Bicalutamide 50 mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Yellowing of the skin or eyes (jaundice)
- Dark urine or pale stools
- Severe abdominal pain, especially in the upper right side
- Shortness of breath or difficulty breathing
- Chest pain or palpitations
- Swelling of the face, lips, or throat
- Unusual bleeding or bruising
- Sudden severe headache or vision changes
- Decreased urine output or swelling of the ankles
If experiencing severe symptoms, call emergency services immediately.
What is tabi tablet used for?
This medicine contains bicalutamide 50 mg, a non-steroidal antiandrogen used to treat prostate cancer. It works by blocking the effects of male hormones on cancer cells. It is taken orally once daily, usually in combination with other treatments. Regular monitoring of liver function is required.
- Generic Name: Bicalutamide (50mg)
- Manufacturer: Dr Reddy's Laboratories Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 tabi tablet के बारे में (Hindi Summary)
उपयोग: यह दवा बाइकलुटामाइड 50 मिलीग्राम युक्त एक टैबलेट है, जिसका उपयोग प्रोस्टेट कैंसर के इलाज में किया जाता है। यह पुरुष हार्मोन के प्रभाव को रोककर कैंसर कोशिकाओं की वृद्धि को धीमा करती है। इसका उपयोग अक्सर अन्य दवाओं या सर्जरी के साथ किया जाता है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और डॉक्टर की सलाह के बिना इसे शुरू या बंद नहीं करना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में स्तनों में कोमलता, स्तनों का बढ़ना, गर्म लहरें, कामेच्छा में कमी, नपुंसकता और थकान शामिल हैं। कुछ लोगों को मतली, दस्त, कब्ज या पेट में परेशानी हो सकती है। गंभीर दुष्प्रभावों में लीवर की समस्या, सांस लेने में कठिनाई, दिल की समस्या और एलर्जी प्रतिक्रिया शामिल हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक को कभी न बदलें और डॉक्टर की सलाह के बिना दवा बंद न करें। इसे हर दिन एक ही समय पर लें। गोली को पानी के साथ पूरा निगलें, चबाएं नहीं। इस दवा से चक्कर आ सकते हैं, इसलिए वाहन चलाने या मशीन चलाने में सावधानी बरतें। गर्भवती महिलाओं को इस दवा को छूने से भी बचना चाहिए। नियमित रूप से लीवर की जांच करवाएं। धूप और नमी से दूर, कमरे के तापमान पर इस दवा को रखें।
💊 tabi tablet Uses & Benefits
- [{"condition":"Metastatic prostate cancer","description":"This medicine is used in combination with a luteinising hormone-releasing hormone analogue or after surgical castration to treat metastatic prostate cancer.
- It helps block androgen effects and slows cancer growth.","evidence":"Well-established"},{"condition":"Locally advanced prostate cancer","description":"It may be used as part of treatment for locally advanced prostate cancer, often alongside other therapies, to reduce the risk of cancer progression.","evidence":"Well-established"},{"condition":"Non-metastatic prostate cancer","description":"In some patients with non-metastatic prostate cancer, this medicine may be prescribed as monotherapy when other treatments are not suitable.","evidence":"Established"},{"condition":"Hirsutism in women","description":"This medicine is sometimes used off-label to treat excessive hair growth in women, but this use is not approved and requires specialist supervision.","evidence":"Limited"}]
Off-label uses: [{"condition":"Hirsutism","description":"Bicalutamide has been used off-label for hirsutism in women, but it is not a standard first-line treatment and must only be used under specialist care.","evidence":"Limited"},{"condition":"Male pattern hair loss","description":"There is limited evidence for using this medicine in male pattern hair loss, and it is not an approved indication.","evidence":"Limited"}]
Primary treatment for: Prostate cancer
Also treats: Metastatic prostate cancer, Locally advanced prostate cancer, Non-metastatic prostate cancer
📋 Drug Information
| Generic Name(s) | Bicalutamide (50mg) |
| Brand Name | tabi tablet |
| Manufacturer | Dr Reddy's Laboratories Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Androgen receptor antagonist |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep the tablets in their original container, tightly closed, away from moisture and direct sunlight. Do not store in the bathroom. Keep out of reach of children. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture. Check the expiry date on the pack before use. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a non-steroidal antiandrogen. It works by binding to androgen receptors in the body and blocking the action of androgens such as testosterone and dihydrotestosterone. By preventing these hormones from stimulating prostate cancer cells, it helps to slow down the growth of the cancer. Unlike some other antiandrogens, it does not lower testosterone levels; instead, it stops testosterone from working at the receptor. This medicine is a pure antiandrogen with no other hormonal activity.
Mechanism Steps
💡 How to Take tabi tablet
Strength: Bicalutamide 50 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for prostate cancer is 50 mg once daily. It is often taken in combination with a luteinising hormone-releasing hormone analogue or after surgical castration. In some cases, a higher dose of 150 mg once daily may be used as monotherapy. The dose must be individualized by a qualified clinician based on the indication, age, weight, liver function, and kidney function. Do not change the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | No specific dose adjustment is required for elderly patients based on age alone. However, because elderly patients may have reduced liver or kidney function, they should be monitored closely for side effects. The dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is usually needed for patients with mild to moderate kidney impairment. For patients with severe kidney impairment, this medicine should be used with caution and under close medical supervision. The dose must be individualized by a qualified clinician. |
| Hepatic Impairment | This medicine should be used with caution in patients with mild to moderate liver impairment. In patients with severe liver impairment, the medicine is contraindicated. Liver function should be monitored regularly. The dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose is 150 mg, but this is only for specific indications and under specialist supervision. The usual dose is 50 mg once daily. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of tabi tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Cisapride | Major | |
| Terfenadine | Major | |
| Ketoconazole | Moderate | |
| Rifampicin | Moderate | |
| Verapamil | Moderate | |
| Simvastatin | Moderate | |
| Midazolam | Moderate | |
| Paracetamol | Minor | |
| Aspirin | Minor |
🚨 Major Interactions
- Warfarin
- Cisapride
- Terfenadine
- CYP3A4 inhibitors (e.g., ketoconazole, ritonavir)
⚡ Moderate Interactions
- CYP3A4 inducers (e.g., rifampicin, carbamazepine, phenytoin)
- Calcium channel blockers (e.g., verapamil, diltiazem)
- HMG-CoA reductase inhibitors (statins)
- Midazolam
🍷 Alcohol Interaction
Alcohol may increase the risk of dizziness, drowsiness, and liver problems when taken with this medicine. It is best to avoid alcohol or limit intake while taking this medicine. Discuss with your doctor about safe limits.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to bicalutamide or any component of the tablet","Use in women, especially during pregnancy or breastfeeding","Use in children","Severe liver impairment","Concomitant use with cisapride or terfenadine"]
⚠️ Warnings & Precautions
["This medicine should only be prescribed by a specialist experienced in treating prostate cancer.","Regular monitoring of liver function is essential because of the risk of severe liver injury.","Patients with heart disease should be monitored for signs of heart failure.","This medicine may cause dizziness or tiredness; avoid driving or operating machinery until you know how it affects you.","Do not handle this medicine if you are pregnant or may become pregnant.","Inform your doctor if you have a history of liver disease, heart disease, or lung disease.","This medicine may interact with many other medicines; always tell your doctor about all medicines you are taking.","Do not stop taking this medicine without consulting your doctor."]
🤱 Lactation Safety
This medicine is not for use in breastfeeding women. It is not known whether this medicine passes into breast milk, but because of its potential for serious harm to a nursing infant, it should not be used during breastfeeding.
💊 Overdose Management
There is no specific antidote for an overdose of this medicine. If an overdose is suspected, stop the medicine and seek immediate medical attention. Treatment should be supportive and symptomatic. Monitor vital signs and liver function. Dialysis is not expected to be helpful because this medicine is highly protein-bound.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
This medicine must only be taken exactly as prescribed by your doctor. Do not change the dose or stop the medicine without medical advice, because stopping suddenly may affect your treatment. Take the tablet at the same time each day to keep steady levels in your body. Swallow the tablet whole with a glass of water; do not crush or chew it unless your doctor or pharmacist says it is safe to do so. This medicine can be taken with or without food, but taking it with food may help if you get an upset stomach. Because this medicine may cause dizziness or tiredness, be careful when driving or operating machinery until you know how it affects you. Avoid handling this medicine if you are pregnant or may become pregnant, and keep it away from children. Tell your doctor about all other medicines, vitamins, and herbal products you are taking, especially blood thinners such as warfarin. Your doctor will monitor your liver function and blood counts regularly. If you develop yellowing of the eyes or skin, dark urine, severe tiredness, or shortness of breath, contact your doctor immediately. Store this medicine at room temperature, away from moisture and direct sunlight, and keep it in its original packaging.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, tiredness, and heart problems. Regular monitoring of liver and kidney function is important. The dose may need to be adjusted based on overall health and other medicines being taken.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated in pregnancy and should not be used by women who are pregnant or planning to become pregnant. Men taking this medicine should use reliable contraception during treatment and for a period after stopping, as it may harm a developing baby. Discuss family planning with your doctor.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anaesthesiologist that you are taking this medicine. It may affect blood clotting and liver function. Your doctor may advise you to stop the medicine temporarily before surgery. Do not stop without medical advice.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may increase the risk of bleeding or interact with other medicines used during dental work. Your dentist may need to take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause tiredness or dizziness. Avoid strenuous exercise if you feel unwell. Consult your doctor before starting any new exercise program. Low-impact activities are generally safe and beneficial.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause tiredness, dizziness, or hot flushes, which can affect your daily activities. You may need to adjust your work schedule or tasks if you feel unwell. Avoid driving or operating heavy machinery until you know how this medicine affects you. Discuss any work-related concerns with your doctor.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. Your doctor will decide when it is appropriate to stop based on your response to treatment, side effects, and overall health. If you experience severe side effects, contact your doctor immediately; they may adjust or stop the medicine.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to ongoing side effects such as breast tenderness, hot flushes, and fatigue. It can also cause liver problems, so regular liver function tests are necessary. Some patients may experience bone loss or heart problems over time. Your doctor will monitor you for these effects and adjust your treatment as needed. Do not stop the medicine without medical advice.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
These medicines lower testosterone levels and are often used together with this medicine.
Evidence: Well-establishedSurgical removal of the testicles lowers testosterone levels and may be used instead of or in addition to this medicine.
Evidence: Well-establishedUsed in advanced prostate cancer, often in combination with hormonal therapy.
Evidence: Well-establishedMay be used for localized prostate cancer or to relieve symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions known with this medicine. However, because it can affect blood counts, live vaccines should be avoided if your immune system is compromised. Discuss with your doctor before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container, tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after the expiry date
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a doctor's letter explaining that you need this medicine for a medical condition. Keep the medicine in your hand luggage to avoid loss or temperature extremes. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, continue taking your dose at the same time each day according to your home schedule, or ask your doctor for advice on adjusting the timing. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working soon after you begin taking it, but it may take several weeks to months to see the full benefits, such as a decrease in PSA levels. Your doctor will monitor your progress with regular tests.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset. However, avoid grapefruit juice as it can increase the levels of this medicine in your body.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose.
A: This medicine is often used for long periods, but it requires regular monitoring of liver function and other parameters. Your doctor will decide how long you should take it based on your condition and response to treatment.
A: No, this medicine is not for use in women, especially during pregnancy or breastfeeding. It can harm a developing baby. Women should also avoid handling this medicine.
🤔 Common Patient Concerns
🔄 Substitutes for tabi tablet
View AllAlternative brands with exact same active ingredient:
-
ablu 50mg tabletNeon Laboratories Ltd ₹185.20 85.1% CHEAPER
-
calured 50mg tabletRedmed Medical Services ₹350.00 71.8% CHEAPER
-
calbimide 50mg tabletEast West Pharma ₹350.63 71.7% CHEAPER
-
bicalon 50mg tabletCelon Laboratories Ltd ₹365.63 70.5% CHEAPER
-
cosalon 50mg tabletCelon Laboratories Ltd ₹365.63 70.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure prostate cancer completely.
Fact: This medicine helps control prostate cancer but does not cure it. It is used to slow cancer growth and manage symptoms. - Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for women, especially during pregnancy, and is contraindicated in severe liver disease. - Myth: You can stop taking this medicine once you feel better.
Fact: You should never stop this medicine without consulting your doctor. Stopping suddenly may worsen your condition. - Myth: This medicine has no serious side effects.
Fact: This medicine can cause serious liver problems and other side effects. Regular monitoring is essential.
🔄 Alternative Options
Generic Alternatives
- Bicalutamide 50 mg tablet
Brand Alternatives
- Calutide 50 mg tablet
- Bicalutamide 50 mg tablet (various manufacturers)