coldifen tablet - Uses, Price, Side Effects & Substitutes
What is coldifen tablet used for?
Coldifen Tablet (Fexofenadine + Phenylephrine) is used to treat RESPIRATORY. It contains Fexofenadine (60mg) + Phenylephrine (10mg), which Fexofenadine is a peripheral H1-receptor antagonist; Phenylephrine is a selectiv. Always consult your doctor before use. Take as prescribed.
- Generic Name: Fexofenadine + Phenylephrine
- Manufacturer: Dharam Lifesciences
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ coldifen tablet Uses & Benefits
Symptomatic relief of allergic rhinitis and common cold symptoms (nasal congestion, sneezing, rhinorrhea).
Off-label uses: None well-established.
๐ Drug Information
| Generic Name(s) | Fexofenadine + Phenylephrine |
| Brand Name | Coldifen Tablet |
| Manufacturer | Dharam Lifesciences |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Antihistamine + Decongestant |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Fexofenadine is a peripheral H1-receptor antagonist; Phenylephrine is a selective alpha-1 adrenergic receptor agonist.
Mechanism Steps
๐ก How to Take coldifen tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of coldifen tablet
โ Common Side Effects
- Headache
- Dizziness
- Dry mouth
- Nausea
- Insomnia
- Nervousness
๐จ Serious Side Effects
- Hypertension
- Palpitations
- Tachycardia
- Allergic reactions
- Urinary retention
โ ๏ธ Rare Side Effects
- Hypersensitivity reactions
- Arrhythmias
- Seizures
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Hypertensive crisis |
| Beta-blockers | Moderate | Reduced efficacy of phenylephrine |
| Antacids | Minor | Decreased fexofenadine absorption |
๐จ Major Interactions
- MAOIs
- Rasagiline
- Selegiline
- Linezolid
- Methylene Blue
โก Moderate Interactions
- Beta-blockers
- Tricyclic antidepressants
- Sympathomimetics
- Ergot alkaloids
โน๏ธ Minor Interactions
- Antacids
- Fruit juices (grapefruit, apple, orange)
๐ฝ๏ธ Food Interactions
Fruit juices (grapefruit, apple, orange) may decrease fexofenadine absorption; avoid taking with fruit juices.
๐ท Alcohol Interaction
Alcohol may increase CNS depression; avoid concurrent use.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hypertension, coronary artery disease, MAOI use within 14 days, narrow-angle glaucoma, urinary retention.
๐ Monitoring Parameters
Blood pressure, heart rate, symptom relief, CNS effects.
๐คฑ Lactation Safety
Caution; fexofenadine excreted in breast milk, phenylephrine unknown.
๐ Overdose Management
Supportive care; for fexofenadine: sedation, dizziness; for phenylephrine: hypertension, bradycardia. Treat symptomatically.
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose. Do not double dose.