Susten 100 Injection: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Sudden shortness of breath or chest pain
- Swelling, pain, or redness in one leg
- Severe headache with vision changes
- Yellowing of skin or eyes
- Severe allergic reaction (rash, swelling of face or throat, difficulty breathing)
- Heavy vaginal bleeding
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is ultigest 100mg/ml injection used for?
This medicine is a progesterone injection used to support pregnancy, treat menstrual disorders, and assist in fertility treatments. It is given by a healthcare professional.
- Generic Name: Progesterone (100mg/ml)
- Manufacturer: Alkem Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ultigest 100mg/ml injection के बारे में (Hindi Summary)
उपयोग: यह दवा प्रोजेस्टेरोन हार्मोन का इंजेक्शन है, जिसका उपयोग गर्भावस्था को सहारा देने, मासिक धर्म की समस्याओं के इलाज और प्रजनन उपचार में किया जाता है। यह केवल डॉक्टर द्वारा दी जाने वाली इंजेक्शन है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन की जगह पर दर्द, सूजन, सिरदर्द, चक्कर आना, स्तनों में कोमलता और मूड में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन खून के थक्के, एलर्जी या लीवर की समस्या हो सकती है। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या स्वास्थ्यकर्मी द्वारा दी जानी चाहिए। खुद से इंजेक्शन न लगाएं। अपने डॉक्टर को सभी दवाओं और स्वास्थ्य समस्याओं के बारे में बताएं। चक्कर आने पर वाहन न चलाएं। नियमित जांच के लिए डॉक्टर के पास जाएं।
💊 ultigest 100mg/ml injection Uses & Benefits
[{"condition":"Luteal phase support in assisted reproduction","description":"This medicine is used to support the luteal phase in women undergoing in vitro fertilization or other assisted reproductive techniques, helping to maintain the uterine lining for embryo implantation.","evidence":"Well-established"},{"condition":"Threatened or recurrent miscarriage due to progesterone deficiency","description":"It may be prescribed to support early pregnancy in women with a history of miscarriage linked to low progesterone levels.","evidence":"Established in selected cases"},{"condition":"Secondary amenorrhea","description":"This medicine can help trigger a menstrual bleed in women whose periods have stopped due to progesterone deficiency.","evidence":"Well-established"},{"condition":"Abnormal uterine bleeding due to hormonal imbalance","description":"It is used to regulate the menstrual cycle when bleeding is caused by a lack of progesterone.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Preterm birth prevention","description":"In some settings, progesterone injections have been used off-label to reduce the risk of preterm birth in women with a short cervix or previous preterm delivery.","evidence":"Limited and debated"},{"condition":"Endometrial hyperplasia","description":"Progesterone may be used off-label to oppose estrogen effects on the uterine lining in selected patients.","evidence":"Limited"}]
Primary treatment for: Progesterone deficiency
Also treats: Infertility, Recurrent miscarriage, Menstrual disorders
📋 Drug Information
| Generic Name(s) | Progesterone (100mg/ml) |
| Brand Name | ultigest 100mg/ml injection |
| Manufacturer | Alkem Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | Natural Progesterone |
| Route of Administration | Parenteral (intramuscular injection) |
| Storage | Store in a cool, dry place, away from direct sunlight. Do not freeze. Keep out of reach of children. |
| Shelf Life | Refer to the packaging for the expiry date. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by delivering progesterone, which binds to progesterone receptors in the nucleus of target cells. This binding activates gene transcription and produces effects that prepare the endometrium for implantation, maintain pregnancy, and regulate the menstrual cycle. It also suppresses the release of gonadotropin-releasing hormone, which can prevent ovulation in certain situations.
Mechanism Steps
💡 How to Take ultigest 100mg/ml injection
Strength: Progesterone 100 mg/ml injection
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the indication, the patient's age, weight, renal and hepatic function, and response to treatment. It is given as an intramuscular injection by a healthcare professional. Common regimens may range from 25 mg to 100 mg or more per day, but the exact dose and frequency must be determined by your doctor. Do not attempt to self-administer. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of progesterone. Dose should be individualized by a clinician, and monitoring for side effects is recommended. |
| Renal Impairment | No specific dose adjustment is established for renal impairment. Use with caution and monitor for side effects. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary based on clinical response and liver function tests. |
| Maximum Daily Dose | The maximum daily dose is determined by the prescribing clinician based on the indication and patient factors. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ultigest 100mg/ml injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ketoconazole | Major | |
| Rifampicin | Major | |
| Insulin | Moderate | |
| Metformin | Moderate | |
| Amlodipine | Moderate | |
| Paracetamol | Minor |
🚨 Major Interactions
- Warfarin
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
- CYP3A4 inducers (e.g., rifampicin, carbamazepine)
⚡ Moderate Interactions
- Diabetes medicines (e.g., insulin, metformin)
- Antihypertensives
🍷 Alcohol Interaction
Alcohol may increase the sedative effects of progesterone and could worsen dizziness or drowsiness. It is advisable to avoid or limit alcohol while receiving this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to progesterone or any ingredient in the injection","Unexplained vaginal bleeding","History of blood clots or thromboembolic disorders","Severe liver disease","Known or suspected breast cancer","Missed abortion"]
⚠️ Warnings & Precautions
["This medicine must be given by a healthcare professional only.","Inform your doctor if you have a history of blood clots, liver disease, kidney disease, asthma, migraine, or epilepsy.","Avoid driving or operating machinery if you feel dizzy or drowsy.","Do not use if you are allergic to progesterone.","Use with caution in patients with diabetes, as it may affect blood sugar control.","Progesterone may cause fluid retention; use with caution in patients with heart or kidney disease."]
🤱 Lactation Safety
Progesterone is present in breast milk. Consult your doctor before using this medicine while breastfeeding. It is generally considered compatible with breastfeeding when used as prescribed.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by a healthcare professional. If accidental overdose occurs, seek immediate medical attention. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, contact your doctor or clinic as soon as possible. Do not try to self-administer an extra dose. Your doctor will advise you on the next step.
Additional Safety Advice
This medicine must be given only by a healthcare professional. Do not attempt to self-inject. Inform your doctor about all medicines you take, especially blood thinners, diabetes medicines, and other hormonal products. Tell your doctor if you have a history of blood clots, liver disease, kidney disease, asthma, migraine, or epilepsy. Avoid driving or operating heavy machinery if you feel dizzy or drowsy after the injection. Do not receive this medicine if you are allergic to progesterone or any of its ingredients. Keep all follow-up appointments so your doctor can monitor your response and adjust treatment if needed.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of progesterone. Close monitoring for side effects is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. It may be prescribed to support conception and early pregnancy in certain cases.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are receiving this medicine before surgery. It may affect blood clotting and fluid balance.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine, especially if you have a history of blood clots or are on blood thinners.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you feel dizzy or fatigued after the injection. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. Inform your employer if your work requires such activities.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Your doctor will advise you on when and how to stop based on your condition and response to treatment.
📅 Long-Term Use Effects
Long-term use of this medicine should be monitored by a doctor. Regular check-ups may include liver function tests and assessment for blood clots. Prolonged use without medical supervision is not recommended.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be an alternative for some indications, but differs in absorption and effects.
Evidence: Well-establishedAnother route of administration for progesterone supplementation.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
If you need to travel while receiving this medicine, carry it in its original packaging with the prescription label. Keep a copy of your prescription with you. Store it at room temperature and protect it from extreme heat or cold. If traveling across time zones, consult your doctor about adjusting the timing of your injections. Declare the medicine at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The effects begin within hours to days, depending on the indication. Your doctor will monitor your response.
A: It is used in pregnancy when prescribed by a doctor. Discuss the risks and benefits with your healthcare provider.
A: No, this medicine must be given by a healthcare professional.
🤔 Common Patient Concerns
🔄 Substitutes for ultigest 100mg/ml injection
View AllAlternative brands with exact same active ingredient:
-
gesterol 100mg/ml injectionNeon Laboratories Ltd ₹80.86 0.3% COSTLIER
-
eugest 100mg/ml injectionSamarth Life Sciences Pvt Ltd ₹111.57 38.4% COSTLIER
-
susten 200 injectionSun Pharmaceutical Industries Ltd ₹276.56 243% COSTLIER
-
susten 100 injectionSun Pharmaceutical Industries Ltd ₹825.00 923.2% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be self-injected at home.
Fact: This medicine must be given by a healthcare professional only. - Myth: This medicine is safe for everyone.
Fact: It is contraindicated in certain conditions such as unexplained vaginal bleeding and blood clot disorders.
🔄 Alternative Options
Generic Alternatives
- Progesterone injection
Brand Alternatives
- Susten 100 injection