Exzilor 0.5 mg/10 mg Tablet: Complete Information
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- High fever with muscle rigidity and confusion
- Irregular heartbeat or palpitations
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Involuntary movements of face, tongue, or limbs
- Yellowing of skin or eyes
- Severe dizziness or fainting
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is anxital m 0.5mg/10mg tablet used for?
This medicine is a combination of flupenthixol (an antipsychotic) and melitracen (an antidepressant) used for short-term treatment of anxiety with depression. It works by blocking dopamine receptors and increasing serotonin and norepinephrine levels in the brain.
- Generic Name: Flupenthixol (0.5mg) + Melitracen (10mg)
- Manufacturer: Talent Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 anxital m 0.5mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फ्लूपेंथिक्सोल और मेलिट्रासेन का संयोजन है, जिसका उपयोग चिंता और अवसाद के इलाज के लिए किया जाता है। यह मस्तिष्क में डोपामाइन रिसेप्टर्स को ब्लॉक करके और सेरोटोनिन और नॉरएपिनेफ्रिन के स्तर को बढ़ाकर काम करती है। यह दवा चिंता, तनाव, और अवसाद के लक्षणों को कम करने में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, मुँह सूखना, धुंधली दृष्टि, कब्ज, और चक्कर आना शामिल हैं। गंभीर दुष्प्रभावों में अनियमित दिल की धड़कन, गंभीर एलर्जी प्रतिक्रिया, और न्यूरोलेप्टिक मैलिग्नेंट सिंड्रोम शामिल हो सकते हैं। यदि आपको कोई गंभीर लक्षण महसूस हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। शराब और अन्य नींद लाने वाली दवाओं के साथ इसका सेवन न करें। गाड़ी चलाते समय या मशीन चलाते समय सावधानी बरतें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं जो आप ले रहे हैं। इस दवा को अचानक बंद न करें, क्योंकि इससे withdrawal symptoms हो सकते हैं।
💊 anxital m 0.5mg/10mg tablet Uses & Benefits
[{"condition":"Anxiety with depression","description":"This medicine is used for the short-term treatment of mild to moderate anxiety accompanied by depressive symptoms.","evidence":"Well-established"},{"condition":"Depression","description":"Melitracen component helps improve mood, while flupenthixol may help with associated anxiety and agitation.","evidence":"Moderate"},{"condition":"Psychosomatic disorders","description":"Sometimes used for anxiety and depression associated with physical complaints.","evidence":"Limited"}]
Off-label uses: [{"condition":"Fibromyalgia","description":"May be used off-label for pain and associated anxiety, but evidence is limited.","evidence":"Limited"},{"condition":"Chronic pain with depression","description":"Occasionally prescribed for chronic pain syndromes with depressive features.","evidence":"Limited"}]
Primary treatment for: Anxiety with depression
Also treats: Depression, Psychosomatic disorders
📋 Drug Information
| Generic Name(s) | Flupenthixol (0.5mg) + Melitracen (10mg) |
| Brand Name | anxital m 0.5mg/10mg tablet |
| Manufacturer | Talent Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Flupenthixol is a thioxanthene antipsychotic that blocks dopamine D1 and D2 receptors in the brain, reducing psychotic symptoms and anxiety. Melitracen is a tricyclic antidepressant that inhibits the reuptake of serotonin and norepinephrine, increasing their availability in the synaptic cleft, which helps elevate mood. Together, they address both anxiety and depressive symptoms.
Mechanism Steps
💡 How to Take anxital m 0.5mg/10mg tablet
Strength: Tablet containing flupenthixol 0.5 mg and melitracen 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, as prescribed by your doctor. The dose may be adjusted based on your response and tolerance. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Start with a lower dose and titrate slowly. Monitor for orthostatic hypotension and falls. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 2 tablets (1 mg flupenthixol + 20 mg melitracen). Do not exceed without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of anxital m 0.5mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAO inhibitors | Major | |
| CNS depressants | Major | |
| QT-prolonging drugs | Major | |
| Antihypertensives | Moderate | |
| Anticholinergics | Moderate | |
| Levodopa | Moderate | |
| Antacids | Minor | |
| Caffeine | Minor |
🚨 Major Interactions
- MAO inhibitors
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- QT-prolonging drugs (e.g., amiodarone, sotalol)
⚡ Moderate Interactions
- Antihypertensives
- Anticholinergics
- Levodopa
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and impair judgment, and may worsen depression.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to flupenthixol, melitracen, or any component","Concurrent use with MAO inhibitors","Severe cardiac disease","Pheochromocytoma","Blood dyscrasias","Severe liver disease","Pregnancy and lactation (relative)"]
⚠️ Warnings & Precautions
["May impair ability to drive or operate machinery.","Avoid alcohol and other CNS depressants.","Use with caution in elderly patients.","May lower seizure threshold.","Can cause orthostatic hypotension.","Do not stop abruptly; taper gradually.","May increase risk of falls in elderly."]
🤱 Lactation Safety
Not established from the available information. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose may cause severe drowsiness, coma, cardiac arrhythmias, and extrapyramidal symptoms. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid alcohol and other central nervous system depressants while taking this medicine. Use caution when driving or operating machinery until you know how this medicine affects you. Inform your doctor about all other medications you are taking, especially blood pressure medicines, antidepressants, and antipsychotics. Do not stop this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur. Keep out of reach of children. Store at room temperature away from direct sunlight and moisture.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the sedative and anticholinergic effects of this medicine. Start with a lower dose and monitor for falls, confusion, and orthostatic hypotension.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine in pregnancy is not established, and alternative treatments may be considered.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine, as it may interact with anesthetic agents and increase the risk of complications. It may need to be stopped before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may cause dry mouth and increase the risk of dental problems. It may also interact with local anesthetics.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise until you know how this medicine affects you, as it may cause dizziness or drowsiness. Start with light activities and gradually increase as tolerated.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness and impair concentration, affecting your ability to drive or operate machinery. It is advisable to avoid such activities until you know how it affects you. Discuss with your employer if you need accommodations.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience severe side effects or your condition improves, your doctor may gradually reduce the dose. Abrupt discontinuation can cause withdrawal symptoms such as nausea, headache, and anxiety.
📅 Long-Term Use Effects
Long-term use may increase the risk of tardive dyskinesia and metabolic changes. Regular monitoring of mental status, extrapyramidal symptoms, and metabolic parameters is recommended. Periodic review of the need for continued treatment is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can be effective for anxiety and depression, either alone or in combination with medication.
Evidence: Well-establishedMay help reduce anxiety and improve mood.
Evidence: ModerateCan improve mood and reduce anxiety symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. If traveling across time zones, adjust dosing times gradually to avoid missed doses. Store at room temperature and protect from moisture. Check customs regulations for controlled substances before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Anxiolytic effects may begin within 1-2 hours, but antidepressant effects may take 1-2 weeks.
A: No, you should not stop this medicine abruptly as it can cause withdrawal symptoms. Consult your doctor for a gradual taper.
A: The safety of this medicine in pregnancy is not established. Consult your doctor before taking it if you are pregnant or planning to become pregnant.
🤔 Common Patient Concerns
🔄 Substitutes for anxital m 0.5mg/10mg tablet
View AllAlternative brands with exact same active ingredient:
-
denxol 0.5 mg/10 mg tabletLa Pharmaceuticals ₹32.84 22.2% CHEAPER
-
melcida 0.5mg/10mg tabletDewallace Pharmaceuticals ₹36.56 13.3% CHEAPER
-
relixol 0.5mg/10mg tabletReliance Formulation Pvt Ltd ₹40.18 4.8% CHEAPER
-
duhap 0.5 mg/10 mg tabletTorrent Pharmaceuticals Ltd ₹40.78 3.3% CHEAPER
-
flupen m 0.5mg/10mg tabletLifecare Innovations Pvt Ltd ₹40.95 2.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a sleeping pill.
Fact: This medicine is not a sleeping pill; it is a combination of an antipsychotic and an antidepressant used for anxiety and depression. - Myth: This medicine is addictive.
Fact: This medicine is not considered addictive, but it can cause dependence if used for a long time. It should be tapered gradually. - Myth: I can stop this medicine when I feel better.
Fact: You should not stop this medicine without consulting your doctor, as abrupt discontinuation can cause withdrawal symptoms.
🔄 Alternative Options
Generic Alternatives
- Flupenthixol + Melitracen
Brand Alternatives
- Exzilor 0.5 mg/10 mg Tablet