Seftriax T 500mg/62.5mg Injection - Ceftriaxone (500mg) + Tazobactum (62.5mg) medicine

Augtaz 500 mg/62.5 mg Injection: Complete Medicine Guide

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🏭 Alobiote Healthcare 📦 vial of 1 Injection 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or swelling of face, lips, or throat
  • Severe diarrhea or bloody stools
  • Seizures or confusion
  • Decreased urine output
  • Yellowing of skin or eyes
  • Severe abdominal pain

If experiencing severe symptoms, call emergency services immediately.

What is Seftriax T 500mg/62.5mg Injection used for?

This medicine is a combination antibiotic injection containing ceftriaxone and tazobactum, used to treat serious bacterial infections. It is administered by a healthcare professional.

  • Generic Name: Ceftriaxone (500mg) + Tazobactum (62.5mg)
  • Manufacturer: Alobiote Healthcare
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 Seftriax T 500mg/62.5mg Injection के बारे में (Hindi Summary)

उपयोग: यह दवा सेफ्ट्रिएक्सोन और टैज़ोबैक्टम का संयोजन है, जिसका उपयोग गंभीर बैक्टीरियल संक्रमणों जैसे निमोनिया, मूत्र मार्ग संक्रमण, त्वचा संक्रमण और मेनिनजाइटिस के इलाज के लिए किया जाता है। यह इंजेक्शन के रूप में डॉक्टर द्वारा दी जाती है।

साइड इफेक्ट्स: सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, दस्त, मतली, उल्टी और दाने शामिल हैं। गंभीर दुष्प्रभावों में एलर्जी, गंभीर दस्त और रक्त विकार हो सकते हैं। किसी भी असामान्य लक्षण की तुरंत डॉक्टर को सूचना दें।

सुरक्षा सलाह: यह दवा केवल प्रशिक्षित स्वास्थ्यकर्मी द्वारा ही दी जानी चाहिए। अपनी सभी एलर्जी और चिकित्सीय स्थितियों के बारे में डॉक्टर को बताएं। पूरा कोर्स पूरा करें। गंभीर दस्त, दाने या सांस लेने में कठिनाई हो तो तुरंत डॉक्टर से मिलें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 Seftriax T 500mg/62.5mg Injection Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used to treat moderate to severe bacterial pneumonia caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"Effective against many Gram-negative bacteria causing pyelonephritis and complicated UTIs.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used in combination with other antibiotics for intra-abdominal sepsis and peritonitis.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"Used for empirical therapy of bacterial meningitis in adults and children.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"Single-dose therapy for uncomplicated gonorrhea caused by susceptible strains.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used off-label for disseminated Lyme disease, though other agents are preferred.","evidence":"Limited"},{"condition":"Typhoid fever","description":"May be used off-label where susceptibility is confirmed, but resistance is common.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Pneumonia, Urinary tract infections, Intra-abdominal infections, Skin infections, Meningitis

📋 Drug Information

Generic Name(s)Ceftriaxone (500mg) + Tazobactum (62.5mg)
Brand NameSeftriax T 500mg/62.5mg Injection
ManufacturerAlobiote Healthcare
Packaging / Formvial of 1 Injection (Allopathy)
Therapeutic Class
Action Class
Route of AdministrationParenteral (intravenous or intramuscular)
StorageStore the powder at room temperature (15-30°C) in a dry place, protected from light. After reconstitution, use immediately or store as directed by the pharmacist.
Shelf LifeTypically 24 months from the date of manufacture. Refer to the package label.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always reconstitute the powder as directed by the manufacturer.
2
Administer intravenously over 2-4 minutes or intramuscularly with lidocaine if needed.
3
Monitor renal and liver function during therapy.
4
Watch for signs of anaphylaxis during the first dose.
5
Complete the full course to prevent resistance.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough
May be used for bacterial pneumonia.
Likely Use
✅
Burning urination
May be used for urinary tract infections.
Likely Use
❌
Runny nose
Not effective for viral colds.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot applicable; this medicine is administered parenterally and is completely bioavailable.
DistributionCeftriaxone distributes widely into body tissues and fluids, including cerebrospinal fluid, bile, and synovial fluid. Tazobactum distributes into extracellular fluid.
Protein BindingCeftriaxone is highly protein-bound (85-95%). Tazobactum is approximately 20-30% protein-bound.
MetabolismCeftriaxone is not significantly metabolized. Tazobactum is partially metabolized to inactive metabolites.
Half-LifeCeftriaxone: 6-9 hours in healthy adults. Tazobactum: approximately 1 hour.
ExcretionCeftriaxone is excreted unchanged in urine and bile. Tazobactum is excreted primarily in urine.
Bioavailability100% (parenteral administration).
Onset of ActionRapid; therapeutic levels achieved immediately after intravenous administration.
Peak Plasma TimeImmediately after intravenous infusion; 1-2 hours after intramuscular injection.
Duration of ActionCeftriaxone: up to 24 hours; Tazobactum: shorter duration but synergistic effect.

How It Works

Ceftriaxone inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, preventing peptidoglycan cross-linking. Tazobactum is a beta-lactamase inhibitor that protects ceftriaxone from enzymatic degradation by certain beta-lactamases, thereby extending its spectrum against beta-lactamase-producing bacteria.

Mechanism Steps

1
Ceftriaxone binds PBPs: Ceftriaxone binds to penicillin-binding proteins on the bacterial cell membrane, inhibiting cell wall synthesis.
2
Tazobactum inhibits beta-lactamases: Tazobactum irreversibly binds to beta-lactamase enzymes, preventing them from hydrolyzing ceftriaxone.
3
Bacterial cell lysis: Without a functional cell wall, bacteria undergo lysis and die.

💡 How to Take Seftriax T 500mg/62.5mg Injection

Strength: Injection: Ceftriaxone 500 mg + Tazobactum 62.5 mg per vial.

1This medicine is given by a healthcare professional.
2It is administered intravenously or intramuscularly.
3The dose and frequency are determined by your doctor.
4Do not attempt to self-administer.
5Report any side effects immediately.

Dosage Information

Adult DosageThe usual adult dose is 1-2 grams of ceftriaxone with 125-250 mg of tazobactum every 12-24 hours, depending on the infection severity and site. For severe infections, higher doses may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal function. Use with caution and monitor closely.
Renal ImpairmentIn patients with severe renal impairment (creatinine clearance <30 mL/min), dose adjustment may be necessary. Consult a clinician.
Hepatic ImpairmentNo specific dose adjustment is typically required for hepatic impairment alone, but monitor liver function.
Maximum Daily DoseThe maximum daily dose is 4 grams of ceftriaxone and 500 mg of tazobactum, but must be individualized.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

⏰ What to Do If You Miss a Dose

📌 Missed dose due to appointment delay
→ Contact your healthcare provider for rescheduling.
💡 Do not attempt to self-administer.

⚠️ Side Effects of Seftriax T 500mg/62.5mg Injection

✅ Common Side Effects

Injection site pain (Common (5-10%))
Apply cold compress; report if severe.
Diarrhea (Common (5-10%))
Stay hydrated; report if persistent or bloody.
Nausea (Common (3-5%))
Take antiemetic if prescribed; report if severe.
Rash (Common (2-5%))
Report to doctor; may indicate allergy.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek emergency medical help immediately.
Clostridioides difficile colitis (Uncommon (0.1-1%))
Report severe or bloody diarrhea; may require treatment.
Hemolytic anemia (Rare (<0.1%))
Report unusual fatigue, jaundice, or dark urine.
Seizures (Rare (<0.1%))
Seek immediate medical attention.

⚠️ Rare Side Effects

Pancreatitis
Report severe abdominal pain.
Interstitial nephritis
Report decreased urine output or swelling.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Calcium-containing IV solutions Major
Loop diuretics Moderate
Aminoglycosides Moderate

🚨 Major Interactions

  • Warfarin
  • Calcium-containing IV solutions

⚡ Moderate Interactions

  • Loop diuretics
  • Aminoglycosides

🍷 Alcohol Interaction

Avoid alcohol during treatment as it may worsen side effects and impair recovery.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known severe allergy to cephalosporins or beta-lactam antibiotics","Neonates with hyperbilirubinemia","Concomitant use with calcium-containing IV solutions in neonates"]

⚠️ Warnings & Precautions

["Use with caution in patients with penicillin allergy due to cross-reactivity.","Adjust dose in severe renal impairment.","May cause false-positive urine glucose tests.","Avoid in patients with a history of colitis.","Monitor for superinfections."]

🤱 Lactation Safety

Ceftriaxone is excreted in breast milk in low amounts. Use with caution; consult your doctor.

💊 Overdose Management

Overdose may cause nausea, vomiting, and seizures. Treatment is supportive and symptomatic. Contact a poison control center or emergency department immediately.

⏰ Missed Dose

Since this medicine is administered by a healthcare professional, missed doses are unlikely. If a dose is missed, contact your doctor for guidance. Do not attempt to self-administer.

Additional Safety Advice

General Safety

This medicine must be administered only by a trained healthcare professional. Inform your doctor about all allergies, especially to penicillins or cephalosporins, and about any kidney or liver problems. Do not self-administer. Complete the full course as prescribed, even if you feel better. Report severe diarrhea, rash, or difficulty breathing immediately. Avoid alcohol during treatment. Use with caution in elderly patients and those with seizure disorders. Do not use if the solution is cloudy or contains particles.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced renal function and require dose adjustment. Monitor closely for side effects.

🤰 Pregnancy Planning (TTC)

Consult your doctor if you are planning pregnancy. Use only if clearly needed.

🏥 Post-Surgery Considerations

May be used to prevent or treat surgical site infections. Follow your surgeon's instructions.

🦷 Dental Procedures

Inform your dentist if you are receiving this medicine. It may be used for prophylaxis in certain dental procedures.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest to aid recovery.
🥗
Stay hydrated by drinking fluids.
😴
Maintain good hand hygiene to prevent infection spread.
💧
Eat a balanced diet to support immune function.
🧘
Avoid close contact with sick individuals.

🏋️ Exercise Considerations

Rest is recommended during acute infection. Gradually resume exercise as you recover, but avoid strenuous activity until cleared by your doctor.

🥗 Diet Recommendations

Drink plenty of water
Eat light, nutritious meals
Include probiotics if advised by your doctor

💼 Impact on Daily Work & Life

You may need to take time off work during treatment, especially if hospitalized. Driving is not recommended if you feel weak or dizzy.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. Complete the full course as prescribed.

📅 Long-Term Use Effects

Long-term use may lead to antibiotic resistance, superinfections, and rarely, blood or liver abnormalities. Regular monitoring is advised for prolonged therapy.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral antibiotics

May be used after initial improvement with injection.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific vaccine interactions are established. Continue routine vaccinations as per schedule.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

This medicine is administered by a healthcare professional, so travel is not applicable. If you are traveling after treatment, carry a copy of your prescription and medical records. Store any remaining medication as directed.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 60-year-old man with community-acquired pneumonia
He was admitted and started on this medicine. His fever subsided within 48 hours, and he completed a 7-day course. He reported mild diarrhea, which resolved after treatment.
💡 Lesson: This medicine is effective for pneumonia when used as prescribed, and side effects are usually manageable.
👤 A 35-year-old woman with complicated urinary tract infection
She received this medicine intravenously for 5 days. Her symptoms improved significantly, and she was switched to oral antibiotics. She experienced no serious side effects.
💡 Lesson: This medicine can effectively treat complicated UTIs and may be followed by oral therapy.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Improvement is usually seen within 24-48 hours, but complete recovery depends on the infection.

Q: Can I stop the injection if I feel better?

A: No, you must complete the full course as prescribed to prevent resistance.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine if I am allergic to penicillin?
  • How long will I need this injection?
  • Can I drink alcohol during treatment?
  • Will this medicine affect my kidney?
  • Can I drive after receiving this injection?

🔄 Substitutes for Seftriax T 500mg/62.5mg Injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections.
    Fact: This medicine is effective only against bacterial infections.
  • Myth: You can stop the injection once you feel better.
    Fact: You must complete the full course as prescribed to prevent resistance.

🔄 Alternative Options

Generic Alternatives

  • Ceftriaxone + Tazobactum injection

Brand Alternatives

  • Other brands containing ceftriaxone and tazobactum

📊 Comparison with Similar Medicines

[{"medicine":"Ceftriaxone + Tazobactum","difference":"Broad-spectrum with beta-lactamase inhibition."},{"medicine":"Ceftriaxone alone","difference":"Lacks beta-lactamase inhibition; narrower spectrum."}]

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