Ultrabenz Gel: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing.
- Signs of gastrointestinal bleeding: black, tarry stools, vomiting blood, severe abdominal pain.
- Cardiovascular symptoms: chest pain, shortness of breath, weakness in one side of the body.
- Severe skin reaction: blistering, peeling, or intense rash at application site.
- Decreased urine output or swelling in legs, indicating possible kidney problems.
- Yellowing of skin or eyes, indicating liver problems.
- Persistent headache, dizziness, or drowsiness.
If experiencing severe symptoms, call emergency services immediately.
What is ultrabenz gel used for?
This medicine is a topical gel combining cyclobenzaprine (a muscle relaxant) and diclofenac diethylamine (an NSAID) to relieve localized muscle pain, spasm, and inflammation. It is applied directly to the affected area 3-4 times daily for up to 7 days.
- Generic Name: Cyclobenzaprine (2% w/w) + Diclofenac diethylamine (1.16% w/w)
- Manufacturer: Inqor Pharmaceuticals Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ultrabenz gel के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल जेल है जिसमें साइक्लोबेन्ज़ाप्रिन (मांसपेशियों को आराम देने वाला) और डाइक्लोफेनाक डाइएथाइलामाइन (सूजन कम करने वाला) शामिल है। इसका उपयोग मांसपेशियों में दर्द, ऐंठन और सूजन को कम करने के लिए किया जाता है। यह जेल प्रभावित हिस्से पर लगाई जाती है और दर्द से राहत दिलाती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में त्वचा पर जलन, लालिमा, खुजली या सूखापन शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में कठिनाई, या पेट में गंभीर दर्द हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस जेल को केवल बाहरी उपयोग के लिए ही लगाएं। आंखों, मुंह और घाव वाली त्वचा पर न लगाएं। उपयोग के बाद हाथ धो लें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। 7 दिनों से अधिक उपयोग न करें।
💊 ultrabenz gel Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation associated with strains, sprains, and sports injuries.","evidence":"Well-established"},{"condition":"Localized muscle spasm","description":"Helps relax tense muscles and reduce spasm-related discomfort.","evidence":"Well-established"},{"condition":"Myofascial pain syndrome","description":"Provides targeted relief for trigger points and muscle knots.","evidence":"Moderate"},{"condition":"Osteoarthritis of superficial joints","description":"May reduce pain and improve function in joints like knees and hands.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Temporomandibular joint disorder (TMJ)","description":"Sometimes applied over the jaw area for pain relief, but evidence is limited.","evidence":"Limited"},{"condition":"Neuropathic pain","description":"Not typically recommended, but occasionally used for localized neuropathic pain.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain and spasm
Also treats: Osteoarthritis, Myofascial pain syndrome, Sports injuries
📋 Drug Information
| Generic Name(s) | Cyclobenzaprine (2% w/w) + Diclofenac diethylamine (1.16% w/w) |
| Brand Name | ultrabenz gel |
| Manufacturer | Inqor Pharmaceuticals Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Do not freeze. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Cyclobenzaprine acts centrally in the brainstem to reduce tonic somatic motor activity, influencing both gamma and alpha motor neurons, which leads to muscle relaxation. Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins, which are mediators of inflammation and pain. When applied topically, both agents penetrate the skin and exert local effects, with diclofenac primarily reducing inflammation and cyclobenzaprine helping to alleviate muscle spasm.
Mechanism Steps
💡 How to Take ultrabenz gel
Strength: Topical gel containing cyclobenzaprine 2% w/w and diclofenac diethylamine 1.16% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area 3 to 4 times daily, or as directed by your physician. Gently massage into the skin until absorbed. The dose and frequency must be individualized by a qualified clinician based on the indication, severity of symptoms, and patient-specific factors such as age, renal and hepatic function. Do not exceed the recommended frequency or duration of use without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of NSAIDs and cyclobenzaprine. Use with caution and monitor for side effects. Dose adjustment may be necessary based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Topical diclofenac may still carry risks. Consult a doctor for dose adjustment. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Cyclobenzaprine undergoes hepatic metabolism; dose reduction may be needed. Consult a doctor. |
| Maximum Daily Dose | The maximum daily dose for topical application is not well established. Do not exceed the recommended frequency (usually 3-4 times daily) or duration without medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ultrabenz gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| MAOIs | Major | |
| Fluconazole | Moderate | |
| Ketoconazole | Moderate | |
| Lisinopril | Moderate | |
| Topical corticosteroids | Minor | |
| Other topical analgesics | Minor | |
| Aspirin | Moderate | |
| Cimetidine | Minor |
🚨 Major Interactions
- Oral NSAIDs (e.g., ibuprofen, naproxen)
- Anticoagulants (e.g., warfarin)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- CYP2C9 inhibitors (e.g., fluconazole)
- CYP3A4 inhibitors (e.g., ketoconazole)
- Antihypertensives
🍷 Alcohol Interaction
Avoid alcohol while using this medicine. Alcohol can increase the sedative effects of cyclobenzaprine and may also increase the risk of gastrointestinal bleeding associated with diclofenac.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cyclobenzaprine, diclofenac, or any component of the gel","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs","Active peptic ulcer disease or history of recurrent ulcers","Severe renal impairment","Severe hepatic impairment","Third trimester of pregnancy","Use on broken or infected skin","Concurrent use with MAOIs"]
⚠️ Warnings & Precautions
["For external use only. Do not ingest.","Avoid contact with eyes and mucous membranes.","Do not apply to large areas of skin or use for prolonged periods without medical supervision.","Discontinue if severe skin irritation occurs.","Use with caution in patients with cardiovascular risk factors.","Use with caution in elderly patients who may be more susceptible to NSAID effects.","Do not use with occlusive dressings unless directed.","Avoid sun exposure to treated areas.","Keep away from children.","Consult a doctor if symptoms persist beyond 7 days."]
🤱 Lactation Safety
It is not known whether cyclobenzaprine or diclofenac are excreted in human milk after topical application. Systemically, diclofenac is excreted in breast milk in small amounts. Caution is advised. Consult a doctor before use while breastfeeding.
💊 Overdose Management
Overdose with topical gel is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include drowsiness, tachycardia, nausea, vomiting, and gastrointestinal bleeding. Treatment is symptomatic and supportive. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
For external use only. Apply a thin layer to the affected area and gently rub in. Wash hands thoroughly after application unless the hands are the treated area. Avoid contact with eyes, mucous membranes, and broken or irritated skin. Do not cover the treated area with airtight dressings unless directed by a doctor. Do not use with other topical products on the same area without medical advice. Avoid exposure to sunlight or tanning beds on treated skin. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before use. Do not use for more than 7 days without consulting a doctor. Keep out of reach of children. If swallowed, seek medical help immediately.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more susceptible to the systemic effects of NSAIDs and cyclobenzaprine. Use with caution, monitor for side effects, and consider lower frequency of application.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. Avoid use during the third trimester due to potential risks to the fetus.
🏥 Post-Surgery Considerations
Consult your surgeon before using this gel on surgical wounds or nearby areas. It should not be applied to broken skin or incisions.
🦷 Dental Procedures
No specific considerations for dental procedures, but inform your dentist about all medications you are using.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may exacerbate muscle pain while using this medicine. Gentle stretching and low-impact activities are generally safe, but consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is applied topically and is unlikely to affect your ability to drive or operate machinery. However, if you experience drowsiness or dizziness (rare with topical use), avoid these activities until you know how it affects you.
🛑 When to Stop This Medicine
Stop using this medicine and consult a doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any severe side effects such as skin rash, swelling, or signs of systemic reactions.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of systemic side effects such as gastrointestinal bleeding, kidney problems, and cardiovascular events. It is not recommended for prolonged use without medical supervision. Regular monitoring of renal and hepatic function may be advised if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve muscle strength.
Evidence: Well-establishedMay help reduce pain and inflammation locally.
Evidence: ModerateSome evidence for pain relief in musculoskeletal conditions.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medications you are using.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate or freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue application as prescribed; no time adjustment is needed for topical use. Declare it at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Relief may begin within 30-60 minutes, but full effects may take several days of regular use.
A: Consult your doctor before combining with oral NSAIDs, as it may increase the risk of side effects.
A: Pediatric dosing is not established. Consult a pediatrician.
A: Apply as soon as you remember, but if it's almost time for the next dose, skip it. Do not double dose.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: Topical gels are completely safe and have no side effects.
Fact: Topical gels can cause skin irritation and, if absorbed systemically, may lead to NSAID-related side effects. - Myth: You can use this gel indefinitely without consulting a doctor.
Fact: Prolonged use without medical supervision is not recommended. Consult a doctor if symptoms persist beyond 7 days. - Myth: This gel works instantly.
Fact: Relief may begin within 30-60 minutes, but full benefits may take several days of regular use.