stalia-plus tablet - Tranexamic Acid (500mg) + Tribasic Calcium Phosphate (144mg) medicine

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🏭 Wanbury Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for tranexamic acid in heavy menstrual bleeding; limited for the combination product.
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Sudden shortness of breath or chest pain
  • Swelling, pain, or redness in one leg
  • Severe headache with vision changes
  • Blood in urine or stool
  • Severe abdominal pain
  • Signs of allergic reaction (rash, swelling of face or throat, difficulty breathing)
  • Decreased urine output or painful urination

If experiencing severe symptoms, call emergency services immediately.

What is stalia-plus tablet used for?

This medicine is a combination of Tranexamic Acid and Tribasic Calcium Phosphate used to treat heavy menstrual bleeding. Tranexamic Acid reduces bleeding by preventing clot breakdown, while Tribasic Calcium Phosphate provides calcium and phosphate. It is taken orally, usually 1 tablet two to three times daily during menstruation, as prescribed by a doctor.

  • Generic Name: Tranexamic Acid (500mg) + Tribasic Calcium Phosphate (144mg)
  • Manufacturer: Wanbury Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 stalia-plus tablet के बारे में (Hindi Summary)

उपयोग: यह दवा ट्रैनेक्सैमिक एसिड और ट्राइबेसिक कैल्शियम फॉस्फेट का संयोजन है, जिसका उपयोग महिलाओं में अत्यधिक मासिक धर्म रक्तस्राव (मेनोरेजिया) के इलाज के लिए किया जाता है। यह रक्त के थक्के बनने में मदद करती है और रक्तस्राव को कम करती है। यह दवा कैल्शियम और फॉस्फेट भी प्रदान करती है, जो हड्डियों के स्वास्थ्य के लिए आवश्यक हैं। इसका उपयोग डॉक्टर की सलाह के बिना नहीं करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभावों में रक्त के थक्के बनना, एलर्जी प्रतिक्रिया, और गुर्दे की पथरी शामिल हो सकते हैं। यदि आपको पैर में सूजन, सीने में दर्द, या सांस लेने में कठिनाई हो, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक से अधिक न लें। यदि आपको रक्त के थक्के बनने की समस्या, गुर्दे की बीमारी, या कोई रक्तस्राव विकार है, तो डॉक्टर को बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर की सलाह के बिना न लें। पर्याप्त पानी पिएं। दवा को ठंडी, सूखी जगह पर रखें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 stalia-plus tablet Uses & Benefits

  • [{"condition":"Heavy menstrual bleeding (menorrhagia)","description":"This medicine is used to reduce excessive menstrual blood loss in women with regular cycles.
  • Tranexamic acid helps decrease bleeding by inhibiting clot breakdown, while calcium phosphate provides supportive minerals.","evidence":"Well-established"},{"condition":"Bleeding disorders","description":"It may be prescribed to manage bleeding in certain inherited or acquired bleeding disorders, such as von Willebrand disease or hemophilia, under specialist care.","evidence":"Established in specific cases"},{"condition":"Epistaxis (nosebleeds)","description":"Tranexamic acid in this combination can help control recurrent nosebleeds, though the calcium component is not directly involved in this effect.","evidence":"Limited"}]

Off-label uses: [{"condition":"Trauma-related bleeding","description":"Tranexamic acid has been studied for reducing bleeding in trauma patients, but this combination product is not specifically approved for that use.","evidence":"Limited"},{"condition":"Surgery prophylaxis","description":"Sometimes used off-label to reduce perioperative bleeding in certain surgeries, but the calcium phosphate component may not be necessary for this indication.","evidence":"Limited"}]

Primary treatment for: Heavy menstrual bleeding (menorrhagia)

Also treats: Bleeding disorders, Epistaxis

📋 Drug Information

Generic Name(s)Tranexamic Acid (500mg) + Tribasic Calcium Phosphate (144mg)
Brand Namestalia-plus tablet
ManufacturerWanbury Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineTranexamic acid is included in the WHO Model List of Essential Medicines for the treatment of heavy menstrual bleeding and bleeding in trauma. However, the combination with tribasic calcium phosphate is not specifically mentioned in WHO guidelines.
ICMR GuidelineThe Indian Council of Medical Research (ICMR) does not have specific guidelines for this combination product. Tranexamic acid is recognized for use in heavy menstrual bleeding as per standard gynecological practice in India.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce the risk of stomach upset.
2
Do not exceed the prescribed dose or duration, as it may increase the risk of blood clots.
3
Stay well hydrated throughout the day to support kidney function.
4
Avoid alcohol while taking this medicine to prevent gastrointestinal bleeding.
5
Inform your doctor if you have a history of blood clots, heart attack, or stroke before taking this medicine.
6
Report any unusual bleeding, bruising, or signs of a blood clot immediately.
7
Do not use this medicine for more than 5 days without consulting your doctor.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Heavy menstrual bleeding
This medicine is commonly prescribed for this condition.
Likely Use
✅
Nosebleeds
May be used to control recurrent nosebleeds.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary
❌
Joint pain
This medicine is not primarily used for joint pain.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionTranexamic Acid is rapidly absorbed from the gastrointestinal tract after oral administration, with peak plasma concentrations reached in about 2 to 3 hours. The absorption of Tribasic Calcium Phosphate depends on gastric acid solubility and is enhanced in the presence of food.
DistributionTranexamic Acid distributes widely into body tissues and fluids, including synovial fluid, aqueous humor, and breast milk. It crosses the placenta. The volume of distribution is approximately 9 to 12 liters. Calcium and phosphate ions distribute throughout the body, with calcium primarily stored in bones.
Protein BindingTranexamic Acid binds minimally to plasma proteins (approximately 3%). Calcium and phosphate ions are not significantly protein-bound.
MetabolismTranexamic Acid is not metabolized to any significant extent. Tribasic Calcium Phosphate is broken down into calcium and phosphate ions, which are not metabolized.
Half-LifeThe elimination half-life of Tranexamic Acid is approximately 2 to 3 hours in patients with normal renal function. The half-life may be prolonged in patients with renal impairment. Calcium and phosphate are eliminated via renal and fecal routes.
ExcretionTranexamic Acid is excreted primarily unchanged in the urine (approximately 95% of an administered dose). Calcium and phosphate are excreted mainly in the urine and feces, with renal excretion being the primary route for calcium homeostasis.
BioavailabilityThe oral bioavailability of Tranexamic Acid is approximately 30% to 50%. The bioavailability of calcium from Tribasic Calcium Phosphate is variable and depends on factors such as gastric acidity and presence of food.
Onset of ActionThe antifibrinolytic effect of Tranexamic Acid begins within 1 to 2 hours after oral administration. The calcium supplementation effect is gradual and not immediately noticeable.
Peak Plasma TimePeak plasma concentration of Tranexamic Acid is reached approximately 2 to 3 hours after oral intake. Calcium absorption peaks within 1 to 2 hours after ingestion.
Duration of ActionThe antifibrinolytic effect of Tranexamic Acid lasts approximately 6 to 8 hours after a single oral dose. The effect on calcium levels is longer-lasting but depends on ongoing supplementation.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Tranexamic Acid is a synthetic lysine analog that reversibly binds to plasminogen and plasmin, blocking their interaction with fibrin. This inhibits fibrinolysis, thereby stabilizing blood clots and reducing bleeding. Tribasic Calcium Phosphate serves as a source of calcium and phosphate ions, which are essential for bone mineralization and various metabolic functions. The combination does not have a synergistic mechanism for bleeding control; the calcium component is primarily nutritional.

Mechanism Steps

1
Binding to plasminogen: Tranexamic Acid binds reversibly to the lysine-binding sites on plasminogen, preventing its activation to plasmin.
2
Inhibition of fibrinolysis: By blocking plasminogen activation, Tranexamic Acid reduces the degradation of fibrin clots, thereby stabilizing them and reducing bleeding.
3
Calcium and phosphate supplementation: Tribasic Calcium Phosphate dissociates into calcium and phosphate ions, which are absorbed and used for various physiological processes, including bone mineralization.

💡 How to Take stalia-plus tablet

Strength: Each tablet contains Tranexamic Acid 500mg and Tribasic Calcium Phosphate 144mg.

1Take the tablet orally with a full glass of water.
2Swallow the tablet whole; do not crush or chew.
3Take with food to reduce stomach upset.
4Follow the prescribed schedule and duration.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose for heavy menstrual bleeding is 1 tablet (Tranexamic Acid 500mg + Tribasic Calcium Phosphate 144mg) two to three times daily, depending on the severity of bleeding. For other bleeding disorders, the dose may vary. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the prescribed dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may have reduced renal function and are at higher risk of side effects. Dose adjustment may be necessary based on renal function. Consult a doctor for appropriate dosing.
Renal ImpairmentIn patients with renal impairment, dose reduction is recommended. For creatinine clearance 30-60 mL/min, the dose may be reduced to 1 tablet twice daily. For creatinine clearance <30 mL/min, the dose may be reduced to 1 tablet once daily or as directed by a nephrologist.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment. Use with caution and under medical supervision.
Maximum Daily DoseThe maximum recommended daily dose is 3 tablets (Tranexamic Acid 1500mg + Tribasic Calcium Phosphate 432mg) per day, unless otherwise directed by a doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and enhances calcium absorption.
Spinach, rhubarb, whole grains
Separate by 2 hours
These foods contain oxalates and phytates that can bind calcium and reduce its absorption.
Caffeine
Limit excessive intake
Caffeine may increase calcium excretion.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of stalia-plus tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated and take with meals. Consult doctor if severe.
Diarrhea (Common (5-10%))
Increase fluid intake. If diarrhea is severe or persistent, seek medical advice.
Stomach pain (Common (5-10%))
Take with food. If pain is severe, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. Consult doctor if headache is severe or persistent.

🚨 Serious Side Effects

Blood clots (thrombosis) (Rare (<0.1%))
Seek immediate medical attention if you experience leg swelling, pain, chest pain, or shortness of breath.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you have difficulty breathing, swelling of face or throat, or severe rash.
Kidney stones (Rare (<0.1%))
Report severe back or flank pain, blood in urine, or painful urination to your doctor.
Visual disturbances (Rare (<0.1%))
If you notice changes in vision, stop the medicine and consult an ophthalmologist immediately.

⚠️ Rare Side Effects

Seizures
Seek emergency medical care if seizures occur.
Hypotension
If you feel dizzy or faint, lie down and seek medical help.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Heparin Major
Aspirin Major
Clopidogrel Major
Tretinoin (oral) Major
Alteplase Moderate
Thiazide diuretics Moderate
Calcium supplements Moderate
Antacids (Al/Mg) Minor
Iron supplements Minor

🚨 Major Interactions

  • Anticoagulants (e.g., warfarin, heparin)
  • Antiplatelet agents (e.g., aspirin, clopidogrel)
  • Tretinoin (oral)

⚡ Moderate Interactions

  • Thrombolytic agents (e.g., alteplase)
  • Calcium supplements
  • Thiazide diuretics

🍷 Alcohol Interaction

Alcohol may increase the risk of gastrointestinal bleeding and can exacerbate the side effects of this medicine. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Active thromboembolic disease (e.g., deep vein thrombosis, pulmonary embolism)","History of arterial thrombosis (e.g., myocardial infarction, stroke)","Severe renal impairment (creatinine clearance

⚠️ Warnings & Precautions

["Use with caution in patients with a history of blood clots or cardiovascular disease.","Avoid in patients with severe kidney disease; dose adjustment may be needed.","Do not use for more than 5 days without medical advice.","May cause visual disturbances; avoid driving if affected.","Concurrent use with anticoagulants requires close monitoring.","Not recommended for use in pregnancy unless clearly needed.","Calcium phosphate may increase risk of kidney stones with prolonged use."]

🤱 Lactation Safety

Tranexamic acid is excreted in breast milk at low concentrations. It is generally considered safe for short-term use during breastfeeding, but consult your doctor before use. Calcium phosphate is a normal component of breast milk and is safe.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and increased risk of thrombosis. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases with renal impairment.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Inform your doctor if you have a history of blood clots, kidney disease, or any bleeding disorder. Avoid using this medicine if you are pregnant or breastfeeding unless specifically advised by your doctor. Do not take this medicine with other medications that affect blood clotting, such as anticoagulants or antiplatelet drugs, without consulting your doctor. Maintain adequate hydration while taking this medicine. Store it in a cool, dry place away from direct sunlight and out of reach of children. If you experience any signs of a blood clot, such as leg pain, swelling, or difficulty breathing, seek emergency medical help immediately.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and are at higher risk of side effects such as blood clots and kidney stones. Dose adjustment may be necessary based on renal function. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. Tranexamic acid may not be suitable during pregnancy. Your doctor may recommend alternative treatments for heavy menstrual bleeding if you are trying to conceive.

🏥 Post-Surgery Considerations

This medicine may be prescribed after certain surgeries to reduce bleeding. Follow your surgeon's instructions carefully. Inform your surgeon if you have a history of blood clots or are taking anticoagulants.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may affect bleeding during dental work. Your dentist may recommend temporary discontinuation or alternative measures.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce the burden on your menstrual health.
🥗
Stay physically active with moderate exercise to improve circulation.
😴
Stay well hydrated to support kidney function and prevent stones.
💧
Include calcium-rich foods in your diet, but avoid excessive supplementation.
🧘
Get adequate rest during your menstrual period.
🌞
Practice stress-reducing techniques like yoga or meditation.

🏋️ Exercise Considerations

Moderate exercise is generally safe while taking this medicine. However, if you experience dizziness or visual disturbances, avoid strenuous activities or driving. Consult your doctor before starting any new exercise regimen.

🥗 Diet Recommendations

Include calcium-rich foods like dairy, leafy greens, and fortified cereals.
Avoid excessive caffeine and alcohol.
Stay well hydrated by drinking plenty of water.
Limit foods high in oxalates (spinach, rhubarb) if you are prone to kidney stones.
Eat a balanced diet rich in iron to prevent anemia from heavy bleeding.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or visual disturbances in some people, which can affect your ability to drive or operate machinery. If you experience these effects, avoid such activities until you feel normal. Otherwise, it generally does not interfere with daily work life.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience any signs of a blood clot, severe allergic reaction, or visual disturbances. Do not stop abruptly without consulting your doctor if you are taking it for a bleeding disorder. Always consult your doctor before stopping this medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of kidney stones due to the calcium phosphate component. Prolonged use of Tranexamic Acid may also increase the risk of thrombosis. Regular monitoring of kidney function and signs of blood clots is advised. This medicine is generally not recommended for long-term use without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Hormonal therapy

Birth control pills or hormonal IUDs can reduce heavy menstrual bleeding.

Evidence: Well-established
Nonsteroidal anti-inflammatory drugs (NSAIDs)

NSAIDs like ibuprofen can reduce menstrual bleeding and pain.

Evidence: Well-established
Surgical options

Endometrial ablation or hysterectomy may be considered for severe cases.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. You can receive vaccinations as scheduled. However, consult your doctor if you have any concerns.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from direct sunlight and moisture. If crossing time zones, continue taking the medicine as prescribed; no specific time zone adjustment is needed for this medicine. Check local customs regulations regarding prescription medications before traveling internationally.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 38-year-old woman with heavy menstrual bleeding
She was prescribed this medicine for 5 days during her periods. She noticed a significant reduction in bleeding within the first two days. She took it with food to avoid nausea and stayed hydrated. She was advised not to take it for more than 5 days.
💡 Lesson: Taking the medicine with food and adhering to the prescribed duration helps manage heavy bleeding effectively while minimizing side effects.
👤 A 45-year-old woman with a history of blood clots
She was prescribed this medicine for heavy bleeding but forgot to inform her doctor about her previous deep vein thrombosis. After two days, she developed leg swelling and pain. She sought immediate medical help and was diagnosed with a blood clot. The medicine was stopped, and she was treated with anticoagulants.
💡 Lesson: Always inform your doctor about your complete medical history, especially any history of blood clots, before taking this medicine.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts reducing bleeding within 1 to 2 hours after taking a dose. However, the full effect may take a day or two.

Q: Can I take this medicine with food?

A: Yes, taking it with food is recommended to reduce stomach upset and improve calcium absorption.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is it safe to take this medicine during pregnancy?

A: This medicine is not recommended during pregnancy unless clearly needed and prescribed by your doctor. Consult your healthcare provider before use.

Q: Can this medicine cause blood clots?

A: Yes, Tranexamic Acid can increase the risk of blood clots, especially in people with a history of clotting disorders. Report any signs of clots immediately.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Does it cause weight gain?

🔄 Substitutes for stalia-plus tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Pause-xt tablet is a contraceptive.
    Fact: This medicine does not prevent pregnancy. It only reduces heavy bleeding.
  • Myth: Pause-xt tablet can be taken for any bleeding.
    Fact: It is specifically for heavy menstrual bleeding and certain bleeding disorders. It should not be used for minor cuts or bruises.
  • Myth: Pause-xt tablet is safe to take without a prescription.
    Fact: It is a prescription medicine and should only be taken under medical supervision due to the risk of blood clots.

🔄 Alternative Options

Generic Alternatives

  • Tranexamic Acid 500mg + Calcium Phosphate 144mg tablet (various manufacturers)

Brand Alternatives

  • Pause-xt tablet (Emcure Pharmaceuticals Ltd)

📊 Comparison with Similar Medicines

[{"medicine":"Tranexamic Acid alone","composition":"Tranexamic Acid 500mg","uses":"Heavy menstrual bleeding, bleeding disorders","key_difference":"Does not contain calcium phosphate."},{"medicine":"Tranexamic Acid + Mefenamic Acid","composition":"Tranexamic Acid 500mg + Mefenamic Acid 250mg","uses":"Heavy menstrual bleeding with pain","key_difference":"Contains an NSAID for pain relief."},{"medicine":"Tranexamic Acid + Ethamsylate","composition":"Tranexamic Acid 500mg + Ethamsylate 250mg","uses":"Heavy menstrual bleeding","key_difference":"Contains ethamsylate, another hemostatic agent."}]

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