Takoda H 80mg/12.5mg Tablet - Telmisartan (80mg) + Hydrochlorothiazide (12.5mg) medicine

Angiotel H 80mg/12.5mg Tablet: Complete Guide to Uses, Side Effects, and Safety

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🏭 MVD Pharmaceuticals Pvt Ltd 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not recommended. This medicine can cause harm to the unborn baby, especially in the second and third trimesters. It is contraindicated in pregnancy. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for hypertension.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
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When to Call Your Doctor IMMEDIATELY

  • Swelling of the face, lips, throat, or tongue
  • Difficulty breathing or swallowing
  • Severe dizziness or fainting
  • Chest pain or irregular heartbeat
  • Decreased urine output or swelling in legs
  • Severe abdominal pain or vomiting
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is Takoda H 80mg/12.5mg Tablet used for?

This medicine is a combination of Telmisartan and Hydrochlorothiazide used to treat high blood pressure. It works by relaxing blood vessels and removing excess fluid from the body.

  • Generic Name: Telmisartan (80mg) + Hydrochlorothiazide (12.5mg)
  • Manufacturer: MVD Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Takoda H 80mg/12.5mg Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। इसमें टेल्मिसार्टन और हाइड्रोक्लोरोथियाजाइड दो सक्रिय तत्व होते हैं। टेल्मिसार्टन रक्त वाहिकाओं को आराम देकर रक्तचाप कम करता है, जबकि हाइड्रोक्लोरोथियाजाइड शरीर से अतिरिक्त नमक और पानी को बाहर निकालता है। यह दवा उन रोगियों के लिए है जिनका रक्तचाप एक दवा से नियंत्रित नहीं हो पाता। यह स्ट्रोक, दिल के दौरे और किडनी की समस्याओं का खतरा कम करने में मदद करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, थकान, मतली और बार-बार पेशाब आना शामिल हैं। कुछ लोगों को पैरों में सूजन या कमजोरी महसूस हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर चेहरे, होंठ, गले या जीभ में सूजन, सांस लेने में कठिनाई, या बहुत कम रक्तचाप हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। गर्भवती महिलाओं को यह दवा नहीं लेनी चाहिए। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। पर्याप्त पानी पिएं। पोटैशियम सप्लीमेंट बिना डॉक्टर की सलाह के न लें। नियमित रूप से रक्तचाप, किडनी फंक्शन और इलेक्ट्रोलाइट्स की जांच कराएं। दवा अचानक बंद न करें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 Takoda H 80mg/12.5mg Tablet Uses & Benefits

  • [{"condition":"Hypertension","description":"This medicine is used to lower high blood pressure in adults when treatment with a single agent is not sufficient.
  • It helps reduce the risk of stroke, heart attack, and kidney problems.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Hypertension

Also treats: Cardiovascular risk reduction, Stroke prevention, Heart attack prevention

📋 Drug Information

Generic Name(s)Telmisartan (80mg) + Hydrochlorothiazide (12.5mg)
Brand NameTakoda H 80mg/12.5mg Tablet
ManufacturerMVD Pharmaceuticals Pvt Ltd
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and light. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent blood levels.
2
Monitor your blood pressure regularly and keep a record to share with your doctor.
3
Stay hydrated, especially during hot weather or if you exercise heavily.
4
Avoid potassium supplements and salt substitutes unless prescribed by your doctor.
5
Report any swelling of the face, lips, or throat immediately.
6
Do not stop this medicine suddenly without consulting your doctor.
7
Inform your doctor if you experience muscle cramps, weakness, or irregular heartbeat.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
High blood pressure
This medicine is commonly prescribed for this.
Likely Use
❌
Swelling in legs
This medicine is not a primary treatment for edema but may be used if related to hypertension.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTelmisartan is rapidly absorbed after oral administration, with peak plasma concentrations reached 0.5 to 1 hour after dosing. Hydrochlorothiazide is also rapidly absorbed, with peak levels at about 1.5 to 2 hours. Food slightly reduces the bioavailability of telmisartan but does not significantly affect hydrochlorothiazide.
DistributionTelmisartan is highly bound to plasma proteins and has a large volume of distribution. Hydrochlorothiazide is distributed in extracellular fluid and does not cross the blood-brain barrier significantly. Both agents cross the placenta and are excreted in breast milk.
Protein BindingTelmisartan is greater than 99.5% bound to plasma proteins. Hydrochlorothiazide is about 40-70% bound to plasma proteins.
MetabolismTelmisartan is metabolized in the liver primarily by conjugation with glucuronic acid; no active metabolites are formed. Hydrochlorothiazide is not metabolized and is excreted unchanged in the urine.
Half-LifeTelmisartan has a terminal elimination half-life of approximately 24 hours. Hydrochlorothiazide has a half-life of about 5.6 to 14.8 hours.
ExcretionTelmisartan is excreted mainly in the feces via bile, with less than 1% excreted unchanged in urine. Hydrochlorothiazide is excreted almost entirely unchanged in the urine.
BioavailabilityTelmisartan has an absolute bioavailability of about 42-58%. Hydrochlorothiazide has a bioavailability of about 60-80%.
Onset of ActionThe antihypertensive effect of telmisartan begins within 1-2 hours after oral administration. Hydrochlorothiazide diuresis begins within 1-2 hours and peaks at about 4-6 hours.
Peak Plasma TimeTelmisartan peak plasma concentration occurs 0.5-1 hour after dosing. Hydrochlorothiazide peak plasma concentration occurs 1.5-2 hours after dosing.
Duration of ActionThe blood pressure-lowering effect of this medicine lasts for about 24 hours, allowing once-daily dosing.

How It Works

This medicine combines two antihypertensive agents with complementary mechanisms. Telmisartan selectively blocks angiotensin II type 1 (AT1) receptors, preventing angiotensin II from causing vasoconstriction and aldosterone release, which leads to reduced blood pressure and decreased sodium retention. Hydrochlorothiazide inhibits the sodium-chloride symporter in the distal convoluted tubule of the kidney, increasing excretion of sodium, chloride, and water, thereby reducing plasma volume and lowering blood pressure. The combination provides additive blood pressure reduction.

Mechanism Steps

1
Angiotensin II receptor blockade: Telmisartan binds to and blocks AT1 receptors, preventing angiotensin II from constricting blood vessels and stimulating aldosterone release.
2
Reduced aldosterone secretion: Blockade of AT1 receptors decreases aldosterone production, leading to less sodium and water retention and reduced potassium loss.
3
Diuretic action: Hydrochlorothiazide inhibits sodium reabsorption in the distal tubule, increasing excretion of sodium, chloride, and water.
4
Combined blood pressure reduction: The two mechanisms work together to lower blood pressure more effectively than either agent alone.

💡 How to Take Takoda H 80mg/12.5mg Tablet

Strength: Tablet containing Telmisartan 80 mg and Hydrochlorothiazide 12.5 mg.

1Take this medicine orally with a glass of water.
2You can take it with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take it at the same time each day to maintain consistent blood levels.
5If you miss a dose, follow the missed dose instructions.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose is one tablet once daily, taken orally with or without food. The dose may be adjusted by your doctor based on your blood pressure response and tolerance. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with kidney impairment. Not recommended if eGFR is less than 30 mL/min. Dose adjustment may be needed. Consult your doctor.
Hepatic ImpairmentUse with caution in patients with mild to moderate liver impairment. Not recommended in severe liver disease. Dose adjustment may be needed. Consult your doctor.
Maximum Daily DoseOne tablet of 80 mg/12.5 mg once daily. Do not exceed the recommended dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and improves tolerability.
High-sodium foods
Limit intake
Sodium can counteract the blood pressure-lowering effect.
Licorice
Avoid excessive consumption
May cause potassium loss and increase blood pressure.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of Takoda H 80mg/12.5mg Tablet

✅ Common Side Effects

Dizziness (Common (up to 10%))
Rise slowly from sitting or lying position. Avoid driving if dizzy. Consult doctor if persistent.
Headache (Common (up to 10%))
Usually resolves on its own. Take rest and stay hydrated. Consult doctor if severe.
Fatigue (Common (up to 10%))
Ensure adequate sleep. If fatigue interferes with daily activities, consult doctor.
Nausea (Common (up to 10%))
Take with food or milk. Consult doctor if nausea persists or worsens.
Increased urination (Common (up to 10%))
This is expected due to the diuretic. Take the dose earlier in the day to avoid nighttime urination.

🚨 Serious Side Effects

Angioedema (swelling of face, lips, throat, tongue) (Rare (<0.1%))
Seek immediate medical attention. Discontinue the medicine and call emergency services.
Severe hypotension (very low blood pressure) (Rare (<0.1%))
Lie down and elevate legs. Seek immediate medical help if symptoms include fainting, cold sweat, or blurred vision.
Kidney impairment (Uncommon (0.1-1%))
Report decreased urine output, swelling in legs, or fatigue. Regular monitoring of kidney function is advised.
Electrolyte imbalance (low potassium, low sodium) (Uncommon (0.1-1%))
Report muscle cramps, weakness, confusion, or irregular heartbeat. Blood tests can detect imbalances.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek emergency medical care immediately if you experience difficulty breathing, rash, or swelling.

⚠️ Rare Side Effects

Pancreatitis
Seek immediate medical attention if you have severe abdominal pain radiating to the back.
Jaundice
Report yellowing of skin or eyes to your doctor immediately.
Severe skin reactions (Stevens-Johnson syndrome)
Seek emergency care if you develop rash, blisters, or peeling skin.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Potassium supplements Major
Lithium Major
NSAIDs Major
ACE inhibitors Major
Corticosteroids Moderate
Diabetes medicines Moderate
Cholestyramine Moderate
Antacids Minor
Digoxin Minor

🚨 Major Interactions

  • Potassium supplements or potassium-sparing diuretics
  • Lithium
  • Nonsteroidal anti-inflammatory drugs (NSAIDs)
  • Angiotensin-converting enzyme (ACE) inhibitors

⚡ Moderate Interactions

  • Corticosteroids
  • Diabetes medicines (oral hypoglycemics and insulin)
  • Cholestyramine and colestipol

🍷 Alcohol Interaction

Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Breastfeeding","Severe kidney disease (eGFR

⚠️ Warnings & Precautions

["May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Monitor blood pressure regularly.","Avoid dehydration; drink adequate fluids.","Do not use potassium supplements without doctor's advice.","May increase blood sugar; monitor if diabetic.","May cause gout flare-ups; use with caution in gout patients.","May cause photosensitivity; use sunscreen.","Inform your doctor if you have lupus or are planning to become pregnant."]

🤱 Lactation Safety

This medicine is excreted in breast milk and may cause harm to the nursing infant. It is not recommended during breastfeeding. Consult your doctor for alternative treatments.

💊 Overdose Management

Overdose may cause severe hypotension, electrolyte imbalance, and dehydration. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic, including gastric lavage if recent ingestion, intravenous fluids, and monitoring of vital signs and electrolytes.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have a history of kidney disease, liver disease, heart failure, gout, lupus, or diabetes. Do not take this medicine if you are pregnant or planning to become pregnant, as it can harm the unborn baby. Avoid alcohol while taking this medicine because it can increase dizziness and low blood pressure. Drink plenty of water to stay hydrated, especially if you sweat a lot or have diarrhea or vomiting. Do not use potassium supplements or salt substitutes containing potassium without consulting your doctor. Regular monitoring of blood pressure, kidney function, and electrolyte levels is important. Do not stop taking this medicine suddenly without your doctor's advice. Keep all appointments with your healthcare provider.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of electrolyte imbalances. Start with a lower dose and monitor closely.

🤰 Pregnancy Planning (TTC)

This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid blood pressure fluctuations during the procedure.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine, as it may affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to help control blood pressure.
🥗
Reduce salt intake to less than 5 grams per day.
😴
Engage in regular physical activity like brisk walking for 30 minutes most days.
💧
Limit alcohol consumption and avoid smoking.
🧘
Manage stress through relaxation techniques like yoga or meditation.
🌞
Get adequate sleep of 7-8 hours per night.

🏋️ Exercise Considerations

Exercise is generally safe and beneficial while taking this medicine. However, avoid sudden strenuous activities if you are not used to them, as they may cause dizziness due to lowered blood pressure. Stay hydrated during exercise.

🥗 Diet Recommendations

Follow a low-sodium diet rich in fruits and vegetables.
Include potassium-rich foods like bananas, oranges, and spinach, but only if your doctor approves.
Limit processed and fried foods.
Choose whole grains and lean proteins.
Stay well hydrated with water.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, especially when you stand up quickly. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal daily activities with caution.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects like angioedema, severe hypotension, or kidney problems, your doctor may advise stopping the medicine and switching to an alternative.

📅 Long-Term Use Effects

Long-term use of this medicine may require regular monitoring of kidney function, electrolytes, and blood pressure. It is generally well-tolerated, but some patients may experience electrolyte imbalances or kidney issues. Regular follow-ups with your doctor are essential to adjust the dose and manage any side effects.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Diet, exercise, and stress reduction can help lower blood pressure and complement medicine.

Evidence: Well-established
Other antihypertensive classes

ACE inhibitors, calcium channel blockers, or beta-blockers may be used as alternatives.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from moisture. If traveling across time zones, consult your doctor about adjusting the dosing schedule. Keep enough supply for the entire trip and carry it in your hand luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 55-year-old man with a history of hypertension not controlled on a single medicine.
He was prescribed this medicine once daily. After 4 weeks, his blood pressure stabilized, and he reported feeling more energetic. He was advised to monitor his blood pressure at home and avoid alcohol.
💡 Lesson: Combination therapy can effectively control blood pressure when a single medicine is not enough. Regular monitoring and lifestyle changes are key.
👤 A 62-year-old woman with diabetes and hypertension.
She started this medicine and noticed increased urination initially, which subsided after a few weeks. Her blood pressure improved, but her blood sugar needed monitoring. She was advised to follow a low-sodium diet.
💡 Lesson: This medicine can affect blood sugar, so diabetic patients need regular monitoring. Lifestyle modifications enhance the effectiveness of treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts lowering blood pressure within 1-2 hours, but the full effect may take 2-4 weeks of regular use.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to take this medicine during pregnancy?

A: No, this medicine is not safe during pregnancy as it can harm the unborn baby. Consult your doctor for alternative treatment.

Q: Can I stop taking this medicine if my blood pressure is normal?

A: No, do not stop taking this medicine without consulting your doctor. High blood pressure often requires long-term treatment.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my diabetes medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for Takoda H 80mg/12.5mg Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be stopped once blood pressure is normal.
    Fact: High blood pressure often has no symptoms and requires long-term treatment. Stopping suddenly can cause a dangerous rise in blood pressure.
  • Myth: This medicine damages the kidneys.
    Fact: When used appropriately, this medicine can protect kidney function. However, regular monitoring is important.
  • Myth: Taking this medicine with alcohol is safe.
    Fact: Alcohol can increase the blood pressure-lowering effect and cause dizziness or fainting. It is best to avoid alcohol.

🔄 Alternative Options

Generic Alternatives

  • Telmisartan 80 mg + Hydrochlorothiazide 12.5 mg tablet

Brand Alternatives

  • Angiotel H 80mg/12.5mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Telmisartan 80 mg + Hydrochlorothiazide 12.5 mg","composition":"Telmisartan 80 mg + Hydrochlorothiazide 12.5 mg","strength":"80 mg/12.5 mg","dosage_form":"Tablet","route":"Oral","release_type":"Immediate release"},{"medicine":"Telmisartan 40 mg + Hydrochlorothiazide 12.5 mg","composition":"Telmisartan 40 mg + Hydrochlorothiazide 12.5 mg","strength":"40 mg/12.5 mg","dosage_form":"Tablet","route":"Oral","release_type":"Immediate release"}]

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