StayHappi Trimetazidine 20mg Tablet - Trimetazidine (20mg) medicine

Angidine Tablet (Trimetazidine 20mg): Complete Medicine Guide

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🏭 Sarvagunaushdhi Pvt Ltd 📦 strip of 10 tablets 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for stable angina as add-on therapy.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • New or worsening tremors, rigidity, or difficulty walking
  • Severe dizziness or fainting
  • Chest pain that does not respond to your usual nitrate medicine
  • Signs of allergic reaction such as rash, swelling of face or throat, difficulty breathing
  • Unusual bruising or bleeding
  • Yellowing of skin or eyes, dark urine, or severe fatigue
  • Irregular or very fast heartbeat

If experiencing severe symptoms, call emergency services immediately.

What is StayHappi Trimetazidine 20mg Tablet used for?

This medicine contains Trimetazidine 20 mg, used as an add-on treatment for stable angina to reduce the frequency of chest pain attacks. It works by improving the heart's oxygen efficiency and is not for immediate relief of acute angina.

  • Generic Name: Trimetazidine (20mg)
  • Manufacturer: Sarvagunaushdhi Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 StayHappi Trimetazidine 20mg Tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ट्राइमेटाजिडीन 20 मिलीग्राम टैबलेट है, जिसका उपयोग स्थिर एंजाइना (सीने में दर्द) के इलाज में सहायक दवा के रूप में किया जाता है। यह दिल की मांसपेशियों को ऑक्सीजन का बेहतर उपयोग करने में मदद करती है, जिससे एंजाइना के दौरे कम होते हैं। यह दवा तुरंत दर्द में राहत के लिए नहीं है, बल्कि नियमित रूप से लेने पर दौरे रोकने में मदद करती है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, सिरदर्द, पेट में असहजता, जी मिचलाना और उल्टी शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। दुर्लभ मामलों में पार्किंसन जैसे लक्षण जैसे कंपन, अकड़न, धीमी चाल या संतुलन की समस्या हो सकती है। ऐसा होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। एंजाइना के तुरंत दौरे के लिए इसका उपयोग न करें; उसके लिए अपनी नाइट्रेट दवा पास रखें। अगर आपको किडनी या लीवर की समस्या है या कोई मूवमेंट डिसऑर्डर है तो डॉक्टर को बताएं। इस दवा के साथ शराब न लें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। दवा को ठंडी, सूखी जगह पर रखें और बच्चों से दूर रखें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 StayHappi Trimetazidine 20mg Tablet Uses & Benefits

[{"condition":"Stable angina pectoris","description":"Used as add-on therapy to reduce the frequency of angina attacks in adults whose symptoms are not adequately controlled by first-line anti-anginal medicines.","evidence":"Well-established"},{"condition":"Ischemic heart disease","description":"May be used to improve exercise tolerance and reduce ischemic episodes in patients with coronary artery disease.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Vertigo and tinnitus","description":"Sometimes prescribed off-label for dizziness and ringing in the ears, though evidence is limited.","evidence":"Limited"},{"condition":"Chorioretinal vascular disorders","description":"Occasionally used off-label for certain eye conditions involving blood flow, but not routinely recommended.","evidence":"Limited"}]

Primary treatment for: Stable angina pectoris

Also treats: Ischemic heart disease, Coronary artery disease

📋 Drug Information

Generic Name(s)Trimetazidine (20mg)
Brand NameStayHappi Trimetazidine 20mg Tablet
ManufacturerSarvagunaushdhi Pvt Ltd
Packaging / Formstrip of 10 tablets (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with meals to reduce stomach upset.
2
Do not use this medicine for immediate relief of an acute angina attack; keep fast-acting nitrates handy.
3
Inform your doctor if you have kidney problems, as dose adjustment may be needed.
4
Report any new movement symptoms such as tremors, rigidity, or difficulty walking immediately.
5
Avoid alcohol while taking this medicine to prevent dizziness and low blood pressure.
6
Do not stop this medicine suddenly without consulting your doctor.
7
Regular follow-up with your cardiologist is important to monitor your heart condition.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chest pain on exertion
This medicine is commonly prescribed for stable angina.
Likely Use
❌
Acute angina attack
This medicine is not for immediate relief; use fast-acting nitrates.
Not Primary
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is rapidly absorbed after oral administration. The bioavailability is high, and food does not significantly affect its absorption. Peak plasma levels are reached within 2 hours of taking a dose.
DistributionThis medicine is widely distributed in body tissues, including the heart, liver, and kidneys. It has a volume of distribution of approximately 4.8 L/kg. It crosses the blood-brain barrier to some extent.
Protein BindingPlasma protein binding of this medicine is low, approximately 16%.
MetabolismThis medicine is primarily metabolized in the liver, but the exact metabolic pathways are not fully established from the available information.
Half-LifeThe elimination half-life of this medicine is approximately 6 hours in healthy adults. It may be prolonged in elderly patients and those with kidney impairment.
ExcretionThis medicine and its metabolites are mainly excreted in the urine, with about 60-80% of an oral dose recovered in urine. A small amount is excreted in feces.
BioavailabilityThe oral bioavailability of this medicine is approximately 90% or higher.
Onset of ActionThe onset of action for this medicine is not immediate; it may take several days to weeks of regular use to notice a reduction in angina frequency.
Peak Plasma TimePeak plasma concentration is reached approximately 2 hours after oral administration.
Duration of ActionThe duration of action of this medicine is not precisely established, but its effects are sustained with regular twice or thrice daily dosing.

How It Works

This medicine works by inhibiting the enzyme long-chain 3-ketoacyl-CoA thiolase, which is involved in fatty acid oxidation in the heart muscle. By blocking this enzyme, it shifts the heart's energy production from fatty acids to glucose oxidation. This shift requires less oxygen to produce the same amount of energy, thereby improving the efficiency of oxygen use in the heart. As a result, the heart muscle can better withstand periods of reduced blood flow and oxygen supply, reducing the frequency of angina attacks. It also helps maintain proper cellular pH and reduces calcium overload in heart cells during ischemia.

Mechanism Steps

1
Inhibition of fatty acid oxidation: This medicine inhibits long-chain 3-ketoacyl-CoA thiolase, an enzyme involved in the beta-oxidation of fatty acids in the heart muscle.
2
Shift to glucose oxidation: By blocking fatty acid oxidation, the heart muscle shifts its energy production to glucose oxidation, which is more oxygen-efficient.
3
Improved oxygen efficiency: Glucose oxidation produces more ATP per molecule of oxygen consumed compared to fatty acid oxidation, improving the heart's energy supply during ischemia.
4
Cellular protection: This metabolic shift reduces the accumulation of harmful byproducts such as lactic acid and free radicals, protecting heart cells from ischemic damage.
5
Reduced angina frequency: As a result of improved energy metabolism and cellular protection, the heart experiences fewer ischemic episodes, leading to a reduction in angina attacks.

💡 How to Take StayHappi Trimetazidine 20mg Tablet

Strength: Trimetazidine 20 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a glass of water.
3You can take it with or without food, but taking it with meals may reduce stomach upset.
4Do not crush, chew, or break the tablet unless your doctor advises otherwise.
5Take it at the same times each day to maintain consistent levels in your body.
6Do not stop taking this medicine without consulting your doctor.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 20 mg taken two to three times daily, depending on the severity of angina and response to treatment. The dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose. This medicine is not for acute angina attacks.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced kidney function and may require dose adjustment. The dose must be individualized by a qualified clinician based on renal function and overall health.
Renal ImpairmentIn patients with moderate kidney impairment (creatinine clearance 30-60 mL/min), the dose may need to be reduced. This medicine is contraindicated in severe kidney impairment (creatinine clearance <30 mL/min). Dose must be individualized by a qualified clinician.
Hepatic ImpairmentNo specific dose adjustment is established for liver impairment. Use with caution and under medical supervision.
Maximum Daily DoseThe maximum recommended daily dose is 60 mg (20 mg three times daily).

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Grapefruit
Avoid excessive intake
May affect liver enzymes, though specific interaction is not well established.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of StayHappi Trimetazidine 20mg Tablet

✅ Common Side Effects

Dizziness (Common (1-10%))
Avoid driving or operating machinery until you know how it affects you. If dizziness persists, consult your doctor.
Headache (Common (1-10%))
Usually resolves on its own. If severe or persistent, consult your doctor.
Stomach discomfort (Common (1-10%))
Take with food to reduce stomach upset. If it continues, talk to your doctor.
Nausea (Common (1-10%))
Take with meals. If nausea is severe or persistent, consult your doctor.
Vomiting (Uncommon (0.1-1%))
Stay hydrated. If vomiting is severe or continues, seek medical advice.

🚨 Serious Side Effects

Parkinsonian symptoms (tremor, rigidity, slow movement, imbalance) (Rare (<0.1%))
Stop this medicine and contact your doctor immediately if you develop any of these symptoms.
Restless legs syndrome (Rare (<0.1%))
Report to your doctor if you experience an uncontrollable urge to move your legs, especially at rest.
Severe allergic reaction (rash, itching, swelling, difficulty breathing) (Very rare (<0.01%))
Seek emergency medical help immediately.
Low blood pressure (hypotension) (Uncommon (0.1-1%))
If you feel faint or dizzy, lie down and contact your doctor.
Palpitations (Uncommon (0.1-1%))
Report to your doctor if you notice irregular or fast heartbeat.

⚠️ Rare Side Effects

Agranulocytosis (severe drop in white blood cells)
Seek immediate medical attention if you develop fever, sore throat, or mouth ulcers.
Thrombocytopenia (low platelet count)
Report unusual bruising or bleeding to your doctor immediately.
Hepatitis (liver inflammation)
Seek medical advice if you notice yellowing of skin or eyes, dark urine, or severe fatigue.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Nitrates Moderate
Beta-blockers Moderate
Calcium channel blockers Moderate
Metoclopramide Moderate
Antipsychotics Moderate
Antacids Minor

🚨 Major Interactions

  • Other anti-anginal medicines (e.g., nitrates, beta-blockers, calcium channel blockers)

⚡ Moderate Interactions

  • Antihypertensive drugs
  • Drugs that can cause Parkinsonian symptoms (e.g., metoclopramide, antipsychotics)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness and low blood pressure while taking this medicine. It is advisable to avoid or limit alcohol consumption.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Parkinson's disease or Parkinsonian symptoms","Tremors, restless legs syndrome, or other movement disorders","Severe kidney impairment (creatinine clearance

⚠️ Warnings & Precautions

["This medicine is not for immediate relief of acute angina attacks. Keep fast-acting nitrates available.","May cause dizziness or drowsiness; avoid driving or operating machinery until you know how it affects you.","Use with caution in elderly patients and those with kidney or liver problems.","Inform your doctor if you have any movement disorders or a history of Parkinson's disease.","Do not stop taking this medicine abruptly without consulting your doctor.","Avoid alcohol while taking this medicine.","Regular follow-up is important to monitor your heart condition and kidney function."]

🤱 Lactation Safety

It is not known whether this medicine passes into breast milk. Consult your doctor before breastfeeding.

💊 Overdose Management

If you suspect an overdose, seek immediate medical attention. Symptoms of overdose may include severe dizziness, low blood pressure, palpitations, or fainting. Treatment is supportive and symptomatic. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without medical advice. This medicine is not for immediate relief of an acute angina attack; keep your fast-acting nitrate medicine handy for that purpose. Inform your doctor if you have kidney problems, liver problems, or any movement disorders. Avoid alcohol while taking this medicine as it may increase dizziness. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not share this medicine with others, even if they have similar symptoms. Store it in a cool, dry place away from direct sunlight and out of reach of children. Regular follow-up with your doctor is important to monitor your heart condition and adjust treatment if needed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and are more prone to dizziness and movement disorders. Dose adjustment may be needed based on kidney function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before taking this medicine. It should be used during pregnancy only if clearly needed and prescribed by a doctor.

🏥 Post-Surgery Considerations

Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may need to be stopped temporarily. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. No specific precautions are established, but it is important for your dentist to know your complete medication list.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce strain on your heart.
🥗
Engage in regular low-impact exercise such as walking or swimming, as advised by your doctor.
😴
Follow a heart-healthy diet low in saturated fats and rich in fruits and vegetables.
💧
Avoid smoking and limit alcohol consumption.
🧘
Manage stress through relaxation techniques like deep breathing or meditation.
🌞
Get adequate sleep and rest.
🚭
Take your medicines regularly and keep follow-up appointments.

🏋️ Exercise Considerations

Moderate exercise is beneficial for heart health, but avoid strenuous activities that trigger angina. Always warm up and cool down. If you experience chest pain, dizziness, or shortness of breath during exercise, stop and rest. Consult your doctor before starting any new exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like fish, flaxseeds, and walnuts.
Reduce intake of processed and fried foods.
Eat plenty of fruits, vegetables, and whole grains.
Limit salt and sugar intake.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It should not significantly impact your ability to work, but take precautions if you feel dizzy.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor. If you experience serious side effects such as Parkinsonian symptoms, severe dizziness, or allergic reactions, stop the medicine and seek medical advice immediately. Your doctor will decide if and when to discontinue.

📅 Long-Term Use Effects

Long-term use of this medicine is generally well tolerated. However, regular monitoring of kidney function and symptoms is recommended. Rarely, it may cause movement disorders, which usually resolve after stopping the medicine. Periodic review with your doctor is important to assess continued benefit and adjust treatment.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Lifestyle modifications

Heart-healthy diet, regular exercise, smoking cessation, and stress management can complement medicine for angina.

Evidence: Well-established
Other anti-anginal medicines

Beta-blockers, calcium channel blockers, nitrates, ranolazine, or ivabradine may be used depending on your condition.

Evidence: Well-established
Revascularization procedures

Angioplasty or bypass surgery may be considered for severe coronary artery disease.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. If traveling across time zones, continue taking it at the same intervals as prescribed; consult your doctor for specific advice. Store away from direct sunlight and moisture. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 58-year-old man with stable angina not fully controlled by beta-blockers
He was prescribed this medicine as an add-on. After 4 weeks, he noticed fewer angina attacks during his morning walks. He took it regularly with breakfast and dinner as advised. He reported mild dizziness initially, which resolved after a few days.
💡 Lesson: Consistent use and taking with food can improve tolerability and effectiveness.
👤 A 65-year-old woman with angina and mild kidney impairment
Her doctor adjusted the dose based on her kidney function. She was monitored regularly. She experienced no serious side effects and her angina frequency decreased. She was advised to avoid alcohol and to report any new symptoms.
💡 Lesson: Dose adjustment in kidney impairment and regular monitoring are important for safe use.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine may take several days to weeks of regular use to show its full effect in reducing angina frequency.

Q: Can I take this medicine with other heart medicines?

A: Yes, it is often prescribed as an add-on to other anti-anginal medicines. However, your doctor will monitor your blood pressure and adjust doses as needed.

Q: Is this medicine safe for long-term use?

A: It can be used long-term under medical supervision. Regular monitoring of kidney function and symptoms is advised.

Q: What should I do if I miss a dose?

A: Take it as soon as you remember if less than half the dosing interval has passed. Otherwise, skip it and continue with your regular schedule. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for StayHappi Trimetazidine 20mg Tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can be used to relieve an ongoing angina attack.
    Fact: This medicine is for prevention of angina attacks, not for immediate relief. Use fast-acting nitrates for acute attacks.
  • Myth: This medicine can be taken by anyone with chest pain.
    Fact: It is prescribed only for specific heart conditions and is contraindicated in certain movement disorders and severe kidney disease.
  • Myth: This medicine is a painkiller.
    Fact: It is not a painkiller; it works by improving heart metabolism and reducing angina frequency.

🔄 Alternative Options

Generic Alternatives

  • Trimetazidine 20 mg tablet

Brand Alternatives

  • Angidine 20 mg tablet
  • Trivedon 20 mg tablet
  • Flavedon 20 mg tablet
  • Metacard 20 mg tablet

📊 Comparison with Similar Medicines

[{"medicine":"Trimetazidine","class":"Anti-ischemic metabolic agent","main_use":"Add-on therapy for stable angina","effect_on_heart_rate":"No significant effect","effect_on_blood_pressure":"No significant effect"},{"medicine":"Ranolazine","class":"Anti-anginal","main_use":"Chronic angina","effect_on_heart_rate":"May slightly decrease","effect_on_blood_pressure":"May slightly decrease"},{"medicine":"Ivabradine","class":"Heart rate lowering agent","main_use":"Stable angina, heart failure","effect_on_heart_rate":"Decreases heart rate","effect_on_blood_pressure":"No significant effect"}]

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