augpen lb 625 tablet - Amoxycillin (500mg) + Clavulanic Acid (125mg) medicine

augpen lb 625 tablet

No reviews yet
🏭 Zuventus Healthcare Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 20, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 20, 2026

What is augpen lb 625 tablet used for?

This medicine contains Amoxycillin (500mg) + Clavulanic Acid (125mg) and is used to treat ANTI INFECTIVES. Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs);. Always consult your doctor before use.

  • Generic Name: Amoxicillin + Clavulanic Acid
  • Manufacturer: Zuventus Healthcare Ltd
  • Form: Allopathy
  • Pregnancy Category: Category B
  • Prescription Required: Yes
💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 augpen lb 625 tablet Uses & Benefits

Respiratory tract infections, Urinary tract infections, Skin and soft tissue infections, Otitis media, Sinusitis, Bone and joint infections

Off-label uses: Prophylaxis in dental procedures (for endocarditis risk), Lyme disease (early localized)

📋 Drug Information

Generic Name(s)Amoxicillin + Clavulanic Acid
Brand NameAmoxyclav 625 Tablet
ManufacturerZuventus Healthcare Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassPenicillin Antibiotics
Route of AdministrationOral
StorageStore at room temperature (20-25°C); protect from moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed from the gastrointestinal tract; food does not affect absorption.
DistributionDistributes widely into body tissues and fluids; crosses placenta and enters breast milk.
Protein BindingAmoxicillin: ~20%; Clavulanic Acid: ~30%.
MetabolismAmoxicillin: partially metabolized; Clavulanic Acid: extensively metabolized.
Half-LifeAmoxicillin: ~1 hour; Clavulanic Acid: ~1 hour.
ExcretionPrimarily renal (tubular secretion) for both; small amount in feces.
Bioavailability~90% for amoxicillin; well absorbed for clavulanic acid.
Onset of ActionWithin 1-2 hours.
Peak Plasma Time1-2 hours.
Duration of Action6-8 hours.

How It Works

Amoxicillin inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs); clavulanic acid is a beta-lactamase inhibitor that prevents inactivation of amoxicillin by resistant bacteria.

Mechanism Steps

1Amoxicillin binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
2Inhibits transpeptidase enzymes, preventing cross-linking of peptidoglycan chains.
3Activates autolytic enzymes, leading to cell lysis and death.
4Clavulanic acid binds to beta-lactamases, inhibiting their activity.
5Prevents hydrolysis of amoxicillin, restoring its antibacterial activity against resistant strains.

💡 How to Take augpen lb 625 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of augpen lb 625 tablet

✅ Common Side Effects

Diarrhea
Nausea
Vomiting
Rash
Vaginal candidiasis

🚨 Serious Side Effects

Anaphylaxis
Stevens-Johnson syndrome
Cholestatic jaundice
Pseudomembranous colitis
Seizures (high doses)

⚠️ Rare Side Effects

Agranulocytosis
Hemolytic anemia
Interstitial nephritis
Hepatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

🚨 Major Interactions

  • Methotrexate (increased toxicity)
  • Warfarin (increased INR)
  • Allopurinol (increased rash risk)

⚡ Moderate Interactions

  • Oral contraceptives (reduced efficacy)
  • Probenecid (increased amoxicillin levels)
  • Mycophenolate (decreased levels)

🍷 Alcohol Interaction

No direct interaction; but alcohol may reduce immune response.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to penicillins or beta-lactam antibiotics, History of cholestatic jaundice/hepatic dysfunction with amoxicillin-clavulanate, Infectious mononucleosis (risk of rash)

🤱 Lactation Safety

Compatible; small amounts excreted in breast milk; monitor for diarrhea or rash in infant.

💊 Overdose Management

Supportive care; activated charcoal if recent ingestion; hemodialysis may help.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double.

🔄 Substitutes for augpen lb 625 tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory