Es-Que 300mg Tablet SR (Quetiapine): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- High fever with muscle stiffness and confusion
- Involuntary movements of the face, tongue, or limbs
- Irregular heartbeat or fainting
- Severe allergic reaction (rash, swelling, difficulty breathing)
- Signs of high blood sugar (excessive thirst, frequent urination, fatigue)
- Yellowing of skin or eyes
- Thoughts of harming yourself or others
If experiencing severe symptoms, call emergency services immediately.
What is Scool 300mg Tablet used for?
This medicine is a prescription atypical antipsychotic used to treat schizophrenia, bipolar disorder, and as an add-on for major depressive disorder. It works by balancing dopamine and serotonin in the brain. Common side effects include drowsiness, dizziness, and weight gain. It should be taken exactly as prescribed and not stopped abruptly.
- Generic Name: Quetiapine (300mg)
- Manufacturer: Shatayushi Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 Scool 300mg Tablet के बारे में (Hindi Summary)
उपयोग: यह दवा क्वेटियापिन 300 मिलीग्राम की है, जिसका उपयोग सिज़ोफ्रेनिया, बाइपोलर डिसऑर्डर और अवसाद के इलाज में किया जाता है। यह मस्तिष्क में डोपामाइन और सेरोटोनिन के स्तर को संतुलित करने में मदद करती है। यह दवा केवल डॉक्टर के पर्चे पर ही मिलती है और इसे डॉक्टर की सलाह के बिना बंद नहीं करना चाहिए।
साइड इफेक्ट्स: आम दुष्प्रभावों में नींद आना, चक्कर आना, मुँह सूखना, वजन बढ़ना और भूख बढ़ना शामिल हैं। गंभीर दुष्प्रभावों में न्यूरोलेप्टिक मैलिग्नेंट सिंड्रोम, टार्डिव डिस्किनेसिया, उच्च रक्त शर्करा और हृदय की धड़कन में बदलाव शामिल हो सकते हैं। किसी भी असामान्य लक्षण को तुरंत डॉक्टर को बताएं।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे अचानक बंद न करें। शराब का सेवन न करें। यदि आपको हृदय, मधुमेह, दौरे या यकृत की समस्या है तो डॉक्टर को बताएं। नियमित रूप से रक्त शर्करा, कोलेस्ट्रॉल और वजन की जांच कराएं। इस दवा से नींद आ सकती है, इसलिए वाहन चलाने या मशीनरी चलाने से बचें।
💊 Scool 300mg Tablet Uses & Benefits
[{"condition":"Schizophrenia","description":"This medicine helps to reduce hallucinations, delusions, and disorganized thinking associated with schizophrenia.","evidence":"Well-established"},{"condition":"Bipolar disorder","description":"This medicine is used to treat manic episodes and depressive episodes associated with bipolar disorder.","evidence":"Well-established"},{"condition":"Major depressive disorder (adjunctive)","description":"This medicine is used as an add-on treatment to antidepressants for major depressive disorder.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Generalized anxiety disorder","description":"Sometimes prescribed off-label for severe anxiety when other treatments are ineffective.","evidence":"Limited"},{"condition":"Insomnia","description":"Low doses may be used off-label for short-term management of insomnia.","evidence":"Limited"},{"condition":"Post-traumatic stress disorder","description":"May be used off-label as an adjunct for PTSD symptoms.","evidence":"Limited"}]
Primary treatment for: Schizophrenia
Also treats: Bipolar disorder, Major depressive disorder
📋 Drug Information
| Generic Name(s) | Quetiapine (300mg) |
| Brand Name | Scool 300mg Tablet |
| Manufacturer | Shatayushi Healthcare Pvt Ltd |
| Packaging / Form | strip of 10 tablets (Allopathy) |
| Therapeutic Class | |
| Action Class | |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking the effects of dopamine and serotonin in the brain. It acts as an antagonist at dopamine D2 receptors and serotonin 5-HT2A receptors. This helps to reduce psychotic symptoms and stabilize mood. It also has effects on histamine H1 and adrenergic alpha-1 receptors, which contribute to its sedative and blood pressure-lowering effects.
Mechanism Steps
💡 How to Take Scool 300mg Tablet
Strength: Sustained-release tablet, 300 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine for schizophrenia is 150 mg to 750 mg per day, divided into two or three doses. For bipolar mania, the usual dose is 200 mg to 800 mg per day. For bipolar depression, the usual dose is 300 mg per day. For adjunctive treatment of major depressive disorder, the usual dose is 150 mg to 300 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require lower doses and slower titration. Start with a low dose and increase gradually. Use with caution due to increased risk of orthostatic hypotension, sedation, and falls. |
| Renal Impairment | No dose adjustment is required for patients with renal impairment. However, use with caution. |
| Hepatic Impairment | Dose reduction may be necessary in patients with hepatic impairment. Consult your doctor for appropriate dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 800 mg per day, but doses above 300 mg per day should be used with caution. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of Scool 300mg Tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Ketoconazole | Major | |
| Rifampin | Major | |
| Amiodarone | Major | |
| Lisinopril | Moderate | |
| Diazepam | Moderate | |
| Levodopa | Minor | |
| Ritonavir | Minor | |
| Carbamazepine | Major | |
| Fluconazole | Moderate | |
| Warfarin | Minor |
🚨 Major Interactions
- CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin)
- CYP3A4 inducers (e.g., rifampin, carbamazepine)
- Drugs that prolong QT interval (e.g., amiodarone, sotalol)
⚡ Moderate Interactions
- Antihypertensives
- Central nervous system depressants (e.g., benzodiazepines, alcohol)
- Anticholinergic drugs
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase drowsiness, dizziness, and difficulty concentrating, and may worsen the side effects of this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to quetiapine or any component of the formulation","Concomitant use with strong CYP3A4 inhibitors","Elderly patients with dementia-related psychosis (increased risk of death)"]
⚠️ Warnings & Precautions
["May cause drowsiness and dizziness; avoid driving or operating machinery until you know how it affects you.","May cause orthostatic hypotension; rise slowly from sitting or lying positions.","May increase blood sugar and cholesterol levels; monitor regularly.","May cause weight gain; maintain a healthy diet and exercise.","May cause neuroleptic malignant syndrome; seek immediate medical attention if symptoms occur.","May cause tardive dyskinesia; report involuntary movements to your doctor.","Do not stop this medicine abruptly; withdrawal symptoms may occur.","Use with caution in patients with a history of seizures, heart disease, or liver disease.","Avoid alcohol while taking this medicine.","Keep out of reach of children."]
🤱 Lactation Safety
This medicine is excreted in breast milk. Breastfeeding is not recommended while taking this medicine. Consult your doctor for alternative options.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Symptoms of overdose may include drowsiness, rapid heart rate, low blood pressure, and unconsciousness. Treatment is supportive and symptomatic. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not stop taking it suddenly, as this can cause withdrawal symptoms or worsening of your condition. Avoid alcohol while taking this medicine, as it can increase drowsiness and dizziness. Inform your doctor if you have a history of heart problems, diabetes, seizures, or liver disease. Regular monitoring of blood sugar, cholesterol, and weight is recommended. This medicine may cause drowsiness; avoid driving or operating machinery until you know how it affects you. Keep out of reach of children. Store at room temperature away from moisture and heat.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at increased risk of orthostatic hypotension, sedation, and falls. Lower doses and slower titration are recommended. This medicine is not approved for dementia-related psychosis due to increased risk of death.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor. This medicine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Discuss alternative options with your doctor.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and affect blood pressure and heart rate. Your doctor may adjust the dose before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may cause dry mouth, which can increase the risk of dental problems. Maintain good oral hygiene and stay hydrated.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause drowsiness and dizziness. Avoid strenuous exercise or activities that require alertness until you know how it affects you. Stay hydrated during exercise.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause drowsiness, dizziness, and difficulty concentrating, which can affect your ability to drive or operate machinery. Avoid these activities until you know how it affects you. It may also impact your work performance; discuss with your doctor if you have concerns.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. Your doctor will determine when and how to stop based on your condition and response to treatment. Abrupt discontinuation can cause withdrawal symptoms such as insomnia, nausea, and headache.
📅 Long-Term Use Effects
Long-term use of this medicine may increase the risk of metabolic syndrome, weight gain, diabetes, and cardiovascular disease. Regular monitoring of weight, blood sugar, cholesterol, and blood pressure is recommended. Tardive dyskinesia may occur with long-term use. Periodic evaluation of the need for continued treatment is advised.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for schizophrenia and bipolar disorder.
Evidence: Well-establishedRegular exercise, healthy diet, and stress management can improve overall well-being.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are established. Consult your doctor before receiving any vaccine while on this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage. Store at room temperature and avoid extreme temperatures. If traveling across time zones, consult your doctor for dose adjustment. Check customs regulations for controlled substances.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine may take several days to weeks to show full effects. Sedative effects may occur within 1-2 hours, but antipsychotic effects may take longer.
A: No, do not stop this medicine without consulting your doctor. Stopping abruptly can cause withdrawal symptoms or relapse.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
🤔 Common Patient Concerns
🔄 Substitutes for Scool 300mg Tablet
View AllAlternative brands with exact same active ingredient:
-
es-que 300mg tablet srEsteem Pharmaceuticals ₹105.00 44.4% CHEAPER
-
quticool 300mg tabletPsycormedies ₹109.57 42% CHEAPER
-
qtripril 300mg tablet srArinna Lifescience Pvt Ltd ₹133.93 29.1% CHEAPER
-
qutace 300mg tablet srLa Pharmaceuticals ₹144.43 23.6% CHEAPER
-
quitsun 300mg tabletSunrise Remedies Pvt Ltd ₹145.31 23.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is addictive.
Fact: This medicine is not addictive, but it can cause dependence if stopped abruptly. It should be tapered under medical supervision. - Myth: This medicine will cure my condition immediately.
Fact: This medicine may take several weeks to show full effects. It is important to continue taking it as prescribed. - Myth: I can stop taking this medicine once I feel better.
Fact: Do not stop this medicine without consulting your doctor. Stopping abruptly can cause withdrawal symptoms or relapse.
🔄 Alternative Options
Generic Alternatives
- Quetiapine fumarate
Brand Alternatives
- Seroquel XR
- Qutipin SR