Epsolin 150mg Tablet ER: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Rash, blisters, peeling skin, or sores in the mouth or eyes
- Yellowing of the eyes or skin, dark urine, or severe abdominal pain
- Unusual bruising, bleeding, fever, or sore throat
- Swelling of the face, lips, tongue, or throat, or difficulty breathing
- Severe dizziness, confusion, slurred speech, or unsteady walking
- Seizures that are different, more frequent, or more severe than usual
- Chest pain, palpitations, or fainting
If experiencing severe symptoms, call emergency services immediately.
What is Stoin 150mg Tablet used for?
This medicine is an extended-release tablet containing phenytoin, used to control certain types of seizures. It works by stabilizing electrical activity in the brain. It must be taken exactly as prescribed, and regular blood monitoring is required.
- Generic Name: Phenytoin (150mg)
- Manufacturer: Sunrise Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Stoin 150mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा फेनिटोइन नामक सक्रिय तत्व वाली एक्सटेंडेड-रिलीज़ गोली है, जिसका उपयोग मिर्गी के दौरे (seizures) को नियंत्रित करने के लिए किया जाता है। यह मुख्य रूप से जनरलाइज़्ड टॉनिक-क्लोनिक दौरे और कॉम्प्लेक्स पार्शियल दौरों के इलाज में प्रभावी है। यह दवा मस्तिष्क में असामान्य विद्युत गतिविधि को स्थिर करके दौरे पड़ने की संभावना को कम करती है। इसे रोज़ एक ही समय पर लेना बहुत ज़रूरी है, और डॉक्टर की सलाह के बिना इसे अचानक बंद नहीं करना चाहिए, क्योंकि इससे दौरे बढ़ सकते हैं। इस दवा को लेते समय नियमित रूप से खून की जांच करानी पड़ती है ताकि दवा का स्तर और लीवर की स्थिति की निगरानी हो सके।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, नींद आना, अस्थिरता, सिरदर्द, जी मिचलाना, उल्टी, कब्ज़ और हल्के त्वचा दाने शामिल हैं। लंबे समय तक उपयोग से मसूड़ों में सूजन, चेहरे और शरीर पर बाल बढ़ना, और चेहरे की विशेषताओं में बदलाव हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें त्वचा पर गंभीर दाने, छाले, त्वचा का छिलना, लीवर की क्षति (पीलिया, गहरे रंग का पेशाब), खून की बीमारियाँ (असामान्य चोट या खून बहना), और गंभीर एलर्जी प्रतिक्रियाएँ शामिल हो सकती हैं। इनमें से कोई भी लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, हर दिन एक ही समय पर। एक्सटेंडेड-रिलीज़ गोली को पूरा निगलें, चबाएं या तोड़ें नहीं। इसे अचानक बंद न करें, क्योंकि इससे दौरे बढ़ सकते हैं। नियमित रूप से खून की जांच कराएं ताकि दवा का स्तर, लीवर और खून की निगरानी हो सके। अपने डॉक्टर को अन्य सभी दवाओं, सप्लीमेंट्स और हर्बल उत्पादों के बारे में बताएं। शराब से बचें। यदि आप गर्भवती हैं या गर्भधारण की योजना बना रही हैं, तो डॉक्टर से सलाह लें। त्वचा पर दाने, मुंह में छाले, बुखार, आंखों का पीलापन या असामान्य खून बहना दिखने पर तुरंत डॉक्टर से मिलें। जब तक पता न चले कि यह दवा आपको कैसे प्रभावित करती है, वाहन न चलाएं।
💊 Stoin 150mg Tablet Uses & Benefits
[{"condition":"Generalized tonic-clonic seizures","description":"This medicine is used to prevent and control generalized tonic-clonic seizures in adults and children.","evidence":"Well-established"},{"condition":"Complex partial seizures","description":"It helps reduce the frequency of complex partial seizures, with or without secondary generalization.","evidence":"Well-established"},{"condition":"Simple partial seizures","description":"This medicine may be used to control simple partial seizures in some patients.","evidence":"Established"},{"condition":"Seizure prophylaxis in neurosurgery","description":"It is sometimes used short-term to prevent seizures around brain surgery or after head trauma.","evidence":"Established in specific settings"},{"condition":"Status epilepticus","description":"An injectable form of phenytoin is used in emergency settings for status epilepticus, but this oral extended-release tablet is not for acute treatment.","evidence":"Well-established for injectable form"}]
Off-label uses: [{"condition":"Trigeminal neuralgia","description":"Sometimes prescribed off-label for facial pain from trigeminal neuralgia when other treatments are not effective.","evidence":"Limited"},{"condition":"Certain cardiac arrhythmias","description":"Historically used for some ventricular arrhythmias, but safer alternatives are now preferred.","evidence":"Limited and largely superseded"},{"condition":"Migraine prophylaxis","description":"Occasionally used off-label to prevent migraines, but not a first-line option.","evidence":"Limited"}]
Primary treatment for: Epilepsy
Also treats: Generalized tonic-clonic seizures, Complex partial seizures, Simple partial seizures
📋 Drug Information
| Generic Name(s) | Phenytoin (150mg) |
| Brand Name | Stoin 150mg Tablet |
| Manufacturer | Sunrise Remedies Pvt Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container, tightly closed. |
| Shelf Life | Typically 24 to 36 months from the date of manufacture, depending on the manufacturer. Check the expiry date on the pack. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking voltage-gated sodium channels in the brain and nervous system. During a seizure, brain cells fire abnormally and repeatedly. By stabilizing these sodium channels, this medicine reduces the ability of neurons to fire at high frequencies, which helps prevent the spread of seizure activity. It also affects calcium channels and other cellular processes, but the main antiepileptic effect comes from its action on sodium channels. This medicine does not cure epilepsy; it controls the abnormal electrical activity that leads to seizures.
Mechanism Steps
💡 How to Take Stoin 150mg Tablet
Strength: Extended-release tablet, 150 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is individualized by a qualified clinician based on seizure type, response, and blood levels. A common starting dose is 100 mg three times daily or 300 mg once daily of the extended-release form, but the dose may be adjusted gradually. The target therapeutic blood level is usually 10 to 20 mcg/mL. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and concomitant medicines. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this specific extended-release tablet. Consult a pediatrician or pediatric neurologist for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may require lower doses because of reduced liver metabolism and increased sensitivity to side effects. Dose must be individualized by a qualified clinician based on renal and hepatic function, and blood levels should be monitored closely. |
| Renal Impairment | No specific dose adjustment is established for renal impairment, but this medicine should be used with caution. Monitor blood levels and watch for signs of toxicity. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In patients with liver disease, the dose of this medicine should be reduced and blood levels monitored closely because metabolism is impaired. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose is individualized and should not exceed the dose determined by your clinician based on blood levels. In general, doses above 600 mg per day are rarely used, and the risk of toxicity increases with higher doses. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Stoin 150mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Oral contraceptives | Major | |
| Carbamazepine | Major | |
| Valproic acid | Major | |
| Fluconazole | Major | |
| Rifampin | Major | |
| Cimetidine | Moderate | |
| Omeprazole | Moderate | |
| Diazepam | Moderate | |
| Furosemide | Moderate |
🚨 Major Interactions
- Warfarin
- Oral contraceptives
- Carbamazepine
- Valproic acid
- Fluconazole
- Rifampin
⚡ Moderate Interactions
- Cimetidine
- Omeprazole
- Diazepam
- Furosemide
- Doxycycline
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness and dizziness, and it can also affect seizure control and phenytoin levels. Chronic heavy alcohol use can decrease phenytoin levels, while acute alcohol intake can increase them, making seizure control unpredictable.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to phenytoin or other hydantoins","History of porphyria","Sinus bradycardia, sinoatrial block, second- or third-degree AV block, or Adams-Stokes syndrome","Concurrent use with delavirdine","Pregnancy, unless the benefits clearly outweigh the risks"]
⚠️ Warnings & Precautions
["Do not stop this medicine suddenly, as it can cause withdrawal seizures.","Serious skin reactions can occur; stop the medicine and seek immediate medical attention if a rash develops.","This medicine can cause liver damage; regular monitoring is required.","Blood disorders can occur; report unusual bruising, bleeding, or fever.","This medicine can interact with many other medicines; always inform your doctor about all medicines you take.","Use with caution in elderly patients, who may be more sensitive to side effects.","This medicine can affect blood sugar levels; monitor if you have diabetes.","Avoid alcohol while taking this medicine.","This medicine may impair your ability to drive or operate machinery.","Extended-release tablets must be swallowed whole; do not crush or chew."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. Breastfeeding is generally considered acceptable while taking this medicine, but the baby should be monitored for drowsiness or poor feeding. Consult your doctor before breastfeeding.
💊 Overdose Management
Overdose of this medicine can cause severe neurological symptoms such as confusion, slurred speech, unsteady gait, nystagmus, and coma, as well as cardiac arrhythmias and low blood pressure. If overdose is suspected, seek emergency medical care immediately. Treatment is supportive and may include activated charcoal, airway management, and monitoring of heart rhythm and blood pressure. There is no specific antidote; hemodialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember if it is less than half the dosing interval away. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed, at the same time each day, with or without food, but be consistent. Swallow the extended-release tablet whole; do not crush, chew, or break it, because that can release the medicine too quickly and increase side effects. Do not stop this medicine suddenly on your own, as this can cause withdrawal seizures. Keep all follow-up appointments for blood tests that check the level of this medicine and monitor your liver, blood counts, and vitamin D. Tell your doctor about all other medicines, supplements, and herbal products you take, because many can interact with this medicine. Avoid alcohol, as it can increase drowsiness and affect seizure control. Use effective birth control if you are of childbearing age and discuss pregnancy plans with your doctor, because this medicine can harm an unborn baby. If you notice a rash, mouth sores, fever, yellowing of the eyes, or unusual bleeding, contact your doctor immediately. Do not drive or operate heavy machinery until you know how this medicine affects you.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the side effects of this medicine, especially drowsiness, dizziness, and unsteadiness. They may also have reduced liver function, requiring lower doses. Regular monitoring of blood levels and kidney function is important. Falls risk should be assessed.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor well in advance. This medicine can cause birth defects and cognitive problems in the baby. Your doctor may switch you to a safer alternative and recommend folic acid supplements. Do not stop this medicine suddenly, as seizures can harm both you and the baby.
🏥 Post-Surgery Considerations
After surgery, inform your surgeon and anesthesiologist that you take this medicine. It can interact with anesthetic agents and affect seizure control. Your dose may need adjustment during the perioperative period. Do not stop the medicine unless instructed by your doctor.
🦷 Dental Procedures
Inform your dentist that you take this medicine, as it can cause gum swelling and bleeding. Good oral hygiene is important. Your dentist may recommend more frequent cleanings. This medicine can also interact with some dental anesthetics and antibiotics, so always provide a complete medication list.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is generally safe and beneficial, but avoid activities where a sudden loss of awareness could be dangerous, such as swimming alone, climbing, or cycling on busy roads. Use appropriate safety gear. If you experience dizziness or unsteadiness, modify your exercise routine and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness or dizziness, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their usual work and daily activities once the dose is stabilized. Inform your employer about your condition if your job involves safety-sensitive tasks.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor may consider stopping it if you have been seizure-free for a long period and after a careful risk-benefit assessment. Stopping should be done gradually under medical supervision to avoid withdrawal seizures.
📅 Long-Term Use Effects
Long-term use of this medicine can cause gum swelling, increased hair growth, coarsening of facial features, bone thinning (osteoporosis), and peripheral neuropathy. Regular monitoring of blood levels, liver function, blood counts, and vitamin D levels is recommended. Your doctor may adjust the dose or consider alternative treatments if long-term side effects occur.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
A high-fat, low-carbohydrate diet that can help control seizures in some people, especially children, when medicines are not fully effective.
Evidence: Well-established for certain types of epilepsyA device implanted under the skin that sends electrical signals to the vagus nerve to reduce seizures.
Evidence: Established for drug-resistant epilepsySurgical removal of the brain area causing seizures, considered for some patients with drug-resistant epilepsy.
Evidence: Well-established in selected patients💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not generally interfere with vaccines. However, if you are scheduled for a live vaccine, inform your doctor. There is no specific contraindication to vaccination while taking this medicine, but always consult your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight and moisture
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep enough supply for your entire trip, plus extra in case of delays. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Carry a medical alert card stating you take this medicine for epilepsy. Check customs regulations for controlled medicines before traveling internationally.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within a few days, but it may take several weeks to achieve full seizure control. Your doctor will adjust the dose based on your response and blood levels.
A: No, do not stop this medicine suddenly, even if you feel better. Stopping abruptly can cause withdrawal seizures. Always consult your doctor before making any changes.
A: If you miss a dose, take it as soon as you remember if it is less than half the dosing interval away. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: This medicine can harm the unborn baby. If you are pregnant or planning pregnancy, discuss with your doctor about the risks and benefits, and whether an alternative treatment is suitable.
A: It is best to avoid alcohol while taking this medicine, as it can increase drowsiness and affect seizure control.
🤔 Common Patient Concerns
🔄 Substitutes for Stoin 150mg Tablet
View AllAlternative brands with exact same active ingredient:
-
Rapitoin 150mg InjectionEmcure Pharmaceuticals Ltd ₹30.94 78.3% COSTLIER
-
fosphen 150mg injectionIntas Pharmaceuticals Ltd ₹47.81 175.6% COSTLIER
-
fosolin 150mg injectionZydus Cadila ₹92.90 435.4% COSTLIER
-
epsolin 150mg tablet erZydus Cadila ₹192.00 1006.6% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure epilepsy.
Fact: This medicine controls seizures but does not cure epilepsy. It must be taken regularly to prevent seizures. - Myth: You can stop this medicine once seizures are controlled.
Fact: Stopping suddenly can cause withdrawal seizures. Always consult your doctor before stopping. - Myth: This medicine is safe to take with any other medicine.
Fact: This medicine interacts with many other medicines. Always inform your doctor about all medicines you take. - Myth: This medicine is safe during pregnancy.
Fact: This medicine can harm the unborn baby. Discuss with your doctor if you are pregnant or planning pregnancy.
🔄 Alternative Options
Generic Alternatives
- Phenytoin sodium extended-release tablets
Brand Alternatives
- Epsolin 150mg Tablet ER