Broflez Gel: Complete Guide To Uses, Dosage, And Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe skin reaction (blistering, peeling, or rash) at the application site.
- Signs of allergic reaction: swelling of face, lips, tongue, or throat, difficulty breathing.
- Gastrointestinal bleeding: black, tarry stools or vomiting blood.
- Chest pain, shortness of breath, or irregular heartbeat.
- Sudden severe headache, confusion, or vision changes.
- Decreased urine output or swelling in legs.
- Yellowing of skin or eyes (jaundice).
If experiencing severe symptoms, call emergency services immediately.
What is broflez gel used for?
This medicine is a topical gel combining cyclobenzaprine (a muscle relaxant) and diclofenac diethylamine (an NSAID) to relieve localized muscle pain and spasms. It is applied to the skin 2-3 times daily.
- Generic Name: Cyclobenzaprine (2% w/w) + Diclofenac diethylamine (1% w/w)
- Manufacturer: Broadspectrum Remedies Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 broflez gel के बारे में (Hindi Summary)
उपयोग: यह दवा एक टॉपिकल जेल है जिसमें साइक्लोबेन्ज़ाप्रिन (मांसपेशियों को आराम देने वाला) और डाइक्लोफेनाक डाइएथिलामाइन (सूजन कम करने वाला) शामिल हैं। इसका उपयोग मांसपेशियों में ऐंठन, खिंचाव, और दर्द को कम करने के लिए किया जाता है। यह जेल प्रभावित जगह पर लगाने से मांसपेशियों को आराम मिलता है और सूजन कम होती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में जेल लगाने की जगह पर हल्की जलन, खुजली, या लालिमा शामिल हैं। ये आमतौर पर अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर त्वचा प्रतिक्रिया हो, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस जेल को केवल बाहरी उपयोग के लिए है। आंखों, म्यूकस झिल्ली, और घाव वाली त्वचा पर न लगाएं। उपयोग के बाद हाथ धो लें। 7 दिनों से अधिक उपयोग न करें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों की पहुंच से दूर रखें।
💊 broflez gel Uses & Benefits
[{"condition":"Acute musculoskeletal pain","description":"Relieves pain and inflammation associated with muscle strains, sprains, and other soft tissue injuries.","evidence":"Well-established"},{"condition":"Localized muscle spasms","description":"Helps relax tense muscles and reduce spasm-related pain in conditions such as torticollis or back spasms.","evidence":"Moderate"},{"condition":"Myofascial pain syndrome","description":"Provides symptomatic relief of trigger points and associated muscle pain.","evidence":"Limited"}]
Off-label uses: [{"condition":"Osteoarthritis of superficial joints","description":"May be used off-label for pain relief in osteoarthritis of knees or hands, though not FDA-approved for this indication.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain and muscle spasms
Also treats: Acute strains and sprains, Localized myofascial pain, Torticollis
📋 Drug Information
| Generic Name(s) | Cyclobenzaprine (2% w/w) + Diclofenac diethylamine (1% w/w) |
| Brand Name | broflez gel |
| Manufacturer | Broadspectrum Remedies Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | |
| Route of Administration | Topical |
| Storage | Store at room temperature (15-30°C). Protect from light and moisture. Keep the tube tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Cyclobenzaprine acts centrally in the brainstem to reduce tonic somatic motor activity, thereby decreasing muscle spasm without affecting neuromuscular junction. Diclofenac diethylamine is a nonsteroidal anti-inflammatory drug that inhibits cyclooxygenase enzymes (COX-1 and COX-2), reducing prostaglandin synthesis and thereby decreasing inflammation and pain at the site of application.
Mechanism Steps
💡 How to Take broflez gel
Strength: Gel containing cyclobenzaprine 2% w/w and diclofenac diethylamine 1% w/w.
Dosage Information
| Adult Dosage | Apply a thin layer of this medicine to the affected area 2-3 times daily, or as directed by your doctor. Gently rub in until absorbed. The dose and frequency must be individualized by a qualified clinician based on the condition being treated, age, and other factors. Do not exceed the recommended dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use with caution and follow the doctor's instructions. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose must be individualized by a qualified clinician based on renal function. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose must be individualized by a qualified clinician based on hepatic function. |
| Maximum Daily Dose | Not established from the available information. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of broflez gel
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| MAOIs | Major | |
| Other NSAIDs | Major | |
| CNS depressants | Moderate | |
| Antihypertensives | Moderate | |
| Lithium | Moderate | |
| Topical corticosteroids | Minor | |
| Other topical products | Minor | |
| Grapefruit | Moderate | |
| Alcohol | Moderate |
🚨 Major Interactions
- Oral anticoagulants (e.g., warfarin)
- Other NSAIDs (oral or topical)
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Antihypertensives
- Lithium
🍷 Alcohol Interaction
Avoid alcohol while using this medicine. Alcohol can increase the central nervous system depressant effects of cyclobenzaprine, leading to increased drowsiness and dizziness. Additionally, alcohol may exacerbate the gastrointestinal irritation and bleeding risk associated with diclofenac.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cyclobenzaprine, diclofenac, or any component of the formulation.","History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.","Application to broken or damaged skin.","Use in children under 12 years of age.","Concurrent use with MAOIs or within 14 days of stopping MAOI therapy.","Active peptic ulcer or gastrointestinal bleeding."]
⚠️ Warnings & Precautions
["For external use only. Do not ingest.","Avoid contact with eyes, mucous membranes, and broken skin.","Do not apply to large areas of the body or use with occlusive dressings.","Discontinue use if severe skin reactions occur.","Use with caution in elderly patients due to increased risk of NSAID-related side effects.","Use with caution in patients with cardiovascular risk factors.","Use with caution in patients with gastrointestinal disorders.","Do not use for more than 7 days without medical advice.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether cyclobenzaprine or diclofenac are excreted in human milk after topical application. Because many drugs are excreted in human milk, caution should be exercised when this medicine is used by a nursing woman. Consult your doctor.
💊 Overdose Management
Overdose from topical application is unlikely. If accidental ingestion occurs, seek immediate medical attention. Symptoms of overdose may include drowsiness, dizziness, nausea, vomiting, and gastrointestinal bleeding. Treatment is symptomatic and supportive.
⏰ Missed Dose
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not apply a double dose to make up for a missed one.
Additional Safety Advice
For external use only. Apply a thin layer to the affected area and gently rub in. Wash hands thoroughly after application unless the hands are the treated area. Avoid contact with eyes, mucous membranes, and broken skin. Do not cover the treated area with airtight dressings unless directed by a doctor. Do not use for more than 7 days without consulting a doctor. Keep out of reach of children. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use if you are allergic to cyclobenzaprine, diclofenac, or any other ingredients. Avoid exposure to sunlight or sunlamps on treated areas to prevent photosensitivity reactions. Do not use with other topical products on the same area without medical advice.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of this medicine, especially CNS effects like drowsiness. They are also at higher risk of NSAID-related gastrointestinal and renal side effects. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before using this medicine. NSAIDs like diclofenac may affect ovulation and are generally avoided during pregnancy, especially in the third trimester.
🏥 Post-Surgery Considerations
Consult your surgeon before using this medicine after surgery, as it may increase bleeding risk and interfere with wound healing.
🦷 Dental Procedures
Inform your dentist if you are using this medicine, as diclofenac can increase bleeding risk during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or activities that may exacerbate your condition while using this medicine. Gentle stretching and low-impact exercises may be beneficial, but consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some individuals. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe for office work, but take breaks to stretch and move around.
🛑 When to Stop This Medicine
Stop using this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been using it for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of systemic side effects such as gastrointestinal bleeding, kidney problems, and cardiovascular events due to diclofenac. It is not recommended for extended use without medical supervision. Regular monitoring of kidney and liver function may be advised if used for prolonged periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve muscle strength and flexibility.
Evidence: Well-establishedMay help relieve muscle pain and spasms.
Evidence: ModerateApplying heat packs can relax muscles and reduce pain.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, consult your doctor before vaccination if you are using this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, keep it in its original packaging with the prescription label. Carry a copy of your prescription in case of customs checks. Store at room temperature and protect from extreme heat or cold. If traveling across time zones, continue applying as per your usual schedule, but consult your doctor if you have concerns. Do not leave the gel in a hot car.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling relief within 30-60 minutes of application, but full effects may take several hours to days with regular use.
A: No, this gel is not intended for use on the face or mucous membranes. It should only be applied to the affected area on the body.
A: Consult your doctor before using this medicine during pregnancy. The safety has not been established.
A: Rinse thoroughly with water and seek medical attention if irritation persists.
🤔 Common Patient Concerns
🔄 Substitutes for broflez gel
View AllAlternative brands with exact same active ingredient:
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This gel can be used for any type of pain.
Fact: This gel is specifically for musculoskeletal pain and muscle spasms. It is not effective for headaches or other types of pain. - Myth: More gel means faster relief.
Fact: Applying more than the recommended amount does not improve efficacy and may increase side effects. - Myth: It is safe to use indefinitely.
Fact: This gel should not be used for more than 7 days without medical advice due to potential systemic side effects.
🔄 Alternative Options
Generic Alternatives
- Cyclobenzaprine + Diclofenac topical gel (generic)