sucratas-o oral suspension - Sucralfate (1gm/5ml) + Oxetacaine (10mg) medicine

Sucratas-O Oral Suspension: Complete Medicine Guide

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🏭 Intas Pharmaceuticals Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate to well-established for sucralfate in acid-peptic disorders; limited for oxetacaine combination.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain or distension
  • Difficulty breathing or swelling of face, lips, or throat
  • Signs of aluminium toxicity: confusion, muscle weakness, bone pain
  • Persistent vomiting or inability to keep fluids down
  • Yellowing of skin or eyes (jaundice)

If experiencing severe symptoms, call emergency services immediately.

What is sucratas-o oral suspension used for?

This medicine is a combination of sucralfate and oxetacaine used to treat acid reflux, gastritis, and ulcers. It works by forming a protective barrier over the stomach lining and numbing pain.

  • Generic Name: Sucralfate (1gm/5ml) + Oxetacaine (10mg)
  • Manufacturer: Intas Pharmaceuticals Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 sucratas-o oral suspension के बारे में (Hindi Summary)

उपयोग: यह दवा सुक्राल्फेट और ऑक्सेटाकेन का संयोजन है, जिसका उपयोग एसिड रिफ्लक्स, गैस्ट्रिटिस और अल्सर के इलाज के लिए किया जाता है। यह पेट की परत पर एक सुरक्षात्मक परत बनाती है और दर्द को कम करती है।

साइड इफेक्ट्स: आम दुष्प्रभावों में कब्ज, मुँह सूखना, मतली और हल्का पेट दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी प्रतिक्रिया हो सकती है।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार लें। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। अन्य दवाओं के साथ लेने से पहले 2 घंटे का अंतराल रखें। गुर्दे की बीमारी हो तो डॉक्टर को बताएं।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 sucratas-o oral suspension Uses & Benefits

[{"condition":"Gastroesophageal reflux disease (GERD)","description":"Provides symptomatic relief from heartburn and acid regurgitation by protecting the oesophageal lining and numbing irritated areas.","evidence":"Well-established"},{"condition":"Gastritis","description":"Helps reduce pain and inflammation of the stomach lining by forming a protective barrier.","evidence":"Well-established"},{"condition":"Peptic ulcer disease","description":"Aids in ulcer healing by protecting the ulcer base from acid and pepsin, and provides pain relief.","evidence":"Well-established"},{"condition":"Oesophagitis","description":"Soothes inflammation of the food pipe and reduces pain on swallowing.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Mucositis due to chemotherapy or radiation","description":"Sometimes used to relieve mouth and throat pain in patients undergoing cancer treatment.","evidence":"Limited"},{"condition":"Stress ulcer prophylaxis","description":"Occasionally used in critically ill patients to prevent stress-related mucosal bleeding.","evidence":"Limited"}]

Primary treatment for: Gastroesophageal reflux disease (GERD)

Also treats: Gastritis, Peptic ulcer disease, Oesophagitis

📋 Drug Information

Generic Name(s)Sucralfate (1gm/5ml) + Oxetacaine (10mg)
Brand Namesucratas-o oral suspension
ManufacturerIntas Pharmaceuticals Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGASTRO INTESTINAL
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight. Do not freeze.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine on an empty stomach, at least 1 hour before meals or 2 hours after meals.
2
Shake the bottle well before each dose to ensure proper mixing.
3
Separate this medicine from other medications by at least 2 hours to avoid absorption issues.
4
Avoid alcohol and smoking as they can worsen your stomach condition.
5
If you have kidney problems, inform your doctor before starting this medicine.
6
Do not exceed the prescribed dose or duration without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heartburn
This medicine is commonly prescribed for this.
Likely Use
✅
Stomach pain
This medicine can help relieve stomach pain due to ulcers or gastritis.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionSucralfate is minimally absorbed from the gastrointestinal tract; only about 3-5% of aluminium is absorbed. Oxetacaine is also poorly absorbed systemically when taken orally, exerting its effects locally.
DistributionBecause systemic absorption is minimal, distribution of sucralfate and oxetacaine to body tissues is negligible. Any absorbed aluminium is distributed mainly to bone and brain.
Protein BindingNot established from the available information.
MetabolismSucralfate is not significantly metabolised; it is excreted unchanged in faeces. Oxetacaine is likely metabolised in the liver, but specific data are not well established.
Half-LifeNot established from the available information.
ExcretionMost of sucralfate is excreted unchanged in the faeces. Any absorbed aluminium is excreted primarily in the urine. Oxetacaine is likely excreted via the kidneys after hepatic metabolism.
BioavailabilityOral bioavailability of sucralfate is very low (less than 5%). Oxetacaine has low systemic bioavailability when taken orally.
Onset of ActionThe local anaesthetic effect of oxetacaine begins within minutes of ingestion, providing rapid pain relief. The protective effect of sucralfate starts soon after reaching the stomach.
Peak Plasma TimeNot established from the available information.
Duration of ActionThe protective barrier lasts for approximately 6 hours, but the anaesthetic effect may wear off sooner. Dosing is usually every 6 hours or as directed.

How It Works

Sucralfate is a complex of aluminium hydroxide and sucrose sulphate. In the acidic environment of the stomach, it polymerises to form a viscous, sticky paste that selectively binds to damaged mucosa and ulcer craters, creating a physical barrier against acid, pepsin, and bile salts. It also inhibits pepsin activity and may stimulate local prostaglandin synthesis, enhancing mucosal defence. Oxetacaine is a local anaesthetic that blocks sodium channels in nerve endings, reducing pain signals from the irritated mucosa. Together, they provide both protection and rapid symptomatic relief.

Mechanism Steps

1
Polymerisation and coating: In the acidic stomach, sucralfate polymerises and forms a protective layer over ulcers and inflamed tissue.
2
Barrier formation: The coating blocks acid, pepsin, and bile salts from further irritating the damaged mucosa.
3
Local anaesthesia: Oxetacaine numbs the sensory nerve endings in the mucosa, reducing pain and burning.
4
Mucosal protection: Sucralfate may also stimulate prostaglandin release, enhancing mucosal defence and healing.

💡 How to Take sucratas-o oral suspension

Strength: Each 5 mL contains sucralfate 1 g and oxetacaine 10 mg.

1Shake the bottle well before each use.
2Measure the prescribed dose using the measuring cup or spoon provided.
3Take it on an empty stomach, at least 1 hour before meals or 2 hours after meals.
4Swallow the suspension; do not chew or crush.
5Do not eat or drink anything for at least 30 minutes after taking the dose.
6If you are taking other medicines, take them at least 2 hours apart from this medicine.

Dosage Information

Adult DosageThe usual adult dose is 10 mL (containing 1 g sucralfate and 10 mg oxetacaine) taken orally four times a day, preferably on an empty stomach, one hour before meals and at bedtime. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the effects of this medicine, especially if they have reduced renal function. Dose adjustment may be necessary based on kidney function. Consult your doctor.
Renal ImpairmentUse with caution in patients with renal impairment. Sucralfate may accumulate and cause aluminium toxicity. Dose reduction or avoidance may be required. Consult your doctor for individualized dosing.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Consult your doctor.
Maximum Daily DoseThe maximum recommended daily dose is 40 mL (4 g sucralfate and 40 mg oxetacaine) in divided doses, but this may vary based on clinical judgment.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Avoid taking with food
Food reduces the protective barrier formation of sucralfate.
Citrus fruits and juices
Avoid within 1 hour of dose
May increase stomach acidity and reduce efficacy.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of sucratas-o oral suspension

✅ Common Side Effects

Constipation (Common (5-10%))
Increase fibre and fluid intake. Consult doctor if persistent.
Dry mouth (Common (5-10%))
Sip water frequently. Usually resolves on its own.
Nausea (Common (5-10%))
Take with food if not contraindicated. Consult doctor if severe.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you know how it affects you.

🚨 Serious Side Effects

Allergic reaction (rash, swelling, difficulty breathing) (Rare (<0.1%))
Seek immediate medical attention.
Aluminium toxicity (in renal impairment) (Rare (<0.1%))
Report symptoms like confusion, muscle weakness, or bone pain to your doctor.
Bezoar formation (rare, especially in patients with delayed gastric emptying) (Very rare (<0.01%))
Seek medical attention if you experience persistent vomiting or abdominal distension.

⚠️ Rare Side Effects

Hypophosphataemia
Monitor phosphate levels if on long-term therapy.
Encephalopathy due to aluminium accumulation
Seek immediate medical attention if confusion or seizures occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Ciprofloxacin Major
Tetracycline Major
Levothyroxine Major
Digoxin Moderate
Warfarin Moderate
Ketoconazole Moderate
Antacids Minor
Phenytoin Minor

🚨 Major Interactions

  • Fluoroquinolone antibiotics (e.g., ciprofloxacin, levofloxacin)
  • Tetracycline antibiotics
  • Levothyroxine

⚡ Moderate Interactions

  • Digoxin
  • Warfarin
  • Ketoconazole

🍷 Alcohol Interaction

Alcohol can irritate the stomach lining and worsen your underlying condition. It is best to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to sucralfate or oxetacaine","Severe renal impairment or dialysis","Suspected or confirmed gastrointestinal obstruction","Premature infants and neonates"]

⚠️ Warnings & Precautions

["Use with caution in patients with renal impairment; risk of aluminium accumulation.","May interfere with absorption of other medications; separate dosing times.","Not recommended for long-term use without medical supervision.","Avoid in patients with delayed gastric emptying or bezoar risk.","Do not use if the suspension appears discoloured or has particles."]

🤱 Lactation Safety

It is not known whether sucralfate or oxetacaine pass into breast milk in significant amounts. Consult your doctor before using this medicine while breastfeeding.

💊 Overdose Management

Overdose is unlikely to cause serious effects due to poor systemic absorption. However, in large amounts, it may cause gastrointestinal discomfort, constipation, or aluminium toxicity in renal patients. Seek medical attention if large amounts are ingested. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Shake the bottle well before each dose to ensure the medicine is evenly mixed. Do not take it within two hours of other medicines, as sucralfate can reduce their absorption. Avoid alcohol and smoking while on this medicine because they can worsen your stomach condition. If you have kidney problems, tell your doctor before starting this medicine. Do not drive or operate heavy machinery if you feel dizzy or drowsy after taking it. Keep out of reach of children and store in a cool, dry place.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to constipation and aluminium accumulation, especially if they have reduced kidney function. Dose adjustment and monitoring may be required.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before using this medicine. Sucralfate is generally considered safe, but oxetacaine data are limited.

🏥 Post-Surgery Considerations

After surgery, use this medicine only if prescribed by your surgeon. It may be used to protect the stomach lining, but ensure no interactions with other post-operative medications.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It is generally safe for dental procedures, but the local anaesthetic component may interact with other anaesthetics.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce pressure on the stomach.
🥗
Avoid lying down immediately after meals.
😴
Eat smaller, more frequent meals.
💧
Avoid spicy, fatty, and acidic foods.
🧘
Quit smoking and limit alcohol.
🌞
Manage stress through relaxation techniques.

🏋️ Exercise Considerations

Avoid vigorous exercise immediately after taking this medicine, especially if you feel dizzy. Mild to moderate exercise is generally safe.

🥗 Diet Recommendations

Include fibre-rich foods to prevent constipation.
Stay well hydrated.
Avoid caffeine and carbonated drinks.
Eat bland, non-spicy foods.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not significantly impact your daily work if taken as prescribed.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. Usually, it is prescribed for a limited duration.

📅 Long-Term Use Effects

Long-term use of sucralfate may lead to aluminium accumulation, especially in patients with kidney disease, potentially causing bone or brain toxicity. Regular monitoring of renal function and aluminium levels is advised. Oxetacaine long-term effects are not well established. Use only as prescribed and for the recommended duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Proton pump inhibitors

Reduce stomach acid production and are often used for GERD and ulcers.

Evidence: Well-established
H2 receptor blockers

Reduce acid secretion and provide relief from heartburn.

Evidence: Well-established
Lifestyle modifications

Diet changes, weight loss, and avoiding trigger foods can help manage symptoms.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Continue routine vaccinations as scheduled.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If travelling across time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage to avoid temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old man with chronic GERD
He was prescribed this medicine for persistent heartburn. After taking it regularly before meals, his symptoms improved significantly within a week. He noted that taking it on an empty stomach was key to its effectiveness.
💡 Lesson: Taking sucralfate-containing suspensions on an empty stomach enhances their protective effect.
👤 A 60-year-old woman with gastritis and mild kidney disease
She started this medicine but developed constipation and mild dizziness. Her doctor adjusted the dose and monitored her kidney function. She was advised to increase fluid and fibre intake.
💡 Lesson: Elderly patients and those with kidney issues need careful monitoring and dose adjustment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: The local anaesthetic effect starts within minutes, providing rapid pain relief. The protective effect begins soon after ingestion.

Q: Can I take it with other medicines?

A: It can interfere with absorption of many medicines. Take other medicines at least 2 hours before or after this medicine.

Q: Is it safe during pregnancy?

A: Sucralfate is generally considered safe in pregnancy. Oxetacaine has limited data. Consult your doctor before use.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🛑 Myths vs. Facts

  • Myth: It can be taken with any other medicine at the same time.
    Fact: It can interfere with absorption of many medicines; separate by at least 2 hours.
  • Myth: It is safe for long-term use without monitoring.
    Fact: Long-term use requires monitoring, especially of kidney function and aluminium levels.

🔄 Alternative Options

Generic Alternatives

  • Sucralfate + Oxetacaine oral suspension (generic)

📊 Comparison with Similar Medicines

[{"medicine":"Sucralfate + Oxetacaine","class":"Gastroprotective + local anaesthetic","main_use":"GERD, gastritis, ulcers","onset":"Rapid","duration":"6 hours"},{"medicine":"Proton pump inhibitors","class":"Acid suppressant","main_use":"GERD, ulcers","onset":"1-2 hours","duration":"24 hours"}]

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