biopime 500mg injection - Cefepime (500mg) medicine

Biopime 500mg Injection - Uses, Price, Side Effects

4.5 (16 reviews)

Cefepime (500mg)

🏭 Biochem Pharmaceutical Industries 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is biopime 500mg injection used for?

Biopime 500mg Injection contains Cefepime, a fourth-generation cephalosporin antibiotic. It works by killing bacteria or stopping their growth, and is used to treat various bacterial infections including pneumonia, urinary tract infections, skin infections, and intra-abdominal infections. It is administered intravenously or intramuscularly under medical supervision.

Generic Name: Cefepime
Manufacturer: Biochem Pharmaceutical Industries
Form: Allopathy
Pregnancy Category: B
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 biopime 500mg injection Uses & Benefits

Treatment of pneumonia, urinary tract infections, skin and soft tissue infections, intra-abdominal infections, febrile neutropenia.

Off-label uses: Meningitis, Osteomyelitis

📋 Drug Information

Generic Name(s)	Cefepime
Brand Name	Appime 250mg Injection
Manufacturer	Biochem Pharmaceutical Industries
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI INFECTIVES
Action Class	Cephalosporins: 4th generation
Route of Administration	Intravenous (IV) or intramuscular (IM)
Storage	Store at 20-25°C (68-77°F); protect from light.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability.

DistributionWidely distributed into tissues and body fluids including cerebrospinal fluid.

Protein BindingApproximately 20%

MetabolismPartially metabolized to N-methylpyrrolidine (NMP) which is rapidly converted to N-methylpyrrolidine oxide.

Half-LifeApproximately 2 hours

ExcretionPrimarily excreted unchanged in urine via glomerular filtration and tubular secretion.

Bioavailability100% (intravenous)

Onset of ActionRapid

Peak Plasma TimeEnd of infusion

Duration of ActionApproximately 12 hours

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis.

Mechanism Steps

1Cefepime binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall.

2Inhibition of transpeptidase enzymes prevents cross-linking of peptidoglycan chains.

3Autolytic enzymes are activated, leading to cell wall degradation and bacterial lysis.

💡 How to Take biopime 500mg injection

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of biopime 500mg injection

✅ Common Side Effects

Diarrhea
Nausea
Vomiting
Rash
Injection site reactions

🚨 Serious Side Effects

Anaphylaxis
Clostridioides difficile colitis
Seizures
Acute renal failure

⚠️ Rare Side Effects

Hemolytic anemia
Agranulocytosis
Stevens-Johnson syndrome

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Aminoglycosides	Moderate	Increased nephrotoxicity
Probenecid	Moderate	Reduced renal excretion of cefepime

🚨 Major Interactions

Aminoglycosides
Loop diuretics
Probenecid

⚡ Moderate Interactions

Warfarin
Oral contraceptives

ℹ️ Minor Interactions

Antacids

🍽️ Food Interactions

No significant food interactions.

🍷 Alcohol Interaction

No known interaction.

🛡️ Safety & Warnings

Liver

Low

Kidney

Moderate

Heart

Low

Pregnancy

Category B

🚫 Contraindications

Hypersensitivity to cefepime or other cephalosporins, penicillins, or beta-lactam antibiotics.

📊 Monitoring Parameters

Renal function, complete blood count, signs of hypersensitivity, superinfection.

🤱 Lactation Safety

Excreted in breast milk in low concentrations; use with caution.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination.

⏰ Missed Dose

Administer as soon as remembered; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for biopime 500mg injection

View All

Alternative brands with exact same active ingredient (Cefepime (500mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Regular Customer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.