Fexagon Plus 60mg/10mg/325mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Blood in stool or vomit
- Severe abdominal pain
- Chest pain or difficulty breathing
- Severe headache with visual changes
- Sudden swelling of face, lips, or throat
- Yellowing of skin or eyes
- Decreased urine output
- Rapid or irregular heartbeat
If experiencing severe symptoms, call emergency services immediately.
What is sinarest fxp tablet used for?
This medicine is a combination of fexofenadine (antihistamine), phenylephrine (decongestant), and paracetamol (analgesic/antipyretic) used for short-term relief of allergic rhinitis and common cold symptoms. It reduces sneezing, runny nose, nasal congestion, and mild pain or fever. It should not be used by people with severe hypertension or those taking MAOIs.
- Generic Name: Fexofenadine (60mg) + Phenylephrine (10mg)
- Manufacturer: Centaur Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sinarest fxp tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एलर्जी और सर्दी-जुकाम के लक्षणों जैसे नाक बंद होना, छींक आना, नाक बहना, आंखों में खुजली और हल्के दर्द या बुखार को कम करने के लिए इस्तेमाल की जाती है। इसमें फेक्सोफेनाडीन, फेनाइलएफ्रिन और पैरासिटामोल होते हैं। यह अल्पकालिक उपयोग के लिए है और डॉक्टर की सलाह के बिना 7 दिनों से अधिक नहीं लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, सिरदर्द, जी मिचलाना और बेचैनी शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज धड़कन, रक्तचाप बढ़ना, गंभीर चक्कर आना और एलर्जी प्रतिक्रिया हो सकती है। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा की अनुशंसित खुराक से अधिक न लें। नींद आने पर वाहन चलाने या मशीनरी चलाने से बचें। पैरासिटामोल या फेनाइलएफ्रिन युक्त अन्य दवाओं के साथ न लें। शराब का सेवन न करें। यदि आपको उच्च रक्तचाप, हृदय रोग, मधुमेह, थायरॉइड या गुर्दे/यकृत की समस्या है तो डॉक्टर को बताएं। 7 दिनों से अधिक उपयोग न करें।
💊 sinarest fxp tablet Uses & Benefits
[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from nasal congestion, sneezing, and mild pain or fever associated with the common cold.","evidence":"Well-established"},{"condition":"Sinusitis","description":"Helps reduce nasal congestion and pressure in sinusitis, though it does not treat the underlying infection.","evidence":"Supportive"}]
Off-label uses: []
Primary treatment for: Allergic rhinitis and common cold
Also treats: Sinusitis, Nasal congestion, Sneezing, Mild pain and fever
📋 Drug Information
| Generic Name(s) | Fexofenadine (60mg) + Phenylephrine (10mg) |
| Brand Name | sinarest fxp tablet |
| Manufacturer | Centaur Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines three active ingredients with complementary actions. Fexofenadine selectively blocks peripheral histamine H1 receptors, reducing allergic symptoms. Phenylephrine stimulates alpha-1 adrenergic receptors, causing vasoconstriction in nasal mucosa and reducing congestion. Paracetamol acts centrally to relieve pain and fever, though its exact mechanism is not fully understood.
Mechanism Steps
💡 How to Take sinarest fxp tablet
Strength: Each tablet contains fexofenadine 60 mg, phenylephrine 10 mg, and paracetamol 325 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally every 8 to 12 hours as needed for symptoms, not to exceed 3 tablets in 24 hours. However, the exact dose and frequency must be individualized by a qualified clinician based on the indication, age, weight, renal and hepatic function, and other medications being taken. Do not self-medicate; follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of phenylephrine and fexofenadine. Use with caution and lower doses may be appropriate. Consult a doctor for individualized dosing. |
| Renal Impairment | Dose adjustment may be needed in patients with renal impairment. Consult a doctor for individualized dosing. |
| Hepatic Impairment | Dose adjustment may be needed in patients with hepatic impairment. Paracetamol should be used with caution. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose is 3 tablets in 24 hours. Do not exceed this limit. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sinarest fxp tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| Beta-blockers | Major | |
| Tricyclic antidepressants | Major | |
| Warfarin | Moderate | |
| Alcohol | Moderate | |
| Digoxin | Moderate | |
| Ergot alkaloids | Moderate | |
| Antacids | Minor | |
| Fruit juices | Minor | |
| Other sedatives | Moderate |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Beta-blockers
- Tricyclic antidepressants
- Warfarin
⚡ Moderate Interactions
- Other antihistamines, alcohol, sedatives
- Digoxin
- Ergot alkaloids
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness caused by fexofenadine and increase the risk of liver damage from paracetamol. It may also worsen the cardiovascular effects of phenylephrine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to any component","Severe hypertension or coronary artery disease","Use within 14 days of MAOI therapy","Severe liver disease","Pheochromocytoma","Hyperthyroidism"]
⚠️ Warnings & Precautions
["Do not exceed recommended dose.","Avoid alcohol.","May cause drowsiness; avoid driving.","Caution in patients with cardiovascular disease, diabetes, thyroid disorders, or glaucoma.","Do not use for more than 7 days without medical advice.","Keep out of reach of children."]
🤱 Lactation Safety
Not established from the available information. Fexofenadine may pass into breast milk in small amounts. Phenylephrine may reduce milk production. Consult your doctor before use while breastfeeding.
💊 Overdose Management
Overdose can cause severe liver damage from paracetamol, hypertensive crisis from phenylephrine, and severe drowsiness from fexofenadine. Seek immediate medical attention. Treatment includes gastric lavage, activated charcoal, and administration of N-acetylcysteine for paracetamol toxicity. Supportive care for cardiovascular and CNS effects.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Do not exceed the recommended dose of this medicine. Avoid driving or operating heavy machinery if you feel drowsy. Do not take this medicine with other products containing paracetamol or phenylephrine to prevent overdose. Avoid alcohol while taking this medicine as it can increase drowsiness and liver risk. Inform your doctor if you have high blood pressure, heart disease, diabetes, thyroid disorders, or liver/kidney problems. Do not use for more than 7 days without medical advice. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the effects of phenylephrine and fexofenadine. Use with caution and lower doses may be appropriate. Monitor blood pressure and heart rate regularly.
🤰 Pregnancy Planning (TTC)
Consult your doctor before taking this medicine if you are planning pregnancy. Fexofenadine is generally considered low risk, but phenylephrine may not be recommended. Paracetamol is considered safe at recommended doses.
🏥 Post-Surgery Considerations
Consult your doctor before taking this medicine after surgery, especially if you are taking other medications or have cardiovascular concerns.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine, as it may interact with medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you feel drowsy or dizzy after taking this medicine, avoid exercise until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also cause nervousness, which can impact concentration.
🛑 When to Stop This Medicine
Stop this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any severe side effects. Do not stop abruptly if you have been taking it regularly for a long time without medical advice.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended. Prolonged use of phenylephrine can cause rebound congestion. Paracetamol overuse can lead to liver damage. Regular monitoring of blood pressure and liver function may be needed if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help relieve nasal congestion without medication.
Evidence: Well-establishedHelps loosen mucus and relieve congestion.
Evidence: SupportiveReducing exposure to allergens can prevent symptoms.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from direct sunlight. If traveling across time zones, adjust dosing times gradually. Check customs regulations for carrying medicines. Do not leave in a hot car.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working within 30-60 minutes, with peak effects in 1-2 hours.
A: It is best taken with food or milk to reduce stomach upset.
A: Pediatric dosing is not established. Consult a pediatrician.
A: Do not take with other products containing paracetamol or phenylephrine to avoid overdose.
🤔 Common Patient Concerns
🔄 Substitutes for sinarest fxp tablet
View AllAlternative brands with exact same active ingredient:
-
coldifen tabletDharam Lifesciences ₹70.00 36.9% CHEAPER
-
Nam Cold FX 60mg/10mg/325mg TabletLincoln Pharmaceuticals Ltd ₹92.65 16.5% CHEAPER
-
genactive tabletEigen Pharmaceuticals Pvt Ltd ₹112.50 1.4% COSTLIER
-
CNF Activ TabletEris Lifesciences Ltd ₹121.55 9.5% COSTLIER
-
namcold fx tabletLincoln Pharmaceuticals Ltd ₹131.80 18.8% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine only relieves symptoms; it does not cure the underlying viral infection. - Myth: It is safe to take extra doses for faster relief.
Fact: Taking more than the recommended dose can cause serious side effects, including liver damage and hypertensive crisis. - Myth: It is safe to take with other cold medicines.
Fact: Many cold medicines contain paracetamol or phenylephrine; combining them can lead to overdose.
🔄 Alternative Options
Generic Alternatives
- Fexofenadine + Phenylephrine + Paracetamol (generic)