, त्वचा का तैलीय होना, और शरीर में पानी का जमाव शामिल हैं। पुरुषों में स्तन में कोमलता, शुक्राणुओं की संख्या में कमी, और अंडकोष का छोटा होना हो सकता है। महिलाओं में आवाज भारी होना, चेहरे पर बाल आना, और मासिक धर्म में अनियमितता हो सकती है। गंभीर दुष्प्रभावों में लीवर की क्षति, रक्त के थक्के, और हृदय की समस्याएँ शामिल हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्यकर्मी द्वारा इंट्रामस्क्युलर इंजेक्शन के रूप में दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं और न ही सुई साझा करें। यदि आपको हृदय, लीवर, गुर्दे, प्रोस्टेट की समस्या, उच्च रक्तचाप, मधुमेह, या रक्त के थक्के की समस्या है तो डॉक्टर को बताएं। उपचार के दौरान लीवर फंक्शन, कोलेस्ट्रॉल, और रक्त की जांच नियमित रूप से करानी चाहिए। शराब और अन्य लीवर को नुकसान पहुंचाने वाली दवाओं से बचें। गर्भवती या गर्भधारण की योजना बनाने वाली महिलाओं को यह दवा नहीं लेनी चाहिए।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 alkem nandrolone 50mg injection Uses & Benefits

[{"condition":"Anaemia of chronic kidney disease","description":"Used to stimulate red blood cell production in selected patients with kidney failure who do not respond adequately to other treatments.","evidence":"Established in specialist practice"},{"condition":"Severe osteoporosis in postmenopausal women","description":"May be used as an adjunct to increase bone mineral density in carefully selected patients when other therapies are unsuitable.","evidence":"Limited to specialist use"},{"condition":"Muscle wasting in chronic illness","description":"Sometimes prescribed to promote weight gain and muscle mass in patients with HIV wasting or severe chronic disease.","evidence":"Limited evidence"},{"condition":"Hereditary angioedema","description":"Rarely used to prevent attacks by increasing levels of certain complement proteins.","evidence":"Case reports and small studies"}]

Off-label uses: [{"condition":"Male hypogonadism","description":"Occasionally used off-label for low testosterone, but not a first-line treatment.","evidence":"Limited"},{"condition":"Athletic performance enhancement","description":"Non-medical use for muscle building is illegal and unsafe; not recommended.","evidence":"Not medically supported"}]

Primary treatment for: Anaemia of chronic kidney disease

Also treats: Osteoporosis, HIV wasting syndrome, Hereditary angioedema

📋 Drug Information

Generic Name(s)Nandrolone Decanoate
Brand NameAlkem Nandrolone 50mg Injection
ManufacturerAlkem Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassAnabolic steroid
Route of AdministrationIntramuscular injection only. Administer deep into the gluteal muscle by a healthcare professional
StorageStore at room temperature (15-30°C), protected from light. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer this medicine only under the supervision of a specialist; never self-inject.
2
Monitor liver function, lipid profile, and blood counts regularly during treatment.
3
Advise patients to avoid alcohol and other hepatotoxic drugs.
4
Watch for signs of virilisation in women and discontinue if they occur.
5
In men, monitor for prostate changes and consider PSA testing.
6
Do not use for athletic performance enhancement; it is illegal and unsafe.
7
Ensure adequate hydration and monitor blood pressure at each visit.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Chronic anaemia in kidney disease
This medicine may be prescribed for this condition.
Likely Use
Severe osteoporosis
May be used as an adjunct in selected patients.
Likely Use
Muscle weakness
Not a primary treatment for general muscle weakness.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSlowly absorbed from the intramuscular depot; peak plasma levels occur after several days.
DistributionWidely distributed in the body, with high concentrations in muscle, liver, and fat tissue.
Protein BindingNandrolone binds mainly to sex hormone-binding globulin (SHBG) and albumin.
MetabolismMetabolised in the liver by reduction and conjugation; some conversion to oestradiol occurs.
Half-LifeThe elimination half-life of nandrolone decanoate is approximately 6 to 12 days after intramuscular injection.
ExcretionExcreted primarily in urine as conjugated metabolites, with a small amount in faeces.
BioavailabilityNot applicable for intramuscular route; systemic availability is complete but slow.
Onset of ActionAnabolic effects may take 2 to 4 weeks to become noticeable.
Peak Plasma TimePeak plasma concentration occurs about 3 to 7 days after injection.
Duration of ActionEffects can last for 2 to 3 weeks after a single injection.

How It Works

Nandrolone decanoate is an esterified anabolic-androgenic steroid. After intramuscular injection, it is slowly hydrolysed to release nandrolone, which binds to androgen receptors in target tissues. This binding activates gene transcription, leading to increased protein synthesis, nitrogen retention, and erythropoietin production. The anabolic effects promote muscle growth and bone matrix formation, while androgenic effects are relatively weaker than testosterone.

Mechanism Steps

1
Intramuscular depot formation: After injection, the oil-based solution forms a depot in the muscle, from which the drug is slowly released.
2
Ester hydrolysis: Nandrolone decanoate is hydrolysed by esterases to free nandrolone, the active hormone.
3
Androgen receptor binding: Free nandrolone enters cells and binds to cytoplasmic androgen receptors.
4
Gene transcription: The hormone-receptor complex moves to the nucleus and regulates gene expression, increasing protein synthesis.
5
Anabolic and erythropoietic effects: This leads to increased muscle protein, bone formation, and red blood cell production.

💡 How to Take alkem nandrolone 50mg injection

Strength: 50 mg/mL injection in a 1 mL ampoule or vial.

1This medicine is given by a healthcare professional as an intramuscular injection.
2It is usually injected into the upper outer quadrant of the buttock.
3Do not self-administer; improper injection can cause nerve damage or infection.
4The injection site should be rotated to prevent irritation.
5Follow your doctor's schedule for injections and monitoring tests.

Dosage Information

Adult DosageThe usual adult dose for anaemia of chronic kidney disease is 50-100 mg per week by intramuscular injection. For osteoporosis, 50 mg every 3 weeks may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to side effects. Use with caution and monitor closely.
Renal ImpairmentNo specific dose adjustment is established, but use with caution in renal impairment and monitor renal function.
Hepatic ImpairmentContraindicated in severe liver disease. In mild to moderate impairment, use with caution and monitor liver function.
Maximum Daily DoseNot applicable; dosing is intermittent (weekly or every 3 weeks).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
No specific timing
This medicine is given by injection, so food timing does not affect it.
Alcohol
Avoid
Increases risk of liver toxicity.
High-sodium foods
Limit
May worsen fluid retention.

⏰ What to Do If You Miss a Dose

📌 You miss a scheduled injection
→ Contact your healthcare provider as soon as possible.
💡 Do not attempt to self-administer a double dose.
📌 You are late by a few days
→ Your doctor may adjust the schedule; follow their advice.
💡 Do not change the frequency without medical guidance.

⚠️ Side Effects of alkem nandrolone 50mg injection

✅ Common Side Effects

Injection site pain (Common (up to 10%))
Apply a cold pack and avoid rubbing the area. Consult if pain persists.
Acne (Common (5-10%))
Keep skin clean; consult a dermatologist if severe.
Fluid retention (Common (5-10%))
Reduce salt intake; report sudden weight gain or swelling.
Increased blood pressure (Uncommon (1-5%))
Monitor blood pressure regularly; consult doctor if persistently high.

🚨 Serious Side Effects

Liver toxicity (Rare (<1%))
Seek immediate medical attention if you notice yellowing of eyes or skin, dark urine, or severe abdominal pain.
Blood clots (Rare (<1%))
Go to emergency if you have chest pain, shortness of breath, or swelling in one leg.
Heart failure worsening (Rare (<1%))
Report sudden weight gain, swelling, or difficulty breathing immediately.
Severe allergic reaction (Very rare (<0.1%))
Call emergency services if you develop rash, itching, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Priapism
Seek emergency care if you have a painful, prolonged erection.
Mood disturbances
Consult your doctor if you experience depression, aggression, or mood swings.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Insulin Moderate
Methotrexate Major
Corticosteroids Moderate
Cyclosporine Moderate

🚨 Major Interactions

  • Warfarin
  • Insulin and oral antidiabetics
  • Hepatotoxic drugs (e.g., methotrexate, isoniazid)

⚡ Moderate Interactions

  • Corticosteroids
  • Cyclosporine

🍷 Alcohol Interaction

Alcohol should be avoided while using this medicine because it increases the risk of liver damage and may worsen fluid retention and blood pressure.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy or breastfeeding","Known hypersensitivity to nandrolone or any component","Male breast cancer or prostate cancer","Severe liver disease","Nephrotic syndrome","Hypercalcaemia"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease, hypertension, or history of blood clots.","May worsen sleep apnoea; monitor if symptoms occur.","Can cause virilisation in women; discontinue if signs appear.","May suppress natural testosterone production in men.","Not for use in children; may cause premature closure of growth plates.","Avoid in athletes; banned by sports authorities."]

🤱 Lactation Safety

Not recommended during breastfeeding because it may pass into breast milk and affect the infant.

💊 Overdose Management

Overdose may cause severe fluid retention, hypertension, and liver toxicity. Treatment is supportive and symptomatic. Seek immediate medical attention. There is no specific antidote.

⏰ Missed Dose

If you miss a scheduled injection, contact your healthcare provider. Do not double the dose to catch up.

Additional Safety Advice

General Safety

This medicine must only be given by a healthcare professional as an intramuscular injection. Do not self-inject or share needles. Inform your doctor if you have heart, liver, kidney, or prostate problems, high blood pressure, diabetes, or a history of blood clots. Regular blood tests for liver function, cholesterol, and blood counts are needed during treatment. Avoid alcohol and other liver-damaging medicines. Do not use this medicine for bodybuilding or athletic performance. Women who are pregnant or planning pregnancy must not use this medicine. Report any unusual swelling, breathing difficulty, chest pain, or yellowing of eyes immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to fluid retention, hypertension, and cardiac effects. Use with caution and monitor closely. Dose adjustment may be needed based on renal and hepatic function.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy and in women planning to conceive. It can harm the fetus. Women of childbearing potential should use effective contraception during treatment and for at least 3 months after stopping.

🏥 Post-Surgery Considerations

This medicine may increase the risk of blood clots after surgery. Inform your surgeon if you are taking it. It may need to be stopped before elective surgery as advised by your doctor.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may affect bleeding and healing. No specific precautions are established, but your dentist may consult your doctor.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on joints and heart.
🥗
Engage in regular low-impact exercise such as walking or swimming.
😴
Avoid alcohol and smoking to protect your liver and heart.
💧
Follow a balanced diet rich in fruits, vegetables, and lean protein.
🧘
Get adequate sleep to support overall health.
🌞
Stay hydrated unless your doctor advises fluid restriction.

🏋️ Exercise Considerations

Avoid strenuous or contact sports while on this medicine, especially if you have bone or joint problems. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce processed and high-sodium foods.
Eat plenty of fruits and vegetables.
Choose lean protein sources.
Limit sugary drinks and snacks.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not interfere with most office work, but discuss any physical job requirements with your doctor.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience serious side effects such as jaundice, chest pain, or severe allergic reactions, seek immediate medical attention and your doctor will decide whether to discontinue.

📅 Long-Term Use Effects

Long-term use of nandrolone decanoate can lead to liver toxicity, cardiovascular problems, and suppression of natural hormone production. Regular monitoring of liver function, lipid profile, and blood counts is essential. The need for continued treatment should be reassessed periodically by a specialist.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Erythropoiesis-stimulating agents (ESAs)

Used for anaemia in chronic kidney disease as an alternative to nandrolone.

Evidence: Well-established
Bisphosphonates

First-line treatment for osteoporosis; nandrolone may be used as adjunct.

Evidence: Well-established
Physical therapy

Can help improve muscle strength and mobility in muscle-wasting conditions.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, patients with chronic kidney disease should follow recommended vaccination schedules, including hepatitis B and influenza vaccines, as advised by their doctor.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate or freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription and a letter from your doctor explaining the medical need, especially when travelling internationally. Store at room temperature and protect from light. Do not pack in checked luggage if refrigeration is not required; keep in carry-on. Be aware that anabolic steroids are controlled substances in many countries, so check local regulations before travel.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with chronic kidney disease and anaemia
He received weekly nandrolone decanoate injections under specialist care. After 8 weeks, his haemoglobin improved and he felt less fatigued. He was monitored for liver and kidney function throughout.
💡 Lesson: Regular monitoring and adherence to the prescribed schedule are essential for safe and effective treatment.
👤 A 62-year-old postmenopausal woman with severe osteoporosis
She was prescribed nandrolone decanoate every 3 weeks as an adjunct to calcium and vitamin D. Her bone density improved over 6 months, but she developed mild voice deepening, which resolved after stopping the medicine.
💡 Lesson: Women should report any voice changes or increased hair growth immediately, as these may be signs of virilisation.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Anabolic effects may take 2 to 4 weeks to become noticeable, while improvements in anaemia may take 6 to 8 weeks.

Q: Is this medicine safe for women?

A: It can cause virilising effects in women, such as voice deepening and increased hair growth. It should only be used under specialist supervision.

Q: Can I stop the injections if I feel better?

A: Do not stop without consulting your doctor. Stopping suddenly may cause a return of symptoms.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for alkem nandrolone 50mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Nandrolone decanoate is a safe bodybuilding supplement.
    Fact: It is a prescription medicine with serious risks and is illegal for non-medical use.
  • Myth: It can be self-injected safely.
    Fact: It must be given by a healthcare professional to avoid infection and injury.

🔄 Alternative Options

Generic Alternatives

  • Nandrolone decanoate 50 mg/mL injection (generic)

Brand Alternatives

  • Deca-Durabolin
  • Nandrobolin
  • Nandrolone Decanoate Injection

📊 Comparison with Similar Medicines

[{"medicine":"Nandrolone decanoate","class":"Anabolic steroid","route":"Intramuscular","half_life":"6-12 days","main_use":"Anaemia, osteoporosis"},{"medicine":"Testosterone enanthate","class":"Anabolic steroid","route":"Intramuscular","half_life":"4-5 days","main_use":"Hypogonadism"}]

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