Anoflox TZ 200mg/600mg Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Sudden tendon pain or swelling
- Numbness or tingling in hands or feet
- Seizures or confusion
If experiencing severe symptoms, call emergency services immediately.
What is upton ct 200mg/600mg tablet used for?
This medicine is a combination antibiotic containing Ofloxacin 200 mg and Tinidazole 600 mg. It is used to treat bacterial and protozoal infections, especially amoebic dysentery and giardiasis. It works by killing the microorganisms causing the infection. It is a prescription medicine and must be taken exactly as directed by your doctor.
- Generic Name: Ofloxacin (200mg) + Tinidazole (600mg)
- Manufacturer: Medicamen Biotech Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 upton ct 200mg/600mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन और टिनिडाजोल का संयोजन है, जिसका उपयोग बैक्टीरियल और प्रोटोज़ोअल संक्रमणों के इलाज के लिए किया जाता है। यह मुख्य रूप से आंत्रशोथ (अमीबिक डिसेंट्री), जिआर्डिया संक्रमण, और पेट के कुछ संक्रमणों में प्रभावी है। यह दवा कीटाणुओं को मारकर संक्रमण को ठीक करती है। इसे डॉक्टर के निर्देशानुसार ही लें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और मुँह में धातु जैसा स्वाद शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि आपको एलर्जी, टेंडन में दर्द, झुनझुनी, दौरे, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे दूसरों के साथ साझा न करें। उपचार के दौरान और आखिरी खुराक के 72 घंटे बाद तक शराब बिल्कुल न लें, क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है। पर्याप्त पानी पिएं। यदि आपको चक्कर आते हैं तो वाहन न चलाएँ। यदि आपको गुर्दे या यकृत की समस्या, मिर्गी, या टेंडन की समस्या है तो डॉक्टर को बताएं। पूरा कोर्स पूरा करें।
💊 upton ct 200mg/600mg tablet Uses & Benefits
[{"condition":"Amoebic dysentery","description":"This medicine is used to treat intestinal amoebiasis caused by Entamoeba histolytica, helping to resolve diarrhea, abdominal pain, and bloody stools.","evidence":"Well-established"},{"condition":"Giardiasis","description":"It is effective against Giardia lamblia infection, which causes diarrhea, bloating, and malabsorption.","evidence":"Well-established"},{"condition":"Bacterial gastroenteritis","description":"It may be prescribed for certain bacterial causes of gastroenteritis when susceptible organisms are involved.","evidence":"Moderate"},{"condition":"Intra-abdominal infections","description":"Used in some cases of intra-abdominal infections, often as part of a broader treatment plan.","evidence":"Moderate"},{"condition":"Trichomoniasis","description":"Tinidazole component is effective against Trichomonas vaginalis, though this combination is not the first-line for this infection.","evidence":"Limited"}]
Off-label uses: [{"condition":"Bacterial vaginosis","description":"Tinidazole may be used off-label for bacterial vaginosis, but this combination is not standard.","evidence":"Limited"},{"condition":"Helicobacter pylori eradication","description":"Ofloxacin is sometimes included in second-line regimens for H. pylori, but this specific combination is not standard.","evidence":"Limited"}]
Primary treatment for: Amoebic dysentery
Also treats: Giardiasis, Bacterial gastroenteritis, Intra-abdominal infections, Trichomoniasis
📋 Drug Information
| Generic Name(s) | Ofloxacin (200mg) + Tinidazole (600mg) |
| Brand Name | upton ct 200mg/600mg tablet |
| Manufacturer | Medicamen Biotech Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a tightly closed container, away from light and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antimicrobial agents with different mechanisms. Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, repair, and recombination, leading to bacterial cell death. Tinidazole is a prodrug that is reduced by ferredoxin in anaerobic organisms and protozoa, generating reactive cytotoxic intermediates that damage DNA and inhibit nucleic acid synthesis, resulting in cell death.
Mechanism Steps
💡 How to Take upton ct 200mg/600mg tablet
Strength: Each tablet contains Ofloxacin 200 mg and Tinidazole 600 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally twice daily, or as prescribed by your doctor. The exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and other factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-medicate or change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more susceptible to side effects such as tendon rupture, CNS effects, and renal impairment. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely. |
| Renal Impairment | Dose adjustment is required in patients with renal impairment. For creatinine clearance less than 50 mL/min, the dose may need to be reduced or the dosing interval increased. Consult your doctor for specific recommendations. |
| Hepatic Impairment | No specific dose adjustment is established for hepatic impairment, but use with caution and monitor liver function. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet twice daily (Ofloxacin 400 mg + Tinidazole 1200 mg). Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of upton ct 200mg/600mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Theophylline | Major | |
| Antacids (Al/Mg) | Major | |
| Sucralfate | Major | |
| Iron supplements | Major | |
| Zinc supplements | Major | |
| Didanosine | Major | |
| Corticosteroids | Major | |
| NSAIDs | Major | |
| Alcohol | Major |
🚨 Major Interactions
- Warfarin
- Theophylline
- Antacids containing aluminum or magnesium
- Sucralfate
- Iron supplements
- Zinc supplements
- Didanosine
- Corticosteroids
- NSAIDs
- Alcohol
⚡ Moderate Interactions
- Caffeine
- Cyclosporine
- Probenecid
- Oral hypoglycemics
- Phenytoin
🍷 Alcohol Interaction
Alcohol must be completely avoided while taking this medicine and for at least 72 hours after the last dose. The tinidazole component can cause a disulfiram-like reaction with alcohol, leading to severe nausea, vomiting, flushing, headache, and rapid heartbeat. Additionally, alcohol may worsen dizziness and drowsiness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ofloxacin, tinidazole, other fluoroquinolones, or nitroimidazoles","History of tendon disorders related to fluoroquinolone use","Myasthenia gravis","Pregnancy (especially first trimester) unless clearly needed","Breastfeeding","Children under 18 years (unless specifically prescribed)","Severe renal impairment (dose adjustment required)","Epilepsy or other seizure disorders (use with caution)","Alcohol use during treatment and for 72 hours after"]
⚠️ Warnings & Precautions
["Fluoroquinolones can cause tendon inflammation and rupture, especially in older adults, those with kidney disease, and those on corticosteroids. Stop the medicine and rest if tendon pain occurs.","May cause peripheral neuropathy. Report numbness, tingling, or weakness immediately.","Can cause CNS effects including seizures, confusion, and hallucinations. Use with caution in patients with CNS disorders.","May exacerbate myasthenia gravis. Avoid in these patients.","Serious skin reactions have been reported. Discontinue at first sign of rash.","Avoid excessive sunlight and use sunscreen due to photosensitivity risk.","May cause hypoglycemia in diabetic patients. Monitor blood sugar closely.","Do not use in patients with a history of tendon disorders with fluoroquinolones.","Complete the full course to prevent resistance.","Avoid alcohol completely during and for 72 hours after treatment."]
🤱 Lactation Safety
This medicine is excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made to discontinue nursing or discontinue the medicine, taking into account the importance of the medicine to the mother.
💊 Overdose Management
There is no specific antidote for overdose with this medicine. Treatment should be symptomatic and supportive. Maintain adequate hydration to prevent crystalluria. Monitor renal and hepatic function. In case of overdose, seek immediate medical attention.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not share it with others. Avoid alcohol completely during treatment and for at least 72 hours after the last dose, as it can cause a severe reaction. Drink plenty of water to stay hydrated. Do not drive or operate heavy machinery if you feel dizzy. Inform your doctor if you have kidney or liver problems, epilepsy, or a history of tendon problems. Complete the full course even if you feel better. Store in a cool, dry place away from direct sunlight.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, peripheral neuropathy, CNS effects, and renal impairment. Dose adjustment may be needed based on kidney function. Use with caution and monitor closely for any adverse effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. It is not recommended during pregnancy, especially in the first trimester, due to potential risks to the fetus. Use effective contraception during treatment and for at least 72 hours after the last dose.
🏥 Post-Surgery Considerations
This medicine may be prescribed after certain abdominal surgeries to prevent or treat infections. Follow your surgeon's instructions carefully. Inform your surgeon if you have any tendon disorders or kidney problems before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may interact with certain antibiotics or anesthetics. Your dentist may recommend postponing elective procedures until you complete the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you experience dizziness, fatigue, or joint pain. If you notice any tendon pain, stop exercising and consult your doctor immediately.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or confusion in some people. Avoid driving, operating heavy machinery, or performing tasks that require mental alertness until you know how it affects you. Take sick leave if you have severe diarrhea or fatigue to allow proper rest and recovery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. However, if you experience serious side effects such as tendon pain, severe allergic reaction, seizures, or signs of liver damage, stop the medicine and seek immediate medical attention.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended and may lead to antibiotic resistance, fungal overgrowth, and rare but serious effects such as peripheral neuropathy, tendon damage, and liver toxicity. It should only be used for the prescribed duration. If prolonged therapy is necessary, your doctor will monitor your blood counts, liver and kidney function, and neurological status.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Essential for managing dehydration caused by diarrhea, alongside antibiotics.
Evidence: Well-establishedMay help restore gut flora and reduce antibiotic-associated diarrhea.
Evidence: ModerateCan reduce duration and severity of diarrhea in some cases.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, live vaccines should be avoided during antibiotic therapy as the antibiotic may reduce vaccine efficacy. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing times gradually to maintain even intervals. Check local customs regulations for carrying prescription medicines. Always carry enough for your entire trip and a little extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 1-2 days, but it is important to complete the full course as prescribed to ensure the infection is fully cleared.
A: Yes, take it with food to reduce stomach upset. However, avoid taking it with dairy products, antacids, or iron/zinc supplements within 2 hours.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, alcohol must be completely avoided during treatment and for at least 72 hours after the last dose, as it can cause a severe reaction.
A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor for safer alternatives.
A: Store at room temperature between 15°C and 30°C, away from light and moisture. Keep in the original container.
🤔 Common Patient Concerns
🔄 Substitutes for upton ct 200mg/600mg tablet
View AllAlternative brands with exact same active ingredient:
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oflochem tz syrupBiochem Pharmaceutical Industries ₹11.83 78.5% CHEAPER
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oflotas tz syrupIntas Pharmaceuticals Ltd ₹12.89 76.6% CHEAPER
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ofrex tz 200mg/600mg suspensionZydus Cadila ₹20.32 63.1% CHEAPER
-
oxo tz 200mg/600mg tabletInd Swift Laboratories Ltd ₹22.90 58.4% CHEAPER
-
eufox tz 200mg/600mg tabletLupin Ltd ₹23.44 57.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any type of diarrhea.
Fact: This medicine is only effective against specific bacterial and protozoal infections. It is not effective for viral diarrhea or other causes. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance. - Myth: It is safe to drink alcohol while taking this medicine.
Fact: Alcohol must be completely avoided during treatment and for 72 hours after, as it can cause a severe disulfiram-like reaction. - Myth: This medicine is safe for children.
Fact: This medicine is not recommended for children unless specifically prescribed by a pediatrician, as it can affect bone and joint development.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin 200 mg + Tinidazole 600 mg tablet (various manufacturers)
Brand Alternatives
- Ofloxacin 200 mg + Tinidazole 600 mg tablet (generic)