tempol syrup - Ibuprofen (NA) + Paracetamol (NA) medicine

Acogesic Capsule: Complete Medicine Guide

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🏭 Megha Healthcare Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. Ibuprofen is generally avoided in the third trimester due to risk of premature closure of ductus arteriosus. Paracetamol is considered relatively safe in pregnancy when used as directed. Consult your doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for individual components; combination evidence is supportive.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is tempol syrup used for?

This medicine is a combination of ibuprofen and paracetamol used for short-term relief of moderate to severe pain and fever. It works by reducing inflammation and blocking pain signals. Take it with food and do not exceed the recommended dose.

  • Generic Name: Ibuprofen (NA) + Paracetamol (NA)
  • Manufacturer: Megha Healthcare Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 tempol syrup के बारे में (Hindi Summary)

उपयोग: यह दवा इबुप्रोफेन और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर दर्द और बुखार से राहत के लिए किया जाता है। यह दांत दर्द, मांसपेशियों के दर्द, सिरदर्द, और सर्जरी के बाद के दर्द में प्रभावी है। यह सूजन को कम करने और दर्द को कम करने में मदद करती है। इसे भोजन के साथ लें और डॉक्टर की सलाह के बिना लंबे समय तक न लें।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, और चक्कर आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें पेट में रक्तस्राव, गुर्दे की समस्या, और यकृत की क्षति शामिल हो सकती है। यदि आपको काला मल, खून की उल्टी, या गंभीर पेट दर्द हो तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को हमेशा भोजन या दूध के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें क्योंकि इससे पेट में रक्तस्राव और यकृत की क्षति का खतरा बढ़ सकता है। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको गुर्दे या यकृत की बीमारी है, तो डॉक्टर से सलाह लें। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 tempol syrup Uses & Benefits

[{"condition":"Dental pain","description":"Relieves moderate to severe toothache and pain after dental procedures.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"Reduces pain and inflammation in conditions like sprains, strains, and back pain.","evidence":"Well-established"},{"condition":"Headache","description":"Provides relief from tension headaches and mild migraines.","evidence":"Well-established"},{"condition":"Fever","description":"Lowers elevated body temperature due to infections or other causes.","evidence":"Well-established"},{"condition":"Post-operative pain","description":"Manages pain after minor surgical procedures.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Menstrual cramps","description":"Sometimes used to relieve dysmenorrhea, though not specifically approved for this combination.","evidence":"Limited"},{"condition":"Migraine","description":"May be used off-label for acute migraine attacks, but not first-line.","evidence":"Limited"}]

Primary treatment for: Pain and fever

Also treats: Dental pain, Musculoskeletal pain, Headache, Post-operative pain

📋 Drug Information

Generic Name(s)Ibuprofen (NA) + Paracetamol (NA)
Brand Nametempol syrup
ManufacturerMegha Healthcare Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food or milk to minimize stomach irritation.
2
Do not exceed the recommended dose or duration without consulting your doctor.
3
Avoid alcohol while taking this medicine to prevent gastrointestinal bleeding and liver damage.
4
If you have a history of ulcers, kidney disease, or heart problems, inform your doctor before taking this medicine.
5
Do not take other pain relievers or cold medicines containing paracetamol or ibuprofen without checking with your doctor.
6
If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine.
7
Report any unusual bleeding, bruising, or yellowing of eyes to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Dental pain
This medicine is commonly prescribed for this.
Likely Use
Fever
This medicine is used to reduce fever.
Likely Use
Chronic joint pain
This medicine can provide relief.
Likely Use
Chest pain
This medicine is not for chest pain; seek emergency care.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionIbuprofen is rapidly absorbed from the gastrointestinal tract, with peak plasma levels occurring 1-2 hours after oral administration. Paracetamol is also rapidly absorbed, with peak levels within 0.5-2 hours. Food may delay absorption slightly but does not significantly reduce the extent.
DistributionBoth drugs distribute widely throughout the body. Ibuprofen is highly protein-bound, while paracetamol has a lower protein binding. Ibuprofen crosses the placenta and is excreted in breast milk. Paracetamol also crosses the placenta and is excreted in breast milk.
Protein BindingIbuprofen is approximately 99% bound to plasma proteins. Paracetamol is about 10-25% bound to plasma proteins.
MetabolismIbuprofen is metabolized in the liver by CYP2C9 to inactive metabolites. Paracetamol is metabolized in the liver primarily by glucuronidation and sulfation, with a small fraction metabolized by CYP2E1 to a toxic intermediate (NAPQI) that is normally detoxified by glutathione.
Half-LifeThe elimination half-life of ibuprofen is approximately 2 hours. The elimination half-life of paracetamol is approximately 2-3 hours.
ExcretionIbuprofen metabolites are excreted primarily in the urine. Paracetamol metabolites are excreted in the urine, with about 90% excreted within 24 hours.
BioavailabilityIbuprofen has a bioavailability of approximately 80-90%. Paracetamol has a bioavailability of approximately 80-100%.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimeIbuprofen peak plasma concentration occurs at 1-2 hours. Paracetamol peak plasma concentration occurs at 0.5-2 hours.
Duration of ActionPain relief lasts approximately 4-6 hours.

How It Works

This medicine combines two active ingredients with different mechanisms. Ibuprofen is a non-selective cyclooxygenase (COX) inhibitor that blocks both COX-1 and COX-2 enzymes, reducing prostaglandin synthesis and thereby decreasing pain, inflammation, and fever. Paracetamol acts primarily in the central nervous system, where it inhibits prostaglandin synthesis and may also modulate pain perception through other pathways. The combination provides additive analgesic and antipyretic effects.

Mechanism Steps

1
COX inhibition by ibuprofen: Ibuprofen reversibly inhibits cyclooxygenase enzymes, blocking the conversion of arachidonic acid to prostaglandins.
2
Reduced prostaglandin synthesis: Lower prostaglandin levels decrease inflammation, pain, and fever.
3
Central action of paracetamol: Paracetamol acts in the brain to inhibit prostaglandin synthesis and modulate pain pathways.
4
Additive analgesic effect: The two mechanisms complement each other, providing enhanced pain relief.

💡 How to Take tempol syrup

Strength: Capsule containing ibuprofen 400 mg and paracetamol 500 mg (typical strength; actual strength may vary).

1Take this medicine exactly as prescribed by your doctor.
2Swallow the capsule whole with a glass of water.
3Take with food or milk to reduce stomach upset.
4Do not crush, chew, or break the capsule.
5Do not take more than the recommended dose.
6If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose is one capsule taken orally every 4 to 6 hours as needed for pain or fever. Do not exceed 6 capsules in 24 hours. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Take with food or milk to reduce stomach upset.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially gastrointestinal bleeding and kidney problems. Use the lowest effective dose for the shortest duration. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney impairment. Dose reduction may be necessary. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with liver impairment. Dose reduction may be necessary. Consult your doctor.
Maximum Daily DoseMaximum daily dose is 6 capsules in 24 hours. Do not exceed.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of stomach bleeding and liver damage.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of tempol syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If persistent, consult your doctor.
Stomach pain (Common (5-10%))
Take with food or milk. Avoid alcohol. If severe, contact your doctor.
Heartburn (Common (5-10%))
Take with food. Avoid lying down immediately after taking. Consult if persistent.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice black or bloody stools, vomiting blood, or severe abdominal pain.
Kidney problems (Rare (<0.1%))
Report decreased urine output, swelling, or fatigue to your doctor immediately.
Liver damage (Rare (<0.1%))
Seek medical help if you experience yellowing of skin or eyes, dark urine, or severe fatigue.
Severe allergic reaction (Rare (<0.1%))
Call emergency services if you have swelling of face, lips, or throat, difficulty breathing, or rash.

⚠️ Rare Side Effects

Anaphylaxis
Seek emergency medical help immediately.
Stevens-Johnson syndrome
Seek immediate medical attention if you develop a rash with blisters or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
ACE inhibitors Major
Corticosteroids Moderate
Diuretics Moderate
SSRIs Moderate
Antacids Minor
Alcohol Moderate

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • ACE inhibitors

⚡ Moderate Interactions

  • Corticosteroids
  • Diuretics
  • SSRIs

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding and can potentiate liver damage, especially with paracetamol.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to ibuprofen, paracetamol, or any component","History of asthma, urticaria, or allergic reaction to aspirin or other NSAIDs","Active or history of peptic ulcer or gastrointestinal bleeding","Severe kidney impairment","Severe liver impairment","Heart failure (severe)","Third trimester of pregnancy","Children under 12 years (unless directed by doctor)"]

⚠️ Warnings & Precautions

["Take with food to reduce stomach irritation.","Do not exceed recommended dose or duration.","Avoid alcohol.","Use with caution in elderly patients.","Consult doctor if you have a history of ulcers, kidney or liver disease, high blood pressure, or heart disease.","Do not use for more than 3 days for fever or 10 days for pain without medical advice.","May cause dizziness; avoid driving if affected."]

🤱 Lactation Safety

Ibuprofen and paracetamol are excreted in breast milk in small amounts. Short-term use is generally considered compatible with breastfeeding. Consult your doctor.

💊 Overdose Management

Overdose can cause severe liver damage, kidney failure, and gastrointestinal bleeding. Seek emergency medical attention immediately. Treatment may include activated charcoal, gastric lavage, and administration of acetylcysteine for paracetamol toxicity. Supportive care for ibuprofen toxicity.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Additional Safety Advice

General Safety

Always take this medicine with food or milk to reduce stomach irritation. Do not exceed the recommended dose or duration without consulting your doctor. Avoid alcohol while taking this medicine as it increases the risk of stomach bleeding and liver damage. Inform your doctor if you have a history of ulcers, kidney or liver disease, high blood pressure, or heart problems. Do not take other pain relievers or cold medicines containing paracetamol or ibuprofen without checking with your doctor. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before using this medicine. Keep out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney problems, and cardiovascular events. Use the lowest effective dose for the shortest duration. Monitor kidney and liver function.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are planning pregnancy. Ibuprofen may affect ovulation and is generally avoided in the third trimester.

🏥 Post-Surgery Considerations

This medicine can be used for post-operative pain as prescribed by your surgeon. Inform your surgeon about all medicines you are taking.

🦷 Dental Procedures

This medicine can be used for dental pain. Inform your dentist if you are taking this medicine before any dental procedure.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming.
😴
Practice good posture.
💧
Include anti-inflammatory foods in your diet.
🧘
Get adequate sleep.
🌞
Stay hydrated.

🏋️ Exercise Considerations

Avoid strenuous exercise if you have pain or inflammation. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods
Reduce processed food intake
Stay well hydrated
Avoid alcohol

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you. It may affect your ability to concentrate.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 3 days for fever or 10 days for pain, or if you experience any serious side effects.

📅 Long-Term Use Effects

Long-term use of this medicine can increase the risk of gastrointestinal bleeding, kidney problems, liver damage, and cardiovascular events. Regular monitoring of kidney and liver function may be required. Use the lowest effective dose for the shortest duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain.

Evidence: Well-established
Heat/cold therapy

May help relieve localized pain and inflammation.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are established. Consult your doctor if you have concerns.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and avoid extreme heat. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for controlled substances.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 30-year-old woman with severe toothache
Took this medicine for dental pain and got relief within 30 minutes. She was advised to take it with food and not to exceed the recommended dose.
💡 Lesson: This medicine provides rapid relief for acute pain when taken as directed.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts relieving pain within 30-60 minutes after taking it.

Q: Can I take it on an empty stomach?

A: It is best taken with food or milk to reduce stomach upset.

Q: Is it safe during pregnancy?

A: Consult your doctor. It is generally avoided in the third trimester.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for tempol syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is safe to take on an empty stomach.
    Fact: It should be taken with food to reduce stomach irritation.
  • Myth: This medicine can be taken indefinitely for chronic pain.
    Fact: Long-term use increases risk of side effects. Use only as prescribed.
  • Myth: This medicine is safe to combine with other pain relievers.
    Fact: Combining with other NSAIDs or paracetamol can increase risk of toxicity.

🔄 Alternative Options

Generic Alternatives

  • Ibuprofen + Paracetamol combination (generic)

Brand Alternatives

  • Combiflam
  • Brufen Plus
  • Ibugesic Plus

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Ibuprofen + Paracetamol","onset":"30-60 minutes","duration":"4-6 hours"},{"medicine":"Diclofenac + Paracetamol","composition":"Diclofenac + Paracetamol","onset":"30-60 minutes","duration":"4-6 hours"}]

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