Enzase 10000 Tablet: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe abdominal pain that does not go away.
- Blood in your stool or vomit.
- Signs of a severe allergic reaction, such as swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Persistent vomiting or inability to keep fluids down.
- Yellowing of the skin or eyes (jaundice).
- Decreased urine output or severe dehydration.
- New or worsening constipation with abdominal swelling.
If experiencing severe symptoms, call emergency services immediately.
What is sbz 10k capsule used for?
This medicine is a pancreatic enzyme replacement used to treat exocrine pancreatic insufficiency. It contains pancreatin, which helps digest fats, proteins, and carbohydrates. It is taken with meals and must be swallowed whole.
- Generic Name: Pancreatin (150mg)
- Manufacturer: Charan Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 sbz 10k capsule के बारे में (Hindi Summary)
उपयोग: यह दवा पैन्क्रियाटिन नामक एंजाइम से बनी है, जो पाचन में मदद करती है। यह उन लोगों के लिए है जिनके अग्नाशय (पैन्क्रियाज) पर्याप्त पाचक एंजाइम नहीं बना पाते, जिससे वसा, प्रोटीन और कार्बोहाइड्रेट ठीक से पच नहीं पाते। इस दवा का उपयोग क्रोनिक पैन्क्रियाटाइटिस, सिस्टिक फाइब्रोसिस, पैन्क्रियाज कैंसर और पैन्क्रियाज सर्जरी के बाद किया जाता है। यह दवा भोजन के साथ लेने से पाचन सुधरता है, पेट फूलना कम होता है, और वजन बढ़ाने में मदद मिलती है। इसे डॉक्टर की सलाह के अनुसार ही लें।
साइड इफेक्ट्स: इस दवा के आम दुष्प्रभावों में मतली, उल्टी, दस्त, कब्ज, पेट दर्द और पेट फूलना शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। कभी-कभी मुंह या गले में जलन हो सकती है, इसलिए दवा को पूरा निगलें, चबाएं नहीं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, या त्वचा पर चकत्ते दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को हमेशा भोजन के साथ लें और पूरा निगलें। दवा को चबाएं या कुचलें नहीं। डॉक्टर की सलाह के बिना दवा की खुराक न बदलें और न ही बंद करें। अगर आप गर्भवती हैं, स्तनपान करा रही हैं, या गर्भधारण की योजना बना रही हैं, तो डॉक्टर से सलाह लें। दवा को ठंडी, सूखी जगह पर, सीधी धूप से दूर, मूल पैकेट में रखें। बच्चों की पहुंच से दूर रखें।
💊 sbz 10k capsule Uses & Benefits
[{"condition":"Exocrine pancreatic insufficiency (EPI) due to chronic pancreatitis","description":"This medicine replaces missing digestive enzymes, helping to break down fats, proteins, and carbohydrates, which reduces steatorrhea and improves nutrient absorption.","evidence":"Well-established"},{"condition":"Exocrine pancreatic insufficiency due to cystic fibrosis","description":"Used to improve fat digestion and nutritional status in people with cystic fibrosis who have pancreatic enzyme deficiency.","evidence":"Well-established"},{"condition":"Exocrine pancreatic insufficiency after pancreatic surgery","description":"Helps restore digestion after removal of part or all of the pancreas, such as in Whipple procedure or total pancreatectomy.","evidence":"Well-established"},{"condition":"Exocrine pancreatic insufficiency due to pancreatic cancer","description":"Relieves symptoms of malabsorption and helps maintain weight and nutrition in people with pancreatic tumors.","evidence":"Well-established"},{"condition":"Steatorrhea of non-pancreatic origin","description":"May be used in some cases of fat malabsorption caused by other gastrointestinal conditions, but only under specialist guidance.","evidence":"Limited"}]
Off-label uses: [{"condition":"Chronic abdominal bloating and gas after meals","description":"Sometimes used off-label for functional dyspepsia or bloating, but evidence is not strong.","evidence":"Limited"},{"condition":"Celiac disease with persistent malabsorption","description":"Occasionally prescribed when pancreatic enzyme insufficiency is suspected alongside celiac disease, but not routinely recommended.","evidence":"Limited"}]
Primary treatment for: Exocrine pancreatic insufficiency
Also treats: Chronic pancreatitis, Cystic fibrosis, Pancreatic cancer, Post-pancreatic surgery, Steatorrhea
📋 Drug Information
| Generic Name(s) | Pancreatin (150mg) |
| Brand Name | sbz 10k capsule |
| Manufacturer | Charan Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | GASTRO INTESTINAL |
| Action Class | Digestive enzymes |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in the original container, tightly closed, away from heat, moisture, and direct light. Do not refrigerate unless specified on the label. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. |
| WHO Guideline | Not established from the available information. Guidelines for pancreatic enzyme replacement therapy are available from gastroenterology societies, but specific WHO recommendations are not verified here. |
| ICMR Guideline | Not established from the available information. Consult local guidelines for pancreatic enzyme replacement therapy. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by supplying exogenous pancreatic enzymes that are normally produced by a healthy pancreas. Pancreatin contains three main enzyme groups: lipases, which break down fats into fatty acids and glycerol; proteases, which break down proteins into peptides and amino acids; and amylases, which break down starches into simpler sugars. These enzymes are enteric-coated to survive the acidic environment of the stomach and are released in the alkaline environment of the small intestine. Once released, they mix with food and mimic the natural digestive process, allowing nutrients to be absorbed through the intestinal wall. This medicine does not treat the underlying pancreatic disease; it replaces the missing enzymes to improve digestion and nutrition.
Mechanism Steps
💡 How to Take sbz 10k capsule
Strength: Pancreatin 150 mg immediate-release tablet.
Dosage Information
| Adult Dosage | The dose of this medicine is individualized based on the severity of exocrine pancreatic insufficiency, the fat content of your diet, and your clinical response. It is usually taken with every meal and snack. The starting dose is often 500 to 1,000 lipase units per gram of fat consumed, but your doctor will determine the exact dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not adjust the dose without medical advice. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Doses are typically based on body weight and fat intake, and must be determined by a specialist. |
| Elderly Dosage | Elderly patients may use this medicine at the same doses as adults, but they should be monitored for nutritional status and any signs of malabsorption. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is required for renal impairment, as this medicine acts locally in the gastrointestinal tract and is not absorbed systemically. |
| Hepatic Impairment | No dose adjustment is required for hepatic impairment, as this medicine acts locally in the gastrointestinal tract and is not absorbed systemically. |
| Maximum Daily Dose | The maximum daily dose is individualized and should not exceed the level recommended by your doctor. High doses should be used with caution, especially in children with cystic fibrosis, due to the risk of fibrosing colonopathy. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of sbz 10k capsule
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Acarbose | Major | |
| Miglitinide | Major | |
| Antacids | Moderate | |
| Proton pump inhibitors | Moderate | |
| Iron supplements | Minor | |
| Folic acid | Minor |
🚨 Major Interactions
- Acarbose
- Miglitinide
⚡ Moderate Interactions
- Antacids containing calcium carbonate or magnesium hydroxide
- Proton pump inhibitors (e.g., omeprazole)
🍷 Alcohol Interaction
Alcohol may worsen pancreatitis and can reduce the effectiveness of this medicine. It is advisable to avoid alcohol while taking this medicine, especially if you have a pancreatic condition.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to pancreatin or porcine proteins.","Acute pancreatitis or acute flare of chronic pancreatitis.","Bowel obstruction or ileus.","Severe acute abdominal pain of unknown cause."]
⚠️ Warnings & Precautions
["Do not crush, chew, or hold the tablet in the mouth; swallow whole with water.","Take with food to ensure proper mixing and effectiveness.","High doses may cause fibrosing colonopathy, especially in children with cystic fibrosis; use the lowest effective dose.","Use with caution in patients with a history of bowel obstruction or gastrointestinal strictures.","Consult your doctor before use if you are pregnant, planning pregnancy, or breastfeeding.","Do not use after the expiry date.","Keep out of reach of children."]
🤱 Lactation Safety
Pancreatin is not absorbed into the bloodstream and is unlikely to pass into breast milk in significant amounts. It is generally considered safe during breastfeeding, but consult your doctor.
💊 Overdose Management
Overdose with this medicine is unlikely to cause serious harm because it acts locally in the gut. However, very high doses may cause nausea, vomiting, diarrhea, or abdominal pain. If you suspect an overdose, contact your doctor or a poison control center immediately. Treatment is supportive and symptomatic.
⏰ Missed Dose
If you miss a dose, take it with your next meal if it is almost time. If you remember long after the meal, skip the missed dose and continue with your regular schedule. Do not double the dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, and always swallow the tablet whole with plenty of water. Do not crush, chew, or hold the tablet in your mouth, because the enzymes can irritate the lining of your mouth and throat. Take this medicine with meals or snacks, as directed, so that the enzymes can mix with your food and help with digestion. Do not change the dose or stop taking this medicine without talking to your doctor first. Keep all follow-up appointments so your doctor can check how well the medicine is working and adjust the dose if needed. Tell your doctor if you have a history of bowel obstruction, pancreatitis flare-ups, or allergies to pork products. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits with your doctor before using this medicine. Store this medicine in its original container at room temperature, away from heat, moisture, and direct light. Keep it out of reach of children. Do not use this medicine after the expiry date printed on the pack. If you miss a dose, take it with your next meal if it is almost time, but never double the dose to make up for a missed one. Contact your doctor immediately if you notice any signs of a serious allergic reaction, such as swelling of the lips, tongue, or throat, or if you have severe abdominal pain.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more prone to nutritional deficiencies and should be monitored for weight loss, vitamin levels, and overall health. Dose adjustment is not usually needed, but individualization by a clinician is important.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before using this medicine. It is generally considered safe as it acts locally in the gut, but your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
After pancreatic surgery, this medicine is often prescribed to replace lost enzyme production. Follow your surgeon's and gastroenterologist's instructions for dosing and monitoring.
🦷 Dental Procedures
This medicine does not usually affect dental procedures. However, inform your dentist about all medicines you are taking. If you have mouth irritation from the medicine, tell your dentist.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine does not usually affect your ability to exercise. However, if you have abdominal pain or discomfort, avoid strenuous exercise until you feel better. Consult your doctor before starting any new exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is not expected to affect your ability to work or drive. However, if you experience dizziness or abdominal discomfort, avoid driving or operating heavy machinery until you feel well.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or an allergic reaction, stop the medicine and seek immediate medical attention. Your doctor will decide if and when to stop or change the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and necessary for people with chronic exocrine pancreatic insufficiency. Regular monitoring of nutritional status, vitamin levels, and growth in children is recommended. High doses may rarely cause fibrosing colonopathy, so the lowest effective dose should be used. Periodic review with your doctor is important to adjust the dose as your condition changes.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Eating a low-fat diet and small frequent meals can help manage symptoms, but does not replace enzyme therapy.
Evidence: Well-establishedFat-soluble vitamin supplements may be needed to correct deficiencies caused by malabsorption.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, people with chronic pancreatic conditions should stay up to date with routine vaccinations as advised by their doctor.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your hand luggage to avoid loss or temperature extremes. Store at room temperature and avoid direct sunlight. If crossing time zones, continue taking the medicine with meals as usual. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working during digestion, within 30 to 60 minutes after taking it with a meal. You may notice improvement in stool consistency and bloating within a few days to weeks.
A: No, this medicine must be taken with food to mix with the meal and aid digestion. Taking it without food reduces its effectiveness.
A: Yes, it is generally safe for long-term use when taken as prescribed. However, high doses should be monitored, especially in children, due to a rare risk of fibrosing colonopathy.
A: No, do not crush or chew the tablet. Swallow it whole with water to avoid mouth irritation and ensure proper release in the intestine.
🤔 Common Patient Concerns
🔄 Substitutes for sbz 10k capsule
View AllAlternative brands with exact same active ingredient:
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liprolase 10000 tabletViilbery Healthcare Pvt Ltd ₹150.00 30.4% CHEAPER
-
panstal capsuleCipla Ltd ₹165.47 23.3% CHEAPER
-
enzase 10000 tabletMSN Laboratories ₹168.00 22.1% CHEAPER
-
enzelo 150mg tabletZuventus Healthcare Ltd ₹185.00 14.2% CHEAPER
-
creafine 10000 capsuleSargas Life Sciences Pvt Ltd ₹210.00 2.6% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be taken without food.
Fact: This medicine must be taken with food to mix with the meal and aid digestion. - Myth: This medicine is a cure for pancreatitis.
Fact: This medicine replaces missing enzymes but does not cure the underlying pancreatic disease. - Myth: Crushing the tablet makes it easier to swallow and works faster.
Fact: Crushing or chewing the tablet can cause mouth irritation and reduce effectiveness. Always swallow whole.
🔄 Alternative Options
Generic Alternatives
- Pancreatin 150 mg immediate-release tablets from other manufacturers.
Brand Alternatives
- Enzase 10000 tablet