Swab PD 10mg/40mg Tablet: Complete Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in vomit or black, tarry stools
- Severe chest pain or difficulty breathing
- Irregular heartbeat or palpitations
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes (jaundice)
- Severe abdominal pain or persistent vomiting
- Uncontrollable muscle movements or tremors
If experiencing severe symptoms, call emergency services immediately.
What is swab pd 10mg/40mg tablet used for?
This medicine is a combination of Domperidone and Rabeprazole used to treat acid reflux, GERD, and functional dyspepsia. It works by reducing stomach acid and improving gastric emptying. It is taken orally once daily before a meal.
- Generic Name: Domperidone (10mg) + Rabeprazole (40mg)
- Manufacturer: Swabhumi Drug & Pharmaceuticals India Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 swab pd 10mg/40mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा डोम्पेरिडोन और रैबेप्राजोल का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, जीईआरडी, और अपच जैसी समस्याओं के इलाज के लिए किया जाता है। यह पेट में एसिड को कम करती है और पेट की गति को बढ़ाती है, जिससे जलन, गैस, और उल्टी जैसे लक्षणों में राहत मिलती है। इसे आमतौर पर दिन में एक बार नाश्ते से 30 मिनट पहले लिया जाता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में सिरदर्द, दस्त, मतली, पेट दर्द, और मुँह सूखना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन दिल की धड़कन अनियमित होना, एलर्जी, और मांसपेशियों में अनैच्छिक हरकतें हो सकती हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। इसे नाश्ते से 30 मिनट पहले पानी के साथ पूरा निगलें, चबाएं नहीं। शराब का सेवन न करें। यदि आपको हृदय, यकृत, या गुर्दे की बीमारी है तो डॉक्टर को बताएं। बिना डॉक्टर की सलाह के लंबे समय तक इसका उपयोग न करें।
💊 swab pd 10mg/40mg tablet Uses & Benefits
[{"condition":"Gastroesophageal reflux disease (GERD)","description":"This medicine helps reduce acid reflux and heartburn by decreasing stomach acid production and improving gastric emptying.","evidence":"Well-established"},{"condition":"Functional dyspepsia","description":"It relieves symptoms like bloating, early fullness, and upper abdominal discomfort by enhancing gastric motility and reducing acid.","evidence":"Moderate"},{"condition":"Gastroparesis","description":"Domperidone component helps improve stomach emptying in diabetic or idiopathic gastroparesis, while Rabeprazole reduces associated acid symptoms.","evidence":"Limited"},{"condition":"Nausea and vomiting associated with acid peptic disorders","description":"Domperidone provides antiemetic effect, and Rabeprazole treats underlying acid-related issues.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Refractory GERD not responding to PPI alone","description":"Sometimes prescribed off-label when a PPI alone fails to control symptoms, based on the rationale that adding a prokinetic improves outcomes.","evidence":"Limited"}]
Primary treatment for: Gastroesophageal reflux disease (GERD)
Also treats: Functional dyspepsia, Gastroparesis, Nausea and vomiting associated with acid peptic disorders
📋 Drug Information
| Generic Name(s) | Domperidone (10mg) + Rabeprazole (40mg) |
| Brand Name | swab pd 10mg/40mg tablet |
| Manufacturer | Swabhumi Drug & Pharmaceuticals India Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary mechanisms. Rabeprazole is a proton pump inhibitor that irreversibly inhibits the H+/K+-ATPase enzyme in gastric parietal cells, blocking the final step of acid secretion. Domperidone is a peripheral dopamine D2 receptor antagonist that enhances gastrointestinal motility and gastric emptying by blocking dopamine receptors in the gut, and it also has antiemetic effects via the chemoreceptor trigger zone. Together, they reduce acid exposure and improve gastric motility.
Mechanism Steps
💡 How to Take swab pd 10mg/40mg tablet
Strength: Immediate-release tablet containing Domperidone 10 mg and Rabeprazole 40 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Domperidone 10 mg + Rabeprazole 40 mg) taken orally once daily, preferably 30 minutes before breakfast. However, the dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to therapy. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially cardiac effects and extrapyramidal symptoms. Use with caution and consider lower doses. Dose must be individualized by a qualified clinician. |
| Renal Impairment | Dose adjustment may be required in patients with renal impairment. Domperidone is contraindicated in moderate to severe renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with mild to moderate hepatic impairment. Contraindicated in severe hepatic impairment. Dose adjustment may be necessary. Consult a doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is one tablet (Domperidone 10 mg + Rabeprazole 40 mg) per day. Do not exceed this dose without medical advice. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of swab pd 10mg/40mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Warfarin | Major | |
| Methotrexate | Major | |
| Antacids | Moderate | |
| Atazanavir | Moderate | |
| Digoxin | Moderate | |
| Paracetamol | Minor | |
| Amoxicillin | Minor |
🚨 Major Interactions
- Ketoconazole, itraconazole, clarithromycin
- Warfarin
- Methotrexate
⚡ Moderate Interactions
- Antacids
- Atazanavir, nelfinavir
- Digoxin
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase stomach acid production, worsening the condition being treated, and may increase the risk of central nervous system side effects such as drowsiness and dizziness. It can also exacerbate gastrointestinal irritation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to Domperidone, Rabeprazole, or any component of the formulation","Gastrointestinal bleeding, mechanical obstruction, or perforation","Prolactin-releasing pituitary tumor (prolactinoma)","Severe hepatic impairment","Concomitant use with strong CYP3A4 inhibitors like ketoconazole, clarithromycin","Known QT prolongation or family history of long QT syndrome","Moderate to severe renal impairment (for Domperidone)"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disease or risk factors for QT prolongation.","Avoid in patients with electrolyte disturbances (hypokalemia, hypomagnesemia).","May increase the risk of bone fractures with long-term use.","Can mask symptoms of stomach cancer; rule out malignancy before starting.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Do not use for longer than 12 weeks without medical review.","Use with caution in elderly patients due to increased risk of side effects."]
🤱 Lactation Safety
Domperidone is excreted in breast milk and may cause side effects in the infant. Rabeprazole may also pass into breast milk. This medicine is not recommended during breastfeeding unless the potential benefit outweighs the risk. Consult your doctor.
💊 Overdose Management
Overdose may cause severe drowsiness, extrapyramidal symptoms, and cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1 hour of ingestion. Monitor ECG and vital signs.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not crush, chew, or break the tablet; swallow it whole with water. Take it at least 30 minutes before a meal, preferably breakfast. Avoid alcohol while taking this medicine as it may increase stomach acid and worsen your condition. Do not take antacids or other acid-reducing medicines without consulting your doctor, as they may interact. If you have a history of heart problems, liver disease, or kidney disease, inform your doctor before starting this medicine. Do not use this medicine for longer than recommended without medical supervision. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of side effects such as cardiac arrhythmias, extrapyramidal symptoms, and bone fractures. Use with caution and consider lower doses. Regular monitoring of renal and hepatic function is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It should only be used if clearly needed. Discuss alternative treatments that are safer during pregnancy.
🏥 Post-Surgery Considerations
After surgery, use this medicine only if prescribed by your surgeon. It may affect gastric motility and acid secretion, which could impact post-operative recovery. Inform your surgeon about all medications you are taking.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, especially if you are scheduled for oral surgery. It may increase the risk of bleeding if you are also on anticoagulants. No specific precautions are otherwise needed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Moderate exercise is generally safe, but avoid vigorous exercise immediately after meals as it may worsen reflux. Listen to your body and stop if you feel dizzy or experience palpitations.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take regular breaks and avoid heavy lifting after meals.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms resolve, your doctor may advise tapering or stopping. Abrupt discontinuation may cause rebound acid hypersecretion.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of bone fractures, low magnesium levels, vitamin B12 deficiency, and gastrointestinal infections. Domperidone may cause tardive dyskinesia and cardiac arrhythmias with prolonged use. Regular monitoring and periodic review by a doctor are recommended. Do not use for longer than 12 weeks without medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Dietary changes, weight loss, and avoiding trigger foods can significantly reduce GERD symptoms.
Evidence: Well-establishedAlternative acid-suppressing medications may be used if this combination is not suitable.
Evidence: Well-establishedConsidered for severe GERD not responding to medication.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, long-term use of Rabeprazole may theoretically reduce the efficacy of oral vaccines due to altered gastric pH. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking it once daily before your first meal of the day. Check local customs regulations regarding prescription medicines. Always carry enough supply for the duration of your trip.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Rabeprazole starts reducing acid within 1 hour, and Domperidone improves motility within 30-60 minutes. Symptom relief may take a few days of regular use.
A: It can interact with several drugs, including ketoconazole, warfarin, and methotrexate. Always inform your doctor about all medicines you are taking.
A: It should only be used if clearly needed and prescribed by a doctor. Consult your doctor for risk-benefit assessment.
A: If you remember within 12 hours, take it as soon as possible. If more than 12 hours have passed, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for swab pd 10mg/40mg tablet
View AllAlternative brands with exact same active ingredient:
-
cociarab d 10mg/40mg tabletScocia Labs ₹71.00 36.5% COSTLIER
-
ulcigard forte 10 mg/40 mg tablet srMeridian Medicare Ltd ₹84.38 62.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken anytime without regard to meals.
Fact: It should be taken at least 30 minutes before a meal for best effect. - Myth: This medicine is safe to take indefinitely.
Fact: Long-term use should be monitored by a doctor due to potential side effects. - Myth: This medicine can cure all types of stomach pain.
Fact: It is specifically for acid-related and motility disorders, not all stomach pains.
🔄 Alternative Options
Generic Alternatives
- Domperidone + Rabeprazole combination generics available
Brand Alternatives
- Swab PD 10mg/40mg tablet