Valsartan + Hydrochlorothiazide 80 mg/12.5 mg Tablet: Complete Guide
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Decreased urine output or swelling in legs
- Irregular heartbeat or palpitations
- Severe allergic reaction (rash, itching, swelling of face/lips/throat, difficulty breathing)
- Severe abdominal pain with nausea and vomiting
- Yellowing of skin or eyes
- Unusual muscle weakness or cramps
- Confusion or extreme fatigue
If experiencing severe symptoms, call emergency services immediately.
What is valfect h 80mg/12.5mg tablet used for?
This medicine is a combination of Valsartan and Hydrochlorothiazide used to treat high blood pressure. It works by relaxing blood vessels and removing excess fluid from the body. It is taken orally once daily, usually with or without food. Regular monitoring of blood pressure, kidney function, and electrolytes is important.
- Generic Name: Valsartan (80mg) + Hydrochlorothiazide (12.5mg)
- Manufacturer: AstraZeneca
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 valfect h 80mg/12.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें वैल्सार्टन और हाइड्रोक्लोरोथियाजाइड दो सक्रिय तत्व होते हैं जो मिलकर रक्तचाप को कम करने में मदद करते हैं। वैल्सार्टन रक्त वाहिकाओं को आराम देता है और हाइड्रोक्लोरोथियाजाइड शरीर से अतिरिक्त नमक और पानी को बाहर निकालता है। यह दवा आमतौर पर दिन में एक बार मुँह से ली जाती है। इसे डॉक्टर की सलाह के अनुसार ही लें और बिना पूछे बंद न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान और जी मिचलाना शामिल हैं। कुछ लोगों में पेशाब बार-बार आना, प्यास लगना और इलेक्ट्रोलाइट असंतुलन हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज ब्लड प्रेशर गिरना, किडनी की समस्या और एलर्जी प्रतिक्रिया शामिल हो सकती है। अगर आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक बदलें या दवा बंद करने से पहले डॉक्टर से सलाह लें। इस दवा से चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने से बचें जब तक आपको पता न चल जाए कि यह आप पर कैसा असर करती है। पर्याप्त पानी पिएं। शराब से बचें क्योंकि इससे चक्कर और ब्लड प्रेशर कम हो सकता है। अगर आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं तो तुरंत डॉक्टर को बताएं। नियमित रूप से किडनी फंक्शन और इलेक्ट्रोलाइट्स की जांच कराएं।
💊 valfect h 80mg/12.5mg tablet Uses & Benefits
- [{"condition":"Hypertension","description":"Used to lower high blood pressure in adults when a single agent is insufficient.
- It reduces the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"}]
Off-label uses: []
Primary treatment for: Hypertension
Also treats: Heart failure (with reduced ejection fraction), Diabetic nephropathy
📋 Drug Information
| Generic Name(s) | Valsartan (80mg) + Hydrochlorothiazide (12.5mg) |
| Brand Name | valfect h 80mg/12.5mg tablet |
| Manufacturer | AstraZeneca |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Valsartan selectively blocks the angiotensin II type 1 (AT1) receptor, preventing angiotensin II from exerting its vasoconstrictor and aldosterone-secreting effects. This leads to vasodilation, reduced aldosterone release, and decreased sodium and water retention. Hydrochlorothiazide inhibits the reabsorption of sodium and chloride in the distal convoluted tubule of the kidney, increasing excretion of sodium, chloride, and water. This diuretic effect reduces plasma volume and, over time, lowers peripheral vascular resistance. The combination produces a greater reduction in blood pressure than either agent alone.
Mechanism Steps
💡 How to Take valfect h 80mg/12.5mg tablet
Strength: Tablet containing Valsartan 80 mg and Hydrochlorothiazide 12.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Valsartan 80 mg + Hydrochlorothiazide 12.5 mg) taken orally once daily. The dose may be adjusted by your doctor based on your blood pressure response and tolerability. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and monitor closely for dizziness and falls. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with mild to moderate kidney impairment, no dose adjustment is usually needed. However, in severe kidney impairment (eGFR <30 mL/min/1.73 m²), this medicine is not recommended. Consult your doctor for dose adjustments. |
| Hepatic Impairment | In patients with mild to moderate liver impairment, no dose adjustment is needed. However, in severe liver impairment, this medicine is contraindicated. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Valsartan 80 mg + Hydrochlorothiazide 12.5 mg) once daily. Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of valfect h 80mg/12.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Potassium-sparing diuretics | Major | |
| Lithium | Major | |
| NSAIDs | Major | |
| Corticosteroids | Moderate | |
| Diabetes medications | Moderate | |
| Cholestyramine | Moderate | |
| Antacids | Minor | |
| Carbamazepine | Minor |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone, triamterene)
- Lithium
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
⚡ Moderate Interactions
- Corticosteroids
- Diabetes medications (e.g., insulin, oral hypoglycemics)
- Cholestyramine and colestipol
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and increased risk of fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy","Anuria (absence of urine production)","Hypersensitivity to valsartan, hydrochlorothiazide, or sulfonamide-derived drugs","Severe kidney disease (eGFR
⚠️ Warnings & Precautions
["This medicine can cause fetal harm when administered to a pregnant woman. Discontinue as soon as pregnancy is detected.","May cause symptomatic hypotension, especially in volume-depleted patients. Correct volume depletion before starting therapy.","Hydrochlorothiazide can cause electrolyte imbalances. Monitor electrolytes regularly.","May worsen kidney function. Monitor kidney function periodically.","Can cause dizziness; avoid driving or operating machinery until you know how it affects you.","Avoid alcohol as it may enhance hypotensive effects.","Do not use potassium supplements or salt substitutes without medical advice.","May increase blood sugar levels; monitor glucose in diabetic patients.","May cause photosensitivity; use sun protection.","Not recommended for patients with a history of angioedema related to ACE inhibitors or ARBs."]
🤱 Lactation Safety
Hydrochlorothiazide is excreted in breast milk and may cause decreased milk production. Valsartan is also present in breast milk. This medicine is not recommended during breastfeeding. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose may cause severe hypotension, electrolyte imbalances, and dehydration. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including induction of vomiting if recent ingestion, administration of activated charcoal, and intravenous fluids for hypotension. Monitor vital signs, electrolytes, and kidney function closely.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your healthcare provider. This medicine can cause dizziness; avoid driving or operating heavy machinery until you know how it affects you. Stand up slowly from a sitting or lying position to prevent falls. Drink adequate fluids to stay hydrated, especially if you experience increased urination. Avoid alcohol, as it can worsen dizziness and low blood pressure. Inform your doctor if you have kidney disease, liver disease, diabetes, or gout. Regular blood tests to monitor kidney function, potassium, and sodium levels are important. Do not use potassium supplements or salt substitutes containing potassium without your doctor's approval. If you become pregnant, contact your doctor immediately, as this medicine can harm the unborn baby. Keep this medicine out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of dizziness and falls. Start with a lower dose and monitor closely. Regular monitoring of kidney function and electrolytes is especially important.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy as it can harm the fetus. If you are planning pregnancy, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery due to the risk of hypotension. Follow your doctor's instructions regarding when to resume.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or dizziness during dental procedures. Maintain good oral hygiene. Your dentist may need to take precautions if you require local anesthesia with epinephrine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe and beneficial while taking this medicine. However, avoid strenuous activities that may cause dehydration or excessive sweating, as this can lead to low blood pressure and dizziness. Stay hydrated during exercise. If you experience dizziness or shortness of breath, stop and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, especially when standing up quickly. Avoid driving or operating heavy machinery until you know how it affects you. It is usually safe to continue your daily work activities, but take precautions if you feel lightheaded. Inform your employer if your job involves operating machinery or working at heights.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or become pregnant, contact your doctor immediately. Your doctor may adjust the dose or switch to a different medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to electrolyte imbalances, kidney function changes, and increased blood sugar levels. Regular monitoring of blood pressure, kidney function, electrolytes, and blood glucose is essential. It is important to continue lifestyle modifications such as a low-salt diet and regular exercise. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedACE inhibitors, calcium channel blockers, or beta-blockers may be alternatives if this medicine is not suitable.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, consult your doctor about adjusting the timing of your dose. Carry enough supply for the entire trip. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 2-4 hours, but maximum effect may take 2-4 weeks of regular use.
A: It can be taken at any time of day, but taking it at night may cause increased urination and disturb sleep. Consult your doctor for the best timing.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause a dangerous rise in blood pressure.
A: This medicine may cause mild weight loss due to its diuretic effect, but it is not intended for weight loss. Consult your doctor if you experience significant weight changes.
🤔 Common Patient Concerns
🔄 Substitutes for valfect h 80mg/12.5mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia valsartan+hydrochlorothiazide 80mg/12.5mg tabletDavaindia Generic Pharmacy ₹22.00 78.8% CHEAPER
-
valent-h tabletLupin Ltd ₹191.40 84% COSTLIER
-
valembic h 80mg/12.5mg tabletAlembic Pharmaceuticals Ltd ₹193.92 86.5% COSTLIER
-
valzaar-h tabletTorrent Pharmaceuticals Ltd ₹441.00 324% COSTLIER
-
co-diovan 80/12.5 tabletNovartis India Ltd ₹839.00 706.7% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause a dangerous rise in blood pressure. - Myth: This medicine damages the kidneys.
Fact: When used appropriately and monitored, this medicine helps protect the kidneys, especially in diabetic patients. However, kidney function should be monitored regularly. - Myth: Taking this medicine means I can eat whatever I want.
Fact: A healthy diet low in salt and rich in fruits and vegetables is essential for controlling blood pressure and reducing the risk of complications.
🔄 Alternative Options
Generic Alternatives
- Valsartan + Hydrochlorothiazide (generic versions available from various manufacturers)