tinimox tablet - Amoxycillin (500mg) + Tinidazole (300mg) medicine

Moxikind TZ Tablet: Complete Medicine Guide

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🏭 Dr Reddy's Laboratories Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 24, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Amoxycillin is generally considered safe in pregnancy (FDA category B). Tinidazole is not recommended in the first trimester; use in second and third trimester only if clearly needed (FDA category C). Consult your doctor for risk-benefit assessment. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 24, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bruising or bleeding
  • Numbness or tingling in hands or feet
  • Seizures

If experiencing severe symptoms, call emergency services immediately.

What is tinimox tablet used for?

This medicine is a combination antibiotic containing amoxycillin and tinidazole, used to treat mixed bacterial and protozoal infections such as amoebic liver abscess, giardiasis, trichomoniasis, and dental abscesses. It works by killing bacteria and protozoa. It is available only by prescription and must be taken exactly as directed.

  • Generic Name: Amoxycillin (500mg) + Tinidazole (300mg)
  • Manufacturer: Dr Reddy's Laboratories Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 tinimox tablet के बारे में (Hindi Summary)

उपयोग: यह दवा अमोक्सिसिलिन और टिनिडाजोल का संयोजन है, जिसका उपयोग विभिन्न जीवाणु और प्रोटोज़ोआ संक्रमणों के इलाज के लिए किया जाता है। यह अमीबिक लिवर एब्सेस, जियार्डिया, ट्राइकोमोनिएसिस, बैक्टीरियल वेजिनोसिस, दांतों के फोड़े और पेट के संक्रमण में प्रभावी है। यह दवा केवल डॉक्टर के पर्चे पर मिलती है और पूरा कोर्स करना जरूरी है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, धातु जैसा स्वाद, दस्त, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, रक्त विकार, यकृत समस्याएं और शराब के साथ प्रतिक्रिया शामिल हैं। यदि आपको सांस लेने में कठिनाई, चेहरे पर सूजन, या गंभीर दस्त हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। कोर्स पूरा करें, बीच में न छोड़ें। शराब का सेवन बिल्कुल न करें, क्योंकि इससे गंभीर प्रतिक्रिया हो सकती है। दवा को भोजन के साथ लें। यदि आपको गुर्दे या यकृत की समस्या है तो डॉक्टर को बताएं। दवा को ठंडी और सूखी जगह पर रखें। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 tinimox tablet Uses & Benefits

  • [{"condition":"Amoebic liver abscess","description":"This medicine is used to treat liver abscess caused by Entamoeba histolytica, combining tissue amoebicidal action of tinidazole with broad-spectrum antibacterial coverage of amoxycillin.","evidence":"Well-established"},{"condition":"Giardiasis","description":"Effective against Giardia lamblia infection, which causes diarrhea and malabsorption.
  • Tinidazole provides targeted antiprotozoal activity.","evidence":"Well-established"},{"condition":"Trichomoniasis","description":"Used to treat Trichomonas vaginalis infection in women and men.
  • Tinidazole is highly effective against this protozoan.","evidence":"Well-established"},{"condition":"Bacterial vaginosis","description":"This combination helps treat mixed anaerobic bacterial vaginosis, with tinidazole covering anaerobes and amoxycillin providing additional bacterial coverage.","evidence":"Moderate"},{"condition":"Dental abscess","description":"Prescribed for dental infections involving anaerobic bacteria, often as an adjunct to dental procedures.","evidence":"Moderate"},{"condition":"Intra-abdominal infections","description":"Used in mixed aerobic-anaerobic intra-abdominal infections, such as peritonitis or abscesses, often after surgical drainage.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes included in combination regimens for H. pylori, though not a standard first-line choice.","evidence":"Limited"},{"condition":"Rosacea","description":"Rarely used off-label for rosacea due to its anti-inflammatory and antiprotozoal effects, but evidence is limited.","evidence":"Limited"}]

Primary treatment for: Mixed bacterial and protozoal infections

Also treats: Amoebic liver abscess, Giardiasis, Trichomoniasis, Bacterial vaginosis, Dental abscess, Intra-abdominal infections

📋 Drug Information

Generic Name(s)Amoxycillin (500mg) + Tinidazole (300mg)
Brand Nametinimox tablet
ManufacturerDr Reddy's Laboratories Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always prescribe this medicine with food to reduce gastrointestinal upset.
2
Instruct patients to avoid alcohol completely during and for 72 hours after treatment.
3
Consider dose adjustment in patients with renal or hepatic impairment.
4
Monitor for signs of allergic reactions, especially in patients with penicillin allergy.
5
Complete the full course to prevent resistance and recurrence.
6
Warn patients about the metallic taste and temporary nature of this side effect.
7
Use with caution in patients with CNS disorders due to risk of seizures.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

❌
Chronic joint pain
This medicine is not a pain reliever for joint pain.
Not Primary
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Diarrhea with greasy stools
May be prescribed for giardiasis.
Likely Use
✅
Vaginal discharge with odor
May be prescribed for bacterial vaginosis or trichomoniasis.
Likely Use
✅
Tooth pain with swelling
May be prescribed for dental abscess.
Likely Use

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAmoxycillin is well absorbed from the gastrointestinal tract after oral administration, with a bioavailability of approximately 80-90%. Tinidazole is also rapidly and completely absorbed orally, with a bioavailability approaching 100%.
DistributionAmoxycillin distributes widely into body tissues and fluids, including liver, lungs, and urine. Tinidazole distributes extensively into tissues and crosses the blood-brain barrier and placenta.
Protein BindingAmoxycillin is about 17-20% protein-bound. Tinidazole is approximately 12% protein-bound.
MetabolismAmoxycillin undergoes limited metabolism, primarily to penicilloic acid. Tinidazole is metabolized in the liver, mainly by oxidation and glucuronidation.
Half-LifeThe elimination half-life of amoxycillin is approximately 1 to 1.5 hours. Tinidazole has a longer half-life of about 12 to 14 hours.
ExcretionAmoxycillin is excreted primarily unchanged in the urine. Tinidazole is excreted in urine and feces, with about 20-25% unchanged in urine.
BioavailabilityAmoxycillin oral bioavailability is about 80-90%. Tinidazole oral bioavailability is approximately 100%.
Onset of ActionOnset of action for amoxycillin is within 1-2 hours; tinidazole begins to act within 1-2 hours as well.
Peak Plasma TimePeak plasma concentrations for amoxycillin occur at 1-2 hours; for tinidazole, peak levels are reached at 2 hours.
Duration of ActionAmoxycillin's antibacterial effect lasts about 6-8 hours per dose. Tinidazole's effect persists for about 24-48 hours due to its longer half-life.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Amoxycillin is a beta-lactam antibiotic that inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial lysis and death. Tinidazole is a nitroimidazole that enters susceptible anaerobic microorganisms and protozoa, where its nitro group is reduced to reactive intermediates that damage DNA, causing cell death. Together, they provide broad coverage against aerobic and anaerobic bacteria as well as protozoa.

Mechanism Steps

1
Amoxycillin binds to penicillin-binding proteins: Amoxycillin attaches to penicillin-binding proteins on the bacterial cell membrane, inhibiting the transpeptidation step of cell wall synthesis.
2
Bacterial cell wall weakening and lysis: Without proper cross-linking, the bacterial cell wall becomes weak, and the cell bursts due to osmotic pressure, leading to bacterial death.
3
Tinidazole enters anaerobic organisms: Tinidazole diffuses into anaerobic bacteria and protozoa, where the low-oxygen environment allows its nitro group to be reduced.
4
DNA damage and cell death: The reduced tinidazole intermediates bind to DNA, causing strand breakage and inhibiting nucleic acid synthesis, resulting in cell death.

💡 How to Take tinimox tablet

Strength: Immediate-release tablet containing 500 mg amoxycillin and 300 mg tinidazole.

1Take the tablet with a full glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals, approximately every 12 hours.
5Complete the full course as prescribed by your doctor.
6Do not take with alcohol or alcohol-containing products.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally twice daily, approximately every 12 hours, with food. The duration of treatment depends on the type and severity of infection, typically ranging from 5 to 10 days. For specific infections like amoebic liver abscess, therapy may extend to 5-10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing.
Elderly DosageElderly patients may have reduced renal function and may require dose adjustment. Use with caution and monitor renal function. Consult a doctor for individualized dosing.
Renal ImpairmentIn patients with renal impairment (creatinine clearance less than 30 mL/min), dose adjustment may be necessary. Amoxycillin dose may need to be reduced or interval increased. Tinidazole pharmacokinetics are not significantly altered in renal impairment, but caution is advised. Consult a doctor for specific dosing.
Hepatic ImpairmentIn patients with severe hepatic impairment, tinidazole metabolism may be prolonged. Dose reduction may be considered. Monitor liver function. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is two tablets (1000 mg amoxycillin + 600 mg tinidazole) per day, unless otherwise prescribed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Meals
Take with food
Reduces stomach upset and improves absorption.
Alcohol
Avoid completely
Can cause disulfiram-like reaction.

⏰ What to Do If You Miss a Dose

📌 Less than 6 hours since missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 6 hours since missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of tinimox tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Metallic taste (Common (5-10%))
Usually temporary. Chewing sugar-free gum or rinsing mouth may help.
Diarrhea (Common (5-10%))
Stay hydrated. If severe or bloody, contact your doctor.
Headache (Common (5-10%))
Rest and hydrate. If persistent, consult your doctor.
Abdominal pain (Common (5-10%))
Take with food. If severe, seek medical advice.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, throat, difficulty breathing, or rash.
Disulfiram-like reaction with alcohol (Uncommon (0.1-1%))
Avoid alcohol completely. If reaction occurs (severe nausea, vomiting, flushing, rapid heart rate), seek immediate medical attention.
Blood dyscrasias (e.g., leukopenia, thrombocytopenia) (Rare (<0.1%))
Report unusual bruising, bleeding, or signs of infection to your doctor promptly.
Peripheral neuropathy (Rare (<0.1%))
If you experience numbness, tingling, or burning in hands or feet, stop the medicine and consult your doctor.
Seizures (Rare (<0.1%))
Seek immediate medical attention if seizures occur.

⚠️ Rare Side Effects

Pseudomembranous colitis
Seek medical attention if you develop severe, persistent diarrhea with blood or mucus.
Liver enzyme elevation
Monitor liver function if prolonged use. Report yellowing of eyes or skin.
Interstitial nephritis
Report decreased urine output or swelling. Seek medical attention.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Methotrexate Major
Allopurinol Moderate
Oral contraceptives Moderate
Probenecid Moderate
Fluorouracil Moderate
Antacids Minor
Iron supplements Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Methotrexate
  • Allopurinol

⚡ Moderate Interactions

  • Oral contraceptives
  • Probenecid
  • Fluorouracil

🍷 Alcohol Interaction

Alcohol must be strictly avoided while taking this medicine and for at least 72 hours after the last dose. Tinidazole can cause a disulfiram-like reaction characterized by severe nausea, vomiting, flushing, headache, and rapid heartbeat. This reaction can be dangerous and requires immediate medical attention if it occurs.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to amoxycillin, tinidazole, other penicillins, or nitroimidazoles","History of blood dyscrasias","Active central nervous system disease (e.g., epilepsy)","First trimester of pregnancy","Severe hepatic impairment","Use of disulfiram within the past two weeks"]

⚠️ Warnings & Precautions

["Avoid alcohol during and for 72 hours after treatment.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Use with caution in patients with hepatic impairment; monitor liver function.","May cause peripheral neuropathy with prolonged use; monitor for numbness or tingling.","May cause seizures in patients with CNS disorders; use with caution.","Can cause superinfection with resistant organisms; monitor for new infections.","May reduce efficacy of oral contraceptives; use backup contraception.","Do not use for viral infections.","Complete the full course as prescribed."]

🤱 Lactation Safety

Amoxycillin is excreted in breast milk in small amounts and is generally considered safe. Tinidazole is also excreted in breast milk; because of potential adverse effects on the infant, breastfeeding should be interrupted during treatment and for 72 hours after the last dose. Consult your doctor.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and abdominal pain. In severe cases, seizures or blood dyscrasias may occur. There is no specific antidote. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Hemodialysis may remove amoxycillin but not tinidazole. Contact a poison control center or emergency department immediately if overdose is suspected.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Complete the full course to prevent recurrence and resistance. Avoid all alcohol-containing products during treatment and for at least 72 hours after the last dose, as this can cause a severe reaction. Take the tablet with food and a full glass of water to reduce stomach upset. Inform your doctor if you have kidney or liver problems, as dose adjustments may be needed. Do not share this medicine with others. If you miss a dose, take it as soon as you remember, but if it is almost time for the next dose, skip the missed dose and continue your regular schedule. Do not double the dose. Store at room temperature away from moisture and heat. Keep out of reach of children. If you experience signs of an allergic reaction such as rash, swelling, or difficulty breathing, seek emergency medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal and hepatic function, increasing the risk of side effects. Dose adjustment may be needed. Monitor for signs of toxicity and ensure adequate hydration.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. Tinidazole is not recommended in the first trimester. Use effective contraception during treatment and for at least 72 hours after the last dose.

🏥 Post-Surgery Considerations

This medicine may be prescribed after surgery to prevent or treat intra-abdominal infections. Follow your surgeon's instructions carefully. Monitor for signs of infection and report any unusual symptoms.

🦷 Dental Procedures

This medicine is often prescribed before or after dental procedures for dental abscesses. Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain good hygiene to prevent infections.
🥗
Stay well hydrated, especially if you have diarrhea.
😴
Eat a balanced diet to support your immune system.
💧
Avoid alcohol completely during treatment.
🧘
Get adequate rest to help your body fight infection.
🌞
Complete the full course of antibiotics as prescribed.

🏋️ Exercise Considerations

This medicine may cause dizziness or rarely seizures. Avoid strenuous exercise or driving if you feel dizzy or unwell. Light activity is generally safe, but listen to your body and rest if needed.

🥗 Diet Recommendations

Take the medicine with food to reduce stomach upset.
Include probiotics like yogurt to maintain gut health, but separate by 2 hours from the antibiotic.
Stay well hydrated with water and clear fluids.
Avoid alcohol and alcohol-containing foods.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, headache, or metallic taste, which can affect your ability to drive or operate machinery. Avoid driving if you feel dizzy or unwell. Most people can continue their normal activities, but take precautions as needed.

🛑 When to Stop This Medicine

Stop taking this medicine only after completing the full prescribed course, unless your doctor advises otherwise. If you experience severe side effects such as allergic reactions, seizures, or severe diarrhea, stop immediately and seek medical attention. Do not stop early even if you feel better, as this can lead to recurrence and resistance.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to superinfection with resistant organisms, fungal overgrowth, and rarely, peripheral neuropathy or blood dyscrasias. It should only be used for the prescribed duration. Regular monitoring of liver and kidney function may be needed if prolonged therapy is required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Metronidazole-based combinations

Alternative antiprotozoal and antibacterial combinations may be used if allergic to tinidazole.

Evidence: Well-established
Amoxycillin alone

For bacterial infections without protozoal involvement.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the efficacy of live bacterial vaccines like typhoid vaccine. Avoid live vaccines during treatment and for at least 24 hours after the last dose. Consult your doctor for specific advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, maintain the 12-hour dosing interval as closely as possible; consult your doctor for specific advice. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with recurrent vaginal discharge and itching
She was diagnosed with bacterial vaginosis and prescribed this medicine. She took it twice daily with food for 7 days. Her symptoms improved within 3 days, and she completed the course. She was advised to avoid alcohol and use backup contraception.
💡 Lesson: Completing the full course and following safety advice leads to successful treatment.
👤 A 50-year-old man with a dental abscess and severe tooth pain
He was prescribed this medicine before a root canal. He took it regularly and noticed reduced pain and swelling within 2 days. He avoided alcohol and completed the 5-day course. The dental procedure was successful.
💡 Lesson: This medicine is effective as an adjunct to dental procedures when taken as prescribed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2-3 days, but you must complete the full course as prescribed.

Q: Can I take this medicine with food?

A: Yes, take it with food to reduce stomach upset.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for the next dose, skip it and continue your schedule. Do not double dose.

Q: Is it safe to drink alcohol while taking this medicine?

A: No, alcohol can cause a severe reaction. Avoid it completely during and for 72 hours after treatment.

Q: Can I take this medicine during pregnancy?

A: It is not recommended in the first trimester. Consult your doctor for risk-benefit assessment.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for tinimox tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure any infection.
    Fact: It is effective only against susceptible bacteria and protozoa. It does not treat viral infections like colds or flu.
  • Myth: You can stop taking it once you feel better.
    Fact: You must complete the full course to prevent recurrence and resistance.
  • Myth: It is safe to drink alcohol while on this medicine.
    Fact: Alcohol can cause a severe disulfiram-like reaction. Avoid completely.
  • Myth: It is safe to take during early pregnancy.
    Fact: Tinidazole is not recommended in the first trimester. Consult your doctor.

🔄 Alternative Options

Generic Alternatives

  • Amoxycillin + Tinidazole combination tablets from other manufacturers

Brand Alternatives

  • Moxikind TZ Tablet

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Amoxycillin 500mg + Tinidazole 300mg","uses":"Mixed bacterial and protozoal infections","notes":"Combination product"},{"medicine":"Amoxycillin + Clavulanic acid","composition":"Amoxycillin 500mg + Clavulanic acid 125mg","uses":"Resistant bacterial infections","notes":"No antiprotozoal coverage"},{"medicine":"Metronidazole + Amoxycillin","composition":"Metronidazole 400mg + Amoxycillin 500mg","uses":"Similar indications","notes":"Metronidazole has shorter half-life"}]

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