Elicalm SF Tablet: Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- High fever with muscle rigidity and confusion
- Involuntary movements of the face, tongue, or limbs
- Severe dizziness or fainting
- Irregular heartbeat or palpitations
- Yellowing of skin or eyes
- Difficulty swallowing or breathing
- Severe abdominal pain or vomiting blood
- Unusual bruising or bleeding
If experiencing severe symptoms, call emergency services immediately.
What is uno 25mg/2mg/5mg tablet used for?
This medicine is a combination of Chlorpromazine (an antipsychotic) and Trihexyphenidyl (an anticholinergic). It is used to treat schizophrenia and other psychotic disorders, and to prevent or treat movement side effects caused by antipsychotics. It is available as a tablet and is taken orally, usually 2-3 times daily. It can cause drowsiness, dry mouth, and dizziness. It should be used under medical supervision.
- Generic Name: Chlorpromazine (25mg) + Trihexyphenidyl (2mg)
- Manufacturer: Talent Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 uno 25mg/2mg/5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोरप्रोमाज़ीन और ट्राइहेक्सिफेनिडाइल का संयोजन है। इसका उपयोग सिज़ोफ्रेनिया और अन्य मानसिक विकारों के इलाज के लिए किया जाता है। यह मतिभ्रम, भ्रम और आंदोलन को कम करने में मदद करती है। ट्राइहेक्सिफेनिडाइल उन मांसपेशियों की अकड़न और कंपन को कम करता है जो क्लोरप्रोमाज़ीन के कारण हो सकती हैं। यह दवा मतली और उल्टी को नियंत्रित करने में भी मदद करती है। यह केवल डॉक्टर के पर्चे पर मिलती है और डॉक्टर की सलाह के अनुसार ही लेनी चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, कब्ज और पेशाब रोकना शामिल हैं। गंभीर दुष्प्रभावों में मांसपेशियों में अकड़न, कंपन, बुखार, भ्रम, और अनैच्छिक हरकतें शामिल हो सकती हैं। यदि आपको कोई भी असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। दवा की खुराक खुद से न बदलें और न ही अचानक बंद करें। इस दवा को लेने के दौरान वाहन चलाने या मशीनरी चलाने से बचें क्योंकि इससे नींद और चक्कर आ सकते हैं। शराब का सेवन न करें। पर्याप्त पानी पिएं और फाइबर युक्त भोजन करें। यदि आपको ग्लूकोमा, प्रोस्टेट की समस्या, जिगर या दिल की बीमारी है तो डॉक्टर को बताएं। नियमित जांच कराते रहें।
💊 uno 25mg/2mg/5mg tablet Uses & Benefits
- [{"condition":"Schizophrenia","description":"Helps reduce hallucinations, delusions, and disorganized thinking.
- Trihexyphenidyl reduces drug-induced movement side effects.","evidence":"Well-established"},{"condition":"Psychosis with agitation","description":"Controls severe agitation and aggressive behavior in psychotic disorders.","evidence":"Well-established"},{"condition":"Nausea and vomiting","description":"Chlorpromazine has antiemetic properties; used for severe nausea and vomiting.","evidence":"Well-established"},{"condition":"Extrapyramidal symptoms","description":"Trihexyphenidyl treats or prevents drug-induced movement disorders.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Intractable hiccups","description":"Chlorpromazine may be used off-label for persistent hiccups.","evidence":"Limited"},{"condition":"Porphyria","description":"Sometimes used off-label for acute intermittent porphyria.","evidence":"Limited"}]
Primary treatment for: Schizophrenia
Also treats: Psychosis with agitation, Nausea and vomiting, Extrapyramidal symptoms
📋 Drug Information
| Generic Name(s) | Chlorpromazine (25mg) + Trihexyphenidyl (2mg) |
| Brand Name | uno 25mg/2mg/5mg tablet |
| Manufacturer | Talent Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Chlorpromazine blocks postsynaptic dopamine D2 receptors in the mesolimbic and mesocortical pathways, reducing psychotic symptoms. It also has anticholinergic, antihistaminic, and alpha-adrenergic blocking effects. Trihexyphenidyl is a centrally acting anticholinergic that restores the balance between dopamine and acetylcholine in the basal ganglia, thereby reducing extrapyramidal symptoms caused by chlorpromazine.
Mechanism Steps
💡 How to Take uno 25mg/2mg/5mg tablet
Strength: Tablet containing Chlorpromazine 25 mg and Trihexyphenidyl 2 mg.
Dosage Information
| Adult Dosage | The dosage is individualized by a qualified clinician based on the indication, severity of symptoms, age, and renal/hepatic function. For schizophrenia, a typical starting dose is one tablet two to three times daily, but the dose may be adjusted gradually. For nausea and vomiting, a lower dose may be used. Do not exceed the prescribed dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients are more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Monitor for orthostatic hypotension, confusion, and falls. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult a doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose reduction may be required. Monitor liver function. Consult a doctor. |
| Maximum Daily Dose | The maximum daily dose is determined by the prescribing clinician based on the patient's condition and response. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of uno 25mg/2mg/5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Moderate | |
| Fluoxetine | Moderate | |
| Carbamazepine | Moderate | |
| Lithium | Moderate | |
| Propranolol | Moderate | |
| Phenytoin | Moderate | |
| Ritonavir | Major | |
| Ketoconazole | Moderate | |
| Anticholinergics | Major | |
| Levodopa | Major |
🚨 Major Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Anticholinergic drugs (e.g., atropine, antihistamines)
- Levodopa
- MAO inhibitors
⚡ Moderate Interactions
- Antihypertensives
- Metoclopramide
- Tricyclic antidepressants
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase sedation, dizziness, and respiratory depression, and may worsen antipsychotic side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpromazine, trihexyphenidyl, or any component","Glaucoma (narrow-angle)","Urinary retention (e.g., due to prostatic hypertrophy)","Severe liver disease","Severe cardiovascular disease","Parkinson's disease (trihexyphenidyl may worsen) - but used cautiously for drug-induced EPS","History of neuroleptic malignant syndrome","Bone marrow depression","Coma or severe CNS depression"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery until effects are known.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients; increased risk of falls, confusion, and anticholinergic effects.","May lower seizure threshold; use with caution in patients with epilepsy.","Can cause photosensitivity; use sunscreen and protective clothing.","May impair ability to regulate body temperature; avoid extreme heat.","Long-term use may cause tardive dyskinesia; monitor regularly.","Do not stop abruptly; withdrawal symptoms may occur.","Use with caution in patients with hepatic or renal impairment.","May increase prolactin levels; monitor for galactorrhea, gynecomastia."]
🤱 Lactation Safety
Chlorpromazine is excreted in breast milk and may cause drowsiness in the infant. Trihexyphenidyl may also pass into breast milk. Breastfeeding is not recommended while taking this medicine unless advised by a doctor.
💊 Overdose Management
Overdose can cause severe drowsiness, coma, hypotension, tachycardia, arrhythmias, and extrapyramidal symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs, ECG, and electrolytes. For extrapyramidal symptoms, anticholinergic drugs like benztropine may be used. For hypotension, use fluids and vasopressors if needed. Avoid epinephrine due to paradoxical hypotension.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness and dizziness. Avoid alcohol and other central nervous system depressants while taking this medicine. Drink plenty of water and eat a high-fiber diet to prevent constipation. Inform your doctor if you have glaucoma, prostate problems, liver disease, heart disease, or a history of seizures. Regular monitoring of blood counts, liver function, and eye exams may be required during long-term therapy. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of this medicine. They are at higher risk of orthostatic hypotension, confusion, falls, and anticholinergic effects. Start with a lower dose and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor. This medicine should be used during pregnancy only if clearly needed. Effective contraception is advised while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect blood pressure and heart rate. Your doctor may advise temporary discontinuation before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It can cause dry mouth, which may increase the risk of dental problems. Regular dental check-ups are recommended.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and blurred vision, which may affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also affect your concentration and reaction time.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Abrupt discontinuation can cause withdrawal symptoms such as nausea, vomiting, insomnia, and relapse of psychosis. Your doctor will gradually reduce the dose if needed.
📅 Long-Term Use Effects
Long-term use of this medicine may cause tardive dyskinesia, weight gain, metabolic changes, and eye changes. Regular monitoring of blood counts, liver function, and eye exams is recommended. Periodic assessment of the need for continued therapy is essential.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for managing psychotic symptoms.
Evidence: Well-establishedHelps support the patient and improve treatment adherence.
Evidence: Well-establishedRegular exercise, healthy diet, and stress management can improve overall well-being.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. However, consult your doctor before receiving any live vaccines while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. If traveling across time zones, adjust dosing times gradually under medical advice. Store at room temperature and avoid extreme heat. Check customs regulations for controlled substances before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Sedative effects may begin within 30-60 minutes, but full antipsychotic effects may take several days to weeks.
A: Yes, it can be taken with or without food, but taking it with food may reduce stomach upset.
A: Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, stopping suddenly can cause withdrawal symptoms and relapse. Always consult your doctor before stopping.
A: It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for uno 25mg/2mg/5mg tablet
View AllAlternative brands with exact same active ingredient:
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elicalm sf tabletElite Pharma Pvt Ltd ₹8.44 20.1% COSTLIER
-
reliclam forte 25 mg/2 mg/5 mg tabletReliance Formulation Pvt Ltd ₹13.13 86.8% COSTLIER
-
teem h forte 25mg/2mg/5mg tabletEsteem Pharmaceuticals ₹15.94 126.7% COSTLIER
-
trycalm sf 25 mg/2 mg/5 mg tabletS P Pharma ₹18.03 156.5% COSTLIER
-
triflu sf 25mg/2mg/5mg tabletBiologic Psychotropics India Pvt Ltd ₹28.13 300.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is addictive.
Fact: This medicine is not addictive in the traditional sense, but it can cause dependence and withdrawal symptoms if stopped abruptly. It should be tapered under medical supervision. - Myth: This medicine can cure schizophrenia completely.
Fact: This medicine helps manage symptoms but does not cure schizophrenia. It is part of a comprehensive treatment plan. - Myth: You can stop taking this medicine once you feel better.
Fact: Stopping suddenly can cause withdrawal symptoms and relapse of psychosis. Always consult your doctor before stopping. - Myth: This medicine is safe to take during pregnancy.
Fact: It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor.
🔄 Alternative Options
Generic Alternatives
- Chlorpromazine + Trihexyphenidyl combination tablets from other manufacturers
Brand Alternatives
- Elicalm SF Tablet (Elite Pharma Pvt Ltd)