synasma syrup - Doxofylline (100mg) medicine

Doxovent 100mg Syrup: Complete Medicine Guide

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🏭 Sun Pharmaceutical Industries Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 21, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Fast or irregular heartbeat
  • Seizures
  • Severe allergic reactions (rash, swelling, difficulty breathing)
  • Severe nausea or vomiting
  • Blood in vomit or stool
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is synasma syrup used for?

This medicine is a bronchodilator used to treat asthma and COPD. It works by relaxing the muscles in the airways to make breathing easier. It is available as a 100mg syrup and is taken orally as prescribed by a doctor.

  • Generic Name: Doxofylline (100mg)
  • Manufacturer: Sun Pharmaceutical Industries Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 synasma syrup के बारे में (Hindi Summary)

उपयोग: यह दवा दमा और सीओपीडी जैसी सांस की बीमारियों में सांस लेने में आसानी के लिए दी जाती है। यह वायुमार्ग की मांसपेशियों को आराम देकर ब्रोन्कोडायलेशन करती है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट दर्द, सिरदर्द और बेचैनी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन तेज़ धड़कन, दौरे और एलर्जी हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। शराब का सेवन न करें। यदि आपको हृदय, यकृत, गुर्दे की बीमारी या पेप्टिक अल्सर है तो डॉक्टर को बताएं। चक्कर आने पर वाहन न चलाएं।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 synasma syrup Uses & Benefits

[{"condition":"Asthma","description":"Helps relieve bronchospasm and improves breathing in patients with asthma.","evidence":"Well-established"},{"condition":"Chronic Obstructive Pulmonary Disease (COPD)","description":"Used to manage symptoms of COPD, including wheezing and shortness of breath.","evidence":"Well-established"}]

Off-label uses: []

Primary treatment for: Asthma

Also treats: COPD

📋 Drug Information

Generic Name(s)Doxofylline (100mg)
Brand Namesynasma syrup
ManufacturerSun Pharmaceutical Industries Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassTheophylline & its derivatives
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Stay well hydrated throughout the day.
3
Avoid alcohol while taking this medicine.
4
Do not take more than the prescribed dose.
5
Consult your doctor if symptoms persist beyond 7 days.
6
Report any unusual heartbeat or seizures immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Wheezing
This medicine is commonly prescribed for this.
Likely Use
✅
Shortness of breath
This medicine helps relieve this symptom.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionDoxofylline is rapidly absorbed from the gastrointestinal tract after oral administration.
DistributionIt is widely distributed throughout the body, including the lungs and other tissues.
Protein BindingNot established from the available information.
MetabolismDoxofylline is metabolized in the liver.
Half-LifeThe elimination half-life of doxofylline is approximately 6-8 hours.
ExcretionIt is primarily excreted through the kidneys as metabolites.
BioavailabilityThe oral bioavailability of doxofylline is approximately 60-70%.
Onset of ActionThe onset of action is typically within 30 minutes to 1 hour after oral administration.
Peak Plasma TimePeak plasma concentrations are reached within 1-2 hours.
Duration of ActionThe duration of action is approximately 6-8 hours.

How It Works

Doxofylline works by inhibiting the enzyme phosphodiesterase, which leads to an increase in cyclic AMP (cAMP) levels in the smooth muscle cells of the airways. This results in relaxation of the bronchial smooth muscle and widening of the airways. Additionally, it may have mild anti-inflammatory effects and improve diaphragm contractility.

Mechanism Steps

1
Phosphodiesterase inhibition: Doxofylline inhibits the phosphodiesterase enzyme in airway smooth muscle cells.
2
Increased cAMP: This inhibition leads to higher levels of cyclic AMP within the cells.
3
Smooth muscle relaxation: Elevated cAMP causes relaxation of the bronchial smooth muscle, resulting in bronchodilation.

💡 How to Take synasma syrup

Strength: Syrup containing 100mg of doxofylline per 5ml.

1Shake the bottle well before use.
2Measure the dose using the provided measuring cup or spoon.
3Take the medicine with or without food, as directed by your doctor.
4Swallow the syrup directly; do not mix with other liquids unless instructed.
5Wash the measuring cup after each use.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100mg to 200mg two to three times daily, depending on the severity of the condition. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require a lower dose due to reduced renal and hepatic function. Dose must be individualized by a qualified clinician.
Renal ImpairmentDose adjustment may be required in patients with renal impairment. Consult a doctor.
Hepatic ImpairmentDose adjustment may be required in patients with hepatic impairment. Consult a doctor.
Maximum Daily DoseThe maximum recommended daily dose is 400mg, but this must be individualized by a clinician.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Caffeine
Limit
May increase stimulant effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of synasma syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. Consult doctor if persistent.
Vomiting (Common (5-10%))
Stay hydrated. Consult doctor if severe or persistent.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if severe.
Stomach pain (Common (5-10%))
Take with food. Consult doctor if persistent.
Restlessness (Common (5-10%))
Avoid caffeine. Consult doctor if bothersome.

🚨 Serious Side Effects

Fast or irregular heartbeat (Rare (<0.1%))
Seek immediate medical attention.
Seizures (Rare (<0.1%))
Seek immediate medical attention.
Severe allergic reactions (Rare (<0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.

⚠️ Rare Side Effects

Hypokalemia
Report to doctor if you experience muscle weakness or cramps.
Hyperglycemia
Monitor blood sugar if diabetic. Report to doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Erythromycin Major
Beta-blockers Moderate
Diuretics Moderate
Cimetidine Minor

🚨 Major Interactions

  • Ciprofloxacin
  • Erythromycin

⚡ Moderate Interactions

  • Beta-blockers
  • Diuretics

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine as it may increase the risk of side effects such as drowsiness and rapid heartbeat.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to doxofylline or other methylxanthines","Acute myocardial infarction","Severe cardiac arrhythmias","Severe liver disease","Peptic ulcer"]

⚠️ Warnings & Precautions

["Use with caution in patients with heart disease.","Use with caution in patients with liver disease.","Use with caution in patients with kidney disease.","Use with caution in the elderly.","Avoid in patients with peptic ulcer.","May cause dizziness; avoid driving or operating machinery until you know how it affects you."]

🤱 Lactation Safety

Not established from the available information. Consult your doctor before breastfeeding.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, rapid heartbeat, seizures, and cardiac arrest. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose. Avoid consuming alcohol while taking this medicine, as it may increase the risk of side effects. Inform your doctor if you have heart disease, liver disease, kidney disease, or peptic ulcer before starting this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking this medicine. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the effects of this medicine. Dose adjustment may be required.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning to become pregnant or are pregnant.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine, as it may interact with certain anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Avoid smoking and exposure to secondhand smoke.
🥗
Maintain a healthy weight.
😴
Practice breathing exercises.
💧
Get adequate rest.
🧘
Stay hydrated.

🏋️ Exercise Considerations

Avoid strenuous exercise if you experience shortness of breath or dizziness. Consult your doctor before starting any exercise program.

🥗 Diet Recommendations

Eat a balanced diet rich in fruits and vegetables.
Limit caffeine intake.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness. Avoid driving or operating heavy machinery until you know how it affects you.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. Your doctor will advise you on when and how to stop.

📅 Long-Term Use Effects

Long-term use of this medicine may require periodic monitoring of heart rate, blood pressure, and liver and kidney function. Consult your doctor for regular check-ups.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Inhaled bronchodilators

May be used as an alternative or in addition to oral therapy.

Evidence: Well-established
Inhaled corticosteroids

Used for long-term control of asthma.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Consult your doctor for routine vaccinations.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing schedule as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with asthma
Started this medicine as prescribed for asthma. Within a week, noticed significant improvement in breathing and reduced wheezing. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 60-year-old woman with COPD
Used this medicine regularly for COPD. Experienced mild nausea initially but it subsided after taking with meals. Breathing improved, allowing her to walk longer distances.
💡 Lesson: Taking the medicine with food can minimize side effects and improve adherence.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine typically starts working within 30 minutes to 1 hour after oral administration.

Q: Can I take this medicine with food?

A: Yes, taking it with food can help reduce stomach upset.

Q: Is it safe to take during pregnancy?

A: Consult your doctor before taking this medicine during pregnancy.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for synasma syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure asthma permanently.
    Fact: This medicine helps manage symptoms but does not cure asthma.
  • Myth: This medicine is safe to take without a prescription.
    Fact: This medicine is a prescription drug and should only be taken under medical supervision.

🔄 Alternative Options

Generic Alternatives

  • Doxofylline 100mg syrup

Brand Alternatives

  • Doxovent 100mg syrup

📊 Comparison with Similar Medicines

[{"medicine":"Doxofylline","class":"Methylxanthine","common_use":"Asthma, COPD","route":"Oral"},{"medicine":"Theophylline","class":"Methylxanthine","common_use":"Asthma, COPD","route":"Oral"}]

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