Ubiphene 100 Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain or bloating
- Rapid weight gain over a few days
- Difficulty breathing or shortness of breath
- Blurred vision or double vision
- Yellowing of skin or eyes
- Dark urine or severe fatigue
- Sudden swelling in one leg or chest pain
- Severe headache with visual changes
If experiencing severe symptoms, call emergency services immediately.
What is ubiphene 100 tablet used for?
This medicine is a combination of Clomiphene 100 mg and Coenzyme Q10 100 mg used to induce ovulation in women with anovulatory infertility. It works by stimulating the release of hormones that trigger egg release from the ovaries. Coenzyme Q10 supports egg quality. It should only be taken under medical supervision.
- Generic Name: Clomiphene (100mg) + Coenzyme Q10 (100mg)
- Manufacturer: Fourrts India Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ubiphene 100 tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्लोमीफीन 100 मिलीग्राम और कोएंजाइम Q10 100 मिलीग्राम का संयोजन है, जिसका उपयोग महिलाओं में ओव्यूलेशन (अंडोत्सर्जन) को प्रेरित करने के लिए किया जाता है। यह उन महिलाओं के लिए है जो नियमित रूप से ओव्यूलेट नहीं करती हैं और गर्भधारण करने में कठिनाई का सामना कर रही हैं। क्लोमीफीन मस्तिष्क में एस्ट्रोजन रिसेप्टर्स को अवरुद्ध करता है, जिससे पिट्यूटरी ग्रंथि से FSH और LH हार्मोन अधिक मात्रा में निकलते हैं और अंडाशय अंडे का उत्पादन और रिलीज करता है। कोएंजाइम Q10 एक एंटीऑक्सिडेंट है जो अंडे की गुणवत्ता में सुधार करने में मदद कर सकता है। यह दवा केवल एक योग्य डॉक्टर की देखरेख में ही लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में गर्म लहरें (हॉट फ्लैश), मूड स्विंग, स्तन में कोमलता, मतली, पेट फूलना और सिरदर्द शामिल हैं। कुछ महिलाओं को धुंधली दृष्टि या दोहरी दृष्टि जैसी दृश्य गड़बड़ी हो सकती है, जिसकी तुरंत डॉक्टर को सूचना देनी चाहिए। ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम (OHSS) एक दुर्लभ लेकिन गंभीर दुष्प्रभाव है जिसमें पेट में दर्द, सूजन, तेजी से वजन बढ़ना और सांस लेने में कठिनाई शामिल है। अन्य गंभीर दुष्प्रभावों में लीवर विषाक्तता, रक्त के थक्के और अंडाशय में पुटिकाएं शामिल हैं।
सुरक्षा सलाह: यह दवा केवल एक योग्य प्रजनन विशेषज्ञ या स्त्री रोग विशेषज्ञ की देखरेख में ही लेनी चाहिए। बिना डॉक्टर की सलाह के खुराक न बदलें। उपचार शुरू करने से पहले अपने डॉक्टर को लीवर रोग, गुर्दे की समस्या, रक्त के थक्के विकार या अंडाशय की पुटिकाओं के इतिहास के बारे में बताएं। ओव्यूलेशन की निगरानी के लिए नियमित अल्ट्रासाउंड और हार्मोन परीक्षण आवश्यक हैं। गर्भवती होने पर यह दवा न लें। यदि आप गर्भवती हो जाती हैं, तो दवा बंद करें और तुरंत डॉक्टर से मिलें।
💊 ubiphene 100 tablet Uses & Benefits
[{"condition":"Ovulation induction in anovulatory infertility","description":"This medicine is used to stimulate ovulation in women who do not ovulate regularly, including those with polycystic ovary syndrome (PCOS).","evidence":"Well-established"},{"condition":"Unexplained infertility","description":"Sometimes used to increase the number of eggs released per cycle, improving chances of conception in couples with unexplained infertility.","evidence":"Moderate"},{"condition":"Luteal phase defect","description":"May be used to improve ovulation and support the luteal phase in women with short or inadequate luteal phases.","evidence":"Limited"}]
Off-label uses: [{"condition":"Male infertility","description":"Clomiphene is sometimes prescribed off-label to men with low testosterone or poor sperm quality to improve sperm production.","evidence":"Limited"},{"condition":"Gynecomastia","description":"Rarely used off-label in men to treat breast enlargement by altering estrogen levels.","evidence":"Limited"}]
Primary treatment for: Anovulatory infertility
Also treats: Polycystic ovary syndrome (PCOS), Unexplained infertility, Luteal phase defect
📋 Drug Information
| Generic Name(s) | Clomiphene (100mg) + Coenzyme Q10 (100mg) |
| Brand Name | ubiphene 100 tablet |
| Manufacturer | Fourrts India Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GYNAECOLOGICAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. Do not refrigerate unless specified. Keep out of reach of children and pets. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Clomiphene is a selective estrogen receptor modulator (SERM) that binds to estrogen receptors in the hypothalamus and pituitary gland, blocking the negative feedback effect of estrogen. This leads to increased secretion of gonadotropin-releasing hormone (GnRH), which in turn stimulates the pituitary to release more follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Elevated FSH and LH levels stimulate the ovaries to develop and release eggs. Coenzyme Q10 is a fat-soluble antioxidant that plays a critical role in mitochondrial energy production and protects cells from oxidative damage. In the context of fertility, Coenzyme Q10 may improve egg quality by reducing oxidative stress in ovarian follicles and enhancing mitochondrial function in oocytes.
Mechanism Steps
💡 How to Take ubiphene 100 tablet
Strength: Each tablet contains Clomiphene 100 mg and Coenzyme Q10 100 mg. Immediate-release oral tablet.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally once daily or as directed by your fertility specialist. The dose and duration of treatment depend on your individual response, medical history, and the specific fertility issue being treated. Typically, treatment is started on day 2, 3, 4, or 5 of the menstrual cycle and continued for 5 days. Ovulation usually occurs 5 to 10 days after completing the course. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This medicine is not intended for use in children. Consult a pediatrician for any concerns. |
| Elderly Dosage | This medicine is not intended for use in elderly patients. Fertility treatment is typically not indicated in this population. Consult a doctor for appropriate guidance. |
| Renal Impairment | No specific dose adjustment is established for patients with renal impairment. Use with caution and under medical supervision. Monitor renal function if pre-existing kidney disease is present. |
| Hepatic Impairment | This medicine is contraindicated in patients with liver disease. No specific dose adjustment is established. Use with caution and under medical supervision if mild hepatic impairment is present. Monitor liver function tests regularly. |
| Maximum Daily Dose | The maximum recommended daily dose is 100 mg of clomiphene and 100 mg of Coenzyme Q10, or as prescribed by your doctor. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ubiphene 100 tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Tamoxifen | Major | |
| Fluoxetine | Moderate | |
| Paroxetine | Moderate | |
| Rifampin | Moderate | |
| Carbamazepine | Moderate | |
| Antacids | Minor | |
| Warfarin (with Coenzyme Q10) | Minor |
🚨 Major Interactions
- Warfarin
- Tamoxifen
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
- CYP2D6 inducers (e.g., rifampin, carbamazepine)
🍷 Alcohol Interaction
Alcohol may worsen side effects such as dizziness, mood swings, and nausea. It can also reduce fertility and interfere with treatment outcomes. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Pregnancy or suspected pregnancy","Liver disease or history of liver dysfunction","Unexplained abnormal vaginal bleeding","Ovarian cysts not due to polycystic ovary syndrome","Hypersensitivity to clomiphene or Coenzyme Q10","History of blood clots or thrombophlebitis"]
⚠️ Warnings & Precautions
["This medicine should only be used under the supervision of a fertility specialist.","Regular monitoring with ultrasound is required to assess ovarian response and prevent multiple pregnancies.","Visual disturbances may occur; stop the medicine and consult a doctor immediately if they occur.","Ovarian hyperstimulation syndrome (OHSS) is a rare but serious risk; report symptoms immediately.","Avoid alcohol and smoking as they can reduce fertility and increase side effects.","Do not take this medicine if you are already pregnant.","Use with caution in patients with a history of liver or kidney disease.","Coenzyme Q10 may interact with warfarin; monitor INR closely."]
🤱 Lactation Safety
It is not known whether clomiphene or Coenzyme Q10 are excreted in human breast milk. Because of the potential for serious adverse reactions in nursing infants, this medicine is not recommended during breastfeeding. Consult your doctor for alternative options.
💊 Overdose Management
Overdose of this medicine may cause severe ovarian hyperstimulation, visual disturbances, nausea, vomiting, and abdominal pain. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if ingestion is recent. Monitor vital signs, electrolytes, and ovarian size.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. Consult your doctor if you are unsure.
Additional Safety Advice
This medicine should only be taken under the supervision of a qualified fertility specialist or gynecologist. Do not self-medicate or adjust the dose without medical advice. Before starting treatment, inform your doctor about any liver disease, kidney problems, blood clotting disorders, or history of ovarian cysts. Regular monitoring with ultrasound and hormone tests is essential to assess ovarian response and reduce the risk of multiple pregnancies or ovarian hyperstimulation syndrome. Avoid alcohol and smoking while taking this medicine, as they can reduce fertility and increase side effects. If you experience severe abdominal pain, rapid weight gain, or difficulty breathing, seek immediate medical attention. Do not take this medicine if you are already pregnant. If you become pregnant during treatment, stop the medicine and consult your doctor immediately. Store this medicine in a cool, dry place away from direct sunlight and out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
This medicine is not intended for use in elderly patients. Fertility treatment is typically not indicated in this population. Consult a doctor for appropriate guidance.
🤰 Pregnancy Planning (TTC)
This medicine is used to induce ovulation in women trying to conceive. It should be taken exactly as prescribed by your fertility specialist. If you become pregnant during treatment, stop the medicine immediately and consult your doctor. Regular monitoring is essential to ensure safe ovulation and minimize risks.
🏥 Post-Surgery Considerations
If you are planning to undergo surgery, inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be stopped before surgery due to the risk of blood clots. Consult your doctor for specific instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. There are no specific contraindications, but it is important for your dentist to be aware of all medicines you are taking.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness or visual disturbances, avoid activities that require mental alertness, such as driving or operating heavy machinery. Consult your doctor before starting any new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, mood swings, or visual disturbances in some women, which could affect your ability to drive or operate machinery. It is advisable to avoid driving or operating heavy machinery until you know how this medicine affects you. Most women can continue their normal daily activities with minimal disruption.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor immediately if you experience visual disturbances, severe abdominal pain, rapid weight gain, difficulty breathing, or signs of an allergic reaction. If you become pregnant, stop the medicine and inform your doctor. Do not stop taking this medicine without consulting your doctor for any other reason.
📅 Long-Term Use Effects
Long-term use of this medicine beyond the recommended duration is not advised without medical supervision. Prolonged use may increase the risk of ovarian cysts, liver toxicity, and visual disturbances. Regular monitoring of liver function, ovarian response, and visual acuity is recommended. The optimal duration of treatment is typically limited to a few cycles, and alternative treatments should be considered if pregnancy does not occur.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
An aromatase inhibitor that is often used as a first-line treatment for ovulation induction, especially in women with PCOS.
Evidence: Well-establishedAn insulin-sensitizing agent that can improve ovulation in women with PCOS, often used in combination with clomiphene.
Evidence: ModerateInjectable hormones that directly stimulate the ovaries, used when oral agents fail.
Evidence: Well-establishedWeight loss, diet, and exercise can improve ovulation and fertility in overweight women.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, it is always advisable to inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking the medicine at the same time each day as prescribed. Keep it in your carry-on luggage to avoid loss. Check customs regulations for carrying prescription medicines to your destination.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Ovulation typically occurs 5 to 10 days after completing a 5-day course of this medicine. However, it may take several cycles to achieve pregnancy.
A: No, this medicine is a prescription drug and should only be taken under the supervision of a fertility specialist.
A: The risk of multiple pregnancies, including twins, is increased with this medicine but is not guaranteed. Most pregnancies are singleton.
A: Yes, this medicine is commonly prescribed for ovulation induction in women with PCOS. However, it must be monitored closely.
A: Stop taking this medicine immediately and consult your doctor. Visual disturbances are a serious side effect.
🤔 Common Patient Concerns
🔄 Substitutes for ubiphene 100 tablet
View AllAlternative brands with exact same active ingredient:
-
clomipreg q 100mg/100mg tabletRemedial Healthcare ₹396.70 3.8% COSTLIER
-
Ferticleft C 100mg/100mg CapsuleIndiabulls pharmaceutical ltd ₹449.00 17.5% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine guarantees pregnancy.
Fact: This medicine induces ovulation but does not guarantee pregnancy. Many factors contribute to conception. - Myth: This medicine always causes twins.
Fact: The risk of multiple pregnancies is increased but not guaranteed. Most pregnancies are singleton. - Myth: This medicine can be taken without monitoring.
Fact: Regular monitoring with ultrasound and hormone tests is essential for safety and efficacy. - Myth: Coenzyme Q10 in this medicine is unnecessary.
Fact: Coenzyme Q10 may improve egg quality and ovarian response, complementing clomiphene's effects.
🔄 Alternative Options
Generic Alternatives
- Clomiphene 100 mg + Coenzyme Q10 100 mg tablet (various manufacturers)
Brand Alternatives
- Ubiphene 100 Tablet