Anadecon Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Fast or irregular heartbeat
- Hallucinations or seizures
If experiencing severe symptoms, call emergency services immediately.
What is Smace Tablet used for?
This medicine is a combination of Caffeine (15 mg) and Chlorpheniramine Maleate (2 mg) used to treat allergic rhinitis and common cold symptoms. Chlorpheniramine is an antihistamine that relieves sneezing, runny nose, and itchy eyes, while Caffeine helps reduce drowsiness caused by the antihistamine. It is taken orally every 4-6 hours as needed, up to 6 tablets daily. Avoid alcohol and driving due to drowsiness.
- Generic Name: Caffeine (15mg) + Chlorpheniramine Maleate (2mg)
- Manufacturer: Smiles Healthcare
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Smace Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा कैफीन (15 मिलीग्राम) और क्लोरफेनिरामाइन मेलिएट (2 मिलीग्राम) का संयोजन है। इसका उपयोग एलर्जी राइनाइटिस, सर्दी-जुकाम और अन्य ऊपरी श्वसन एलर्जी के लक्षणों जैसे छींक, बहती नाक, खुजली वाली आंखों और नाक की भीड़ को कम करने के लिए किया जाता है। क्लोरफेनिरामाइन हिस्टामिन को ब्लॉक करता है जिससे एलर्जी के लक्षण कम होते हैं, जबकि कैफीन नींद को कम करने में मदद करता है। यह दवा मुंह से ली जाती है और डॉक्टर के निर्देशानुसार लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, चक्कर आना, मुंह सूखना, धुंधली दृष्टि, मतली और बेचैनी शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज दिल की धड़कन, दौरे, या गंभीर एलर्जी प्रतिक्रिया शामिल हो सकती है। यदि कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को बताएं यदि आपको ग्लूकोमा, प्रोस्टेट की समस्या, अस्थमा, हृदय रोग, उच्च रक्तचाप, या लीवर/किडनी की बीमारी है। यह दवा नींद का कारण बन सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें। शराब का सेवन न करें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। बच्चों को डॉक्टर की सलाह के बिना न दें।
💊 Smace Tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from runny nose, sneezing, and watery eyes due to colds, while caffeine helps reduce associated fatigue.","evidence":"Well-established"},{"condition":"Urticaria","description":"Helps reduce itching and hives due to allergic reactions, though caffeine may not directly affect urticaria.","evidence":"Moderate"},{"condition":"Vasomotor rhinitis","description":"May alleviate non-allergic rhinitis symptoms such as runny nose and sneezing.","evidence":"Limited"}]
Off-label uses: [{"condition":"Motion sickness","description":"Sometimes used off-label for motion sickness due to antihistamine effects, but not a primary indication.","evidence":"Limited"},{"condition":"Insomnia due to shift work","description":"Caffeine component may be used off-label to promote wakefulness, but chlorpheniramine counteracts this; not recommended.","evidence":"Insufficient"}]
Primary treatment for: Allergic rhinitis
Also treats: Common cold, Urticaria, Vasomotor rhinitis
📋 Drug Information
| Generic Name(s) | Caffeine (15mg) + Chlorpheniramine Maleate (2mg) |
| Brand Name | Smace Tablet |
| Manufacturer | Smiles Healthcare |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Chlorpheniramine Maleate is a first-generation antihistamine that competitively blocks histamine H1 receptors, thereby preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation. Caffeine is a central nervous system stimulant that acts as an adenosine receptor antagonist, which increases neuronal activity and releases neurotransmitters like dopamine and norepinephrine, leading to increased alertness and reduced fatigue. The combination aims to provide allergy relief while mitigating the sedative effects of the antihistamine.
Mechanism Steps
💡 How to Take Smace Tablet
Strength: Each tablet contains Caffeine 15 mg and Chlorpheniramine Maleate 2 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1 tablet taken orally every 4 to 6 hours as needed for symptoms, not to exceed 6 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and response to treatment. Do not self-adjust the dose. Follow your doctor's instructions carefully. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients (above 65 years) are more sensitive to the anticholinergic and sedative effects of chlorpheniramine and the stimulant effects of caffeine. Lower doses may be appropriate. Dose must be individualized by a qualified clinician based on renal and hepatic function and overall health status. |
| Renal Impairment | In patients with renal impairment, chlorpheniramine and caffeine clearance may be reduced. Dose adjustment may be necessary. Consult a clinician for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, metabolism of both chlorpheniramine and caffeine may be reduced, increasing the risk of side effects. Dose reduction may be required. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose for adults is 6 tablets in 24 hours. Do not exceed this dose unless directed by a doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Smace Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Alcohol | Major | |
| Benzodiazepines | Major | |
| Fluoxetine | Moderate | |
| Ciprofloxacin | Moderate | |
| Tricyclic antidepressants | Moderate | |
| Rifampin | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Alcohol
- Other CNS depressants (e.g., benzodiazepines, opioids, sleep aids)
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- CYP1A2 inhibitors (e.g., ciprofloxacin, fluvoxamine)
- Anticholinergic drugs (e.g., atropine, benztropine, tricyclic antidepressants)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine because it can significantly increase drowsiness, dizziness, and impairment of motor skills. The combination can also increase the risk of respiratory depression. Do not drive or operate machinery if you have consumed alcohol.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to chlorpheniramine, caffeine, or any component of the formulation","Narrow-angle glaucoma","Urinary retention or prostatic hypertrophy","Severe liver disease","Concurrent use with monoamine oxidase inhibitors (MAOIs)","Children under 12 years of age (unless directed by a doctor)"]
⚠️ Warnings & Precautions
["May cause drowsiness; avoid driving or operating machinery.","Avoid alcohol and other CNS depressants.","Use with caution in patients with asthma, heart disease, hypertension, thyroid disorders, or diabetes.","May cause dry mouth, eyes, and nose; maintain hydration.","Do not exceed recommended dose; overdose can be dangerous.","Consult doctor if symptoms persist beyond 7 days or are accompanied by fever.","Elderly patients are more sensitive to anticholinergic and sedative effects.","Not recommended for children under 12 years without medical advice."]
🤱 Lactation Safety
Chlorpheniramine Maleate and Caffeine are excreted in breast milk. Chlorpheniramine may cause drowsiness in the nursing infant. Caffeine may cause irritability or poor sleep. Breastfeeding mothers should consult their doctor before using this medicine.
💊 Overdose Management
Overdose symptoms may include severe drowsiness, confusion, hallucinations, seizures, irregular heartbeat, and difficulty breathing. If overdose is suspected, seek emergency medical attention immediately. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if within 1-2 hours of ingestion. Monitor vital signs and provide supportive care.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you have glaucoma, an enlarged prostate, difficulty urinating, asthma, heart disease, high blood pressure, thyroid problems, or liver or kidney disease. This medicine can cause drowsiness; avoid driving, operating heavy machinery, or performing activities requiring alertness until you know how it affects you. Do not drink alcohol while taking this medicine, as it can increase drowsiness and dizziness. Avoid taking other medications that cause drowsiness, such as sedatives, tranquilizers, or sleeping pills, without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using this medicine. Do not use this medicine for longer than prescribed without medical advice. Keep out of reach of children. In case of overdose, seek emergency medical help immediately, even if you feel fine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the anticholinergic and sedative effects of chlorpheniramine and the stimulant effects of caffeine. They may experience increased confusion, dizziness, or urinary retention. Lower doses may be appropriate. Consult a doctor for individualized dosing.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Chlorpheniramine is considered relatively safe in pregnancy (Category B), but caffeine should be limited. Use only if clearly needed and under medical supervision.
🏥 Post-Surgery Considerations
After surgery, use this medicine with caution as it may interact with anesthetics and other medications. Inform your surgeon and anesthesiologist about all medications you are taking. It may increase the risk of drowsiness and respiratory depression.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth, which can affect dental health. Also, it may interact with sedatives used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness, which can affect your coordination. Avoid strenuous exercise or activities requiring alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, which may impair your ability to drive or operate machinery. It is advisable to avoid such activities until you know how it affects you. It may also affect your concentration and productivity. Plan your tasks accordingly.
🛑 When to Stop This Medicine
Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to tolerance to the stimulant effects of caffeine and increased sedation from chlorpheniramine. It may also cause dependence on the sedative effects. Regular monitoring of liver and kidney function may be advised if used for extended periods. Consult your doctor for periodic review.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve nasal congestion without medication.
Evidence: Well-establishedReducing exposure to allergens can decrease symptoms.
Evidence: Well-establishedNon-sedating antihistamines like loratadine or cetirizine may be alternatives.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No known interactions with vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it in a cool, dry place away from direct sunlight. If crossing time zones, adjust dosing according to your doctor's advice. Check customs regulations for carrying medications. Keep it in your carry-on luggage to avoid loss.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts working within 30 to 60 minutes after taking it.
A: Yes, but it may cause drowsiness. Many people take it at bedtime to help with sleep while relieving allergy symptoms.
A: This medicine is not recommended for children under 12 years without a doctor's advice.
A: Consult your doctor before combining with other antihistamines or cold medicines to avoid additive effects.
🤔 Common Patient Concerns
🔄 Substitutes for Smace Tablet
View AllAlternative brands with exact same active ingredient:
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descold tabletSymet Drugs Ltd ₹10.31 58.8% CHEAPER
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osolate tabletOsho Pharma Pvt Ltd ₹10.31 58.8% CHEAPER
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kuffery cold tabletZeelab Pharmacy Pvt Ltd ₹11.00 56% CHEAPER
-
cosil forte tabletAlpha Drugs & Pharmaceuticals ₹11.25 55% CHEAPER
-
harilate tabletPramukh Swami Pharma Ltd ₹13.13 47.5% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a cure for the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take more than the recommended dose if symptoms are severe.
Fact: Taking more than the recommended dose can lead to serious side effects and overdose. Always follow the prescribed dose. - Myth: This medicine is non-drowsy.
Fact: Chlorpheniramine is a sedating antihistamine; although caffeine may counteract some drowsiness, it can still cause significant sedation.
🔄 Alternative Options
Generic Alternatives
- Caffeine + Chlorpheniramine Maleate tablets from other manufacturers
Brand Alternatives
- Anadecon Tablet