Sulmox 500mg/250mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe or persistent diarrhoea, abdominal cramps, or fever.
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- Decreased urine output, swelling in the legs or feet, or unusual fatigue.
- Severe skin rash with blisters or peeling.
- Unusual bleeding or bruising.
- Seizures or severe dizziness.
If experiencing severe symptoms, call emergency services immediately.
What is sulmox 500mg/250mg tablet used for?
This medicine is a combination antibiotic containing amoxycillin and sulbactam. It is used to treat a variety of bacterial infections, including respiratory, urinary tract, skin, and dental infections. It works by killing bacteria and blocking the enzymes that make bacteria resistant to amoxycillin. It is a prescription medicine and should be taken exactly as directed by your doctor.
- Generic Name: Amoxycillin (500mg) + Sulbactam (250mg)
- Manufacturer: Lemford Biotech Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sulmox 500mg/250mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक है जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है। इसमें अमोक्सिसिलिन और सल्बैक्टम दो सक्रिय तत्व होते हैं। यह श्वसन तंत्र, मूत्र मार्ग, त्वचा और दांतों के संक्रमण के इलाज में प्रभावी है। यह बैक्टीरिया को मारकर और उनके प्रतिरोध को कम करके काम करती है। इस दवा को डॉक्टर के निर्देशानुसार ही लें और कोर्स पूरा करें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द और त्वचा पर चकत्ते शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें गंभीर एलर्जी प्रतिक्रिया, लीवर या किडनी की समस्या, और गंभीर दस्त शामिल हो सकते हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों और एलर्जी के बारे में बताएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। शराब का सेवन न करें क्योंकि इससे दुष्प्रभाव बढ़ सकते हैं। दवा का कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। दवा को बच्चों की पहुंच से दूर रखें।
💊 sulmox 500mg/250mg tablet Uses & Benefits
[{"condition":"Respiratory tract infections","description":"Used to treat bacterial infections of the upper and lower respiratory tract, such as sinusitis, pharyngitis, tonsillitis, and pneumonia.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against bacterial infections of the urinary tract, including cystitis and pyelonephritis.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for bacterial skin infections such as cellulitis, abscesses, and wound infections.","evidence":"Well-established"},{"condition":"Dental infections","description":"Prescribed for dental abscesses and other odontogenic infections.","evidence":"Well-established"},{"condition":"Gonorrhoea","description":"May be used in combination therapy for treating gonorrhoea, a sexually transmitted infection.","evidence":"Established"}]
Off-label uses: [{"condition":"Helicobacter pylori eradication","description":"Sometimes used as part of a combination regimen to eradicate H. pylori, the bacterium that causes stomach ulcers.","evidence":"Limited"},{"condition":"Lyme disease","description":"May be used off-label for early Lyme disease in some cases, though other antibiotics are more commonly used.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Skin and soft tissue infections, Dental infections, Gonorrhoea
📋 Drug Information
| Generic Name(s) | Amoxycillin (500mg) + Sulbactam (250mg) |
| Brand Name | sulmox 500mg/250mg tablet |
| Manufacturer | Lemford Biotech Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and heat. Keep the medicine in its original container, tightly closed. Do not refrigerate unless specified on the label. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture, but refer to the expiry date printed on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by combining two active ingredients. Amoxycillin is a penicillin antibiotic that kills bacteria by interfering with the formation of their cell walls. It binds to specific proteins called penicillin-binding proteins inside the bacterial cell wall, preventing the bacteria from building a strong cell wall. This causes the bacteria to burst and die. However, some bacteria produce enzymes called beta-lactamases that can break down amoxycillin and make it ineffective. Sulbactam is a beta-lactamase inhibitor that binds to these enzymes and blocks their action, protecting amoxycillin from being destroyed. This allows amoxycillin to kill bacteria that would otherwise be resistant. Together, they provide a broader spectrum of activity against many common bacteria.
Mechanism Steps
💡 How to Take sulmox 500mg/250mg tablet
Strength: This medicine is available as an immediate-release tablet containing 500mg of amoxycillin and 250mg of sulbactam.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet (500mg amoxycillin + 250mg sulbactam) taken orally every 8 to 12 hours, depending on the type and severity of the infection. For uncomplicated infections, it may be taken every 12 hours, while more severe infections may require dosing every 8 hours. The duration of treatment varies from 5 to 14 days, as determined by your doctor. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary based on renal function. Your doctor will determine the appropriate dose. Elderly patients should be monitored for signs of toxicity. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For patients with a creatinine clearance (CrCl) of 10-30 mL/min, the dose may be reduced or the dosing interval extended. For CrCl less than 10 mL/min, the dose should be further reduced, and the medicine should be used with caution. Consult your doctor for specific dosing recommendations based on your kidney function. |
| Hepatic Impairment | No specific dose adjustment is provided for hepatic impairment in the available information. However, this medicine should be used with caution in patients with liver disease, and liver function should be monitored. Consult your doctor for guidance. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 1500mg of amoxycillin and 750mg of sulbactam (i.e., three tablets per day) in divided doses. However, higher doses may be used in severe infections under medical supervision. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sulmox 500mg/250mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Allopurinol | Moderate | |
| Oral contraceptives | Moderate | |
| Probenecid | Moderate | |
| Tetracyclines | Moderate | |
| Antacids | Minor | |
| Laxatives | Minor |
🚨 Major Interactions
- Warfarin
- Methotrexate
- Allopurinol
⚡ Moderate Interactions
- Oral contraceptives
- Probenecid
- Tetracyclines
🍷 Alcohol Interaction
It is advisable to avoid alcohol while taking this medicine, as it may increase the risk of stomach upset, nausea, and vomiting. Alcohol does not directly interact with the antibiotic, but it can worsen the side effects and may hinder your recovery from the infection.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to amoxycillin, sulbactam, or any other penicillin or beta-lactam antibiotic","History of severe allergic reaction (e.g., anaphylaxis) to any beta-lactam antibiotic","Infectious mononucleosis (may increase risk of rash)","Severe renal impairment (dose adjustment required)"]
⚠️ Warnings & Precautions
["Before starting this medicine, inform your doctor about all your medical conditions, especially kidney or liver disease, asthma, or allergies.","This medicine may cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use this medicine to treat viral infections like the common cold or flu, as it is ineffective.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi. Monitor for superinfections.","If you develop a rash, stop the medicine and consult your doctor immediately, as it may be a sign of allergy.","Use with caution in patients with a history of gastrointestinal disease, especially colitis.","This medicine may interfere with certain laboratory tests, such as urine glucose tests. Inform your doctor if you are undergoing any tests."]
🤱 Lactation Safety
Amoxycillin and sulbactam are excreted in breast milk in small amounts. This medicine is generally considered safe during breastfeeding, but it may cause diarrhoea or thrush in the nursing infant. Monitor your baby for any signs of infection or diarrhoea, and consult your doctor if you have concerns.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, diarrhoea, and abdominal pain. In severe cases, it may lead to electrolyte imbalance and kidney problems. If you suspect an overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Haemodialysis can remove amoxycillin and sulbactam from the blood in cases of severe overdose, especially in patients with renal failure.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Before taking this medicine, tell your doctor if you are allergic to penicillin, cephalosporins, or any other antibiotics. Also, inform your doctor if you have kidney or liver disease, asthma, or a history of allergies. This medicine may reduce the effectiveness of oral contraceptives, so use additional contraception while taking it. Avoid alcohol while taking this medicine as it may worsen side effects like nausea and stomach upset. Do not share this medicine with others, even if they have similar symptoms. Complete the full course as prescribed, even if you feel better after a few days. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary. They are also at higher risk of side effects such as diarrhoea and allergic reactions. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe during pregnancy, but the decision to use it should be based on the potential benefits and risks. Inform your doctor if you become pregnant while taking this medicine.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent or treat surgical site infections. It is important to take it exactly as directed and to inform your surgeon if you experience any side effects. It does not interfere with the healing process but helps prevent infection.
🦷 Dental Procedures
This medicine is often prescribed before or after dental procedures to prevent or treat dental infections. Inform your dentist if you are taking this medicine, as it may interact with other medications used during dental procedures. It is important to complete the course as prescribed.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you can continue with light to moderate exercise if you feel up to it. However, if you experience dizziness, fatigue, or muscle pain, avoid strenuous activities and take rest. Listen to your body and do not overexert yourself.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can continue their normal daily activities, but it is important to take the medicine regularly and complete the course.
🛑 When to Stop This Medicine
You should stop taking this medicine only after completing the full course prescribed by your doctor. If you experience severe side effects such as a severe allergic reaction, stop the medicine and seek immediate medical attention. Do not stop the medicine early just because you feel better, as this can lead to a relapse of the infection and antibiotic resistance.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to antibiotic resistance and may increase the risk of superinfections, such as oral thrush or Clostridium difficile-associated diarrhoea. It is not intended for long-term use unless prescribed for a specific chronic infection. Regular monitoring of kidney and liver function may be required if used for extended periods. Always consult your doctor before using this medicine for more than the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the type of infection and bacterial sensitivity, other antibiotics such as amoxycillin-clavulanate or cephalosporins may be used.
Evidence: Well-establishedFor viral infections, rest, fluids, and over-the-counter pain relievers may be used, as antibiotics are not effective.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled to receive a live vaccine, inform your doctor, as antibiotics may affect the immune response to certain vaccines. In general, antibiotics do not interfere with most vaccines.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When travelling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep it in your hand luggage to avoid loss or exposure to extreme temperatures. Store it at room temperature, away from direct sunlight and moisture. If you are crossing time zones, adjust your dosing schedule gradually, but consult your doctor for specific advice. Check the customs regulations of your destination country regarding prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: Take the missed dose as soon as you remember, unless it is almost time for your next dose. Do not double the dose.
A: It is generally considered safe, but you should consult your doctor before taking any medicine during pregnancy.
A: It is best to avoid alcohol as it may worsen side effects and slow down your recovery.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed, even if you feel better, to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe to take without a prescription.
Fact: This medicine is a prescription drug and should only be taken under the guidance of a qualified doctor. - Myth: Taking this medicine with alcohol is safe.
Fact: Alcohol can worsen side effects like nausea and stomach upset, and it may hinder your recovery. It is best to avoid alcohol while taking this medicine.
🔄 Alternative Options
Generic Alternatives
- Amoxycillin + Sulbactam generic tablets
Brand Alternatives
- Sulmox 500mg/250mg tablet