Tin Tin 150 mg/1000 mg Kit - Fluconazole (150mg) + Tinidazole (1000mg) medicine

Azostat 150 Mg/1000 Mg Kit: Complete Medicine Guide

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🏭 Orange Healthcare Pvt Ltd 📦 packet of 1 Kit 💊 Allopathy 📅 Updated: Oct 28, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Fluconazole: Use only if clearly needed; high doses may be harmful. Tinidazole: Avoid in first trimester; use with caution in second and third trimesters. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 28, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe allergic reaction: swelling of face, lips, or throat, difficulty breathing.
  • Signs of liver problems: yellowing of skin or eyes, dark urine, severe fatigue.
  • Unusual bleeding or bruising.
  • Severe abdominal pain or persistent vomiting.
  • Seizures or loss of consciousness.
  • Palpitations or fainting.

If experiencing severe symptoms, call emergency services immediately.

What is Tin Tin 150 mg/1000 mg Kit used for?

This medicine is a combination kit of fluconazole 150 mg and tinidazole 1000 mg used to treat mixed vaginal infections caused by fungi and protozoa. It is taken orally, usually as a single dose or short course, and alcohol must be avoided.

  • Generic Name: Fluconazole (150mg) + Tinidazole (1000mg)
  • Manufacturer: Orange Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Tin Tin 150 mg/1000 mg Kit के बारे में (Hindi Summary)

उपयोग: यह दवा फ्लुकोनाज़ोल 150 मिलीग्राम और टिनिडाज़ोल 1000 मिलीग्राम का संयोजन है, जिसका उपयोग योनि में होने वाले मिश्रित संक्रमणों (फंगल और प्रोटोज़ोआ) के इलाज के लिए किया जाता है। यह डिस्चार्ज, खुजली और जलन को कम करने में मदद करती है। इसे डॉक्टर के निर्देशानुसार ही लें और शराब का सेवन बिल्कुल न करें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, मुँह में धातु जैसा स्वाद, पेट दर्द, सिरदर्द और चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे पर सूजन, सांस लेने में कठिनाई, पीलिया या असामान्य रक्तस्राव हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। उपचार के दौरान और अंतिम खुराक के 72 घंटे बाद तक शराब न पिएं। अगर आपको लीवर या किडनी की समस्या है, या आप गर्भवती हैं, तो डॉक्टर को बताएं। कोर्स पूरा करें, बीच में न छोड़ें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 Tin Tin 150 mg/1000 mg Kit Uses & Benefits

[{"condition":"Mixed vaginal infections (candidiasis + trichomoniasis)","description":"This kit treats both fungal and protozoal causes of vaginal discharge and discomfort.","evidence":"Well-established"},{"condition":"Bacterial vaginosis with concurrent fungal infection","description":"Tinidazole targets anaerobic bacteria while fluconazole addresses Candida.","evidence":"Moderate"},{"condition":"Trichomoniasis with suspected candidiasis","description":"Used when laboratory tests indicate both organisms.","evidence":"Limited"}]

Off-label uses: [{"condition":"Giardiasis with fungal overgrowth","description":"Occasionally prescribed when both conditions are confirmed.","evidence":"Limited"}]

Primary treatment for: Mixed vaginal infections

Also treats: Trichomoniasis, Candidiasis, Bacterial vaginosis

📋 Drug Information

Generic Name(s)Fluconazole (150mg) + Tinidazole (1000mg)
Brand NameTin Tin 150 mg/1000 mg Kit
ManufacturerOrange Healthcare Pvt Ltd
Packaging / Formpacket of 1 Kit (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Avoid alcohol completely during treatment and for 72 hours after the last dose.
3
Complete the full course as prescribed, even if symptoms improve.
4
Inform your doctor if you are taking blood thinners, seizure medicines, or diabetes drugs.
5
Use effective contraception during treatment if you are of childbearing age.
6
Report any unusual bleeding, bruising, or yellowing of eyes immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Vaginal discharge
This medicine is commonly prescribed for mixed vaginal infections.
Likely Use
✅
Itching
Helps relieve itching due to fungal or protozoal infection.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionFluconazole is well absorbed orally, with bioavailability over 90%. Tinidazole is also rapidly and completely absorbed from the gastrointestinal tract.
DistributionFluconazole distributes widely to body fluids including cerebrospinal fluid, saliva, and vaginal secretions. Tinidazole distributes widely to tissues and crosses the blood-brain barrier.
Protein BindingFluconazole is approximately 11-12% protein bound. Tinidazole is about 12% protein bound.
MetabolismFluconazole undergoes minimal hepatic metabolism, with about 11% metabolized. Tinidazole is metabolized in the liver, primarily by CYP3A4.
Half-LifeFluconazole half-life is approximately 30 hours in adults with normal renal function. Tinidazole half-life is about 12-14 hours.
ExcretionFluconazole is excreted primarily unchanged in urine (about 80%). Tinidazole is excreted in urine and feces, partly as metabolites.
BioavailabilityFluconazole oral bioavailability is over 90%. Tinidazole oral bioavailability is approximately 100%.
Onset of ActionFluconazole onset is within 1-2 hours; tinidazole onset is within 1-2 hours.
Peak Plasma TimeFluconazole peak plasma time is 1-2 hours. Tinidazole peak plasma time is about 2 hours.
Duration of ActionFluconazole duration is about 24 hours or more due to long half-life. Tinidazole duration is about 12-24 hours.

How It Works

Fluconazole inhibits fungal cytochrome P450-dependent 14-alpha-demethylase, blocking ergosterol synthesis and damaging the fungal cell membrane. Tinidazole enters anaerobic organisms and is reduced to reactive intermediates that bind DNA, causing strand breakage and inhibiting nucleic acid synthesis.

Mechanism Steps

1
Fluconazole uptake: Fluconazole is taken up by fungal cells and accumulates intracellularly.
2
Ergosterol synthesis inhibition: It inhibits 14-alpha-demethylase, leading to depletion of ergosterol and accumulation of toxic sterols.
3
Cell membrane damage: The altered membrane becomes permeable, causing leakage of cellular contents and fungal death.
4
Tinidazole activation: Tinidazole diffuses into anaerobic organisms and is reduced by ferredoxin-like proteins.
5
DNA disruption: The reduced intermediates bind to DNA, causing strand breakage and inhibiting replication.

💡 How to Take Tin Tin 150 mg/1000 mg Kit

Strength: Kit containing fluconazole 150 mg tablet and tinidazole 1000 mg tablet.

1Take the tablets with a full glass of water.
2Take with food to reduce stomach upset.
3Swallow whole; do not crush or chew.
4Avoid alcohol completely.
5Complete the full course as prescribed.

Dosage Information

Adult DosageThe usual adult dose is one kit taken as directed by your doctor. Typically, the fluconazole component is taken as a single 150 mg dose, and tinidazole 1000 mg is taken as a single dose or once daily for 2-5 days depending on the infection. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Use with caution and monitor for side effects.
Renal ImpairmentFluconazole dose should be reduced in renal impairment. Tinidazole dose may not require adjustment but use with caution.
Hepatic ImpairmentUse with caution in hepatic impairment. Dose reduction may be necessary for tinidazole.
Maximum Daily DoseFluconazole: 150 mg as a single dose for vaginal candidiasis; higher doses for other indications. Tinidazole: 2000 mg per day for certain infections. Do not exceed prescribed dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid completely
Can cause disulfiram-like reaction.
Grapefruit
Avoid
May increase fluconazole levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Tin Tin 150 mg/1000 mg Kit

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persistent, consult your doctor.
Metallic taste (Common (5-10%))
Usually temporary. Chewing sugar-free gum may help.
Headache (Common (5-10%))
Rest and stay hydrated. Consult if severe.
Dizziness (Uncommon (1-5%))
Avoid driving until you know how it affects you.
Abdominal pain (Uncommon (1-5%))
Take with meals. Consult if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical help immediately if you experience swelling of face, lips, or throat, or difficulty breathing.
Liver toxicity (Rare (<0.1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Blood disorders (e.g., leukopenia) (Rare (<0.1%))
Inform your doctor if you develop unusual bruising, bleeding, or frequent infections.
Seizures (Very rare (<0.01%))
Seek immediate medical attention if seizures occur.

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Seek emergency care for rash, blisters, or peeling skin.
QT prolongation
Report palpitations or fainting to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
Phenytoin Major
Cyclosporine Major
Rifampicin Moderate
Sulfonylureas Moderate
Statins Moderate
Antacids Minor
Cimetidine Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Phenytoin
  • Cyclosporine

⚡ Moderate Interactions

  • Rifampicin
  • Sulfonylureas
  • Statins

🍷 Alcohol Interaction

Alcohol must be strictly avoided during treatment with this medicine and for at least 72 hours after the last dose. Tinidazole can cause a disulfiram-like reaction with symptoms such as severe nausea, vomiting, flushing, headache, and rapid heartbeat. This reaction can be dangerous.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to fluconazole, tinidazole, or other azoles/nitroimidazoles","First trimester of pregnancy","Severe liver disease","Alcohol use during treatment","Concurrent use with disulfiram"]

⚠️ Warnings & Precautions

["Avoid alcohol during and for 72 hours after treatment.","Use effective contraception during treatment.","Caution in patients with liver or kidney impairment.","May cause dizziness; avoid driving until you know how it affects you.","Inform your doctor if you have a history of seizures.","Do not use for viral infections."]

🤱 Lactation Safety

Fluconazole and tinidazole are excreted in breast milk. Consult your doctor before breastfeeding. Formula feeding may be recommended during treatment.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, and dizziness. Seek immediate medical attention. Treatment is supportive and symptomatic. Dialysis may be considered for fluconazole overdose.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not share it with others. Avoid alcohol completely during treatment and for three days after the last dose. Inform your doctor if you have liver or kidney problems, or if you are taking blood thinners, seizure medicines, or diabetes drugs. Use effective contraception during treatment if you are of childbearing age. Do not stop the course early even if you feel better.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function; dose adjustment of fluconazole may be needed. Monitor for side effects closely.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It is generally avoided in the first trimester. Use effective contraception during treatment.

🏥 Post-Surgery Considerations

Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics and other medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with certain antibiotics or painkillers used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Maintain good genital hygiene.
🥗
Wear cotton underwear and avoid tight clothing.
😴
Avoid douching and scented products.
💧
Practice safe sex to prevent reinfection.
🧘
Complete the full course of treatment.
🌞
Stay hydrated and eat a balanced diet.

🏋️ Exercise Considerations

If you experience dizziness or fatigue, avoid strenuous exercise until you know how the medicine affects you.

🥗 Diet Recommendations

Include probiotics like yogurt to support gut health.
Avoid alcohol completely.
Stay well hydrated.
Eat a balanced diet rich in fruits and vegetables.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to rest if you feel unwell.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full prescribed course even if you feel better. If you experience severe side effects, contact your doctor immediately.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended unless prescribed for specific chronic infections. Prolonged use may increase risk of liver toxicity, blood disorders, and fungal resistance. Regular monitoring of liver and kidney function may be required.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

Can help restore healthy vaginal flora.

Evidence: Limited
Topical antifungals

For fungal infections only, not protozoal.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor for routine vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with vaginal discharge and itching
She was prescribed this kit for mixed infection. She took the tablets with food as directed and avoided alcohol. Her symptoms improved within 3 days. She completed the course and had no recurrence.
💡 Lesson: Taking the medicine with food and completing the course leads to better outcomes.
👤 A 45-year-old man with trichomoniasis and suspected fungal infection
He was given this kit. He experienced mild nausea and metallic taste, which subsided after taking it with meals. He was advised to avoid alcohol and did so. His infection resolved completely.
💡 Lesson: Mild side effects are common but manageable; adherence to instructions is key.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 1-3 days, but complete the full course as prescribed.

Q: Can I take it with other medicines?

A: Inform your doctor about all medicines you take, especially blood thinners, seizure medicines, and diabetes drugs.

Q: Is it safe during pregnancy?

A: Consult your doctor. It is generally avoided in the first trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Tin Tin 150 mg/1000 mg Kit

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: It can cure any vaginal infection.
    Fact: It only works for specific fungal and protozoal infections; bacterial vaginosis may require different treatment.
  • Myth: You can drink alcohol while taking it.
    Fact: Alcohol can cause a severe reaction and must be avoided.

🔄 Alternative Options

Generic Alternatives

  • Fluconazole 150 mg + Tinidazole 1000 mg kit

Brand Alternatives

  • Azostat 150 mg/1000 mg kit

📊 Comparison with Similar Medicines

[{"medicine":"Fluconazole alone","difference":"Only treats fungal infections, not protozoal."},{"medicine":"Tinidazole alone","difference":"Only treats protozoal/anaerobic infections, not fungal."}]

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