Tolperitas-D Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Unusual bleeding or bruising
If experiencing severe symptoms, call emergency services immediately.
What is Tolaus D 150mg/50mg Tablet used for?
This medicine is a combination of tolperisone (a muscle relaxant) and diclofenac (an NSAID) used for short-term relief of painful muscle spasms and inflammation in conditions like back pain and sports injuries. It is taken orally with food, usually 1 tablet up to three times daily, and should not be used long-term without medical supervision.
- Generic Name: Tolperisone (150mg) + Diclofenac (50mg)
- Manufacturer: Care Formulation Labs Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Tolaus D 150mg/50mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा टॉलपेरिसोन और डाइक्लोफेनाक का संयोजन है, जिसका उपयोग मांसपेशियों में ऐंठन और दर्द के इलाज के लिए किया जाता है। यह पीठ दर्द, गर्दन में दर्द, चोट या सर्जरी के बाद होने वाले दर्द और सूजन में राहत देती है। यह दवा मांसपेशियों को आराम देती है और सूजन कम करती है। इसे डॉक्टर की सलाह के अनुसार ही लें और लंबे समय तक न लें।
साइड इफेक्ट्स: आम दुष्प्रभावों में जी मिचलाना, पेट दर्द, सिरदर्द, चक्कर आना और मुंह सूखना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, गुर्दे की समस्या, यकृत की समस्या और एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, तेज पेट दर्द, सांस लेने में कठिनाई या चेहरे पर सूजन हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन या दूध के साथ लें ताकि पेट में जलन न हो। शराब न पिएं क्योंकि इससे पेट में रक्तस्राव का खतरा बढ़ सकता है। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। अन्य दर्द निवारक दवाओं के साथ इसका सेवन न करें।
💊 Tolaus D 150mg/50mg Tablet Uses & Benefits
[{"condition":"Acute musculoskeletal pain with muscle spasm","description":"Relieves pain and reduces muscle spasm in conditions such as neck pain, back pain, and sports injuries.","evidence":"Well-established"},{"condition":"Low back pain","description":"Provides short-term relief of pain and improves mobility in acute low back pain associated with muscle spasm.","evidence":"Well-established"},{"condition":"Post-operative pain and spasm","description":"Used after surgery to reduce pain and muscle spasm, often as part of multimodal analgesia.","evidence":"Moderate"},{"condition":"Post-traumatic pain","description":"Helps manage pain and inflammation" class="semantic-link" title="Medicines for swelling">swelling after injuries such as sprains and strains.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Tension-type headache","description":"Sometimes prescribed off-label for tension headaches with muscle tightness, but evidence is limited.","evidence":"Limited"},{"condition":"Fibromyalgia","description":"Occasionally used off-label for fibromyalgia pain, but not recommended as first-line therapy.","evidence":"Limited"}]
Primary treatment for: Musculoskeletal pain with muscle spasm
Also treats: Low back pain, Neck pain, Post-operative pain, Post-traumatic pain
📋 Drug Information
| Generic Name(s) | Tolperisone (150mg) + Diclofenac (50mg) |
| Brand Name | Tolaus D 150mg/50mg Tablet |
| Manufacturer | Care Formulation Labs Pvt Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with different mechanisms. Tolperisone is a centrally acting muscle relaxant that blocks voltage-gated sodium channels and reduces excitatory neurotransmitter release in the spinal cord and brainstem, leading to decreased muscle tone and spasm. Diclofenac is a nonsteroidal anti-inflammatory drug that reversibly inhibits cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes, thereby reducing the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. The combination provides both muscle relaxation and anti-inflammatory pain relief.
Mechanism Steps
💡 How to Take Tolaus D 150mg/50mg Tablet
Strength: Tablet containing tolperisone 150 mg and diclofenac 50 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally one to three times daily, depending on the severity of pain and muscle spasm. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. Take with food or milk to reduce stomach upset. Use for the shortest duration necessary. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of this medicine. Use the lowest effective dose and monitor closely for side effects, especially gastrointestinal bleeding and kidney problems. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Use with caution in patients with kidney disease. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with liver disease. Dose adjustment may be necessary. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet three times daily (tolperisone 450 mg and diclofenac 150 mg). Do not exceed this dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Tolaus D 150mg/50mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Ibuprofen | Major | |
| Corticosteroids | Major | |
| Methotrexate | Major | |
| Lithium | Major | |
| ACE inhibitors | Moderate | |
| Diuretics | Moderate | |
| SSRIs | Moderate | |
| Fluconazole | Moderate | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Other NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
- Methotrexate
- Lithium
⚡ Moderate Interactions
- ACE inhibitors and ARBs
- Diuretics
- SSRIs
- CYP2C9 inhibitors (e.g., fluconazole)
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of gastrointestinal bleeding and may worsen liver toxicity. It can also increase drowsiness and dizziness.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Active peptic ulcer or gastrointestinal bleeding","Severe kidney disease","Severe liver disease","Heart failure (NYHA class III-IV)","History of asthma, urticaria, or allergic reaction to NSAIDs","Third trimester of pregnancy","Known allergy to tolperisone or diclofenac","Coronary artery bypass graft surgery (peri-operative period)"]
⚠️ Warnings & Precautions
["Use with caution in elderly patients due to increased risk of side effects.","Avoid in patients with dehydration or hypovolemia.","Use with caution in patients with hypertension or cardiovascular disease.","May impair ability to drive or operate machinery.","Do not use with other NSAIDs.","Monitor for signs of gastrointestinal bleeding.","Use with caution in patients with asthma.","Avoid alcohol consumption."]
🤱 Lactation Safety
Not established from the available information. Diclofenac is excreted in breast milk in small amounts. Tolperisone may also pass into breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, dizziness, drowsiness, and in severe cases, gastrointestinal bleeding, kidney failure, or liver damage. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Activated charcoal may be considered if overdose is recent. Monitor vital signs, kidney and liver function, and manage complications.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Take it with food or milk to reduce stomach irritation. Avoid alcohol because it can increase the risk of stomach bleeding and liver problems. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of ulcers, kidney or liver disease, heart problems, or asthma. Do not use this medicine with other NSAIDs or blood thinners unless your doctor approves. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function regularly.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy, especially in the third trimester. If you are planning pregnancy, consult your doctor to discuss alternative treatments.
🏥 Post-Surgery Considerations
This medicine may be used for post-operative pain and muscle spasm. However, it should be used with caution after surgery due to the risk of bleeding and kidney problems. Follow your surgeon's instructions.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure, as it may increase the risk of bleeding. Your dentist may advise you to stop it temporarily.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you feel dizzy or drowsy. Gentle stretching and low-impact activities may be beneficial. Consult your doctor before starting any exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause stomach upset, so take it with food.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if you experience severe side effects such as stomach bleeding, kidney problems, or allergic reactions. Do not stop abruptly without consulting your doctor if you have been taking it for a long time.
📅 Long-Term Use Effects
Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney problems, liver toxicity, and cardiovascular events. It is not recommended for extended use without medical supervision. Regular monitoring of kidney and liver function may be required.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain.
Evidence: Well-establishedMay help relieve muscle spasm and pain.
Evidence: ModerateMay provide pain relief for some patients.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Declare it at customs if required. Keep it in your carry-on luggage.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Pain relief may begin within 30 to 60 minutes, while muscle relaxant effects may take a few hours.
A: It is best taken with food or milk to reduce stomach irritation.
A: No, taking with other NSAIDs can increase the risk of side effects. Consult your doctor.
🤔 Common Patient Concerns
🔄 Substitutes for Tolaus D 150mg/50mg Tablet
View AllAlternative brands with exact same active ingredient:
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cvcon-d tabletCorpus Callosum ₹117.19 19% COSTLIER
-
Tolbia D 150mg/50mg TabletAlbia Biocare ₹121.88 23.8% COSTLIER
-
mydoz d 150mg/50mg tabletFawn Incorporation ₹126.47 28.5% COSTLIER
-
tolexant d 150mg/50mg tabletLeeford Healthcare Ltd ₹126.50 28.5% COSTLIER
-
tolsia-d tabletCurasia Medilabs ₹126.56 28.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken long-term for chronic pain.
Fact: This medicine is intended for short-term use only. Long-term use increases the risk of serious side effects. - Myth: It is safe to take with other painkillers.
Fact: Taking with other NSAIDs can increase the risk of bleeding and kidney problems. Always consult your doctor. - Myth: It can be taken on an empty stomach.
Fact: It should be taken with food or milk to reduce stomach irritation.
🔄 Alternative Options
Generic Alternatives
- Tolperisone + Diclofenac combination tablets from other manufacturers
Brand Alternatives
- Tolperitas-D Tablet