udzire 100mg tablet - Udenafil (100mg) medicine

Udzire 100mg Tablet: Comprehensive Guide to Uses, Side Effects, and Safety

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🏭 Zydus Cadila 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for erectile dysfunction.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Erection lasting more than 4 hours
  • Sudden vision loss
  • Sudden hearing loss
  • Chest pain or difficulty breathing
  • Severe dizziness or fainting
  • Signs of allergic reaction (rash, swelling, difficulty breathing)

If experiencing severe symptoms, call emergency services immediately.

What is udzire 100mg tablet used for?

This medicine contains Udenafil 100 mg, a PDE5 inhibitor used to treat erectile dysfunction in adult men. It works by increasing blood flow to the penis during sexual stimulation. It is taken orally about 30-60 minutes before sexual activity and should not be used with nitrates.

  • Generic Name: Udenafil (100mg)
  • Manufacturer: Zydus Cadila
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 udzire 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उडेनाफिल 100 मिलीग्राम युक्त है और इसका उपयोग वयस्क पुरुषों में स्तंभन दोष (इरेक्टाइल डिसफंक्शन) के इलाज के लिए किया जाता है। यह दवा पीडीई5 इनहिबिटर वर्ग की है और यौन उत्तेजना के दौरान लिंग में रक्त के प्रवाह को बढ़ाकर काम करती है। यह दवा यौन उत्तेजना के बिना स्तंभन नहीं करती। इसका सेवन डॉक्टर के परामर्श के अनुसार ही करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, चेहरे पर लालिमा, अपच, नाक बंद होना और चक्कर आना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में लंबे समय तक स्तंभन (प्रियापिज्म), अचानक दृष्टि हानि, अचानक सुनने की हानि और गंभीर एलर्जी प्रतिक्रियाएं शामिल हैं। इनके होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। 24 घंटे में एक से अधिक खुराक न लें। शराब से बचें क्योंकि इससे रक्तचाप कम हो सकता है और दवा का असर कम हो सकता है। नाइट्रेट या नाइट्रिक ऑक्साइड डोनर के साथ इस दवा का सेवन न करें। यदि स्तंभन 4 घंटे से अधिक समय तक बना रहे तो तुरंत आपातकालीन चिकित्सा सहायता लें।

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 udzire 100mg tablet Uses & Benefits

[{"condition":"Erectile Dysfunction","description":"This medicine is used to treat erectile dysfunction in adult men by improving blood flow to the penis during sexual stimulation.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Erectile Dysfunction

📋 Drug Information

Generic Name(s)Udenafil (100mg)
Brand Nameudzire 100mg tablet
ManufacturerZydus Cadila
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassSEX STIMULANTS REJUVENATORS
Action ClassPhosphodiesterase-V inhibitors
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine approximately 30 to 60 minutes before sexual activity.
2
Do not take more than one dose in 24 hours.
3
Avoid alcohol while taking this medicine as it may increase side effects.
4
Inform your doctor if you have heart, liver, or kidney problems.
5
Do not take this medicine with nitrates or nitric oxide donors.
6
Seek immediate medical help if you experience a prolonged erection lasting more than 4 hours.
7
This medicine does not protect against sexually transmitted infections; use appropriate protection.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Erectile dysfunction
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionUdenafil is rapidly absorbed after oral administration. The absolute bioavailability is not established from the available information.
DistributionThe volume of distribution of udenafil is not established from the available information.
Protein BindingUdenafil is highly bound to plasma proteins (approximately 93-95%).
MetabolismUdenafil is primarily metabolized in the liver by cytochrome P450 3A4 (CYP3A4) enzymes.
Half-LifeThe elimination half-life of udenafil is approximately 11-13 hours.
ExcretionUdenafil is excreted mainly in the feces as metabolites, with a small amount excreted in urine.
BioavailabilityThe absolute bioavailability of udenafil is not established from the available information.
Onset of ActionThe onset of action is typically within 30 to 60 minutes after oral administration.
Peak Plasma TimePeak plasma concentrations are reached approximately 1 to 1.5 hours after oral administration.
Duration of ActionThe duration of action is approximately 12 to 24 hours, allowing for a longer window of opportunity compared to some other PDE5 inhibitors.

How It Works

Udenafil is a selective inhibitor of phosphodiesterase type 5 (PDE5). By inhibiting PDE5, it prevents the breakdown of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the corpus cavernosum. This leads to relaxation of smooth muscle and increased blood flow to the penis, facilitating erection when sexual stimulation occurs.

Mechanism Steps

1
Inhibition of PDE5: Udenafil selectively binds to and inhibits the PDE5 enzyme in the corpus cavernosum.
2
Increased cGMP: Inhibition of PDE5 prevents the breakdown of cGMP, leading to higher levels of cGMP in the smooth muscle cells.
3
Smooth muscle relaxation: Elevated cGMP causes relaxation of the smooth muscle in the penile arteries and corpus cavernosum.
4
Increased blood flow: Relaxation of smooth muscle increases blood flow into the penis, resulting in an erection when sexually stimulated.

💡 How to Take udzire 100mg tablet

Strength: 100 mg immediate-release tablet

1Take this medicine orally with a glass of water.
2Take it approximately 30 to 60 minutes before sexual activity.
3Do not take more than one dose in 24 hours.
4Avoid taking with a high-fat meal as it may delay the onset of action.
5Do not take with nitrates or nitric oxide donors.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100 mg taken orally approximately 30 to 60 minutes before sexual activity. The dose may be adjusted by a qualified clinician based on individual response and tolerability. Do not take more than one dose in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be required. Consult a doctor.
Renal ImpairmentUse with caution in patients with severe renal impairment. Dose adjustment may be required. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be required. Consult a doctor.
Maximum Daily Dose100 mg per day.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

High-fat meal
Avoid taking with high-fat meal
May delay absorption and onset of action.
Grapefruit
Avoid
May increase drug levels by inhibiting CYP3A4.

⏰ What to Do If You Miss a Dose

📌 This medicine is taken on demand
→ A missed dose is not applicable.
💡 Do not take more than one dose in 24 hours.

⚠️ Side Effects of udzire 100mg tablet

✅ Common Side Effects

Headache (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent or severe.
Flushing (Common (5-10%))
Usually resolves on its own. Consult doctor if bothersome.
Indigestion (Common (5-10%))
Take with food to reduce stomach upset. Consult doctor if persistent.
Nasal congestion (Common (5-10%))
Usually resolves on its own. Consult doctor if persistent.
Dizziness (Common (5-10%))
Avoid driving or operating machinery if affected. Consult doctor if persistent.

🚨 Serious Side Effects

Priapism (prolonged erection) (Rare (<0.1%))
Seek immediate medical attention if erection lasts more than 4 hours.
Sudden vision loss (Rare (<0.1%))
Seek immediate medical attention.
Sudden hearing loss (Rare (<0.1%))
Seek immediate medical attention.
Severe allergic reaction (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Seizures
Transient global amnesia
Increased intraocular pressure

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Nitrates Major
Alpha-blockers Major
CYP3A4 inhibitors Major
CYP3A4 inducers Moderate
Grapefruit juice Moderate

🚨 Major Interactions

  • Nitrates (e.g., nitroglycerin, isosorbide mononitrate)
  • Alpha-blockers (e.g., doxazosin, terazosin)
  • CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)

⚡ Moderate Interactions

  • CYP3A4 inducers (e.g., rifampin, carbamazepine)
  • Grapefruit juice

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, headache, and low blood pressure. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Concomitant use of nitrates or nitric oxide donors","Severe cardiovascular disease (e.g., recent stroke or myocardial infarction)","Severe hepatic impairment","Severe hypotension","Known hypersensitivity to udenafil"]

⚠️ Warnings & Precautions

["This medicine should not be used in women or children.","This medicine does not protect against sexually transmitted infections.","Use with caution in patients with anatomical deformation of the penis.","Use with caution in patients with conditions predisposing to priapism.","Use with caution in patients with bleeding disorders or active peptic ulcer.","Use with caution in patients with retinitis pigmentosa."]

🤱 Lactation Safety

Not applicable. This medicine is not indicated for use in women.

💊 Overdose Management

Overdose may cause severe hypotension, priapism, and other side effects. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

This medicine is taken on demand, so a missed dose is not applicable. Do not take more than one dose in 24 hours.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not take more than one dose in 24 hours. Avoid alcohol, as it can increase the risk of low blood pressure and reduce the effectiveness of this medicine. Do not take this medicine with nitrates or nitric oxide donors. Inform your doctor about all other medicines you are taking, especially alpha-blockers, antifungals, and antibiotics. If you experience a prolonged erection lasting more than 4 hours, seek emergency medical attention immediately. This medicine does not protect against sexually transmitted infections; use appropriate protection.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be required. Consult a doctor.

🤰 Pregnancy Planning (TTC)

Not applicable. This medicine is not indicated for use in women.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, especially if you have undergone prostate surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, especially before any surgical dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the risk of erectile dysfunction.
🥗
Regular exercise improves cardiovascular health and blood flow.
😴
Avoid smoking as it can worsen erectile dysfunction.
💧
Limit alcohol consumption.
🧘
Manage stress through relaxation techniques.
🌞
Get adequate sleep.

🏋️ Exercise Considerations

Regular exercise is beneficial, but avoid strenuous activity if you have cardiovascular disease. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include fruits and vegetables rich in antioxidants.
Reduce intake of processed and high-fat foods.
Stay well hydrated.
Limit alcohol and caffeine.

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some individuals. Avoid driving or operating heavy machinery if you experience dizziness. It does not affect your ability to work otherwise.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects, seek immediate medical attention.

📅 Long-Term Use Effects

Long-term use of this medicine has not been associated with significant adverse effects in clinical studies. However, regular monitoring of blood pressure and cardiovascular health is recommended. Consult your doctor for periodic evaluation.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Weight loss, exercise, and stress reduction can improve erectile function.

Evidence: Well-established
Psychotherapy

Can be helpful for psychogenic erectile dysfunction.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccination considerations are associated with this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, take the medicine as needed for sexual activity, but do not exceed one dose in 24 hours. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with erectile dysfunction
He was prescribed this medicine by his doctor. He took it 45 minutes before sexual activity and noticed improvement in his ability to achieve and maintain an erection. He experienced mild headache which resolved on its own. He was advised to avoid alcohol and nitrates.
💡 Lesson: Taking this medicine as prescribed and avoiding alcohol and nitrates can improve efficacy and safety.
👤 A 62-year-old man with a history of hypertension
He was started on this medicine after a thorough cardiac evaluation. He was advised to monitor his blood pressure and avoid alpha-blockers. He responded well to the treatment without any serious side effects.
💡 Lesson: Cardiac evaluation and monitoring are important before starting this medicine in patients with cardiovascular risk factors.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts working within 30 to 60 minutes after oral administration.

Q: How long does the effect last?

A: The effect can last up to 12 to 24 hours, allowing a longer window of opportunity.

Q: Can I take it daily?

A: This medicine is usually taken on demand, not daily. Consult your doctor for daily use.

Q: Is it safe with alcohol?

A: Alcohol may increase the risk of side effects such as dizziness and low blood pressure. It is advisable to avoid or limit alcohol.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: Udenafil is an aphrodisiac.
    Fact: Udenafil is not an aphrodisiac; it requires sexual stimulation to work.
  • Myth: Udenafil can be taken with nitrates.
    Fact: Udenafil is contraindicated with nitrates due to severe hypotension risk.

📊 Comparison with Similar Medicines

[{"medicine":"Udenafil","onset":"30-60 minutes","duration":"12-24 hours","half_life":"11-13 hours"},{"medicine":"Sildenafil","onset":"30-60 minutes","duration":"4-6 hours","half_life":"3-5 hours"},{"medicine":"Tadalafil","onset":"30-120 minutes","duration":"24-36 hours","half_life":"17.5 hours"}]

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