Asomex CV 5mg/10mg Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Unexplained muscle pain, tenderness, or weakness
- Dark or cola-colored urine
- Yellowing of skin or eyes (jaundice)
- Severe abdominal pain, nausea, or vomiting
- Signs of allergic reaction: rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing
- Severe dizziness or fainting
- Irregular heartbeat or palpitations
- Sudden weight gain or swelling in ankles or feet
If experiencing severe symptoms, call emergency services immediately.
What is storvas amf 5mg/10mg tablet used for?
This medicine is a combination of Amlodipine 5 mg and Atorvastatin 10 mg used to treat high blood pressure and high cholesterol. It is taken orally once daily, usually with food. It works by relaxing blood vessels and reducing cholesterol production in the liver. Common side effects include ankle swelling, headache, and dizziness. It is contraindicated in pregnancy and liver disease.
- Generic Name: Amlodipine (5mg) + Atorvastatin (10mg)
- Manufacturer: Sun Pharmaceutical Industries Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 storvas amf 5mg/10mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एम्लोडिपिन 5 मिलीग्राम और एटोरवास्टेटिन 10 मिलीग्राम का संयोजन है। इसका उपयोग उच्च रक्तचाप (हाई ब्लड प्रेशर) और उच्च कोलेस्ट्रॉल (हाई कोलेस्ट्रॉल) के इलाज के लिए किया जाता है। यह रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करती है और लीवर में कोलेस्ट्रॉल बनने को रोककर कोलेस्ट्रॉल को कम करती है। यह दवा हृदय रोग, स्ट्रोक और दिल के दौरे के जोखिम को कम करने में मदद करती है। इसे रोजाना एक बार भोजन के साथ लेना चाहिए। गर्भवती महिलाओं, स्तनपान कराने वाली महिलाओं और लीवर रोग वाले मरीजों को यह दवा नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में टखनों या पैरों में सूजन, सिरदर्द, चक्कर आना, थकान और पेट में हल्की परेशानी शामिल हैं। कुछ गंभीर दुष्प्रभाव भी हो सकते हैं जैसे मांसपेशियों में तेज दर्द या कमजोरी, गहरे रंग का पेशाब, आंखों या त्वचा का पीला पड़ना, और एलर्जी की प्रतिक्रिया। अगर आपको कोई भी गंभीर लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। अपने आप डोज न बदलें और न ही दवा लेना बंद करें। इसे हर दिन एक ही समय पर लें, भोजन के साथ लेना बेहतर है। ग्रेपफ्रूट या ग्रेपफ्रूट जूस का सेवन न करें। शराब का सेवन सीमित करें या बिल्कुल न करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। नियमित रूप से रक्तचाप, कोलेस्ट्रॉल और लीवर फंक्शन की जांच कराएं। गर्भवती या स्तनपान कराने वाली महिलाएं इस दवा का सेवन न करें।
💊 storvas amf 5mg/10mg tablet Uses & Benefits
[{"condition":"Hypertension with dyslipidemia","description":"Used to lower blood pressure and simultaneously reduce elevated LDL cholesterol and triglycerides in patients who require both treatments.","evidence":"Well-established"},{"condition":"Cardiovascular risk reduction","description":"Helps reduce the risk of heart attack, stroke, and other cardiovascular events in patients with multiple risk factors.","evidence":"Well-established"},{"condition":"Angina prophylaxis with hyperlipidemia","description":"Amlodipine component helps prevent angina attacks, while atorvastatin manages cholesterol levels.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Raynaud's phenomenon","description":"Amlodipine may be used off-label to reduce frequency and severity of Raynaud's attacks, but this combination is not specifically approved for this use.","evidence":"Limited"},{"condition":"Diabetic nephropathy prevention","description":"Some clinicians use this combination for renal protection in diabetic patients with hypertension and dyslipidemia, but it is not a labeled indication.","evidence":"Limited"}]
Primary treatment for: Hypertension with dyslipidemia
Also treats: Angina, Coronary artery disease, Diabetes with cardiovascular risk
📋 Drug Information
| Generic Name(s) | Amlodipine (5mg) + Atorvastatin (10mg) |
| Brand Name | storvas amf 5mg/10mg tablet |
| Manufacturer | Sun Pharmaceutical Industries Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Amlodipine is a dihydropyridine calcium channel blocker that inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle cells. This leads to relaxation of peripheral arterioles, reduction in peripheral vascular resistance, and lowering of blood pressure. Atorvastatin is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts HMG-CoA to mevalonate, a precursor of cholesterol. By inhibiting this enzyme, atorvastatin reduces cholesterol synthesis in the liver and upregulates LDL receptors, increasing clearance of LDL cholesterol from the blood. Together, these actions provide complementary cardiovascular benefits.
Mechanism Steps
💡 How to Take storvas amf 5mg/10mg tablet
Strength: Tablet containing Amlodipine 5 mg and Atorvastatin 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet of Amlodipine 5 mg and Atorvastatin 10 mg taken orally once daily, with or without food. However, the dose may be adjusted by your doctor based on your blood pressure and cholesterol levels. Some patients may require higher strengths or additional medications. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not change the dose without consulting your doctor. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of amlodipine, especially dizziness and hypotension. Start with lower doses and monitor closely. Atorvastatin dose adjustments are generally not required based on age alone, but liver and kidney function should be considered. |
| Renal Impairment | No dosage adjustment is required for amlodipine in renal impairment. Atorvastatin does not require dosage adjustment in mild to moderate renal impairment, but caution is advised in severe renal impairment. Monitor renal function. |
| Hepatic Impairment | Amlodipine should be used with caution in patients with hepatic impairment; start with lower doses. Atorvastatin is contraindicated in active liver disease or unexplained persistent transaminase elevations. In patients with chronic liver disease, use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose for this specific combination is one tablet of Amlodipine 5 mg and Atorvastatin 10 mg. Higher strengths are available and may be prescribed by your doctor. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of storvas amf 5mg/10mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Clarithromycin | Major | |
| Itraconazole | Major | |
| Cyclosporine | Major | |
| Gemfibrozil | Major | |
| Warfarin | Moderate | |
| Digoxin | Moderate | |
| Grapefruit juice | Moderate | |
| Antacids | Minor | |
| Oral contraceptives | Minor | |
| Rifampicin | Moderate |
🚨 Major Interactions
- Strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole, ritonavir)
- Cyclosporine
- Gemfibrozil
⚡ Moderate Interactions
- Grapefruit juice
- Warfarin
- Digoxin
🍷 Alcohol Interaction
Alcohol may increase the risk of liver damage when taken with atorvastatin and can worsen blood pressure control. It is advisable to limit or avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to amlodipine, atorvastatin, or any component of the formulation","Active liver disease or unexplained persistent elevations of serum transaminases","Pregnancy and breastfeeding","Concomitant use with strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole) if risk outweighs benefit","Severe hypotension"]
⚠️ Warnings & Precautions
["Monitor for muscle pain, tenderness, or weakness; report promptly.","Avoid grapefruit juice and grapefruit products.","Limit alcohol consumption.","Use with caution in patients with liver disease or a history of liver disease.","Use with caution in elderly patients and those with renal impairment.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not stop taking this medicine abruptly without consulting your doctor.","Inform your doctor if you are taking any other medications, especially those affecting CYP3A4."]
🤱 Lactation Safety
This medicine is not recommended during breastfeeding. Both amlodipine and atorvastatin may pass into breast milk and could harm the nursing infant. Consult your doctor for alternative treatments.
💊 Overdose Management
Overdose may cause severe hypotension, dizziness, and muscle toxicity. Seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Hemodialysis is not effective for removing amlodipine or atorvastatin.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your doctor, even if you feel well. High blood pressure and high cholesterol often have no symptoms, so you may not feel any different when you miss doses. Take this tablet at the same time each day, with or without food, but preferably with food to reduce stomach upset. Avoid drinking grapefruit juice or eating grapefruit while on this medicine, as it can increase the levels of atorvastatin in your body and raise the risk of side effects. Limit or avoid alcohol consumption, as it can increase the risk of liver problems and may worsen blood pressure control. Inform your doctor about all other medicines, supplements, and herbal products you are taking, especially other blood pressure medicines, cholesterol medicines, certain antibiotics, antifungals, and antidepressants. If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor immediately. Regular monitoring of blood pressure, cholesterol levels, and liver function tests is important while taking this medicine. Do not share this medicine with anyone else, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of amlodipine. Start with lower doses and monitor closely for dizziness and falls. Liver and kidney function should be assessed regularly.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. Women planning pregnancy should consult their doctor to switch to safer alternatives before conception.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth or bleeding gums. Maintain good oral hygiene.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is encouraged, but if you experience dizziness or muscle pain, stop and consult your doctor. Avoid strenuous exercise if you have muscle symptoms.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not affect your ability to work otherwise.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects, contact your doctor immediately. Your doctor may adjust the dose or switch to another medicine.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and beneficial for managing blood pressure and cholesterol. Regular monitoring of liver function, lipid profile, and blood pressure is recommended. Rarely, long-term atorvastatin use may be associated with an increased risk of diabetes and muscle problems. Do not stop the medicine without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and weight loss can help manage blood pressure and cholesterol.
Evidence: Well-establishedAlternative classes like ARBs, ACE inhibitors, or other statins may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. Continue routine vaccinations as recommended by your doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, continue taking your dose at the same local time as much as possible. Consult your doctor if you need to adjust timing. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: Amlodipine starts lowering blood pressure within 24-48 hours, with full effect in 1-2 weeks. Atorvastatin starts reducing cholesterol in about 2 weeks, with maximum effect at 4-6 weeks.
A: Yes, it can be taken at night if your doctor advises. Some people experience dizziness, so taking it at night may help.
A: Avoid grapefruit and grapefruit juice, limit alcohol, and do not take other medications without consulting your doctor.
A: Yes, it is generally safe for long-term use with regular monitoring of blood pressure, cholesterol, and liver function.
🤔 Common Patient Concerns
🔄 Substitutes for storvas amf 5mg/10mg tablet
View AllAlternative brands with exact same active ingredient:
-
a2 5mg/10mg tabletZydus Cadila ₹32.12 52.5% CHEAPER
-
a2 5 mg/10 mg tabletZydus Cadila ₹37.52 44.5% CHEAPER
-
amat 5mg/10mg tabletAbbott ₹40.00 40.9% CHEAPER
-
zivast-am tabletFDC Ltd ₹44.06 34.9% CHEAPER
-
lipikind am 5 mg/10 mg tabletMankind Pharma Ltd ₹44.58 34.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure high blood pressure and high cholesterol permanently.
Fact: This medicine manages these conditions but does not cure them. Lifestyle changes and continued medication are often necessary. - Myth: You can stop taking this medicine once your blood pressure and cholesterol are normal.
Fact: Stopping suddenly can cause rebound high blood pressure and increased cardiovascular risk. Always consult your doctor before stopping. - Myth: This medicine causes kidney damage.
Fact: This medicine is not directly harmful to kidneys, but regular monitoring is advised. Rhabdomyolysis, a rare side effect, can affect kidneys.
🔄 Alternative Options
Generic Alternatives
- Amlodipine 5 mg + Atorvastatin 10 mg generic tablets
Brand Alternatives
- Not established from the available information.