Sparcid DS 400mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Palpitations, fainting, or irregular heartbeat
- Sudden joint or tendon pain, swelling, or difficulty moving a limb
- Numbness, tingling, burning, or weakness in hands or feet
- Severe skin rash, blisters, peeling skin, or sores in the mouth or eyes
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain
- Signs of severe low blood sugar such as confusion, sweating, or shakiness
- Swelling of the face, lips, tongue, or throat with difficulty breathing
- Seizure or sudden confusion or hallucinations
If experiencing severe symptoms, call emergency services immediately.
What is Suplo 400mg Tablet used for?
This medicine contains Sparfloxacin 400 mg, a fluoroquinolone antibiotic used for certain bacterial infections of the lungs, skin, and urinary tract. It is taken once daily by mouth, but it can cause heart rhythm changes, tendon problems, and sun sensitivity, so it is usually reserved for situations where safer antibiotics are not suitable.
- Generic Name: Sparfloxacin (400mg)
- Manufacturer: Mapra Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Suplo 400mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा स्पारफ्लोक्सासिन 400 मिलीग्राम की एक टैबलेट है, जो फ्लोरोक्विनोलोन वर्ग की एंटीबायोटिक है। इसका उपयोग कुछ बैक्टीरियल संक्रमणों जैसे श्वसन तंत्र के संक्रमण, त्वचा के संक्रमण और मूत्र मार्ग के संक्रमण के इलाज के लिए किया जाता है, लेकिन यह केवल तभी दी जाती है जब डॉक्टर को लगता है कि अन्य सुरक्षित एंटीबायोटिक्स काम नहीं करेंगी। यह दवा दिल की धड़कन को प्रभावित कर सकती है, धूप के प्रति त्वचा की संवेदनशीलता बढ़ा सकती है और ब्लड शुगर को बदल सकती है, इसलिए इसे डॉक्टर की सलाह के बिना नहीं लेना चाहिए।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मतली, दस्त, पेट में दर्द, सिरदर्द, चक्कर आना और धूप के प्रति त्वचा की संवेदनशीलता शामिल हैं। कुछ लोगों में स्वाद में बदलाव, मुँह सूखना या नींद की समस्या हो सकती है। दुर्लभ लेकिन गंभीर दुष्प्रभावों में दिल की धड़कन में अनियमितता, बेहोशी, टेंडन का दर्द या टूटना, हाथ-पैरों में झनझनाहट, गंभीर त्वचा प्रतिक्रियाएँ, लीवर की समस्या और ब्लड शुगर में गंभीर गिरावट शामिल हैं। अगर आपको सीने में धड़कन महसूस हो, बेहोशी आए, जोड़ों में अचानक दर्द हो, त्वचा पर चकत्ते पड़ें या आँखें-त्वचा पीली दिखें, तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें और पूरा कोर्स पूरा करें, भले ही आपको कुछ दिनों में आराम महसूस होने लगे। टैबलेट को एक गिलास पानी के साथ निगलें और दिन भर पर्याप्त पानी पिएँ। इस दवा के सेवन के दौरान तेज धूप से बचें, सनस्क्रीन लगाएँ और पूरी आस्तीन के कपड़े पहनें। एंटासिड, आयरन, जिंक या सुक्रालफेट इस दवा से 2 घंटे पहले या बाद में न लें, क्योंकि इससे दवा का असर कम हो सकता है। अगर आपको दिल की बीमारी, डायबिटीज, किडनी या लीवर की समस्या है, तो डॉक्टर को जरूर बताएं। इस दवा के साथ शराब न पिएँ। चक्कर आने पर गाड़ी न चलाएँ। धड़कन बढ़ने, बेहोशी, टेंडन में दर्द या त्वचा पर गंभीर प्रतिक्रिया होने पर तुरंत डॉक्टर से संपर्क करें।
💊 Suplo 400mg Tablet Uses & Benefits
[{"condition":"Acute exacerbation of chronic bronchitis","description":"This medicine may be used to treat bacterial flare-ups of chronic bronchitis when the doctor identifies susceptible bacteria and considers other antibiotics unsuitable.","evidence":"Established for susceptible bacterial infections"},{"condition":"Community-acquired pneumonia","description":"This medicine can be prescribed for certain cases of community-acquired pneumonia caused by susceptible bacteria, but it is not a first-line choice because of safety concerns.","evidence":"Established for susceptible bacterial infections"},{"condition":"Skin and soft tissue infections","description":"This medicine may be used for some bacterial skin and soft tissue infections when the organism is susceptible and safer options cannot be used.","evidence":"Limited to susceptible organisms"},{"condition":"Urinary tract infections","description":"This medicine has been used for certain urinary tract infections caused by susceptible bacteria, but safer fluoroquinolones are generally preferred.","evidence":"Limited"}]
Off-label uses: [{"condition":"Mycobacterial infections","description":"Sparfloxacin has been studied in some atypical mycobacterial infections, but this is not a standard approved use and must only be considered by a specialist.","evidence":"Limited"},{"condition":"Leprosy","description":"Some fluoroquinolones have been explored in leprosy regimens, but Sparfloxacin is not a standard recommended agent for this purpose.","evidence":"Limited"}]
Primary treatment for: Bacterial respiratory tract infections
Also treats: Skin and soft tissue infections, Urinary tract infections
📋 Drug Information
| Generic Name(s) | Sparfloxacin (400mg) |
| Brand Name | Suplo 400mg Tablet |
| Manufacturer | Mapra Laboratories Pvt Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C in a dry place, away from direct sunlight and moisture. Keep it in the original container with the lid tightly closed. |
| Shelf Life | The shelf life is typically 24 months from the date of manufacture, but you should always check the expiry date printed on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by inhibiting two bacterial enzymes, DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication, repair, and segregation. By blocking these enzymes, Sparfloxacin prevents bacteria from copying and maintaining their genetic material, which stops bacterial growth and leads to bacterial cell death. This action is selective for bacterial enzymes, which is why it can treat infections without directly harming human cells, although it can still cause side effects in the body.
Mechanism Steps
💡 How to Take Suplo 400mg Tablet
Strength: Sparfloxacin 400 mg immediate-release tablet for oral use.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 400 mg taken orally once daily on the first day, followed by 200 mg once daily on subsequent days, but the exact dose and duration depend on the type and severity of the infection, kidney and liver function, and other medicines being taken. Some clinicians may prescribe 400 mg once daily for certain infections. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Older adults may be more sensitive to the side effects of this medicine, especially heart rhythm changes, tendon problems, and blood sugar disturbances. Kidney function should be checked before prescribing, and the dose may need to be adjusted by a qualified clinician. |
| Renal Impairment | Sparfloxacin is eliminated partly through the kidneys. In patients with severe kidney impairment, dose adjustment may be necessary. A qualified clinician should assess kidney function and decide the appropriate dose. |
| Hepatic Impairment | Sparfloxacin undergoes limited liver metabolism. In patients with severe liver impairment, caution is advised, and dose adjustment may be needed based on clinical judgment. |
| Maximum Daily Dose | The maximum recommended daily dose is 400 mg, but the exact maximum for an individual patient must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Suplo 400mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Amiodarone | Major | |
| Antacids | Major | |
| Iron supplements | Major | |
| Insulin | Major | |
| Warfarin | Major | |
| Caffeine | Moderate | |
| NSAIDs | Moderate | |
| Theophylline | Moderate | |
| Corticosteroids | Moderate | |
| Probenecid | Minor |
🚨 Major Interactions
- Amiodarone, sotalol, quinidine, procainamide, and other QT-prolonging drugs
- Antacids, sucralfate, iron, zinc, and multivitamins containing these minerals
- Insulin and oral antidiabetic drugs
- Warfarin and other anticoagulants
⚡ Moderate Interactions
- Caffeine
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Theophylline
- Corticosteroids
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can increase the risk of dizziness, drowsiness, and liver-related side effects. Alcohol may also worsen heart rhythm disturbances and make it harder to judge whether symptoms such as palpitations or fainting are due to the medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy or hypersensitivity to Sparfloxacin or any other fluoroquinolone antibiotic","Known QT interval prolongation or a history of serious heart rhythm disturbances","Uncorrected low blood potassium or low blood magnesium","Pregnancy and breastfeeding","Children and adolescents under 18 years of age","Severe liver impairment","History of tendon disorders related to fluoroquinolone use"]
⚠️ Warnings & Precautions
["This medicine can cause serious heart rhythm problems. Tell your doctor if you have heart disease, palpitations, or fainting spells.","Avoid strong sunlight and tanning beds because this medicine can cause severe photosensitivity reactions.","This medicine can cause tendon pain and rupture, especially in older adults, people taking corticosteroids, and those with kidney disease. Stop the medicine and seek medical help if tendon pain occurs.","This medicine can cause nerve damage with numbness, tingling, or weakness. Report these symptoms to your doctor promptly.","This medicine can cause low or high blood sugar. Monitor your blood glucose closely if you have diabetes.","This medicine may lower the seizure threshold. Use with caution if you have a seizure disorder.","Do not take antacids, iron, zinc, or sucralfate within 2 hours of this medicine.","Complete the full course as prescribed to prevent antibiotic resistance."]
🤱 Lactation Safety
Sparfloxacin may pass into breast milk and is not recommended during breastfeeding because of potential effects on the infant's joints and cartilage. If this medicine is essential, breastfeeding may need to be interrupted, and you should discuss this with your doctor.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, dizziness, heart rhythm disturbances, and seizures. If you suspect an overdose, seek emergency medical care immediately. Treatment is supportive and may include monitoring of heart rhythm, electrolytes, and vital signs. There is no specific antidote, and activated charcoal may be considered if the overdose is recent and the patient is stable.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember if less than half of the dosing interval has passed. If more than half of the dosing interval has passed, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor and complete the full course even if you start feeling better after a few days. Swallow the tablet with a full glass of water and maintain good hydration throughout the day. Avoid strong sunlight and do not use tanning beds or sunlamps while taking this medicine, because it can make your skin very sensitive to light. Use a broad-spectrum sunscreen and protective clothing when you go outdoors. Do not take antacids, sucralfate, iron supplements, zinc supplements, or multivitamins containing these minerals within two hours before or after this medicine, as they can reduce its absorption. Inform your doctor if you have heart problems, diabetes, kidney or liver disease, or if you take medicines for blood sugar, blood thinning, or heart rhythm. Avoid alcohol during treatment. Do not drive or operate heavy machinery if you feel dizzy. Tell your doctor right away if you develop palpitations, fainting, tendon pain, numbness or tingling, or unusual skin reactions.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Older adults are at higher risk of heart rhythm disturbances, tendon rupture, blood sugar changes, and kidney problems while taking this medicine. Kidney function should be checked before prescribing, and the dose may need adjustment. Close monitoring is advised.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended if you are trying to conceive, pregnant, or breastfeeding because of potential effects on the developing baby's joints and cartilage. Discuss safer antibiotic options with your doctor before planning pregnancy.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon and anesthesiologist that you are taking this medicine, because it can affect heart rhythm and interact with other medicines used during surgery. Your doctor may advise stopping it before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It can interact with some medicines used in dentistry and may increase the risk of bleeding if you are also taking blood thinners. Your dentist may coordinate with your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine because of the risk of tendon pain and rupture. If you feel any joint or tendon pain, stop exercising and seek medical advice. Light activity is usually fine if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause dizziness, tiredness, and sensitivity to sunlight, which may affect your ability to drive or operate machinery. Avoid driving until you know how the medicine affects you. If your work involves heavy lifting or strenuous activity, discuss with your doctor because of the risk of tendon problems. Take precautions against sun exposure if you work outdoors.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. However, stop immediately and seek medical help if you develop palpitations, fainting, tendon pain, numbness or tingling, severe skin rash, or signs of an allergic reaction. Your doctor may switch you to a different antibiotic if needed.
📅 Long-Term Use Effects
Long-term use of this medicine is not usually recommended because of the risk of heart rhythm problems, tendon damage, nerve damage, and antibiotic resistance. If prolonged therapy is necessary, your doctor will monitor your heart rhythm, blood sugar, kidney and liver function, and tendon health. Report any new symptoms such as palpitations, numbness, or joint pain promptly.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Safer antibiotics such as amoxicillin, azithromycin, or levofloxacin may be used depending on the infection and susceptibility.
Evidence: Well-establishedRest, fluids, and fever control can help while the infection resolves.
Evidence: Well-establishedPneumococcal and influenza vaccines can help prevent respiratory infections that might require antibiotics.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no specific vaccine interactions reported with this medicine. However, if you are due for any vaccine, inform your doctor, as antibiotics may be a sign of an active infection that could affect vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in the original container with the lid tightly closed
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in the bathroom cabinet
✅ DO
Check the expiry date before use
❌ DON'T
Do not use expired tablets
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription and a doctor's letter explaining why you need this antibiotic, especially for international travel. Store it at room temperature and keep it away from direct sunlight and moisture during travel. If you are crossing time zones, ask your doctor how to adjust the once-daily dose. Do not pack it in checked luggage; keep it in your hand baggage. Check the customs rules of your destination for prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours, but you must complete the full course as prescribed. If symptoms do not improve within 3 to 5 days, contact your doctor.
A: Yes, you can take it with food, which may reduce stomach upset. However, avoid taking it with dairy products, antacids, iron, or zinc supplements within 2 hours.
A: Avoid driving or operating machinery until the dizziness passes. If it is severe or persistent, contact your doctor.
A: No, you must complete the full prescribed course to prevent the infection from returning and to reduce antibiotic resistance.
A: This medicine is not recommended during pregnancy. Inform your doctor immediately if you are pregnant or planning pregnancy.
🤔 Common Patient Concerns
🔄 Substitutes for Suplo 400mg Tablet
View AllAlternative brands with exact same active ingredient:
-
Sparnij 400mg TabletSunij Pharma Pvt Ltd ₹28.18 11.1% CHEAPER
-
Sparflin 400mg TabletLupin Ltd ₹32.81 3.5% COSTLIER
-
sparcid ds 400mg tabletPatson Laboratories Pvt Ltd ₹78.00 146% COSTLIER
-
Sparkle 400mg TabletAlkem Laboratories Ltd ₹92.32 191.1% COSTLIER
-
Torospar 400mg TabletTorrent Pharmaceuticals Ltd ₹102.60 223.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Sparfloxacin can be taken for any fever or cold.
Fact: This medicine only works against certain bacteria and should not be used for viral infections like the common cold. - Myth: Sparfloxacin is a safe first-choice antibiotic.
Fact: Because of heart rhythm, tendon, and blood sugar risks, it is usually reserved for specific situations and is not a first-line antibiotic. - Myth: You can stop Sparfloxacin as soon as you feel better.
Fact: You must complete the full prescribed course to prevent the infection from returning and to reduce antibiotic resistance. - Myth: Sparfloxacin does not interact with other medicines.
Fact: It interacts with antacids, iron, zinc, blood thinners, diabetes medicines, and heart rhythm medicines, so always inform your doctor about all medicines you take.
🔄 Alternative Options
Generic Alternatives
- Sparfloxacin 400 mg tablet
Brand Alternatives
- Sparcid DS 400 mg tablet