Appime T 500mg/62.5mg Injection: Comprehensive Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of face, lips, or throat
- Severe or bloody diarrhea
- Seizures or confusion
- Decreased urine output or swelling
- Severe skin rash with blistering or peeling
- Yellowing of skin or eyes
- Persistent high fever despite treatment
If experiencing severe symptoms, call emergency services immediately.
What is scud xp 500 mg/62.5 mg injection used for?
This medicine is a combination antibiotic injection containing cefepime and tazobactum. It is used to treat serious bacterial infections. It works by killing bacteria and is given by a healthcare professional.
- Generic Name: Cefepime (500mg) + Tazobactum (62.5mg)
- Manufacturer: Zuventus Healthcare Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 scud xp 500 mg/62.5 mg injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफेपाइम और टैज़ोबैक्टम का संयोजन है, जिसका उपयोग गंभीर जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग, पेट, त्वचा और फेफड़ों के संक्रमण में प्रभावी है। यह दवा केवल डॉक्टर या नर्स द्वारा इंजेक्शन के रूप में दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, दस्त, मतली, सिरदर्द और दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर दस्त, दौरे और गुर्दे की समस्या हो सकती है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: यह दवा केवल अस्पताल या क्लिनिक में डॉक्टर या नर्स द्वारा दी जानी चाहिए। इसे स्वयं न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों और एलर्जी के बारे में बताएं। गुर्दे की बीमारी होने पर खुराक बदलनी पड़ सकती है। इलाज के दौरान शराब न पिएं। पूरा कोर्स पूरा करें।
💊 scud xp 500 mg/62.5 mg injection Uses & Benefits
[{"condition":"Complicated urinary tract infections","description":"Used to treat serious kidney and bladder infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Effective against infections in the abdominal cavity, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats severe skin infections including cellulitis and abscesses.","evidence":"Well-established"},{"condition":"Hospital-acquired pneumonia","description":"Used for pneumonia acquired during hospital stay, including ventilator-associated pneumonia.","evidence":"Well-established"},{"condition":"Febrile neutropenia","description":"Empiric therapy for fever in patients with low white blood cell counts.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Bone and joint infections","description":"Sometimes used for osteomyelitis and septic arthritis when caused by susceptible organisms.","evidence":"Limited"},{"condition":"Meningitis","description":"May be used for bacterial meningitis, though other agents are often preferred.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Complicated urinary tract infections, Intra-abdominal infections, Skin and soft tissue infections, Pneumonia, Febrile neutropenia
📋 Drug Information
| Generic Name(s) | Cefepime (500mg) + Tazobactum (62.5mg) |
| Brand Name | scud xp 500 mg/62.5 mg injection |
| Manufacturer | Zuventus Healthcare Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | |
| Route of Administration | Parenteral (intravenous or intramuscular injection) |
| Storage | Store the unreconstituted powder at room temperature between 20°C and 25°C (68°F to 77°F). Protect from light and moisture. After reconstitution, the solution should be used immediately or stored as directed by the pharmacist. Do not freeze. |
| Shelf Life | The shelf life of the unreconstituted powder is typically 24 months from the date of manufacture. After reconstitution, use within the time specified by the manufacturer, usually within 24 hours if refrigerated. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefepime, the active cephalosporin component, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial lysis and death. Tazobactum is a beta-lactamase inhibitor that irreversibly binds to certain beta-lactamase enzymes produced by bacteria, preventing them from hydrolyzing and inactivating cefepime. This combination extends the spectrum of cefepime against beta-lactamase-producing organisms.
Mechanism Steps
💡 How to Take scud xp 500 mg/62.5 mg injection
Strength: Injection: Cefepime 500 mg + Tazobactum 62.5 mg per vial.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 500 mg to 2 grams of the cefepime component every 8 to 12 hours, depending on the type and severity of infection. The tazobactum component is fixed at 62.5 mg per 500 mg cefepime. For severe infections, higher doses may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. In patients with kidney impairment, the dose and frequency are adjusted according to creatinine clearance. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced kidney function, so dose adjustment based on creatinine clearance is often necessary. Monitor renal function closely during treatment. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine must be adjusted based on creatinine clearance. For creatinine clearance between 30-60 mL/min, the usual dose may be given every 12 hours. For creatinine clearance between 11-29 mL/min, the dose may be given every 24 hours. For patients on hemodialysis, a dose is given after each dialysis session. Always consult a clinician for precise dosing. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment alone. However, if both hepatic and renal impairment are present, dose adjustment based on renal function is necessary. |
| Maximum Daily Dose | The maximum recommended daily dose is 6 grams of cefepime (e.g., 2 grams every 8 hours) for adults with normal kidney function. Doses above this are not recommended. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of scud xp 500 mg/62.5 mg injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Aminoglycosides | Major | |
| Loop diuretics | Major | |
| Warfarin | Major | |
| Probenecid | Moderate | |
| Chloramphenicol | Moderate |
🚨 Major Interactions
- Aminoglycosides (e.g., gentamicin, tobramycin)
- Loop diuretics (e.g., furosemide)
- Warfarin
⚡ Moderate Interactions
- Probenecid
- Chloramphenicol
🍷 Alcohol Interaction
Alcohol should be avoided while receiving this medicine as it may worsen side effects such as nausea, dizziness, and stomach upset. It may also increase the risk of liver-related side effects.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to cefepime, tazobactum, or other cephalosporins","History of anaphylaxis to penicillins or other beta-lactam antibiotics","Use in patients with a history of severe beta-lactam-associated immediate hypersensitivity reactions"]
⚠️ Warnings & Precautions
["Serious hypersensitivity reactions, including anaphylaxis, can occur. Discontinue immediately if a reaction occurs.","Clostridium difficile-associated diarrhea may develop during or after treatment. Monitor for severe diarrhea.","Use with caution in patients with renal impairment; dose adjustment is necessary.","May cause seizures, especially in patients with renal impairment or underlying CNS disorders.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","Not effective against viral infections. Do not use for colds or flu.","Should be used only when a bacterial infection is confirmed or strongly suspected."]
🤱 Lactation Safety
Cefepime is excreted in human milk in low amounts. Tazobactum excretion is unknown. Caution is advised; consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
Overdose can cause severe nausea, vomiting, seizures, and kidney damage. Treatment is supportive and symptomatic. Hemodialysis may be considered to remove cefepime from the blood in severe cases. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
Since this medicine is administered by a healthcare professional, missed doses are unlikely. If you miss a scheduled dose, contact your doctor or nurse as soon as possible to reschedule. Do not attempt to self-administer an extra dose.
Additional Safety Advice
This medicine must be administered only by a qualified healthcare professional in a clinical setting. Before receiving this medicine, inform your doctor about all your medical conditions, especially kidney disease, colitis, or any allergies to antibiotics. Do not attempt to self-administer this injection. Complete the full course as prescribed, even if you feel better, to prevent the infection from returning and to reduce the risk of antibiotic resistance. Report any new symptoms such as severe diarrhea, rash, or difficulty breathing immediately. Your doctor may adjust the dose if you have kidney problems. Avoid alcohol during treatment as it may worsen side effects. Keep all follow-up appointments and laboratory tests as advised.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, so dose adjustment is often necessary. They may also be more susceptible to side effects like confusion and seizures. Close monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before starting this medicine. It is generally used only if clearly needed during pregnancy. Discuss the risks and benefits with your healthcare provider.
🏥 Post-Surgery Considerations
This medicine is often used after surgery to prevent or treat infections. It is administered in the hospital setting. Follow your surgeon's instructions regarding wound care and follow-up.
🦷 Dental Procedures
Inform your dentist if you are receiving this medicine, as it may interact with other medications or affect your ability to undergo certain procedures. No specific precautions are typically required.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise during treatment, especially if you feel weak or dizzy. Light activity like walking is fine if you feel up to it. Consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue. Avoid driving or operating heavy machinery until you know how it affects you. You may need to take time off work during treatment, especially if hospitalized.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Stopping early can lead to recurrence of infection and antibiotic resistance. Your doctor will determine when to stop based on your clinical response and test results.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, fungal superinfections, and rarely, kidney or liver problems. Regular monitoring of renal and hepatic function is advised during prolonged therapy. It should only be used for as long as necessary.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For mild infections, oral antibiotics may be used instead of injections.
Evidence: Well-establishedDepending on the causative organism, other antibiotics like carbapenems or fluoroquinolones may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, inform your doctor if you have recently received any vaccines or plan to receive one soon.
📦 Storage Guide
✅ DO
Store at room temperature (20-25°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Protect from light and moisture
❌ DON'T
Do not store in bathroom
✈️ Traveling with This Medicine
This medicine is administered in a healthcare setting, so travel is not applicable. If you are traveling after treatment, carry a copy of your prescription and medical records. Store any remaining medication as directed. Inform your doctor if you plan to travel to areas with high risk of infections.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.
A: No, this medicine must be administered by a healthcare professional in a clinical setting.
A: Report any side effects to your doctor immediately. Do not ignore severe symptoms.
🤔 Common Patient Concerns
🔄 Substitutes for scud xp 500 mg/62.5 mg injection
View AllAlternative brands with exact same active ingredient:
-
Tazowok 500 mg/62.5 mg InjectionWockhardt Ltd ₹112.50 26.9% CHEAPER
-
keftaaz hs 500 mg/62.5 mg injectionMacleods Pharmaceuticals Pvt Ltd ₹123.83 19.6% CHEAPER
-
cedil 500 mg/62.5 mg injectionEmcure Pharmaceuticals Ltd ₹158.30 2.8% COSTLIER
-
appime t 500mg/62.5mg injectionApkavit Lifesciences ₹159.38 3.5% COSTLIER
-
kanpime tz 500mg/62.5mg injectionFortune Life Sciences Private Limited ₹185.00 20.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe to self-administer at home.
Fact: This medicine must only be given by a healthcare professional in a clinical setting.
🔄 Alternative Options
Generic Alternatives
- Cefepime + Tazobactum injection (generic versions may be available)
Brand Alternatives
- Appime T 500mg/62.5mg injection