sudin sera plus  tablet - Bromhexine (4mg) + Chlorpheniramine Maleate (2mg) medicine

Anticold Linctus: Complete Medicine Guide

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🏭 Group Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for symptomatic relief of cough and cold.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swallowing
  • Swelling of face, lips, or throat
  • Irregular heartbeat or palpitations
  • Seizures
  • Severe drowsiness or confusion
  • Blood in cough or vomit
  • Yellowing of skin or eyes

If experiencing severe symptoms, call emergency services immediately.

What is sudin sera plus tablet used for?

This medicine is a combination of bromhexine and chlorpheniramine maleate used for temporary relief of cough and cold symptoms. It works by loosening mucus and blocking histamine. It may cause drowsiness, so avoid driving. Do not use for more than 7 days without consulting a doctor.

  • Generic Name: Bromhexine (4mg) + Chlorpheniramine Maleate (2mg)
  • Manufacturer: Group Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 sudin sera plus tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन और क्लोरफेनिरामाइन मेलिएट का संयोजन है, जिसका उपयोग खांसी और जुकाम के लक्षणों जैसे बलगम, छींक, नाक बहना और आंखों में पानी आना के अस्थायी राहत के लिए किया जाता है। यह बलगम को पतला करके बाहर निकालने में मदद करती है और एलर्जी के लक्षणों को कम करती है। यह दवा नींद ला सकती है, इसलिए वाहन चलाने से बचें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, जी मिचलाना और पेट खराब होना शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में एलर्जी की प्रतिक्रिया, दिल की धड़कन अनियमित होना, दौरे पड़ना आदि शामिल हैं। यदि कोई गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं के बारे में बताएं, खासकर यदि आपको अस्थमा, ग्लूकोमा, प्रोस्टेट की समस्या, हृदय रोग या उच्च रक्तचाप है। यह दवा नींद ला सकती है, इसलिए वाहन चलाने या मशीन चलाने से बचें। शराब का सेवन न करें। 7 दिनों से अधिक इसका उपयोग न करें। बच्चों और बुजुर्गों में सावधानी बरतें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 sudin sera plus tablet Uses & Benefits

[{"condition":"Productive cough","description":"Helps loosen mucus and makes it easier to cough out.","evidence":"Well-established for bromhexine"},{"condition":"Common cold","description":"Relieves sneezing, runny nose, and watery eyes due to allergic rhinitis or common cold.","evidence":"Well-established for chlorpheniramine"},{"condition":"Allergic rhinitis","description":"Reduces allergy symptoms such as sneezing and itching.","evidence":"Well-established for chlorpheniramine"}]

Off-label uses: []

Primary treatment for: Cough and cold

Also treats: Allergic rhinitis, Productive cough

📋 Drug Information

Generic Name(s)Bromhexine (4mg) + Chlorpheniramine Maleate (2mg)
Brand Namesudin sera plus tablet
ManufacturerGroup Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from light and moisture. Keep the bottle tightly closed.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food or milk to reduce stomach upset.
2
Avoid driving or operating heavy machinery until you know how this medicine affects you.
3
Do not drink alcohol while taking this medicine.
4
Do not use this medicine for more than 7 days without consulting a doctor.
5
Stay well hydrated to help loosen mucus.
6
If you have glaucoma, prostate problems, or asthma, inform your doctor before use.
7
Keep out of reach of children.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Productive cough
This medicine is commonly prescribed for this.
Likely Use
✅
Runny nose
Chlorpheniramine helps reduce runny nose.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
❌
Dry cough
This medicine is for productive cough; not for dry cough.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBromhexine is rapidly absorbed from the gastrointestinal tract after oral administration. Chlorpheniramine is also well absorbed orally, with peak plasma concentrations occurring within 2 to 6 hours.
DistributionBromhexine is widely distributed in body tissues, including the lungs. Chlorpheniramine is distributed widely and crosses the blood-brain barrier, which accounts for its sedative effects.
Protein BindingBromhexine is approximately 95% bound to plasma proteins. Chlorpheniramine is about 72% bound to plasma proteins.
MetabolismBromhexine undergoes extensive first-pass metabolism in the liver, primarily by CYP3A4, to active metabolites. Chlorpheniramine is metabolized in the liver by CYP2D6 and other enzymes.
Half-LifeThe elimination half-life of bromhexine is approximately 6.5 hours. Chlorpheniramine has a half-life of about 12 to 43 hours, with considerable interindividual variation.
ExcretionBromhexine and its metabolites are excreted mainly in the urine. Chlorpheniramine and its metabolites are also excreted primarily in the urine.
BioavailabilityThe oral bioavailability of bromhexine is about 75-80% due to first-pass metabolism. Chlorpheniramine has a bioavailability of approximately 25-50%.
Onset of ActionBromhexine's mucolytic effect may begin within 30 minutes to 1 hour. Chlorpheniramine's antihistamine effect starts within 30 to 60 minutes.
Peak Plasma TimeBromhexine reaches peak plasma levels in about 1 hour. Chlorpheniramine peaks in 2 to 6 hours.
Duration of ActionBromhexine's effect lasts about 6 to 8 hours. Chlorpheniramine's effects last 4 to 6 hours, but sedation may persist longer.

How It Works

Bromhexine works by increasing the production of serous fluid in the respiratory tract, which helps to thin and loosen mucus, making it easier to expel. It also stimulates the production of surfactant, which reduces mucus adhesion. Chlorpheniramine maleate is a first-generation antihistamine that competes with histamine for H1-receptor sites on effector cells in the gastrointestinal tract, blood vessels, and respiratory tract. This prevents histamine-mediated symptoms such as sneezing, runny nose, and itching. The combination provides symptomatic relief of cough and cold.

Mechanism Steps

1
Bromhexine enhances mucus clearance: Bromhexine increases serous bronchial secretion and reduces mucus viscosity, making it easier to cough up.
2
Chlorpheniramine blocks histamine: Chlorpheniramine competitively blocks histamine at H1 receptors, reducing sneezing, runny nose, and itching.
3
Anticholinergic effect: Chlorpheniramine also has anticholinergic properties that dry up secretions, further relieving runny nose.
4
Sedation: Chlorpheniramine crosses the blood-brain barrier and causes drowsiness by blocking central H1 receptors.

💡 How to Take sudin sera plus tablet

Strength: Each 5 mL contains Bromhexine 4 mg and Chlorpheniramine Maleate 2 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the correct dose.
3Take the medicine orally with or without food.
4Swallow the liquid; do not chew or crush.
5Follow the recommended dose and frequency.
6Do not exceed the maximum daily dose.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 mL (two teaspoons) three to four times a day, or as directed by a physician. The dose may vary based on the severity of symptoms and individual response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and anticholinergic effects. Use with caution and consider dose reduction. Dose must be individualized by a qualified clinician.
Renal ImpairmentUse with caution in patients with renal impairment. Dose adjustment may be needed. Consult a doctor.
Hepatic ImpairmentUse with caution in patients with hepatic impairment. Dose adjustment may be needed. Consult a doctor.
Maximum Daily DoseThe maximum daily dose for adults is 40 mL (8 teaspoons) in 24 hours. Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases drowsiness and CNS depression.
Grapefruit juice
Use with caution
May increase drug levels.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of sudin sera plus tablet

✅ Common Side Effects

Drowsiness (Common (more than 10%))
Avoid driving or operating machinery. If persistent, consult your doctor.
Dry mouth (Common (5-10%))
Sip water or chew sugarless gum. Consult if severe.
Dizziness (Common (5-10%))
Rise slowly from sitting or lying position. Avoid alcohol.
Nausea (Uncommon (1-5%))
Take with food or milk. Consult if persistent.
Stomach upset (Uncommon (1-5%))
Take with meals. Consult if severe.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (less than 0.1%))
Seek immediate medical attention if you experience rash, swelling, or difficulty breathing.
Irregular heartbeat (Rare (less than 0.1%))
Contact your doctor immediately if you notice palpitations or irregular pulse.
Seizures (Very rare (less than 0.01%))
Seek emergency medical help if seizures occur.
Blood disorders (e.g., agranulocytosis) (Very rare (less than 0.01%))
Report unusual bruising, bleeding, or fever to your doctor.

⚠️ Rare Side Effects

Hallucinations
Discontinue and seek medical advice.
Photosensitivity
Use sunscreen and avoid prolonged sun exposure.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
MAO inhibitors Major
Alcohol Major
Benzodiazepines Major
Opioids Major
Tricyclic antidepressants Moderate
Fluoxetine Moderate
Paroxetine Moderate
Atropine Moderate
Antihypertensives Minor
Grapefruit juice Minor

🚨 Major Interactions

  • MAO inhibitors
  • CNS depressants (e.g., alcohol, benzodiazepines, opioids)

⚡ Moderate Interactions

  • Anticholinergics (e.g., atropine, tricyclic antidepressants)
  • CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)

🍷 Alcohol Interaction

Alcohol should be avoided while taking this medicine because it can significantly increase drowsiness, dizziness, and impairment of motor skills. Combining alcohol with chlorpheniramine can also increase the risk of central nervous system depression.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to bromhexine, chlorpheniramine, or any component of the formulation","Narrow-angle glaucoma","Prostatic hypertrophy with urinary retention","Bladder neck obstruction","Severe asthma or respiratory depression","MAO inhibitor therapy within 14 days","Children under 12 years (unless directed by a physician)"]

⚠️ Warnings & Precautions

["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with glaucoma, prostatic hypertrophy, or urinary retention.","Use with caution in patients with asthma or COPD.","Do not use for chronic cough or cough with excessive secretions.","Consult a doctor if symptoms persist beyond 7 days or worsen.","Keep out of reach of children.","Do not exceed the recommended dose."]

🤱 Lactation Safety

Chlorpheniramine and bromhexine may pass into breast milk. Consult your doctor before use during breastfeeding. It may cause drowsiness in the infant.

💊 Overdose Management

Overdose may cause severe drowsiness, confusion, hallucinations, seizures, respiratory depression, and cardiac arrhythmias. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have a history of asthma, glaucoma, difficulty urinating due to an enlarged prostate, thyroid problems, heart disease, or high blood pressure. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause drowsiness. Do not drink alcohol while taking this medicine, as it can increase drowsiness and other side effects. This medicine may interact with other medications, including sedatives, antidepressants, and MAO inhibitors. Do not use this medicine for more than 7 days without consulting a doctor. Keep out of reach of children. If you are pregnant or breastfeeding, consult your doctor before use. Do not exceed the recommended dose.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are more sensitive to the sedative and anticholinergic effects of chlorpheniramine. They may experience increased drowsiness, confusion, dry mouth, and urinary retention. Use with caution and consider a lower dose. Consult a doctor before use.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this medicine during pregnancy is not well established. Your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. It may interact with anesthetic agents and increase sedation. It is usually recommended to stop this medicine a few days before surgery, as advised by your doctor.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It can cause dry mouth, which may increase the risk of dental problems. Also, the sedative effect may interact with sedatives used during dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Use a humidifier to add moisture to the air.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to support recovery.
🧘
Gargle with warm salt water to soothe a sore throat.
🌞
Avoid alcohol and sedatives while taking this medicine.

🏋️ Exercise Considerations

Avoid strenuous exercise while taking this medicine, as it can cause drowsiness and dizziness. Light activity is fine if you feel up to it, but listen to your body and rest when needed.

🥗 Diet Recommendations

Drink warm fluids like herbal tea and soup.
Include honey and ginger to soothe the throat.
Avoid cold and sugary drinks that can irritate the throat.
Eat light, nutritious meals.
Avoid processed foods that can increase mucus production.

💼 Impact on Daily Work & Life

This medicine can cause drowsiness, which may affect your ability to work, especially if your job requires alertness or operating machinery. Consider taking it at bedtime or when you don't need to be active. Avoid driving until you know how it affects you.

🛑 When to Stop This Medicine

Stop taking this medicine and consult a doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects such as severe drowsiness, irregular heartbeat, or allergic reactions.

📅 Long-Term Use Effects

Long-term use of this medicine is not recommended. Prolonged use of chlorpheniramine can lead to tolerance, dependence, and cognitive impairment. Bromhexine is generally safe for short-term use. Regular monitoring of liver and kidney function may be needed if used for extended periods. Consult your doctor for alternative treatments if symptoms persist.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Helps loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal spray

Moisturizes nasal passages and reduces congestion.

Evidence: Well-established
Honey and lemon

Soothes sore throat and cough.

Evidence: Traditional

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are unwell with a fever, it is advisable to postpone vaccination until you recover.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of the prescription. Store at room temperature and protect from light. If traveling across time zones, adjust dosing schedule accordingly, but do not exceed the maximum daily dose. Check customs regulations for carrying medications.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with a productive cough and runny nose
He was prescribed this medicine for 5 days. He noticed significant relief in cough and nasal congestion within 2 days. He experienced mild drowsiness, so he took it at bedtime. He was advised to drink plenty of fluids.
💡 Lesson: Taking the medicine at bedtime can help manage drowsiness during the day.
👤 A 50-year-old woman with allergic rhinitis and cough
She used this medicine as directed and found relief from sneezing and cough. She was cautioned about driving due to drowsiness. She avoided alcohol and felt better within a week.
💡 Lesson: Following safety precautions and avoiding alcohol enhances tolerability.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine starts working within 30 to 60 minutes, with peak effects in 2 to 6 hours.

Q: Can I take this medicine with food?

A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.

Q: Is it safe to drive after taking this medicine?

A: No, this medicine can cause drowsiness. Avoid driving or operating machinery until you know how it affects you.

Q: How long can I continue this medicine?

A: Do not use for more than 7 days without consulting a doctor. If symptoms persist, seek medical advice.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for sudin sera plus tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Anticold linctus can cure the common cold.
    Fact: It only relieves symptoms; it does not cure the underlying viral infection.
  • Myth: It is safe to take with alcohol.
    Fact: Alcohol increases drowsiness and other side effects; avoid combining.
  • Myth: It can be used for any type of cough.
    Fact: It is for productive cough with thick mucus; not for dry cough.

🔄 Alternative Options

Generic Alternatives

  • Bromhexine + Chlorpheniramine Maleate Linctus

📊 Comparison with Similar Medicines

[{"medicine":"Bromhexine + Chlorpheniramine","uses":"Productive cough with allergy symptoms","sedation":"Moderate to high","notes":"Combination for cough and cold."},{"medicine":"Bromhexine alone","uses":"Productive cough","sedation":"None","notes":"No antihistamine effect."},{"medicine":"Chlorpheniramine alone","uses":"Allergic rhinitis","sedation":"High","notes":"No mucolytic effect."}]

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