Axamic 500mg Injection - Uses, Price, Side Effects
What is axamic 500mg injection used for?
Axamic 500mg Injection contains Tranexamic Acid, an antifibrinolytic agent that prevents bleeding by blocking the breakdown of blood clots. It is used for conditions like heavy menstrual bleeding, nosebleeds, and bleeding after surgery or trauma.
- Generic Name: Tranexamic Acid
- Manufacturer: Axis Life Science Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ axamic 500mg injection Uses & Benefits
Menorrhagia, epistaxis, hemoptysis, gastrointestinal bleeding, hemophilia (adjunct), dental procedures in hemophiliacs, traumatic hyphema, hereditary angioedema.
Off-label uses: Cardiac surgery, orthopedic surgery, trauma, postpartum hemorrhage.
๐ Drug Information
| Generic Name(s) | Tranexamic Acid |
| Brand Name | Armril Injection IP |
| Manufacturer | Axis Life Science Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Antifibrinolytic |
| Route of Administration | Intravenous (IV) injection or infusion. |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Competitively inhibits plasminogen activation and plasmin activity, thereby reducing fibrinolysis and stabilizing clots.
Mechanism Steps
๐ก How to Take axamic 500mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of axamic 500mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Dizziness
- Headache
- Hypotension (with rapid IV injection)
๐จ Serious Side Effects
- Thromboembolic events (DVT, PE, stroke)
- Acute renal cortical necrosis
- Seizures
- Anaphylaxis
- Visual disturbances
โ ๏ธ Rare Side Effects
- Color vision disturbances
- Retinal artery occlusion
- Hypersensitivity reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Oral Contraceptives | Moderate | Increased risk of thrombosis |
| Factor IX Complex Concentrates | Major | Increased risk of thrombosis |
| Tretinoin | Moderate | Increased risk of thrombosis |
| Chlorpromazine | Minor | Decreased efficacy of tranexamic acid |
๐จ Major Interactions
- Warfarin
- Heparin
- Low molecular weight heparins
- Direct oral anticoagulants (DOACs)
- Thrombolytics (e.g., alteplase)
โก Moderate Interactions
- Aspirin
- NSAIDs
- Clopidogrel
- Antiplatelet agents
- Estrogens
- Oral contraceptives
โน๏ธ Minor Interactions
- Corticosteroids
- Tetracyclines
- Penicillins
๐ฝ๏ธ Food Interactions
No significant food interactions.
๐ท Alcohol Interaction
No known interaction.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to tranexamic acid; active intravascular clotting; history of thromboembolic disease; subarachnoid hemorrhage; severe renal impairment.
๐ Monitoring Parameters
Renal function, signs of thrombosis, bleeding control.
๐คฑ Lactation Safety
Excreted in breast milk; use with caution.
๐ Overdose Management
No specific antidote; supportive care; consider hemodialysis if severe.
โฐ Missed Dose
Not applicable for single-dose or intermittent IV use; follow prescribed schedule.
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for axamic 500mg injection
View AllAlternative brands with exact same active ingredient (Tranexamic Acid (500mg)):
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Tranomac 500mg InjectionMacleods Pharmaceuticals Pvt Ltd โน32.06 111.2% COSTLIER
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vtramic 500mg injectionBiovista Lifesciences โน34.00 124% COSTLIER
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dubatran 500mg injectionAlembic Pharmaceuticals Ltd โน39.47 160% COSTLIER
Medical Note: Always consult your doctor before switching medications.
โญ User Reviews
Found this to be a helpful product. Good results.
Good quality medicine. Satisfied with the outcome.
This medicine was effective for me. I followed the doctor's advice.
This medicine was effective for me. I followed the doctor's advice.
Effective and reliable. Worked as expected.